Cc1[nH]c(SCC(=O)Nc2cc(S(C)(=O)=O)ccc2Cl)nc1Cc1ccccc1
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?