O=C(NCc1nnc(SCC(=O)N2CCN(c3ccccc3)CC2)o1)c1c(F)cccc1Cl
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?