COc1ccc(C2CC(=O)CC(c3ccc(OC)cc3)C23C(=O)NC(=O)NC3=O)cc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?