Cn1c(SCc2nc(O)c3ccc(C(=O)O)cc3n2)nnc1C(F)(F)F
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?