COC(=O)C1OC(=O)C2OC23[C@@]1(C)CCC1[C@@]3(C)C(OC(C)=O)CC2C(C)(C)C(=O)CC[C@@]21C
Lipinski's rule of five describes molecular properties important for a drug's pharmacokinetics in the human body. How many rules of Lipinski's rule of five does this molecule break?