How can we better understand the contribution of early-life separations, relationship troubles, and mental health problems in the lives of suicidal individuals? Although depression is a variable that partially explains suicidal behavior, it seems that the life path of those who have died as a result of suicide creates an accumulation of suffering, losses and abandons that work together at a specific moment in one’s life path and generate within such persons an inability to be resilient to other losses. Which experiences have a major impact? How can these experiences have a hold, either positive or negative, during the course of one’s life? The challenge consists of identifying the combinations of events that place individuals at psycopathological risks and, ultimately, lead them to commit suicide. It is well understood that within this chain of interactions, relationships of attachment and family history are crucial and represent the albeit protective and unfortunate beginning of a vicious circle.