COc1ccc(N2C(=O)[C@H]3c4[nH]c5ccccc5c4[C@H]4CCC(C)C[C@H]4[C@H]3C2=O)cc1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?