COc1cc2c(c3c1c(=O)c1ccccc1n3C)C=CC1(CCCC1)O2
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?