COC(=O)C1=COC(O[C@H]2OC(CO)[C@H](O)C(O)C2O)[C@H]2C1C(=O)C[C@@H]2C
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?