COC(=O)C1C2CC3C(OC(=O)C31)C2OC(=O)[C@](OC)(c1ccccc1)C(F)(F)F
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?