COc1ccc(C(=O)CC2=Nc3nnc(CCCCCCCc4nnc5n4C(=O)C(CC(=O)c4ccc(OC)cc4)=N5)n3C2=O)cc1
A rotatable bond is defined as any single non-ring bond, attached to a non-terminal, non-hydrogen atom. Amide C-N bonds are not counted because of their high barrier to rotation.  How many rotatable bonds does the molecule have?