Oc1nc(CSc2ncc(C(F)(F)F)cc2Cl)nc2cc(C(F)(F)F)ccc12
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?