COc1cccc(CN2C(=O)N(c3ccc(C)cc3)C(=O)C2CC(=O)Nc2cc(OC)cc(OC)c2)c1
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?