Given the number of buildings present in the Kanto Pokemon map from the original Pokemon Red and Blue, what is the likely population of the entire area, and would this population be able to sustain itself?
There are no official numbers for the exact amount of buildings in Kanto. However, based on the relative size and distribution of each city, it's reasonable to estimate that there could be hundreds or even thousands of structures throughout the region.

As for the overall population, Kanto has a diverse mix of people with different cultural and religious backgrounds. It's difficult to make an accurate prediction about its potential sustainability without knowing more specifics about the local economy, natural resources, transportation systems, and other factors. However, given the historical importance of Pokémon as a popular video game franchise and the popularity of traveling and exploring new places, it seems reasonable to assume that the region may have enough support to continue hosting a vibrant and sustainable human population for many years to come.