CCCCOC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c1cc(OC)ccc1OC)c1ccccc12
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?