Cc1cccc(-n2nc3c(c2NC(=O)C2CC2)CS(=O)(=O)C3)c1C
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?