Cc1cc(C)c(C)c(S(=O)(=O)N2CCN(C(=O)c3cc(O)nc4ccccc34)CC2)c1C
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?