CCc1ccccc1NC(=O)c1ccc2c(O)c(S(=O)(=O)c3ccc(OC)cc3)c(O)nc2c1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?