COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)c1ccc(CNC(=O)/C=C/c2cccc(Oc3ccccc3)c2)cc1
Lipinski's rule of five describes molecular properties important for a drug's pharmacokinetics in the human body. How many rules of Lipinski's rule of five does this molecule break?