Since 2011, an upsurge in evidence has been documenting the needs and issues of young people and children who feel different in their gender. If it turns out that they are still among the young people most at risk of suicide, peer violence, school failure, depression, anxiety and eating disorders, the living environment (accepting and supporting) seems the most determining factor for their psychic, relational and somatic health and their social and professional integration. To promote harmonious development for trans and questioning young people, an anti-oppressive perspective is needed today.