Explain the difference between sets and lists in Python.
Certainly! In Python, both sets and lists are used to store collections of items, but they differ in several important ways.

A list is an ordered collection of items that can be indexed and modified. You can add or remove items from a list using various methods like .append(), .insert(), .remove(), and others. Lists are denoted by square brackets [].

On the other hand, a set is an unordered collection of unique items that cannot be indexed or modified. You can add or remove items from a set using methods like .add(), .discard(), and others. Sets are denoted by curly braces {}.

Here's an example to illustrate the difference:
```python
my_list = [1, 2, 3, 3, 4, 5]  # this list can contain duplicate values
my_set = {1, 2, 3, 3, 4, 5}  # this set contains only unique values

print(my_list)  # output: [1, 2, 3, 3, 4, 5]
print(my_set)   # output: {1, 2, 3, 4, 5}
```
In summary, lists are ordered and allow duplicates, while sets are unordered and contain only unique values.