CCOC(=O)C1=C(CS(=O)(=O)c2ccc(F)cc2)NC(=O)NC1c1ccc(O)c(O)c1
The negative base-10 logarithmic of dissociation constant (pka) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the pka value of this molecule?