COc1ccc(C[C@H]2CN3C(=NC[C@@H]3Cc3ccc(O)cc3)N2C[C@H](C)NC(=O)c2ccc(C)c(Br)c2)cc1
Lipinski's rule of five describes molecular properties important for a drug's pharmacokinetics in the human body. How many rules of Lipinski's rule of five does this molecule break?