Cc1cc(O)nc(SCC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)c1C#N
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?