CCOC(=O)/C(C#N)=C1\c2c([nH]c(=S)[nH]c2=O)Oc2ccc3ccccc3c21
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?