Oc1nc2c(c(-c3ccc(F)cc3)n1)COC/C2=C\c1ccc(F)cc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?