O=c1cc(-c2ccccc2Cl)oc2c(NS(=O)(=O)c3cccc4nsnc34)ccc(O)c12
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?