COc1cccc(NC(=O)CN(C)C(=O)c2ccc3c(c2)CC(c2ccccc2)OC3=O)c1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?