What is Aspirin?
{{Infobox drug | drug_name = | type = | IUPAC_name = 2-Acetoxybenzoic acid | image = Aspirin-skeletal.svg | width = 100px | alt = | caption = | image2 = Aspirin-B-3D-balls.png | width2 = 125px <!--Clinical data--> | pronounce = acetylsalicylic acid {{IPAc-en|ə|ˌ|s|iː|t|əl|ˌ|s|æ|l|ᵻ|ˈ|s|ɪ|l|ᵻ|k}} | tradename = [[Bayer#Aspirin|Bayer Aspirin]], many others | Drugs.com = {{drugs.com|monograph|aspirin}} | MedlinePlus = a682878 | licence_EU = yes | licence_US = Aspirin | pregnancy_AU = C | pregnancy_US = C | pregnancy_US_comment = D in the 3rd trimester | pregnancy_category = | legal_AU = S2 | legal_AU_comment = except when given intravenously (in which case it is schedule 4), used in animal medicine (schedule 5/6) or when the dose is higher than usual. | legal_UK = GSL | legal_US = OTC | legal_status = | routes_of_administration = by mouth, rectal, lysine acetylsalicylate may be given [[intravenous therapy|intravenously]] or [[intramuscular injection|intramuscularly]] <!--Pharmacokinetic data--> | bioavailability = 80–100%<ref name=MSR>{{cite web|title=Zorprin, Bayer Buffered Aspirin (aspirin) dosing, indications, interactions, adverse effects, and more|work=Medscape Reference|publisher=WebMD|access-date=3 April 2014|url=http://reference.medscape.com/drug/zorprin-bayer-buffered-aspirin-343279#showall|url-status=live|archive-url=https://web.archive.org/web/20140407080151/http://reference.medscape.com/drug/zorprin-bayer-buffered-aspirin-343279#showall|archive-date=7 April 2014|df=dmy-all}}</ref> | protein_bound = 80–90%<ref name = MD>{{cite web|title=Aspirin|work=Martindale: The Complete Drug Reference|publisher=Pharmaceutical Press|date=14 January 2014|access-date=3 April 2014|url=http://www.medicinescomplete.com/mc/martindale/current/2601-s.htm|editor=Brayfield, A}}</ref> | metabolism = [[Liver]], ([[CYP2C19]] and possibly [[CYP3A]]), some is also hydrolysed to salicylate in the gut wall.<ref name = MD/> | elimination_half-life = Dose-dependent; 2 h to 3 h for low doses (100 mg or less), 15 h to 30 h for large doses