COc1ccc2c(c1)OC[C@H]1[C@H]2N2C(=O)CN(Cc3ccco3)C(=O)[C@@]2(C)[C@H]1c1ccccc1
Molecules with a polar surface area of greater than 140 angstroms squared (Å2) tend to be poor at permeating cell membranes. What's the psa of this molecule?