COc1ccc(S(=O)(=O)N2CCC(NC(=O)C(Cc3cccc(OC)c3OC)NC(C)=O)CC2)cc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?