COc1ccc(-c2nc(NC(=O)C3CC(=O)N(c4ccc5c(c4)OCCO5)C3)sc2C)cc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?