COc1ccc(C2Nc3ccccc3C(=O)N2c2ccccc2F)cc1COc1ccc(NC(C)=O)cc1
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?