translation.en: Let's take them all, and let's pull them back a little bit by those that are known to have severe symptoms, where the parents, the child, those around them would know that they'd gotten sick, and let's go ahead and then frame them again by those parts of the genes where we know that there is a particular alteration that is known to be highly penetrant to cause that disease.
translation.zh: 让我们看着所有的人，让 我们把它们范围缩小一点点 用那些 父母，孩子有着已知的严重的症状的病来说， 那些周围的人都知道 他们会生病， 让我们继续并且给他们再次定位 用我们已经知道的某些部分的基因 那些有着特别改变而 总所周知是引起 那种疾病的高度相关的基因。