COc1ccccc1S(=O)(=O)NCc1ccc(C(=O)NC(C)c2ccccn2)cc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?