COC(=O)c1ccc2c(c1)CC1(C2)Cc2cc3c(c(C(=O)OC)c2C1)CCCC3
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?