CCN1CCCC1CN(Cc1cc2ccc(C)cc2nc1O)C(S)=Nc1ccccc1C(=O)OC
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?