O=C(/C=C\c1ccccc1)Oc1ccc(/C=C2\CCC/C(=C\c3ccc(OC(=O)/C=C\c4ccccc4)cc3)C2=O)cc1
Molecules with a polar surface area of greater than 60 angstroms squared (Å2) is hard to pass brain blood barrier. What's the psa of this molecule?