acne
"I take 50 mg of Spironolactone twice daily for acne. My experience is very positive.

Initially, I noticed light-headedness and pronounced diuretic effects. Lost a couple of pounds of water weight. Appetite and weight gain/loss are not affected.

My skin cleared within two to three weeks. I occasionally have a small pimple or blackhead that goes away in a day or two.

My periods are very irregular. I think since I started taking this drug I've had one "real" period requiring the use of tampons. I do randomly spot/bleed from time to time. 

No mental health effects so far. If anything, I feel more stable due to the lack of periods and PMS."