Cc1nnc(-n2nc(C)c(SCC(=O)Nc3ccc(F)cc3)c2C)nc1O
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?