COc1ccc([C@]23Cc4ccccc4[C@H](O2)c2c(c4ccc(OC)cc4oc2=O)O3)cc1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?