O=C(N[C@H]1CC2(C=C(I)C(=O)C(I)=C2)OC1=O)OCc1ccccc1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?