COC(=O)C1=C[C@@H](C(=O)OC)[C@@H]2C3=C(C(=O)[C@@]2(C)NC(=O)c2ccccc2)[C@H](c2ccccc2)[C@@H]2C(=O)NC(=O)[C@@H]2[C@@H]3C1
In analogy to the rule of five, it has been proposed that ideal fragments should follow the rule of three, in which the molecular weight of a fragment is <300, the c LogP is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?