Fc1ccc2[nH]c3c(c2c1)CN(C(S)=NCc1ccccc1)CC3
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?