Cc1cccc2c(=O)[nH]c3c(-c4nc(-c5ccc(Cl)cc5)cs4)c(O)cn3c12
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?