COc1ccc2c(c1)OC[C@H]1[C@H]2N2C(=O)c3ccc(C)cc3NC(=O)[C@@]2(C)[C@H]1c1ccccc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?