seizures
"Depakote sprinkles is the formula my son was taking. It was an almost too good to be true solution for him for over 20 years.  For those 20 years he experienced the following manageable side effects; weight gain, periodic hand tremors, constipation. It also gave him a much deserved good 'feeling'.  After that his seizures broke through and other side effects appeared such as hair loss, skin issues and more severe constipation.  We'll miss Depakote."