Cc1cc(=O)oc2cc(NC(=O)C(C)N3C(=O)C4CCCCC4C3=O)ccc12
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?