COc1ccc2c(c1)OC[C@H]1[C@H]2N2C(=O)CN(Cc3ccc(Cl)cc3)C(=O)[C@@]2(C)[C@H]1c1ccccc1
In analogy to the rule of five, it has been proposed that ideal fragments should follow the rule of three, in which the molecular weight of a fragment is <300, the c LogP is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?