CNC(C(=O)c1ccccc1)C(OC(C)=O)c1cccc([N+](=O)[O-])c1.[O-][Cl+3]([O-])([O-])O
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?