CC(=O)Nc1cccc(-c2ccnc3c2CC(C)(C(=O)Nc2ccc(Cl)cc2)O3)c1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?