Cc1ccc(Cl)cc1Nc1nn2c(=O)c3ccc(C(=O)NCc4ccc(F)cc4)cc3nc2s1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?