O=C1/C(=C/c2ccccc2O)N=C(c2ccccc2)N1C1Nc2cc3c(cc2S1)NC(N1C(=O)/C(=C/c2ccccc2O)N=C1c1ccccc1)S3
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?