S=c1nc(Nc2ccc(Br)cc2)c2c3c(sc2[nH]1)CN(N1CCc2c(sc4[nH]c(=S)nc(Nc5ccc(Br)cc5)c24)C1)CC3
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?