COC(=O)c1c(C)sc(-c2c(-c3cccc(OC)c3)[nH]c3c2c(=O)[nH]c(=O)n3C)c1O
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?