Cc1cc(C)c2c(N)c(C(=O)NN3CC(=O)N(c4ccccc4)CC3=O)sc2n1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?