COc1ccc(C(=O)Nc2nc(-c3ccccc3)c(C(C)=O)s2)c(OC)c1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?