rheumatoid arthritis
"Hydrochloroquine has been a "life saver for me" for my Extreme inner thigh muscle cramps at night ! 
      Five years ago my Inner thigh cramps were so bad and lasted so long , every night, that I could not reach the phone to call 911 for help.  I literally could not move until they dissipated.  My leg muscles were very sore the next day.
     Over the counter medications and/or prescriptions did nothing to help. 
     I read an article that said quinine might help. My 94 year old grandfather said that when he was young the doctor prescribed quinine be put in coffee to help his leg cramps.
     So my doctor prescribed Hydroxycloroquine. I have a cramp now about every 4 months and it is short and manageable.  I have no side effects and my eyes are checked every six months."