COc1ccc(CCN2CCC(CNC(=O)c3cnn(-c4ccc(C)cc4)c3C3CCN(C(=O)OC(C)(C)C)CC3)CC2)cc1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?