C#CC(O)/C=C/CCCCCCC#CC/C=C\CC#CCCCCCC/C=C/C(O)C#C
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?