CCC1Sc2ccc(S(=O)(=O)CCC(=O)Nc3ccc(NC(C)=O)cc3)cc2NC1=O
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?