CC(C)NC(=O)N(C)C[C@H]1Oc2c(NC(=O)Cc3ccccc3)cccc2C(=O)N([C@H](C)CO)C[C@@H]1C
In analogy to the rule of five, it has been proposed that ideal fragments should follow the rule of three, in which the molecular weight of a fragment is <300, the c LogP is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?