COc1c(-c2nc3ccc(N4CCN(C)CC4)nc3[nH]2)cc(OC)c2[nH]c(CO)nc12
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?