Cc1cc(NS(=O)(=O)c2c(C(=O)N3CCOCC3)c(C)n(C)c2C)ccc1Br
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?