COc1ccc(C(CC(=O)c2ccc(O)cc2)C(C(=O)c2ccc(O)cc2)C(c2ccc(OC)cc2)C2C(=O)NC(=S)NC2=O)cc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?