atigue
"I started on provigil for my excessive fatigue, after my GP did virtually every blood test known, looking for a cause.  It seemed to be helping me, for which I was exceedingly grateful but then got bad mouth sores so had to stop.  I was switched to adderall, 10 mg twice a day.  It's like 2 different pills.  The morning gives me energy until about 1 p.m.  The pill at lunch seems most days, to have no effect.  I sit around and read and nap most of the afternoon, and am ready to sleep by 9.  I have sleep apnea and use a CPAP machine religiously.  Does the drug need to reach a certain level in the blood to be most effective?"