CC(=O)Nc1cc(-c2ccccc2N(C)C)cn2c(-c3cccc(C(F)(F)F)c3)cnc12
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?