CN1c2ccccc2C2=C(c3ccccc3)CC[C@@H](C(=O)N3C4C[C@H]5CC[C@@]4(CS3(=O)=O)C5(C)C)[C@@H]21
In analogy to the rule of five, it has been proposed that ideal fragments should follow the rule of three, in which the molecular weight of a fragment is <300, the c LogP is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?