CCOC(=O)c1c(-c2ccc(C)o2)csc1NC(=S)NC(=O)c1ccccc1Br
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?