CCOc1ccc(C2C(C(=O)Nc3ccc(OC)cc3)=C(C)Nc3nc(CCCO)nn32)cc1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?