Diogene’s Syndrome, a medico-psychosocial entity first defined in England 30 years ago, is a challenging issue for care-givers in the community. Management of these patients who refuse any help has led to emergency interventions, when their state of health was so damaged that two-thirds were to die during their hospitalizations. These patients in deny, isolation and filth, living as “tramps” in their own home is a real issue. What could be done to diminish this catastrophic mortality? Have these people their full capacity of judgement? Aren’t their minds sufficiently disturbed that we could justifiably intervene without their full consent? Based on a few situations, we will try to demonstrate that the mind of these people is well alive, and that it is possible to maintain them in their homes and to drastically diminish the observed mortality rates.