COC(=O)C(Cc1nc2ccccc2nc1O)/C(=N\NC(C)(C)C)C(=O)Nc1c(C)cc(Br)cc1C
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?