COCCN(Cc1cc2cc(C)ccc2n2nnnc12)C(S)=Nc1cccc(C)c1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?