CC1=C(C(=O)Nc2ccccc2)C(c2ccc(C)o2)C(C#N)=C(SCc2ccccc2)N1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?