gout
"Had my first ever Gout flare in 2009.  Since then, had about 4 attacks till 2013, but uric acid was always more than 8; some times more than 10.  In 2014, I got 2 flares in a year.  That's when I started Febuxostat.  Worked like a charm!  I'm taking 40mg daily.  Uric acid is maintained at 5.5 mg/dl since then.  I was drinking water like crazy before to maintain uric acid - didn't help. Now, I'm careless about water in-take, still uric acid levels are fine.  My doctor is very data driven, so we took baseline SGPT/SGOT (liver enzymes) test before starting the medication. Measured uric acid and liver enzymes again after 1 month, and then after 3 months.  No side effects on liver enzymes but uric acid level went down drastically. So, I love it!"