COc1ccc(N(C)C(=O)C2CCCN2S(=O)(=O)c2cccc3nsnc23)cc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?