CCO[C@@H]1OC(C(=O)N2CCN(Cc3ccc4c(c3)OCO4)CC2)=C[C@H](c2ccc(C(F)(F)F)cc2)[C@H]1CCCO
PSA is a commonly used medicinal chemistry metric for the optimization of a drug's ability to permeate cells. Please predict psa of this molecule.