COC12CCC3(CC1C(C)(O)C(C)(C)C)[C@H]1Cc4ccc(OC5OC(C(=O)O)[C@@H](O)C(O)[C@H]5O)c5c4[C@@]3(CCN1CC1CC1)C2O5
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?