This is going to sound harsh but I'm OK with the anti-vaxxers. Darwinism will kick in,  the herd will be culled of the weakest which in this case is intellectually.  Naturally deselection of the weak is the way to go.
I am also not in favour of treating them if they contract any preventable diseases and forced quarantines if necessary.
They have to right to risk their own lives but not others.