CN(C)CCCN1C(=O)C(O)=C(C(=O)c2ccncc2)C1c1cccc(Br)c1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?