Cn1nc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)c2c1-c1ccccc1S(=O)(=O)C2
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?