C[C@@H]1NC(=O)[C@@]2(C)[C@@H](c3ccccc3)[C@H]3COc4ccc(Cl)cc4[C@@H]3N2C1=O
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?