Cc1ccc(Oc2c(C(F)(F)F)oc3c(CN4CCCCC4)c(O)ccc3c2=O)cc1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?