What is Quetiapine?
{{Infobox drug | Watchedfields = changed | verifiedrevid = 443404910 | drug_name = | type = | IUPAC_name = 2-(2-(4-Dibenzo[''b'',''f''][1,4]thiazepine-11-yl-1-piperazinyl)ethoxy)ethanol | image = Quetiapine.svg | width = 250px | alt = | caption = | image2 = Quetiapine-from-xtal-3D-balls.png | width2 = 225px <!--Clinical data--> | pronounce = {{IPAc-en|k|w|ᵻ|ˈ|t|aɪ|.|ə|p|iː|n}} {{respell|kwi|TY|ə-peen}} | tradename = Seroquel, Temprolide, others | Drugs.com = {{drugs.com|monograph|quetiapine-fumarate}} | MedlinePlus = a698019 | licence_EU = | licence_US = Quetiapine | pregnancy_AU = B3 | pregnancy_US = C | pregnancy_category = | legal_AU = S4 | legal_CA = Rx-only | legal_US = Rx-only | legal_UK = POM | legal_status = | routes_of_administration = [[Oral administration|By mouth]] <!--Pharmacokinetic data--> | bioavailability = 100%<ref name = Medscape /> | metabolism = [[Liver]] via CYP3A4-catalysed sulfoxidation to its active metabolite norquetiapine (N-desalkylquetiapine)<ref name = GG>{{cite book|last1=Brunton|first1=L|last2=Chabner|first2=B|last3=Knollman|first3=B|title=Goodman and Gilman's The Pharmacological Basis of Therapeutics|edition=12th|publisher=McGraw Hill Professional|year=2010|isbn=978-0071624428|url=https://books.google.com/books?id=bVUfAQAAQBAJ}}</ref> | protein_bound = 83%<ref name=EMC>{{cite web|title=Quetiapine 25 mg film-coated tablets - Summary of Product Characteristics|date=January 2013|accessdate=20 October 2013|website=electronic Medicines Compendium|publisher=Sandoz|url=http://www.medicines.org.uk/emc/medicine/26575/SPC/Quetiapine+25+mg+film-coated+tablets/|url-status=dead|archiveurl=https://web.archive.org/web/20131020062812/http://www.medicines.org.uk/emc/medicine/26575/SPC/Quetiapine+25+mg+film-coated+tablets/|archivedate=20 October 2013|df=dmy-all}}</ref> | elimination_half-life = 7 hours (parent compound); 9–12 hours (active metabolite, norquetiapine)<ref name = EMC/><ref name = DD>Truven Health Analytics, Inc. DrugPoint System (Internet) [cited 2013 Sep 18]. Greenwood Village