bipolar disorde
"Buproprion XL was helpful for a season when depression was hitting very hard with Bipolar.  When I initially started taking it, I saw effects right away.  I didn't notice any false happiness like many associate with "anti-depressants" but it lightened my mood which had been pretty depressed for some time.  Over time I did notice the effect of the drug lessened and I did quit taking it, but it was helpful during the time I needed it.  I had previously tried Zoloft and I found Buproprion superior to Zoloft in my personal experience."