COC1CC2C=CC3C4OC2(/C(C)=C/C(C)C(C(C)O)OC1=O)C3C(O)C(C)C4OC(=O)c1ccc[nH]1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?