high cholesterol
"Was on Simvastatin for approximately 8 weeks for high cholesterol.  Experienced extreme muscle weakness in arms and legs, along with severe muscle spasms at night.  Also began to have increased depression (have been on Paxil for 10 years), confusion, memory problems, and unexplainable irritability, anger, and paranoia.  After 7 days without the Simvastatin, most of these complaints have subsided, although still having muscle pain and slight spasms at night."