Cn1c(=O)n(C)c2cc(NS(=O)(=O)c3ccc(Cl)cc3)c(NCc3ccccc3)cc21
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?