COC(=O)CC1C2(C)CC34OC5(C)O[C@@]6(C7/C(=C(/O)C(C)C)C(=O)OC(c8ccoc8)[C@]7(C)C(OC(C)=O)C(OC(C)=O)[C@]6(O5)[C@@]13C)C(OC(C)=O)[C@]4(O)C2OC(=O)C(C)C
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?