COc1ccc([C@H]2/C=C\CN(S(=O)(=O)c3ccc4ccccc4c3)[C@@H](C)C(=O)N2Cc2ccc(F)cc2)cc1
Lipinski's rule of five describes molecular properties important for a drug's pharmacokinetics in the human body. How many rules of Lipinski's rule of five does this molecule break?