COc1ccc(C(=O)OCC2OC(n3cnc4c(=S)nc[nH]c43)C(OC(=O)c3ccc(OC)cc3)C2OC(=O)c2ccc(OC)cc2)cc1
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?