CC(=O)NNc1nc(C)c(C(=O)/C=C/c2ccc(/C=C/C(=O)c3sc(NNC(C)=O)nc3C)cc2)s1
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?