Cc1c(Cc2ccccc2)c(=O)oc2cc(OC(C)C(=O)NC[C@H]3CC[C@H](C(=O)O)CC3)c(Cl)cc12
Molecules with a polar surface area of greater than 60 angstroms squared (Å2) is hard to pass brain blood barrier. What's the psa of this molecule?