CC(=O)Nc1ccc(S(=O)(=O)NCC2CCC(C(=O)NCCN(CC(C)C)CC(C)C)CC2)cc1
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?