That is a ridiculous statement.  How about paying taxes, obeying fire codes & municipal ordinances, paying employees properly, etc.?  How about age discrimination?  You want your grandma denied service or a job because she is too old?  

Colorado law says a public business can't discriminate due to sexual orientation or gender identity.  End of story.

If this puritanical jerk doesn't like it, he can move his business to Wyoming, Texas, Alabama or a similar backward state where he can be a homophobe without any worry.