Cc1ccc(Oc2c(C(F)(F)F)oc3c(CN4CCCCC4C)c(O)ccc3c2=O)cc1
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?