COc1ccc(C2=C(C)C(=O)N(Cc3ccc(C(=O)NCc4ccccc4C)cc3)S2(=O)=O)cc1
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?