Cc1nc2scc(C)n2c(=O)c1S(=O)(=O)Nc1cc(C(F)(F)F)ccc1Cl
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?