CCc1n[nH]c(C(=O)N2CCCC(C(=O)c3cccc(C(F)(F)F)c3)C2)c1C
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?