CCn1c(SCC(=O)N(C)Cc2ccc(OC)c(F)c2)nc2cc(S(N)(=O)=O)ccc21
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?