Cc1ccc(CS/C(Nc2ccccc2C)=C(\C#N)C(N)=O)c(C)c1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?