A musical expression activity is offered at the Centre de réadaptation Lucie-Bruneau (CRLB) for people with multiple sclerosis and their loved ones. This activity uses the creative and emotional qualities of music to facilitate contact and develop an awareness of personal potential for those involved. The activity is intended to make the family aware of the many bio-psycho-social changes that occur as a result of multiple sclerosis and improve the authentic expression of the participants’ feelings and needs. Finally, the objective of the workshop is to facilitate the emergence of action strategies for reacting to the disease. After a brief presentation of the clientele, the facility and the activity, the authors attempt to provide a summary of the major psycho-social issues of offering such a service.