COc1cc([C@@H]2c3cc4c(cc3[C@@H](Nc3ccccc3C(=O)c3ccccc3)[C@H]3COC(=O)[C@@H]32)OCO4)cc(OC)c1OC
PSA is a commonly used medicinal chemistry metric for the optimization of a drug's ability to permeate cells. Please predict psa of this molecule.