COc1cccc(OC)c1Cn1nnc2c(O)nc(C3CCN(C(=O)c4ccccc4)CC3)nc21
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?