CCOC(=O)c1c(NC(=O)c2nc(S(C)(=O)=O)ncc2Cl)sc(C(C)=O)c1C
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?