Couples affected by Alzheimer’s disease face special challenges and need support. The literature shows that interventions aimed at dyads offer interesting and more lasting perspectives. However, there is little research on art therapy. Artistic expression can mediate the martial relationship affected by the illness. The results of this research-intervention carried out with five of these couples reveal that the psychosocial intervention in art therapy studied has enabled couples to experience greater acceptance of their situation, development of their empathy and the possibility of connecting again.