COC(=O)c1ccc(COc2cc(O)c3c(c2)OC(C)(C)CC3=O)cc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?