And it's important, if you try to model this, you can think about normal development as a loss of cortical mass, loss of cortical gray matter, and what's happening in schizophrenia is that you overshoot that mark, and at some point, when you overshoot, you cross a threshold, and it's that threshold where we say, this is a person who has this disease, because they have the behavioral symptoms of hallucinations and delusions.
这些非常重要，如果通过建模进行量化， 你可以理解在正常发育中 大脑皮层质量是会减少，或是灰质轻微损失， 但精神分裂症患者的这些损失量超标， 在某些时候， 正是超过这个标准值， 我们说这个人患有精神分裂症， 此时他的行为异常，多数呈现出 幻觉和妄想，