COc1cc([C@@H]2c3cc4c(cc3[C@@H](Nc3ccc(C(=O)N[C@H]5CCc6cc(OC)c(OC)c(OC)c6-c6ccc(SC)c(=O)cc65)cc3)[C@H]3COC(=O)[C@@H]32)OCO4)cc(OC)c1O
In analogy to the rule of five, it has been proposed that ideal fragments should follow the rule of three, in which the molecular weight of a fragment is <300, the c LogP is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?