depression
"I had taken Effexor XR for a year or so and wanted to see if there might be something else out there that may work better.  My doctor suggested Remeron.  Unfortunately I had a severe reaction on 2 separate occasions (6 months apart) after my first dose.  I had trouble falling asleep then could not get out of bed the whole day.  I also had very severe mood swings, to the extent of screaming at my small children when they asked a question too many times.  I had  terrible rage.  "