COc1cccc(C(=O)N2CCN(C(=O)C3COc4ccccc4O3)CC2)c1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?