CC(C)c1cc(C(C)C)c(S(=O)(=O)N2c3ccccc3[C@@]3(Br)C[C@H]4C(=O)N[C@@H](Cc5ccccc5)C(=O)N4[C@@H]23)c(C(C)C)c1
In analogy to the rule of five, it has been proposed that ideal fragments should follow the rule of three, in which the molecular weight of a fragment is <300, the c LogP is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?