COc1ccc(Cc2nnc(NC(=O)C3CC(=O)N(CCc4ccc(F)cc4)C3)s2)cc1OC
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?