Cc1cccc(C)c1-n1nnnc1C(c1cc2ccccc2o1)N1CCC(n2c(O)nc3ccccc32)CC1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?