pain
"I was prescribe 50mg 4x a day and then moved to 300mg extended release.  While on the 50mg 4x a day, I noticed it took about 15 minutes to feel some relief from my joint & nerve pain.  The only problem was each dose only really lasted for about 20 minutes.  The first does ever was a oh yer finally some relief, that lasted 20 minutes. That was the reason we switched to 300mg extended release.  Again, it took about 15 minutes to feel a decrease in pain.  With the extended release, it still only helped for a short period of time, maybe an hour or two.  I stuck with it for about 4-6 weeks hoping it would build up & eventually relieve pain for a good portion of my day.  Honestly, it only cut pain by about 50% & never lasted longer than 2 hours."