COc1ccc(C2/C=C\CC(NC(=O)OCC3c4ccccc4-c4ccccc43)CC(=O)N2Cc2cccc(F)c2)cc1
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?