COC(=O)c1ccc(C2C(C#N)=C(N)Oc3cc(O)ccc32)cc1
An acid's negative base-10 logarithmic dissociation constant (pKa) follows directly from its underlying thermodynamics; the negative pKa is directly proportional to its standard Gibbs free energy change. What is the negative pKa value of this molecule?