O=C(/C=C/c1ccc(F)cc1)Nc1nc2n(n1)C(c1ccc(Cl)cc1)C=C(c1ccccc1)N2
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?