CC(C)(C)OC(=O)N1CCC(c2c(C(=O)NC3CC3)cnn2-c2ccccc2)CC1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?