CCOC(=O)c1c(C)[nH]c(C)c1S(=O)(=O)N(C)CC(=O)NCc1cccc(Br)c1
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?