O=C1C2C3C=CC(c4ccccc4)(C2C(=O)N1c1cccc(Cl)c1)C1C(=O)N(c2cccc(Cl)c2)C(=O)C31
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?