COc1ccc(CCNC(=O)CSc2nc3nc(C)c(Cc4ccc(C)cc4)c(C)n3n2)cc1OC
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?