C=C1CCC[C@]2(C)C[C@H]3OC(=O)C(CN4CC(C)OC(C)C4)[C@H]3C[C@@H]12
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?