COc1ccc(-c2[nH]nc3c2C2(C(=O)N(CC(=O)O)c4ccccc42)C(C#N)=C(N)O3)cc1OC
Lipinski's rule of five describes molecular properties important for a drug's pharmacokinetics in the human body. How many rules of Lipinski's rule of five does this molecule break?