COc1ccc([C@H]2CC(=O)C=C(c3cc(Cl)cc(Cl)c3)C2)cc1
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?