CC1=C(CC2C(=O)N(c3ccccc3)S(=O)(=O)NC2C)C(=O)N(c2ccccc2)S(=O)(=O)N1C
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?