CCOC(=O)C1(Cc2ccc(Cl)cc2)CCN(C(=O)C2=NNC(=O)CC2)CC1
The negative base-10 logarithmic of dissociation constant (pKa) for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction; the negative pKa value is directly proportional to the standard Gibbs free energy change for the reaction. What is the negative pKa value of this molecule?