NC(CCC(=O)O)C(=O)NC(Cc1ccc(N(CCCl)CCCl)cc1)C(=O)O.O=C(O)C(F)(F)F
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?