bipolar disorde
"This drug has been a life saver more than once. I intend to stay on it forever. I have taken it for several extended periods 6-18 months at times at doses up to 450 mg per day. I've stopped and started but eventually my depression returns. 

On 150 mg per day, I feel horrible. I have the worst agitation inside where I feel like I could crawl out of my skin. I have a tightness in my chest that will not go away. I'm unable to sit and concentrate at work.

On 300mg/day - it's like night and day from 150 mg. This is when I feel perfectly fine. The agitation disappears, and in fact, I almost feel sleepy. The chest tightness goes away and I'm able to sit and do my work for a full 8 hour day. I sleep amazing.

On 450mg/day is when I feel "normal"."