Cc1nc(C(C)N(C)Cc2nc(-c3ccc4c(c3)OCO4)no2)c(C)s1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?