COc1ccc([C@]23CCN4COC[C@@H]([C@H]42)C2(CC3)OCC(C)(C)CO2)cc1OC
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?