In response to the COVID-19 pandemic, states around the world closed their national borders and limited domestic travel, temporarily halting tourism. This article looks at the ongoing deconfinement of tourism and the resulting issues of hospitality in the context of Aboriginal communities’ self-confinement. Historically marginalized and further weakened by pandemics, many Aboriginal communities have chosen to protect themselves by establishing community confinement through territorial control mechanisms that prevent visitors from entering their living environment. Faced with state-imposed deconfinement, several indigenous leaders have chosen to intensify restrictions on access to their territory, forcing a reflection on territorial management in times of pandemic and for the years to come. The example of the Regulated Access Zone (ZAR) in French Guyana offers an opportunity for reflection: it allows the implementation of territorial governance tools by and for indigenous communities, for example by establishing controlled tourist bubbles in the territory and far from living environments. These reflections consequently invite further reflections on the broader issues of indigenous emancipation, self-determination, and decolonization.