Cc1c(NS(=O)(=O)c2ccc3[nH]c(COc4ccccc4Cl)nc3c2)c(=O)n(-c2ccccc2)n1C
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?