COc1cc(/C=C2\C(C)=NN(c3cccc(Cl)c3)C23C(Cl)C(=O)N3c2nc3ccccc3s2)ccc1O
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?