COc1ccc(-n2c(=O)c3c4c(sc3n3c(S)nnc23)COC(C(C)C)C4)cc1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?