COc1ccc(CCNCC(=O)Nc2ccc(C(=O)N3CCCCC3)cc2)cc1.O=C(O)C(=O)O
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?