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  A calcium channel blocker, diltiazem works by preventing calcium from building up in blood vessels, which makes it easier for blood to flow, thereby lowering blood pressure. Useful in the treatment of cardiac arrhythmias, hypertrophic cardiomyopathy, or just lowering high blood pressure (although other drugs are more effective at lowering blood pressure), diltiazem is one of the most prescribed drugs for the treatment of heart disease. Although originally designed for use in people, it can legally be prescribed as an ‘extra-label’ drug for pets by your vet.
  Pets with severe hypotension, sick sinus syndrome, 2nd or 3rd degree AV block, acute myocardial infarction, or pulmonary congestion should not take diltiazem. Elderly pets, pets taking beta blockers, or pets with liver or kidney failure should take diltiazem with caution. Due to the potential teratogenic qualities of diltiazem, it should only be given to pregnant pets if the benefits outweigh the risks to the baby.
  Pets taking diltiazem with cyclosporine, digoxin, or quinidine should be monitored closely, as the levels of diltiazem may be affected. Cimetidine and ranitidine might cause an increase in the plasma levels of diltiazem. Diltiazem might increase the bioavailability of propranolol.
  Dog -- 0.125 - 0.35 mg/kg IV or 0.5 - 1.5 mg/kg orally, every 8 hours Cat -- 0.125 - 0.35 mg/kg IV or 7.5 mg orally every 8-12 hours
  The most common side effect of diltiazem is bradycardia, but other side effects, such as vomiting, diarrhea, depression, and loss of appetite, are possible. Hypotension, heart block, arrhythmias, central nervous system effects, and elevated liver enzymes are also possible, but rare.
  Learn about preventing and treating heart disease in your cat or dog here.
  Canine heart disease is a serious problem, but one that can be dealt with if detected early enough. The treatment and management of this condition might require some substantial changes to the way you live with your dog.
  Clopidogrel bisulfate is the generic equivalent of the popular anticoagulant, Plavix, and is used to help prevent thrombosis in cats and chronic hypercoagulation in dogs. Learn more about how this generic of Plavix for dogs can help your pet.
  Amlodipine Besylate is a calcium channel blocker that protects muscles from calcium deposits forming, allowing blood vessels to relax. Helping to lower blood pressure in cases of hypertension, amlodipine besylate can help keep your pet healthy. Learn more about amlodipine besylate here.
  Enter your e-mail address to get a secret discount
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explanation: The document provides information about the drug diltiazem, including its mechanism of action, uses, contraindications, dosages for dogs and cats, potential side effects, and interactions with other drugs. It also briefly mentions other drugs like clopidogrel bisulfate and amlodipine besylate. The text does not contain a math question or an answer to a math question.
distilabel_metadata.content: Evaluate the user given text extract and determine if it contains a math question and optionally and answer to this question.
  
  Output rules:
  
  1. Briefly describe the document and mention if it contains a question or a question and answer.
  2. Finalize the output with: Label: no-question,question,question-and-answer,multiple-question,multiple-question-and-answer
distilabel_metadata.role: system
distilabel_metadata.content: or Sign in using Facebook
  or Sign up using Facebook
  $1 Spent = 1 point Earned Get Double Points on Prescriptions
  Earn points with every dollar you spend to redeem for discounts
  Get personal recommendations & stay informed about what's best for your pet's health
  A calcium channel blocker, diltiazem works by preventing calcium from building up in blood vessels, which makes it easier for blood to flow, thereby lowering blood pressure. Useful in the treatment of cardiac arrhythmias, hypertrophic cardiomyopathy, or just lowering high blood pressure (although other drugs are more effective at lowering blood pressure), diltiazem is one of the most prescribed drugs for the treatment of heart disease. Although originally designed for use in people, it can legally be prescribed as an ‘extra-label’ drug for pets by your vet.
  Pets with severe hypotension, sick sinus syndrome, 2nd or 3rd degree AV block, acute myocardial infarction, or pulmonary congestion should not take diltiazem. Elderly pets, pets taking beta blockers, or pets with liver or kidney failure should take diltiazem with caution. Due to the potential teratogenic qualities of diltiazem, it should only be given to pregnant pets if the benefits outweigh the risks to the baby.
  Pets taking diltiazem with cyclosporine, digoxin, or quinidine should be monitored closely, as the levels of diltiazem may be affected. Cimetidine and ranitidine might cause an increase in the plasma levels of diltiazem. Diltiazem might increase the bioavailability of propranolol.
  Dog -- 0.125 - 0.35 mg/kg IV or 0.5 - 1.5 mg/kg orally, every 8 hours Cat -- 0.125 - 0.35 mg/kg IV or 7.5 mg orally every 8-12 hours
  The most common side effect of diltiazem is bradycardia, but other side effects, such as vomiting, diarrhea, depression, and loss of appetite, are possible. Hypotension, heart block, arrhythmias, central nervous system effects, and elevated liver enzymes are also possible, but rare.
  Learn about preventing and treating heart disease in your cat or dog here.
  Canine heart disease is a serious problem, but one that can be dealt with if detected early enough. The treatment and management of this condition might require some substantial changes to the way you live with your dog.
  Clopidogrel bisulfate is the generic equivalent of the popular anticoagulant, Plavix, and is used to help prevent thrombosis in cats and chronic hypercoagulation in dogs. Learn more about how this generic of Plavix for dogs can help your pet.
  Amlodipine Besylate is a calcium channel blocker that protects muscles from calcium deposits forming, allowing blood vessels to relax. Helping to lower blood pressure in cases of hypertension, amlodipine besylate can help keep your pet healthy. Learn more about amlodipine besylate here.
  Enter your e-mail address to get a secret discount
  code for your first purchase:
distilabel_metadata.role: user
distilabel_metadata.raw_output_q_a_detector_0: The document provides information about the drug diltiazem, including its mechanism of action, uses, contraindications, dosages for dogs and cats, potential side effects, and interactions with other drugs. It also briefly mentions other drugs like clopidogrel bisulfate and amlodipine besylate. The text does not contain a math question or an answer to a math question.
  
  Label: no-question