COc1cccc(CSc2nc(-c3ccccc3F)nc3c2Cc2c(CO)cnc(C)c2O3)c1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?