CCn1cc(CN2CCN(Cc3ccc(OC)c(C)c3C)C(CCO)C2)c(C)n1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?