COc1ccc(C(=O)Cn2c(=O)c(-c3cc(C)ccc3NC(C)=O)nc3ccccc32)cc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?