Just three things.

First of, the only reason this should ever be compared to 2001: A Space Odyssey is to show how superior 2001 is.

Difference in approach Kubrick: Powerful and visceral imagery, almost no dialogue.

Nolan: Blah blah blah blah blah blah. Everyone is talking, everything has to be spelled out and explained.

Second, too much focus on the wrong things i.e. How Black Holes work, hint they don't work like that. It's about as scientifically accurate as Star Wars or Armageddon.

And third, no amount of Matthew McConaughey crying and sappy sentimentality can make up for poor filmmaking.