This study presents the results of the standardization of the Test of Silent Reading Efficiency and Comprehension (TOSREC) among French sixth graders from Quebec and the results of the TOSREC-FR validation process. The TOSREC-FR for Grade 6 is a screening tool that can be administered in three minutes to an entire class to assess students’ reading comprehension skills three times during the school year. The TOSREC-FR for grade 6 was standardized in thirteen classes in the province of Quebec during the 2018–2019 and 2019–2020 school years. Each raw score is associated with a standardized percentile rank to determine whether the student is below the reading standard compared to students of the same age. The results show that 64% of students who fall below the 25th percentile on one of the TOSREC-FR forms fail the sixth-grade ministerial exam while 76% are classified in difficulty by teachers at the end of the year. The TOSREC-FR’ standardization allows to situate students according to their level of reading skills and to identify students at risk of presenting academic difficulties in reading.