Cc1cc(C)c(C2=NO[C@H]3C(=O)N(c4ccc(Cc5ccc(N6C(=O)[C@H]7ON=C(c8c(C)cc(C)cc8C)[C@H]7C6=O)cc5)cc4)C(=O)[C@@H]23)c(C)c1
In analogy to the rule of five, it has been proposed that ideal fragments should follow the rule of three, in which the molecular weight of a fragment is <300, the c LogP is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?