CCCOc1ccc(N2C(=O)C3C(C(C)C)NC4(C(=O)c5ccccc5C4=O)C3C2=O)cc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?