C=CCn1c(=O)c2ccccc2n2c(SCC(=O)Nc3sc(C)c(CC)c3C(=O)OCC)nnc12
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?