Social workers active in a hospital setting may be called upon to work, during the course of their care trajectory, with persons who are suffering from renal failure and are eligible for a living kidney donation, as well as with their loved ones. In 2019, in order to develop social work interventions in this healthcare speciality, the “Comité de travailleuses sociales en don vivant de rein au Québec” (Committee of Québec social workers in living kidney donations) was established. This committee put together a discussion group for the potential recipients and their loved ones, to support them in identifying a living donor. A social functioning assessment was also developed to identify protective and risk factors for the living donor. The purpose of this article, therefore, is to present the contribution of social workers in the field of living kidney donation in Québec.