Cc1cc2c(cc1S(=O)(=O)NCCc1ccc(Cl)cc1)OCC(=O)N2
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?