COc1ccc(CCNC(=O)C2CC(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)=NO2)cc1
An acid's negative base-10 logarithmic dissociation constant (pka) follows directly from its underlying thermodynamics; pKa is directly proportional to its standard Gibbs free energy change. What is the pka value of this molecule?