Cc1ccc2oc3c(c(=O)c2c1)C(c1ccc(F)cc1)N(Cc1ccc2c(c1)OCO2)C3=O
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?