COC1CC2C=CC3C4OC2(/C(C)=C/C(C)C(C(C)O)OC1=O)C3C(O)C(C)C4OC(=O)c1ccc[nH]1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?