CCOC(=O)c1c(NC(=O)c2nc(S(C)(=O)=O)ncc2Cl)sc(C(C)=O)c1C
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?