Cc1c(Cl)cccc1N=C(S)N1CC2CC(C1)c1cccc(=O)n1C2
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?