CC1=C/C(=N\NC(N)=S)C(C(O)(C(F)(F)F)C(F)(F)F)C(C)(C)C1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?