CO[C@@H]1CC=C2CCN3CCC4=C(CC(=O)OC4)[C@]23C1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?