Cc1cccc(N(C)S(=O)(=O)c2ccc3ncc(C(=O)N4CCOCC4)c(O)c3c2)c1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?