COC(=O)c1cc2oc3ccccc3c2n1CC(=O)Nc1ccc(OC)c(OC)c1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?