COc1cc2c(cc1OC)C(c1cc3cc(OC)c(OC)cc3nc1O)N(C(=O)C1CC1)CC2
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?