CCCn1c(N)c(N2CCCCC2)c(=O)n(CC(=O)Nc2ccccc2C(F)(F)F)c1=O
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?