COc1ccc(C2NC(=O)NC(O)(C(F)(F)F)C2C(=O)c2ccccc2)cc1OC
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?