COc1ccc(S[C@@H](CCN2CC[C@H](C)CCC2=O)c2ccccc2)cc1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?