CC(C)(C)OC(=O)N1CCC(c2c(C(=O)NCCN3CCc4ccccc4C3)cnn2-c2ccc(F)cc2F)CC1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?