Cc1nc(-n2nc(-c3ccccc3)cc2-c2ccccc2)sc1C(=O)CC(=O)C(=O)Nc1ccc(O)cc1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?