high blood pressure
"Took for 2 weeks OK, then suddenly hit me like a ton of bricks.  Tingling sensation all over body, night leg cramps.  I was on the generic, then had the pharmacy switch to the name brand ($274).  The name brand seems stronger, as when I take it, 3 hours later, I get a tingling all over my body.  I will stop taking this until the effects go away and try again."