Cc1ccc(C)c(N2C(=O)C(=O)C(c3nc4ccccc4s3)/C(=N/N)C2=O)c1
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?