CCc1nnc(NC(=O)CSc2nnc(-c3ccc(S(=O)(=O)N4CCCC4)cc3)n2CC)s1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?