What is Molecular subtypes?
{{one source|date=July 2022}} '''Molecular subtyping''' of [[cancer]], as its name suggests, is a new way to classify cancers into different groups based on [[Molecule|molecular]] data and classification models. Unlike the traditional [[Histology|histological]] classification of cancer, molecular classifications rely on [[Biomarker|biomarkers]] and classifiers. Biomarkers can be [[Gene|genes]], [[microRNAs]] (miRNAs), [[DNA methylation]] markers and others. [[Classifier]]s can be built by [[machine learning]] algorithms, such as [[Prediction Analysis for Microarrays]] (PAM), [[Support Vector Machines]] (SVMs) and more.<ref>{{cite journal |last1=Zhao |first1=L |last2=Lee |first2=VHF |last3=Ng |first3=MK |last4=Yan |first4=H |last5=Bijlsma |first5=MF |title=Molecular subtyping of cancer: current status and moving toward clinical applications. |journal=Briefings in Bioinformatics |date=25 March 2019 |volume=20 |issue=2 |pages=572–584 |doi=10.1093/bib/bby026 |pmid=29659698 |url=https://doi.org/10.1093/bib/bby026 |accessdate=14 July 2022}}</ref> Biomarkers can be informative genes. ==References== {{reflist}} [[Category:Cancer]] {{med-stub}}