This text is an analysis of interactional dynamics during biographical interviews with youth with disabilities. This relationship with the other in its radical otherness, in its manner of existing, sometimes in suffering, in cognitive functioning very different from our perceptions, calls into question the posture of the researcher. Starting with descriptions of actual interview situations, the article deals with notions such as implied distance, familiarity, sensitive listening and introspection consideration of oneself. The engagement of the narrator, his or her perception of the listener and the meaning attributed to this particular communicative situation are questioned, along with configuration of an interview when there exists a hindrance to expression, reflexivity and conceptualization.