CCCCCCn1c(=O)n2n(c1=O)C[C@@]1(O)CN(S(=O)(=O)c3ccc(C)cc3)C[C@@]1(OC(=O)NC1CCCC1)C2
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?