CNC(=O)CC1C(=O)N(c2ccc(OC)cc2)C(=S)N1NC(=O)c1cccc(F)c1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?