herpes simplex
"Abreva helps with the pain and itching that cold sores can cause.  But that's it.  The herpes virus is internal.  It sheds during times of stress or sickness.  No topical medication is going to stop the herpes virus from running its course internally.  Only oral medications taken by mouth can shorten the cycle of the herpes virus when it sheds.  Personally, I take Acyclovir, prescribed by my dermatologist, upon feeling the first tingle of a herpes cold sore.  I have found that It cuts the cycle in half.  Other people prefer Valtrex.  If you want real results during a herpes outbreak, you need an oral medication.  Keep it handy in your prescription cabinet.  Not a topical cream.  Herpes is an internal virus. Talk to your doctor."