CCOC(=O)C1(C(=O)OCC)[C@H]2CCC[C@H]3ON=C([C@@H]23)[C@@H]1c1ccccc1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?