CC(=O)N1CCc2cc(S(=O)(=O)C(C)CC(=O)NCc3ccc(C)o3)ccc21
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?