CC(C)(C)c1ccc(Oc2cccc(C3CC(=O)C(C4NCCc5ccccc54)C(=O)C3n3cncn3)c2)cc1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?