COc1cc(OC)cc(C(=O)Nn2cc(C(=O)Nc3c(F)cccc3F)c3ccccc3c2=O)c1
A rotatable bond is defined as any single non-ring bond, attached to a non-terminal, non-hydrogen atom. Amide C-N bonds are not counted because of their high barrier to rotation.  How many rotatable bonds does the molecule have?