COc1ccc(S(=O)(=O)N(C)[C@H]2C[C@H]3c4cc(Oc5ccccc5C)ccc4CCN3C(=O)[C@H]2[C@H](C)O)cc1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?