CCOC(=O)COc1ccc(Cl)cc1C1NC(=O)NC(C)=C1C(C)=O
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?