Cc1ccc(CNC(=O)c2cc(-c3ccc(C)cc3)nc3n[nH]c(-c4ccc(F)cc4)c23)cc1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?