Cc1ccc(C(=O)CCC(=O)OCC(=O)N2c3ccccc3NC(=O)C2(C)C)cc1
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?