Cc1ncc(CO)c2cc(-c3nnc(Nc4ccc5c(c4)OCO5)s3)c(=O)oc12
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?