COc1cc(/C=C/C(=O)OCC(=O)c2ccc3c(c2)NC(=O)CO3)ccc1OC(F)F
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?