CCOC(=O)c1ccccc1NC(=O)Cn1c(=O)n(Cc2nc(C)no2)c(=O)c2ccccc21
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?