pain
"I haven't taken this Rx for long but it definitely is *not* the best option if you have no breakthrough meds. I'm on 30mg which is to last 24 hours. I'd say it does for 18. It's not horrible but I do think people will keep complaining until they are on a higher dose. The oral bioavailability of this drug is actually lower than Norco. I take Norco 10/325 tid and combined with the Hysingla it's not the worse... but I feel little relief during the day. It does however help me a bit at night. I think docs need to give higher doses than what they are of this med because it's a 24 hour med... 30mgs in 24 hours is not a lot. Well, at least I have my Norco 10/325 to help. Also, I think this med would work better if taken twice daily! But not the worst med!"