Cc1cc(C)c(C[C@H]2COC(=O)[C@]2(O)Cc2c(C)cc(C)cc2C)c(C)c1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?