gerd
"I have been using Nexium for 10 years but not on daily basis, A 40mg would last me for 4 days before getting the symptoms again. It felt great and still feels great to get rid of that awful acidity. Causes for my GERD are eating habits, type of food (spicy, oily, sour, tea, sweets) also smoking is a major contributor. I couldn't give up on my habits and use Nexium to avoid acidity.
Recently there's been strong debates against proton pump inhibitors (PPI) which Nexium is part of. Along with all the reviews against it and how it reduces bone density. A recent study says it can result in early death as PPI alters genes behavior. 
My advice, the full extent of side effects still not fully known avoid if you can."