COc1ccc(CCn2c(C)cc(C(=O)CN3C(=O)C(=O)N(Cc4ccco4)C3=O)c2C)cc1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?