CO[C@@H]1c2cc(F)ccc2/C(=C\CCOC(=O)C/C=C/c2ccccc2)[C@H]1C
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?