COC1=C(N)C(=O)C2=C(CCC(c3nc(C(=O)O)c(C)c(-c4ccc(OC)c(OC)c4O)c3N)N2)C1=O
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?