CCOc1cc(C2C3=C(O)CCCC3=NC3=C2C(=O)CCC3)ccc1OCCO
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?