hypercalcemia of malignancy
"I began a monthly regime of xgeva injections in January 2015. After the third month, I found out I needed dental work. My oral surgeon told me that the work I needed done was extremely risky while on this medicine because denosumab prevents the bone from rebuilding itself. If they had to pull my tooth there was a chance that the hole left would never heal and my doctor said that that situation would be 10 times worse than my cancer. The really shocking thing is that getting off this medicine for a month or two before a dental procedure is almost pointless because it stays in your system for up to 15 years! I don't know anyone who can go 15 years without ever needing dental work. Also, if I break a bone, it would never heal."