COc1ccc(OC)c(C2C3=C(O)CCCC3=Nc3c2c(=O)n(C)c(=O)n3C)c1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?