COC(=O)C1=C(C(=O)OC)[C@@H]2N(C)c3ccccc3[C@@]23C[C@@H](CO)N(C(=O)NCCBr)C3=N1
Lipinski's rule of five describes molecular properties important for a drug's pharmacokinetics in the human body. How many rules of Lipinski's rule of five does this molecule break?