COC(=O)c1cn(NC(=O)c2cc(OC)c(OC)c(OC)c2)c(=O)c2ccccc12
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?