COc1ccc(OC)c(N2C(N)=C(C#N)C(c3ccc(OC)c(O)c3)C3=C2CC(C)(C)CC3=O)c1
LogP, or octanol-water partition coefficient, is a measure of how hydrophilic or hydrophobic a molecule is. What is the negative logarithm of the partition coefficient of this molecule?