COc1ccc(-c2ccc(OC)c([C@H]3[C@H]4C=CC[C@@H](C)[C@@H]4C(=O)N3Cc3ccccc3)c2)cc1
Lipinski's rule of five describes molecular properties important for a drug's pharmacokinetics in the human body. How many rules of Lipinski's rule of five does this molecule break?