oophorectomy
"I tried the Estradiol (Climara) made by Mylan for all of 45 minutes! First of all, the darn thing is so huge, it would serve better as a coaster for my morning coffee! I'm a small woman and could find no feesible place on my body to put the patch. When I finally settled on a place and put it there, it fell off immediately!! And kept falling off! I finally taped it to me and went to bed. The next morning, it had fallen off even with the tape in place! I never experienced this with Minivelle or Vivelle-Dot! Their glue is incredible! Great! The latter 2 cost a bit more, but it's so worth it!"