depression
"I went on Wellbutrin some time ago so I don't remember the dose.  I had tried at least 4 SSRI's and didn't get much relief from my depression, mostly a lessening of morbid thoughts.  The problem was that all of them without exception made me very drowsy.  So my shrink suggested Wellbutrin.  I was on it for about 3 months.  At first it seemed to make me much better, certainly no drowsiness, but after awhile I got quite depressed again.  Finally I stopped and to my amazement the very next day I felt substantially better!  I knew my depression wasn't cured but I knew for sure that Wellbutrin had made me worse."