Cc1ccc2nc(-c3ccc(NC(=O)CN4C(=O)NC(C)(c5ccc(OC(F)F)cc5)C4=O)cc3)sc2c1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?