Cc1c(NS(=O)(=O)c2cc(C(=O)N(C)Cc3ccccc3)ccc2Cl)c(=O)n(-c2ccccc2)n1C
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?