COc1cccc(-c2cccc(-c3nc(C(=O)Nc4ccc(-c5ccccc5)cc4)cc4c3[C@H](CCO)N([S+]([O-])C(C)(C)C)C4)c2)c1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?