COc1ccc([C@H]2[C@H](C(=O)OC(C)(C)C)N3N=Cc4ccccc4C3C23C(=O)c2ccccc2C3=O)cc1OC
Molecules with a polar surface area of greater than 60 angstroms squared (Å2) is hard to pass brain blood barrier. What's the psa of this molecule?