constipation, chronic
"I have chronic idiopathic constipation due to opioid pain medications and also have chronic Hep C I'm in the fibrosis late stage ...having fibrosis of the liver affects the  secretion of chloride and bicarbonate into the intestinal luman ,mainly through activation of cystic fibrosis hence I have had cramps,pain,fullness, unable to aleminate stools completely even with laxatives and miralax I still had a hard time even getting the urge...hard stools, sometimes I would cramp so hard I would scream in pain unable to move even enima didn't work than I started this medication 3 days ago ...worked the first day well I took it in morning and went next morning and eliminated completely and I feel so much better no more fever,not nauseated anymore"