COC(=O)C1(C)C=CC(=O)C2(C)C1C(O)C1OC3CC(c4ccoc4)C(C)=C3C1(C)C2CC(=O)[O-].[Na+]
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?