CCC1CCc2c(sc(NC(=O)CSc3nc(-c4ccco4)cc(C(F)(F)F)n3)c2C#N)C1
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?