Creativity stimulates innovation (Wolfe, 2007); it thus plays an important role in economic development in a digital age. The arts and culture community, master of creative practice, is a key component in entrepreneurial ecosystems (EEs). In a context where the digital transition of communities depends on sectoral transversality (Caron et al., 2020), we are analyzing the contributions of the arts and culture community in the development of EEs. Through a case study based on the evolution of a creative hub project, we will specify the dynamics at work in the intersectoral structuring of EEs. In doing so, we will focus our attention on notions of open innovation, creativity and co-development in the digital era.