CCOC(=O)c1c(NC(=S)NC(=O)c2cnn(CC)c2)sc2c1CCC(C)C2
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?