irritable bowel syndrome
"Have suffered from chronic IBS with constipation for 35 years. .. nothing has ever helped.  I would go up to two weeks with no bowel movements... spending hours on the toilet for relief.  Which usually involved severe cramping that caused vomiting and passing out.  I started linzess almost a year ago.  It has changed my life.  I started with taking it every other day AS SOON AS YOU WAKE UP! Then you can function normally through the day.  If you take it any other time it can cause diarrhea. If you want a good cleansing then take it with food in the am. My body has adjusted now and I need to take it everyday day.  What I've noticed lately is that it's not as effective anymore. I'm worried after long term use it will no longer be effective"