COCCOc1ccc(C(F)(F)F)cc1NC(=O)CN1C(=O)NC(C)(c2ccc3c(c2)OCO3)C1=O
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?