Cc1n[nH]c(O)c1C(c1cc2c(cc1Br)OCO2)c1c(C)n[nH]c1O
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?