CC(=O)O[C@H]1C(=O)[C@]2(C)[C@@H](O)C[C@H]3OC[C@@]3(OC(C)=O)[C@H]2[C@H](OC(=O)c2ccc(F)cc2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)c3ccccc3)c3ccccc3)C(C)=C1C2(C)C
Lipinski's rule of five is a rule of thumb to evaluate drug-likeness or determine if a chemical compound with a certain pharmacological or biological activity has chemical properties and physical properties that would make it a likely orally active drug in humans. It includes: No more than 5 hydrogen bond donors (the total number of nitrogen–hydrogen and oxygen–hydrogen bonds); No more than 10 hydrogen bond acceptors (all nitrogen or oxygen atoms); A molecular mass of less than 500 daltons; An octanol-water partition coefficient (log P) that does not exceed 5. How many rules of Lipinski's rule of five does this molecule violate?