O=C(O)c1c2c(cc3c1CC1(Cc4cc5c(cc4C1=O)CCC5)C3)CCC2
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?