COC(=O)C1=C(C(=O)OC)[C@@H]2N(C)c3ccc(OC)cc3[C@@]23C[C@@H](C(=O)OC)N(S(=O)(=O)c2ccc(Br)cc2)C3=N1
Heavy atom refers to any atom that is not hydrogen. The heavy atoms in molecules are carbon, oxygen, nitrogen, and sulfur. How many heavy atoms are in the molecule?