This is a confirmatory assay, called the PUBCHEM_BIOASSAY, designed for screening selective antagonists of the KOR receptor using high-throughput imaging techniques. Additional related assays are also available, including AID1777, AID1778, AID1785, AID1786, AID2284, AID2285, AID2348, AID2352, AID2357, AID2359, AID2370, AID2420, AID2478, AID2491, AID2492, AID2493, AID2495, AID2497, AID2498, AID2500, AID434981, AID449737, AID463105, AID488822, AID488842, and AID488935. This is a direct, single protein target assay, with a confirmatory assay category and functional assay type description, and it uses Homo sapiens as the assay organism. Does this assay show efficacy of the molecule?