CCc1nnc(NC(=O)CCC(=O)N2CCN(Cc3ccc(OC)c(F)c3)CC2)s1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?