seizures
"Topamax is an uncertainty at this time.  I took it decades ago and because no med or mixture of meds controls seizures sufficiently for me I'm circling back.  I've noticed major neurological feelings (e.g., tingling) transmitting down my legs to the point that it keeps me awake for many hours, which results in sleep deprivation and then seizure activity.  It's not good at night.  One reason I stopped the med years ago is because it can cause kidney stones.  Not anything I want on top of seizures plus the tingling, foginess, and fatigue caused by Topamax."