CCOC(=O)c1c(N=C(S)Nc2ccccc2)sc2c1CCN(CCc1ccccc1)C2
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?