COc1ccc(OC)c(S(=O)(=O)N2Cc3ccccc3CC2C(=O)Nc2ccc(Cl)cc2)c1
A rotatable bond is defined as any single non-ring bond, attached to a non-terminal, non-hydrogen atom. Amide C-N bonds are not counted because of their high barrier to rotation.  How many rotatable bonds does the molecule have?