COc1cc(/C=C/C(=O)OC[C@H](Br)[C@H](OC(C)=O)c2ccc3c(c2)OCO3)cc(OC)c1OC
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?