So these are patients who had received surgery, high dose radiation to the head and first-line chemotherapy, and that had failed and their tumors had grown back.
つまりこれらの患者は すでに手術を受けて大量の放射線も頭部に受け 初回化学療法を受けたが 効果がなく 再び腫瘍が増殖してしまった人たちです