COc1c(C)cc(S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2)c(C)c1C
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?