CCc1nnc(NC(=O)CSc2nnc(Cc3cc(O)nc(O)n3)n2-c2ccc(OC)cc2)s1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?