ankylosing spondylitis
"I had been suffering from Ankylosing Spondylitis for quite a number of years. I had tried NSAID's with very little improvement, therefore I had no option but to trial Anti-TNF therapy as a last resort. I had originally tried Humira without much improvement at all. I then went on to try Simponi, which improved my physical condition dramatically within the first day of the injection, however seemed to have a psychotic effect on my brain over the couple of months of been on it. I did recover once I stopped the Simponi. I then got onto Enbrel around sometime after and seemed to have improvement within a couple of days of having the injection. I did have itchiness which in hindsight was a minimal problem."