COC(=O)C1C(=O)C=CN([C@H](C)c2ccccc2)[C@@H]1Cc1ccc(OC)c(OCc2ccccc2)c1I
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?