In West-Africa as elsewhere, disabled women’s sex life remains highly affected by risks of sexual violence and unprotected sex. Even if authors who have studied the issue tend to assert that they are more prone to sexual related risks in comparison to able-bodied women, the explanatory reasons of this finding remain fairly explored in this context. This article aims to understand the processes that expose disabled women to sexual risks in Ouagadougou. Based on in-depth interviews conducted with 32 lower limbs disabled and blind women, the article shows through the subjective experience, how the phenomena of “defeminisation” and “hyper sexuation”, participate to enhance their sexual vulnerability . Associated to the dependency due to the absence of enabling environment, these phenomena helps to create frameworks conducive to a risky sexual life, in a context where sexual intercourse with a disabled woman assumes moreover, cultural meanings.