COc1ccccc1NS(=O)(=O)c1ccc(C)c(C(=O)NC2CCN(Cc3ccccc3)CC2)c1.Cl
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?