COc1ccc(-c2nc3c(c4c2C[C@H](c2ccccc2)OC4)CN(C(=O)C2CCCCC2)CC3)c(C)c1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?