COc1ccc(NC(=O)N(C)C[C@@H]2Oc3c(NC(=O)Nc4c(C)noc4C)cccc3C(=O)N([C@@H](C)CO)C[C@@H]2C)cc1
Molecules with a polar surface area of greater than 60 angstroms squared (Å2) is hard to pass brain blood barrier. What's the psa of this molecule?