Is it possible to overcome the opposition between a radical constructivism and a naive dogmatism -- as it has recently been reformulated, notably by Quentin Meilassoux, in terms of the opposition between correlationism and realism? This article proposes the idea of an original mediation which is not that of human thought. According to Meilassoux the mediation of being can only be embodied in individuals. By questioning this idea, this text tries to think a material and embodied mediation which manifests itself in a particular way in the technique. The reflection on the digital, the editorialization and the digital Humanities becomes the pivot to think a "prehuman" mediation, which allows moreover to solve the problem of the ancestral ones that was at the foundation of Meillassoux's analyses.