restless legs syndrome
"Clonidine is a fantastic little medicine and is helpful for many things. I recently discovered that clonidine is 100% effective for akathisia: an extreme motor restlessness that prevents one from relaxing or sleeping.

But for me I have to use a higher dose of clonidine. Doctors routinely prescribe 0.1 mg. but I didn't find that helpful for stopping the restlessness. About 0.2 mg. though and it does the trick. Akathisia gone; I can relax and sleep again. The only side effect is a really dry mouth."