O=C(Nc1nnc(C(F)(F)F)s1)c1ccc(N2C(=O)C3C4C=CC(C4)C3C2=O)cc1
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?