CCOC(=O)C1(c2ccccc2)CCN(CC(O)c2ccc(NC(C)=O)cc2)CC1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?