CC(C)c1csc(CN2CCC(C(=O)Nc3cccc(-c4ccco4)c3)CC2)n1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?