COc1ccc(Cc2c(-c3ccc(C)cc3)n[nH]c(=O)c2C2C(=O)N(c3ccccc3)N=C2c2ccccc2)cc1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?