O=C1Nc2cc(C(=O)N3CCOCC3)ccc2S/C1=C/c1ccccc1F
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?