CC(C)Nc1nnc(SCC(=O)/C=C2\N(C)c3ccccc3C2(C)C)s1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?