Even though until the 1980s it was considered to be exclusive to professions related to health and relational care, today it is thought that burn-out can impact all workers, no matter their function or productive activity. How do we measure the important repercussions of this pathology today? This article has two main objectives. First, initiating from research of three of the principal models of measurement — Maslach and Jackson’s model, Siegrist’s model and Karasek’s model — it becomes essential to focus upon how the psychosocial factors which are used to determine burn-out and its prevalence, far from representing fundamental psychological needs, are rather the reflection of the injunctions and constraints characterized by the contemporary work experience. Secondly, considering that these psychosocial factors are not the sole province of the individual, the article will attempt to demonstrate that the practical interventions with “at risk” or “within” burn-out subjects are, for the most part, held at the perimeter of the psychology and responsibility of the individual.