O=C1Nc2cc(C(=O)NCC3CCCO3)ccc2S/C1=C/c1ccccc1F
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?