COC(=O)/C=C1\C(=O)C=C2[C@@H]3C[C@H]4C[C@H](CC[C@@]4(C)N21)C3(C)NC(C)=O
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?