CCOC(=O)c1c(NC(=O)CN2C(=O)NC(C)(c3ccc(Cl)cc3)C2=O)sc(C(=O)NC)c1C
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?