COc1ccc(OC)c(-c2nc(C(N)=O)c3c(n2)n(-c2ccc4c(c2)OCO4)c(=O)n3C)c1
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?