COc1ccc([C@H]2CC(=O)C=C(c3cccc4c3Oc3ccccc3S4)C2)cc1OC
In analogy to the rule of five, it has been proposed that ideal fragments should follow the rule of three, in which the molecular weight of a fragment is <300, the c LogP is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?