After an upward suicide trend over the 1990s, recent observations suggest that the rate of suicide is currently declining in the province of Quebec. The present study assesses whether or not significant changes occurred in suicide over the period 1981-2005 according to age group, sex and geography. We used Joinpoint regression model to test time trends in suicide rates. Our results confirm that suicide rates changed significantly towards the end of the 1990s. Since then, suicide rates have been declining in Quebec, more rapidly in men, especially amongst males aged 15-34. The recent decline was more significant in the Montreal census metropolitan area while no important change was noticed for rural and small town area. Further examinations are recommended to identify factors associated with the decline.