multiple sclerosis
"Avonex has been a God send to me.  I was diagnosed in 95  after experiencing several bad attacks one of which required hospitalization.  Started Avonex in June 96 one month after it came to market.   Got some side effects early on (mainly fatigue) but they soon went away. I no longer have any side effects, don't even premedicate.  The injections are little more than a minor inconvenience .  More importantly I have remained stable with no attacks.
I did experience some fatigue when starting to use the the prefilled syringe.  I quickly went back to original powdered form and remain on it to this day.  I probably could have adjusted to the prefilled syringe but choose not do do so. I expect to continue with the Avonex injections unless it stops working, I develop bad side effects, or a cure is found.  All unlikely scenarios at this point.  I expect to be on it for life."