COc1ccc(OC)c(C2=CC(=O)C[C@H](c3ccc4c(c3)OCO4)C2)c1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?