COc1ccccc1CNC(=O)Cn1c(=O)ccc2cc(S(=O)(=O)N3CCCC3)ccc21
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?