translation.en: Well, there's a multitude of factors at play, but I think one of the key factors is that the tools that we currently have available to test whether a drug is going to work, whether it has efficacy, or whether it's going to be safe before we get it into human clinical trials, are failing us. They're not predicting what's going to happen in humans.
translation.zh: 好，这里有一系列影响因素， 但我认为主因之一是 我们目前的工具， 测试新药是否可用， 是否有疗效， 是否是安全的药品， 在开展人体临床试验之前， 这些工具都无法满足我们的要求。这些工具 不能预测药物将对人体产生何种作用。