COc1ccc(-c2cc(=O)oc3cc(OC(C)C(=O)NC(Cc4c[nH]c5ccc(O)cc45)C(=O)O)ccc23)cc1
Molecules with a polar surface area of greater than 60 angstroms squared (Å2) is hard to pass brain blood barrier. What's the psa of this molecule?