COc1ccc2[nH]c3c(c2c1)CCN1C(=O)C(CC(=O)NCC24C[C@H]5C[C@@H](C2)C[C@@H](C4)C5)C[C@H](C(=O)N(C(C)C)C(C)C)[C@@]31C
Lipinski's rule of five describes molecular properties important for a drug's pharmacokinetics in the human body. How many rules of Lipinski's rule of five does this molecule break?