COc1ccc(N2C(=O)CSC23C(=O)N(CC(=O)Nc2ccccc2F)c2ccccc23)cc1
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?