CCOC(=O)c1sc(N/N=C/c2cc(Br)c(O)c(OC)c2)nc1C
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?