Based on epidemiological data, we know that one of the causes, or one of the associations, I should say, is advanced paternal age, that is, increasing age of the father at the time of conception.
根据流行病学数据， 我们知道，诱因之一， 或者说，关联因素之一， 是较高的父亲年龄， 也就是说，在受孕时间 父方的年龄较高。