CCOC(=O)c1cc(C2(O)CCN(CC(C)CC)C2=O)c(-c2cc(C)no2)[nH]1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?