psoriatic arthritis
"I've had psoriasis for 35 years and  arthritis for perhaps 30.  For about 9 years I took Enbrel and methotrexate with very good results.  Despite my long-term success with this combo, about 6 months ago I decided to replace Enbrel with Otezla, primarily because I wanted to decrease my use of immunosuppressants and because of the cancer risks associated with Enbrel.   For the first 2-3 weeks I had the expected side effects, the worst being having to move my bowels 5-6 times a day.  Also some headaches.  Now, six months in, I think I am ready to go back to Enbrel.   My scalp psoriasis used to be almost non-existent but is now getting bad.  Same for my elbows/forearms.  I also have many aches and pains that I've never had before...."