COc1ccc(CNC(=O)C(C)OC(=O)c2cccc(N(C)C)c2)cc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?