COc1ccc(NC(=O)COC(=O)/C=C/c2ccccc2[N+](=O)[O-])cc1OC
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?