CCc1cc(Cl)c(OC)c(C(=O)NC[C@@H]2CCCN2CC)c1O.Cl
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?