COC(=O)C1=CO[C@@H](C)[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12.Cl
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?