COC(=O)[C@@]1(C)CCC[C@]2(C(=O)O)C3Cc4occc4[C@H](C)[C@@H]3CCC12
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?