irritable bowel syndrome
"I tried the 145 mcg sample my Dr. gave me.  Took it two days in a row at 8 a.m. and had a bowel motion at 10 a.m. both days. I skipped a day to experiment, and no bowel motion.  Tried it again at 8 a.m. and sure enough, a 10 a.m. clean-out.  I have no side effects, no diarrhea or pain, just a normal bowel motion, which feels GREAT for a change!  Since there's a 2-hour "wait", I'll have to make adjustments if I need to leave the house.  But so far it's the most dependable product I've used."