CC(CCC(=O)OCC1OC(C#Cc2ccccc2)C=CC1Oc1ccc(C)cc1)=NOC(C)c1cn(C2COCC2O)nn1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?