In the age of globalization, means of access to information are undergoing a radical transformation be it in a learning environment or in the use of knowledge. Information management is all the more complex since it goes hand in hand with time-management which seems to be accelerated due to, on the one hand, multi-relations between systems and individuals and on the other hand, the growing urgency for speed in treating cost issues in business management. In this globalized, shifting, multicultural and multilingual universe, research in the field of translation studies appears to be an area in which propositions of solutions to aid those involved in this ever-changing universe can be elaborated. Knowledge management in different cultural universes is a long-standing research activity in the realm of translation studies. For the past few years, classic terminology has resulted in interesting developments regarding databases. On the same note, linguistics and particularly semantics have been key domains of research for knowledge databases and integrated semantic maps. As for the sciences of new technologies and, in particular, research carried out on information systems, career-oriented multimedia knowledge databases have been developed. It is in this light that this research and its possible interaction with ISIT’s research centre, CRATIL, put in place multidisciplinary research projects in which terminology related to specific careers and new technology have become tools of innovation in helping a multilingual and multicultural society.