COC(=O)/C1=C/C=C\C[C@@]2(C)CC(c3ccoc3)OC(=O)[C@@H]2CC[C@H]1C
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?