psoriatic arthritis
"I gave it a try for 2 months, but the abdominal pain, diarrhea, and pounding headaches never went away.  I verified that you can cut the pills to try to taper up the dosage and they start you on smaller dosed pills to begin with anyway.  After 2 months I never got up to the full dose and my side effects never got better.  I did try taking the full dose and had rapid diarrhea and had a pounding headache that lasted 3 days.  It was less successful than 3 of the 4 TNF-alpha inhibitors I had tried and less effective than Xeljanz (tofacitinib) at treating my psoriatic arthritis."