irritable bowel syndrome
"At last! A drug that seems to help. I've had chronic constipation for many years. I had endometriosis 20 years ago & the scarring & adhesions from that cause a degree of stricture on parts of my bowels.
I'm in the UK so no cost to the medicine.

My gastroenterologist has tried so many medicines with me & nothing seemed to be effective- gabapentin was the most effective out of the lot but left me really foggy-brained.

So a week ago I got prescribed Linaclotide. The first day was explosive. Probably 20 times to the loo. The 2nd day, maybe 15, the 3rd around 12. I'm now (about a week later) at maybe 8 x a day & seem to have settled out at that for now. I'm much less tired & although my rectum is sore, that seems to be settling down. Massive relief!"