COc1ccc(CN2C(=O)C(Cc3ccccc3)Nc3ncnc(N4CCOCC4)c32)cc1.O=C(O)C(F)(F)F
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?