O=C1c2ccccc2[C@@H]2C[C@H](NC34CC5CC(CC(C5)C3)C4)[C@@H](O)CCN12
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?