COc1cc(/C=C2\N=C(c3ccccc3)OC2=O)ccc1OCc1c(C)no[n+]1[O-]
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?