COc1ccc(/C=C(\C#N)c2nc(N)nc(N3N=C(C)CC3(C)C)n2)c(O)c1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?