CC[C@@H]1CC[C@@H]2[C@H](CC[C@]3(C)[C@@H](OS(=O)(=O)c4ccc(C)cc4)CC[C@@H]23)[C@H]1COS(=O)(=O)c1ccc(C)cc1
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?