COc1ccc2c3c(c(=O)oc2c1)[C@H]1O[C@](CCCCN2C(=O)c4ccccc4C2=O)(Cc2c1ccc1ccccc21)O3
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?