O=C(O)/C=C\C(=O)O.O=C1NCN(c2ccccc2)C12CCN(CCCN1CCN(CCOC(c3ccccc3)c3ccccc3)CC1)CC2
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?