COc1cccc(-c2cccc(-c3nc(C(=O)NCc4ccc(Oc5ccccc5)cc4)cc4c3[C@H](CCO)N([S+]([O-])C(C)(C)C)C4)c2)c1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?