O=C(O[C@@H]1[C@@H]2O[C@]2(CO)[C@H]2[C@H](OC3OC(CO)C(O)C(O)C3O)OC=C[C@@H]12)c1ccc(O)c(O)c1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?