Cc1cccc2[nH]c(CN(C)C(=O)C3CCC(=O)N(C4CC4)C3)nc12
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?