Cc1nc2c(c(C)nn2C(C)(C)C)c(C)c1CCC(=O)Nc1ccc(Br)cc1Br
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?