COC(=O)[C@@H]1C[C@H]2OC(=O)CC[C@]2(C)O[C@H]1[C@H]1O[C@@](C)(O)CCC[C@H]1C
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?