COc1cccc(C2c3c(ncn(-c4ccccc4Br)c3=N)Oc3ccc4ccccc4c32)c1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?