CC(Oc1cc2oc(=O)c3c(c2cc1Cl)CCC3)C(=O)NC[C@H]1CC[C@H](C(=O)O)CC1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?