COc1ccc(-c2noc(CN(C)S(=O)(=O)c3c(C)cc(C)cc3C)n2)cc1OC
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?