O=C1[C@H]2[C@@H](C(=O)N1C1CCCCC1)[C@@H](c1ccc(F)cc1)N1C(=O)N(c3ccc(C(F)(F)F)cc3)C(=O)[C@@]21Cc1ccccc1
Orally active drug usually follows the rule of three, in which the molecular weight of a fragment is <300, the c Log P is ≤3, the number of hydrogen bond donors is ≤3 and the number of hydrogen bond acceptors is ≤3. The molecule meets rule of three or not?