COc1ccc(C2/C=C\C(c3ccc(OC)cc3)N(Cc3ccc(F)cc3)C(=O)C(=O)N2Cc2ccc(F)cc2)cc1
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?