COc1cc(/C=C2/C[C@H]3[C@@H]4CCC5=CC(=O)CC[C@]5(C)[C@H]4CC[C@]3(C)NC2=O)cc(OC)c1OC
PSA is a commonly used medicinal chemistry metric for the optimization of a drug's ability to permeate cells. Please predict psa of this molecule.