Cc1ccc(Cn2c(O)c(N=NC(S)=Nc3ccccc3F)c3cc(S(=O)(=O)N4CCOCC4)ccc32)cc1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?