Cc1cc2nc3c(C(OC4OC(CO)C(O)C(O)C4O)C(O)CO)nn(-c4ccc(F)cc4)c3nc2cc1C
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?