Cc1cc(OCC(=O)N2CCC(O)(c3ccc(Cl)cc3)CC2)c2c(C)cc(=O)oc2c1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?