O=C(COc1ccc(OCC(=O)N2C(=O)CC/C2=N\c2ccc(Cl)cc2)cc1)N1C(=O)CS/C1=N\c1ccc(Cl)cc1
Lipinski's rule of five describes molecular properties important for a drug's pharmacokinetics in the human body. How many rules of Lipinski's rule of five does this molecule break?