COc1ccc(CN2C(=O)C(Cc3cc(OC)c(OC)c(C)c3OC)NC(=O)/C2=C/c2cc(OC)c(OC)c(C)c2OC)cc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?