COc1ccc(NC(=O)C(C)n2c(C)c3cnn(-c4ccccc4)c(=O)c3c2C)cc1Cl
The rule of three is typically followed by orally active drugs, which have a molecular weight of <300, a c LogP of ≤3, a hydrogen bond donor count of ≤3 and a hydrogen bond acceptor count of ≤3. Does the molecule comply with the rule of three?