CC1(C)CC(=O)C2=C(C1)N(c1ccccc1)C1(O)C=CC(O)=C3C(=O)c4ccccc4C(=O)C321
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?