COc1ccc(/C(Cl)=C(\C=O)c2ccc([N+](=O)[O-])cc2)cc1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?