acne
"I had suffered from rather bad acne case since the age of 14. For the next 22 years, I tried all kinds of topical solutions and diets but nothing really worked except that salicylic acid reduced the severity.  I picked up on my face and my acne has left lots of scars. Finally, at age 36, I tried isotretinoin, 40 mg daily for 5 months. It was almost magical! The acne cleared permanently! I still have slightly oily skin, but have 98% less acne! After one year, I used a touch-up treatment of 1 month for 40mg. Over 5 years passed and my skin is 98% clear. The only side effect was dry and possibly thinner hair, which mostly went away once I was off the medicine. I only wish I started it when I was a teen!"