CC1CC(C)CN(c2cc(=O)n(Cc3ccc(F)cc3)c(=O)[nH]2)C1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?