CCCN1CN([C@@H](C(=O)N[C@@H]2C(=O)N3C2SC(C)(C)C3C(=O)O)c2ccccc2)CSC1=S
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?