COc1cc2c3c(c1)c(C1=NC(=S)NC1=O)c(O)n3C(C)(C)C=C2C
In analogy to the rule of five, it has been proposed that ideal fragments should follow the rule of three, in which the molecular weight of a fragment is <300, the c LogP is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?