COc1cccc(NC(=O)Nc2cc(C(=O)NC(C)C)ccc2N2CC3CC(C2)c2cccc(=O)n2C3)c1
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?