COc1ccc(-c2nc(N)nc(C(F)(F)F)c2-c2csc(C)n2)c(O)c1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?