CC1(C)Cc2c(cnn2-c2cccc(F)c2)C(NC(=O)CCN2CCCC2=O)C1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?