COc1ccc2oc(C(=O)Nc3ccc(S(=O)(=O)N(C)C4CCN(C)CC4)cc3)c(C)c2c1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?