C=CCn1c(SCC(=O)N(CC)C2CCS(=O)(=O)C2)nc2cc(C(=O)O)ccc2c1=O
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?