O=C(Nc1ccc(C(=O)N2CCC(O)(c3ccc(Cl)c(C(F)(F)F)c3)CC2)cc1)c1ccc(Br)o1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?