birth control
"I had two injections of depo-provera when I was 25. The first shot was fine, no abnormal physical side effects, maybe a little spotting during what should have been my menstrual cycle. Then about a month after the 2nd shot I cascaded into a deep depression that involved suicidal thoughts. My libido was also gone and it took over a year after the 2nd and final injection to feel better in terms of the depression.  My libido never recovered. I am now 45. My last sexual encounter was when I was 32. I firmly believe that depo-provera is responsible.  But hey, bright side, right? I didn't get pregnant :/"