Cc1cccc(CNC(=O)C(C)n2nc(C)c3c(C)n(-c4ccccc4)nc3c2=O)c1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?