COc1ccc(-c2nn(-c3ccccc3)cc2/C=C/C(=O)N(C)CC(=O)Nc2cccc(F)c2)cc1OC
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?