COc1cc2c(cc1O)CCN[C@@]21CS[C@H]2c3c(OC(C)=O)c(C)c4c(c3C(COC1=O)N1C2C2NC(Cc3cc(C)c(OC)c(O)c32)[C@@H]1C#N)OCO4
Molecules with a polar surface area of greater than 60 angstroms squared (Å2) is hard to pass brain blood barrier. What's the psa of this molecule?