Cc1cc(C)c2c(=O)c3c(oc2c1)C(=O)N(CCO)C3c1cccc(O)c1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?