COc1cc2c(cc1OC)CN(CC(=O)Nc1cccc(C(F)(F)F)c1)CC2
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?