constipation, chronic
"After reading all the previous reviews of Amitiza I felt compelled to add my experience. The first morning I took it with a meal and plenty of water and went to work. Mistake!  Jeff Foxworthy jokes about the side effects of certain medications, like fecal incontinence. I can assure you it's no laughing matter when it happens to you. Within 1 1/2 hrs. it began. My stomach was full of gas, and I was worried sick all day about not knowing when my issue would start. That evening I took my second dose and about three hours later had leakage on my sheets. I had just been diagnosed with hypothyroidism and was put on Synthroid. The combination of my age, Synthroid and Amititiza=fecal incontinence according to the "eHealthMe" website."