COc1cc([C@@H]2c3cc4c(cc3[C@@H](c3c(O)cc(O)c5c3O[C@H](c3ccc(O)c(O)c3)[C@H](OC(=O)c3cc(O)c(O)c(O)c3)C5)[C@H]3COC(=O)[C@H]23)OCO4)cc(OC)c1O
Lipinski's rule of five is a rule of thumb to evaluate drug-likeness or determine if a chemical compound with a certain pharmacological or biological activity has chemical properties and physical properties that would make it a likely orally active drug in humans. It includes: No more than 5 hydrogen bond donors (the total number of nitrogen–hydrogen and oxygen–hydrogen bonds); No more than 10 hydrogen bond acceptors (all nitrogen or oxygen atoms); A molecular mass of less than 500 daltons; An octanol-water partition coefficient (log P) that does not exceed 5. How many rules of Lipinski's rule of five does this molecule violate?