CCCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCN(C)C)C23C(=O)N(C)c2ccccc23)cc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?