COc1ccc(C2/C=C\CN(S(=O)(=O)/C=C/c3ccccc3)CC(=O)N2Cc2ccc(F)cc2)cc1
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?