O=C(Cc1cccc(NC(=O)C2CCCN(C(=O)C3CCC3)C2)c1)Nc1cccc(C(=O)N2CCOCC2)c1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?