C[C@@]12CC(=O)NC1N(C(=O)c1cccc(C(F)(F)F)c1)C(c1ccccc1OC(=O)c1cccc(C(F)(F)F)c1)C2
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?