CC1(C(=O)NS(=O)(=O)c2cccc(C#N)c2)CCN1C(=O)C1(c2ccc(Cl)cc2)CC1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?