COc1ccc(CNC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccc(F)cc2)S3(=O)=O)cc1OC
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?