COC(=O)C(NC(=O)CCc1c(C)nc2c(c(C)nn2-c2ccccc2)c1C)C(C)C
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?