This article aims at presenting the validity of the French version of the Teacher Responsibility Scale, which was developed by Lauermann and Karabenick (2013). In a first study, we administered the French version of the Teacher Responsibility Scale, a scale measuring teachers’ self-efficacy, and a scale controlling for social desirability, to 154 trainee teachers. In a second study, we tested the scale invariance between men and women, between new and experienced teachers, and between a paper and pencil version and an online version in a sample of 533 teachers, using multi-group confirmatory factor analyses. Results indicate that the scale has good psychometric properties and could be used for research and education.