dysautonomia
"After trying a few other drugs in combination, adding midodrine was what enabled me to get out of bed and sit up without fainting, dizziness and drastic hypotension.  I can now stand and walk, and participate in life when before, I was bed-bound.  Yes, I now have very itchy, sensitive skin and scalp; but I will gladly suffer that slight annoyance to be able to function. I am glad its a shorter acting drug, even though I have to dose in the middle of the day, because it gets out of my system before I go to bed and don't change from hypotension to hypertension."