CCN(C(=O)CSc1nc2cc(C)ccc2[nH]1)C1CCS(=O)(=O)C1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?