COC(CNC(=O)c1cccc(-n2c(=S)[nH]c3cc(Cl)ccc3c2=O)c1)OC
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?