CCCCN=C(S)N(CCN(CC)CC)Cc1cc2cc3c(cc2nc1O)OCCO3
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?