insomnia
"I had severe insomnia for years which caused major major depression and anxiety.  I tried a ton of medications, but Seroquel was definitely the best.  I'm still on it at 150mg (3 x 50), which gives me 7.5-9 hours sleep/night.  When I take 100mg, I get about 5.5-6.5 hrs sleep. I take it an hour or so before bed.  It sucked for about a week when I got on it, but I have been on it for 3 years now and it's a lifesaver.  I still have nights where I have bad sleep, but it's rare.  I have had 0 side effects.  Just as a reference, mirtazipine did work for me too, but I gained weight.  Ambien never worked well and benzodiazepines worked, but addiction scared me.  Insomnia is the worst and this medicine gave me my life back."