There is a growing interest in making better use of research-based evidences to improve psychosocial services for youth and families in difficulty. However, little is known about the best strategies to support the use of research-based evidences by practitioners and managers in this field. Based on a critical review of the literature and a qualitative research, the goal of this study is to describe the needs, in regard to research-based evidences, of 15 practitioners and 15 managers working in a youth center. The study suggests that the production of research-based evidences adapted to practitioners’ and managers’ needs, presented in an adequate format and following the standards of scientific validity, is essential in order to support their use.