CCc1ccc(Cc2ccc(CC)c(NC(=O)C(=O)C3NC(=S)NC3=O)c2CC)c(CC)c1NC(=O)C(=O)C1NC(=S)NC1=O
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?