COc1cc(-c2coc3c(OC)c(OC4OC(CO)C(O)C(O)C4O)c(OC)cc3c2=O)cc(OC)c1C
Lipinski's rule states that, in general, an orally active drug has no more than one violation of the following criteria: No more than 5 hydrogen bond donors (the total number of nitrogen–hydrogen and oxygen–hydrogen bonds); No more than 10 hydrogen bond acceptors (all nitrogen or oxygen atoms)
A molecular mass less than 500 daltons; A calculated octanol-water partition coefficient (Clog P) that does not exceed 5. This molecule violates how many of Lipinski's five laws?