depression
"I have major depression several years, it is worse lately with suicidal thoughts. I started out on 25 mg for four weeks saw little difference other than typical side effects. The fatigue was overwhelming for 10 days but got better after two weeks. Upped dose to 50mg bad anxiety and trembling inside for about six weeks but now am happy to say I'm much better no trembling, sometimes anxious but the sertraline has definitely been worth it. I'm still not sleeping as well as I would like, waking up three times a night and getting up at four a.m. wide awake. To all of you who are just starting on it hang in there, it will get better."