COc1ccc(/C(CC2OC(=O)c3ccccc32)=N\NC(=O)C[N+](C)(C)C)cc1.[Cl-]
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?