Cc1ccc(-n2c(SCC(=O)Nc3cccc(Cl)c3)nc3[nH]nc(C)c3c2=N)cc1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?