COC(=O)c1c(N2C(=O)[C@@H]3[C@@H]4CCCN4[C@@]4(C(=O)Nc5c4ccc(C)c5C)[C@@H]3C2=O)sc(C)c1C
PSA is a commonly used medicinal chemistry metric for the optimization of a drug's ability to permeate cells. Please predict psa of this molecule.