CC1=NN(c2cccc(Cl)c2)C2(/C1=C/c1ccccc1)C(Cl)C(=O)N2c1nc2ccccc2s1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?