COc1ccc2c3c1O[C@H](c1ccc(O)cc1)[C@H]3[N+](C)(C)CC2.[I-]
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?