Cc1ccc(O)c(-c2csc(NCN3CCN(CNc4nc(-c5cc(C)ccc5O)cs4)CC3)n2)c1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?