depression
"When I started Zoloft I had tremors.  My initial dose was 100mg, but after a few months I still had issues with anger and sadness.  My dose was increased to 150 mg and I seemed to be doing better.  My sad thoughts went away.  I had no desire for sex at all.  I still felt like I could sleep all day and all night every day.  I just recently switched to Wellbutrin XL.  It was hard on me coming down from the Zoloft.  I became more sad, depressed, angry, hostile.  A couple of times I had suicidal thoughts (didn't have before or while taking Zoloft).  Pros no weight gain with Zoloft.  Cons had to cut back on my caffeine, no sex drive at all, and just didn't quite work good enough for me."