CC(=O)N1CCc2cc(S(=O)(=O)NC(C(=O)NC3CCCc4ccccc43)C(C)C)ccc21
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?