CCN1c2ccccc2-n2cccc2C12CCN(C(=O)Nc1ccccc1C(F)(F)F)CC2
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?