What is Cri du chat syndrome?
{{Infobox medical condition (new)|name=Cri du chat, or Cri-du-chat|diagnosis=|deaths=|frequency=|prognosis=|medication=|treatment=|prevention=|differential=|risks=|field=[[Medical genetics]]|causes=|types=|duration=|onset=|complications=|synonyms={{bulleted list|Chromosome 5p deletion syndrome|5p− syndrome|Lejeune's syndrome}}|caption=Facial features of a person with Cri du chat syndrome at the age of 8 months (A), 2 years (B), <br />4 years (C) and 9 years (D)|image=Criduchat.jpg|alt=}} '''Cri du chat syndrome''' (Cat's cry syndrome) is a [[medical condition]] that affects about 1 in 50,000 infants. Infants with this illness have a difference. When they cry it sounds like a cat meowing or sometimes like a cat screaming. As the child gets older, this doesn't happen so much. Cri du chat syndrome was first written about by [[Jerôme Lejeune]], a French [[pediatrician]] in 1963, so it is sometimes called '''Lejeune syndrome'''. The syndrome is caused by a bad copying of a [[gene]], which leaves part of [[chromosome]] 5p missing about 90% of its material. The condition affects more girls than boys: of six cases on average about one is a boy. What is the effect? The name gives a clue. Children who have it have problems with the [[larynx|voice box]]. They usually have other disabilities as well: some have a [[learning disability]] or [[physical disability]], and others have both of these. The following symptoms are common: * The [[head]] and [[skull]] are smaller than they would normally be. * Low muscle tone, meaning that children may have problems feeding, swallowing and sucking. * Teeth can be out of place, too close together or too far apart. * Growth issues: even as adults, people with this syndrome are smaller than normal. * Very poor motor skills, causing difficulty with movement, walking, holding eating utensils. * The child's body will develop later than those of children without the condition. * Ears and face often look different. * A cognitive impairment / intellectual disability Some of these pro