COc1cc(/C=C2\SC(N)=NC2=O)ccc1OCC(=O)Nc1ccc(C)cc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?