COc1ccc(OC)c(N(C(=N)Nc2nc(C)cc(C)n2)S(=O)(=O)c2ccc(NC(C)=O)cc2)c1
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?