CC1(C)CC(=O)c2cc(-c3nc(-c4ccc(F)cc4)cs3)c(=O)[nH]c2C1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?