In the field of health, the Internet participates in the dissemination of expert knowledge and its appropriation by users, which leads to a reconfiguration of the relations with health care professionals. Results of a pan Canadian study show the creation, by means of the Internet and its interactive tools, of an alternative collective expertise regarding trans health. This expertise allows trans people to circumvent the systemic barriers to adequate health care access, fosters their empowerment in their medical choices, and reinforces their capacity to negotiate their relation with the medical system.