COC(=O)C1=C(C)N(Cc2ccccc2)C2=C3C(=O)CCCC3[C@@](O)(C(=O)OC)C(=O)N2C1c1ccccc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?