Cc1nc(SCc2nc3cc(Br)ccc3[nH]2)c2oc3ccccc3c2n1.O=C(O)C(F)(F)F
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?