CC(O)C(=O)O.Cc1ccc(CN(CC(O)COc2cccc3[nH]cc(C)c23)C(C)(C)C)cc1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?