Cc1ncc(CN2CCCC(C(=O)c3cccc(Cl)c3)C2)s1
Lipinski's rule of five is a rule of thumb to evaluate drug-likeness or determine if a chemical compound with a certain pharmacological or biological activity has chemical properties and physical properties that would make it a likely orally active drug in humans. It includes: No more than 5 hydrogen bond donors (the total number of nitrogen–hydrogen and oxygen–hydrogen bonds); No more than 10 hydrogen bond acceptors (all nitrogen or oxygen atoms); A molecular mass of less than 500 daltons; An octanol-water partition coefficient (log P) that does not exceed 5. How many rules of Lipinski's rule of five does this molecule violate?