Growing public support towards the practice of euthanasia in situations of painful terminal illnesses provides a strong argument widely used by proponents for legalized euthanasia. This study reveals that the majority of Quebec’s population would be in favor of euthanasia for incurable and suffering patients, but showed limited support in other cases such as when the patient is not suffering, when there is hope for recovery, when the main reason is psychological suffering or when a person has simply reached an old age. Different social-demographic characteristics appear associated with changes in opinion depending on the proposed case scenarios. Other studies must be conducted to observe the evolution of public opinion toward euthanasia in Quebec in order to reach a better understanding of this complex issue.