CCOc1ccccc1CN1CCNC(=O)C1CC(=O)NCc1cc(C)n(C)n1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?