COC(=O)c1cc(C(=O)Nc2ccc(S(N)(=O)=O)cc2)cc([N+](=O)[O-])c1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?