This article presents individual and collective career guidance practices towards people suffering from chronic disease, who are looking for coming back to work. It takes part of an action-research about what can help or restrain this coming-back. After having presented our theoretical anchors and the methodology we used, we will describe how collective practices issued from an exchange device, and individual ones complement each other to allow people to find in the sight of the others individual strategies and new possibilities. The group dynamics plays an important part in the elaboration of the project, as a support to career transition. Personal interview is focused on telling activities to point out self perception and experienced capabilities. When the illness leads to adjust life course, capacities and desires, one can build a project by experimenting new activities undertaken since the disease has appeared. It provides the opportunity to compare wishes and possibilities.