CN(C)c1ccc(/C=C(\NC(=O)c2ccccc2)C2=NC(CCC(=O)O)C(=O)O2)cc1
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?