plaque psoriasis
"Shots were painful, made my Psoriasis worse, developed plaque on palms of hands and bottom of feet and made other areas worse.  Since stopping it, have started Taltz which is helping but these lesions are very resistant to treatment. I went from having a mild case of Psoriasis to severe. I regret starting to take Biologics and should have stuck to topical medication. Advice do not start them if you can deal with them with topicals. You become dependent on them and then they stop working and you have to go on to a new drug with many potential side effects."