COc1ccc(C)cc1NC1=C(Cl)C(=O)N(C2CCCCC2)C1=O
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?