obsessive compulsive disorde
"My son, now 19, started riluzole as part of a small double-blind NIH trial 2 years ago.  He has Autism, OCD, mood disorder, tics and ADHD.  This medication is extremely helpful in easing the overwhelming obsessive thoughts and compulsions that interfere with his ability to function. No side-effects.  I fight to renew insurance coverage each year for this off-label use and twice he ran out of this medicine temporarily and we immediately noticed a change in his behavior.  He is off anti-depressants and ADHD medicines (Zoloft & Concerta) and is now on lamotrigine for tics and mood stabilization. A great combination. His functional ability assessments (IQ) went from mild retardation into a 'normal' range.  His communication skills improved dramatically."