Cc1ccc(Cn2c(C(CO)Nc3nc(-c4ccc(Cl)c([N+](=O)[O-])c4)cs3)nc3ccccc32)cc1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?