CCOc1ccc(-c2c(C)nn3c(C)c(C(=O)NCC(C)c4ccccc4)cnc23)cc1OCC
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?