O=C1CN(C(=O)COc2ccc(Cl)cc2)C(c2ccc(F)cc2)c2cc(Br)ccc2N1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?