renal cell carcinoma
"Unfortunately side effects for me have been horrific! I was on 800mg for 6 weeks. I wound up with nausea, extreme hoarseness,  high blood pressure,  fatigue with sleeping 18 to 22 hours a day. Took a turn for the worse and liver enzymes were high. Could not eat or drink water for 5 days and lost 30 pounds. I was off the Votrient for a month and just started back on half the dose; 400mg. So far so good one evening of slight nausea. Other than a little more tired it appears to be better."