CCn1ccnc1[C@@H]1C[C@H]2CN(c3ccccc3OC)C(=O)[C@]23CCCN13
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?