CCc1ccc(NCc2cc3ccc(OC)cc3n(CC(=O)Nc3cccc(Cl)c3C)c2=O)cc1
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?