COC(=O)C1CCN(C(=O)C2CCN(C(=O)[C@@H](NS(=O)(=O)c3ccc(C)cc3)C(C)C)CC2)CC1
Lipinski's rule of five describes molecular properties important for a drug's pharmacokinetics in the human body. How many rules of Lipinski's rule of five does this molecule break?