COc1ccc(C2C=C(c3ccccc3)Nc3nc(NC(=O)c4cccc([N+](=O)[O-])c4)nn32)cc1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?