COC(=O)C1=C(C(=O)OC)C23CC1C1C(C(=O)OC)=C(C(=O)OC)C12C1C=CC3C2C(=O)OC(=O)C21
Lipinski's rule of five describes molecular properties important for a drug's pharmacokinetics in the human body. How many rules of Lipinski's rule of five does this molecule break?