Cc1cc(Cl)ccc1NC(=O)/C(=N\NC(C)(C)C)C(C#N)c1nc(-c2ccc([N+](=O)[O-])cc2)cs1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?