COc1ccc2c3c1O[C@H]1C(OC)C=CC4C(C2)N(Cc2cccs2)CCC341.O=C(O)/C=C/C(=O)O
Lipinski's rule of five describes molecular properties important for a drug's pharmacokinetics in the human body. How many rules of Lipinski's rule of five does this molecule break?