C[C@]12CCC3[C@@H](CC[C@H]4NC(=O)C=C[C@]34C)[C@@H]1CCC2C(=O)Nc1cc(C(F)(F)F)ccc1C(F)(F)F
Molecules with a polar surface area of greater than 60 angstroms squared (Å2) is hard to pass brain blood barrier. What's the psa of this molecule?