CC(NC(=O)C1CCC(CNS(=O)(=O)c2ccc3c(c2)C(C)(C)C(=O)N3C)CC1)c1ccccc1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?