COC(=O)[C@@H]1[C@H]2CC[C@]3(C)[C@@H](OC(C)=O)CC[C@H]3[C@@H]2CC[C@H]1C1(C)SCCS1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?