COc1c(O)c2c(=O)cc(OC)c3c4c(OC)cc(O)c5c(=O)c(OC)c6c(c(c1[C@H](C(C)=O)[C@](C)(O)C6)c23)c54
Lipinski's rule of five describes molecular properties important for a drug's pharmacokinetics in the human body. How many rules of Lipinski's rule of five does this molecule break?