COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)C1CCCN(S(=O)(=O)c2ccc(C)cc2)C1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?