Cc1ccnc(NC(=O)CCC(=O)N(Cc2ccco2)C(C(=O)NC(C)C)c2ccc(F)cc2)c1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?