Cc1[nH]c(C)c(S(=O)(=O)N2CCN(c3ccccc3)CC2)c1C(=O)N1CCCC1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?