Cc1cc(C)nc(Sc2nc(Nc3ccccc3)nc(Sc3nc(C)cc(C)n3)n2)n1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?