COc1cc(OC)cc(-c2c(C#Cc3ccsc3)c3cc(-c4cccc5[nH]cc(C=O)c45)ccc3n2C)c1
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?