COc1ccc(C(=O)C(C)N(C(=O)c2ccc(Cl)cc2Cl)N2C(=O)C3C4C=CC(C4)C3C2=O)cc1
Molecules with a polar surface area of greater than 60 angstroms squared (Å2) is hard to pass brain blood barrier. What's the psa of this molecule?