O=C1C[C@H]2[C@H](c3ccc(Br)cc3)[C@H]3C(=O)c4ccccc4NC(=O)[C@@H]3[C@@]2(O)c2ccccc2N1
In analogy to the rule of five, it has been proposed that ideal fragments should follow the rule of three, in which the molecular weight of a fragment is <300, the c LogP is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?