O=C(CCCn1c(SCC(=O)Nc2ccccc2C(F)(F)F)nc2ccccc2c1=O)NCC1CCCO1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?