O=C1[C@H]2CCCC[C@H]2C(=O)N1c1nnc(Cc2ccc(F)cc2)[nH]1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?