COc1ccc(C(=O)NC(NC(=O)c2ccc(OC)c(OC)c2)c2ccccc2F)cc1OC
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?