COc1cc(/C=C2\N=C(c3ccccc3)N(c3ccc4c(c3)Sc3cc(N5C(=O)/C(=C/c6cc(OC)c(OC)c(OC)c6)N=C5c5ccccc5)ccc3N4)C2=O)cc(OC)c1OC
Lipinski's rule of five describes molecular properties important for a drug's pharmacokinetics in the human body. How many rules of Lipinski's rule of five does this molecule break?