O=C1Nc2c(c(=O)[nH]c(=O)n2-c2ccc(F)cc2)C1(NS(=O)(=O)c1ccccc1)C(F)(F)F
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?