COC(=O)C1=C(C(=O)OC)C2N(CC=C(C)C)c3ccccc3C23CCC(=O)N(Cc2cccc(C(F)(F)F)c2)C3=N1
PSA is a commonly used medicinal chemistry metric for the optimization of a drug's ability to permeate cells. Please predict psa of this molecule.