COc1ccc(CCn2c3c(c(=O)[nH]c2=O)C(NC(=O)c2ccccc2)(C(F)(F)F)C(=O)N3)cc1OC
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?