COc1cc(C2SC(C)C(=O)N2c2ccc(-c3csc(NS(=O)(=O)c4ccc(Cl)c(OC)c4)n3)cc2)ccc1O
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?