text: Flavors and fragrances
  Flavors and fragrances traditionally depend on essential oils drawn from naturally occurring substances, such as camphor oil, obtained by steaming the wood of the camphor tree, or saffron from the flower of the Crocus sativa. As such, they are often subject to supply and demand and affected by weather and other natural events.
  Synthetic substitutes have been developed for many flavors and fragrances that retain the same odor and flavor characteristics as the natural compound. Cresset software assists in the design, discovery and optimization process by giving you insight into the biological activity of compounds. Our software helps you predict the impact of structural changes on fragrance, flavor, and off-target activity.
  Your starting point may be an existing natural or synthetic compound, or a taste or odor receptor. Our software analyzes the 3D physico-chemical properties of molecules resulting in a quantitative representation of way a compound will interact at a target site.
  The following structures are different versions of the chiral drug Galaxolide, a polycyclic synthetic musk, analyzed in Torch. The field patterns show a marked similarity between the two chiral forms with a weak musk odor (top) and the two forms with a strong musk odor (below).
  Ref: G. Frater, U. Mueller & P. Kraft, Helv. Chim. Acta, 82(10), 1656-1665 (1999).
  Galaxolide® is a registered trademark of International Flavors & Fragrances.
  Structures and odour data from Leffingwell.
explanation: The document discusses the use of natural and synthetic compounds in flavors and fragrances, including the role of essential oils and the development of synthetic substitutes. It also mentions the use of Cresset software in the design and optimization of these compounds, providing insights into their biological activity and interaction with target sites. The document includes an example of the chiral drug Galaxolide and its different forms with varying musk odors.
distilabel_metadata.content: Evaluate the user given text extract and determine if it contains a math question and optionally and answer to this question.
  
  Output rules:
  
  1. Briefly describe the document and mention if it contains a question or a question and answer.
  2. Finalize the output with: Label: no-question,question,question-and-answer,multiple-question,multiple-question-and-answer
distilabel_metadata.role: system
distilabel_metadata.content: Flavors and fragrances
  Flavors and fragrances traditionally depend on essential oils drawn from naturally occurring substances, such as camphor oil, obtained by steaming the wood of the camphor tree, or saffron from the flower of the Crocus sativa. As such, they are often subject to supply and demand and affected by weather and other natural events.
  Synthetic substitutes have been developed for many flavors and fragrances that retain the same odor and flavor characteristics as the natural compound. Cresset software assists in the design, discovery and optimization process by giving you insight into the biological activity of compounds. Our software helps you predict the impact of structural changes on fragrance, flavor, and off-target activity.
  Your starting point may be an existing natural or synthetic compound, or a taste or odor receptor. Our software analyzes the 3D physico-chemical properties of molecules resulting in a quantitative representation of way a compound will interact at a target site.
  The following structures are different versions of the chiral drug Galaxolide, a polycyclic synthetic musk, analyzed in Torch. The field patterns show a marked similarity between the two chiral forms with a weak musk odor (top) and the two forms with a strong musk odor (below).
  Ref: G. Frater, U. Mueller & P. Kraft, Helv. Chim. Acta, 82(10), 1656-1665 (1999).
  Galaxolide® is a registered trademark of International Flavors & Fragrances.
  Structures and odour data from Leffingwell.
distilabel_metadata.role: user
distilabel_metadata.raw_output_q_a_detector_0: The document discusses the use of natural and synthetic compounds in flavors and fragrances, including the role of essential oils and the development of synthetic substitutes. It also mentions the use of Cresset software in the design and optimization of these compounds, providing insights into their biological activity and interaction with target sites. The document includes an example of the chiral drug Galaxolide and its different forms with varying musk odors.
  
  Label: no-question