COc1ccc(OC)c(C2C(C(C)=O)=C(O)C(=O)N2CCC(=O)O)c1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?