Cc1nc2cc(OCc3cc(C(=O)NC(C)c4cn(C)nc4C)no3)ccc2s1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?