CCc1cc(=O)oc2cc(OC(C)C(=O)NCC(O)c3ccccc3)c(Cl)cc12
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?