Cn1c(CN2CCN(c3ccccc3NS(C)(=O)=O)CC2)nc2ccccc21
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?