COC(=O)C([C@H]1CC[C@H](OCc2ccccc2)[C@@]1(O)COCc1ccccc1)C(C)(O)CCc1ccccc1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?