COc1cccc(/C(O)=C/c2nc3ccc(C(=O)NCCc4ccc(Cl)cc4)cc3nc2O)c1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?