The effects of cAMP are transduced by two intracellular cAMP receptors, PKA and EPAC, which are both present in all tissues. Understanding the individual roles and contributions of these two receptors is important for understanding cAMP signaling. Currently, there are no specific antagonists or agonists for EPAC, making it difficult to study. However, identifying regulators of EPAC could lead to new therapeutic strategies for diseases such as diabetes, heart disease, and cancer. Is the molecule effective to this assay?