The rule of three is a common guideline that is often taken into consideration while developing orally active drugs. The molecular weight of such drugs should be equal to or less than 300, and the c LogP value of the drug should be less than or equal to 3. As per the rule of three, the hydrogen bond donor count of a drug must not exceed three, and the hydrogen bond acceptor count of the drug should also be limited to three or less. This rule helps in ensuring that the drug is efficiently absorbed in the gastrointestinal tract and is able to reach its target site effectively.Is the molecule in accordance with the rule of three?