COC(=O)C1=COC(C)C2CN3CCc4c([nH]c5cc(OC)c(OC)cc45)C3CC12.O=C(O)CC(O)(CC(=O)O)C(=O)O
PSA is a commonly used medicinal chemistry metric for the optimization of a drug's ability to permeate cells. Please predict psa of this molecule.