O=C(Cc1nccc2c1[nH]c1ccccc12)OC1C#CCSCC#C/C=C\1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?