COc1ccc(/C=C/C(=O)N[C@@H]2C(=O)N3[C@@H](C(=O)[O-])C(C)(C)S[C@H]23)cc1OC.[Na+]
In analogy to the rule of five, it has been proposed that ideal fragments should follow the rule of three, in which the molecular weight of a fragment is <300, the c LogP is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?