COc1ccccc1CN1CC(C(=O)N(C)CCc2nc3cc(F)ccc3[nH]2)CCC1=O
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?