depression
"My doctor started me on Zoloft for longstanding low-level depression that was increasing due to menopause, and for possible migraine prevention. It did nothing for the migraines, but it has definitely improved my mood. I started on a 50 mg dose and the doctor had me increase it to 100 mg after a few weeks. Still no migraine relief, but I the holidays didn't depress me as they always have since my father passed away. I did notice trouble sleeping, but taking it in the morning instead of at night helps with that. Also a slight weight gain. I might try going back to 50 mg if the doctor okays it. It seemed to be enough, and I don't want to over-medicate."