COc1ccc(OC)c(CN2CCN(Cc3cc(=O)oc4cc(O)ccc34)CC2)c1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?