opiate dependence
"Former non-IV opiate user, high doses, had major issues after detox/rehab due to residual damage to receptors in the brain. Started on Suboxone, but was unfortunately sensitive to the nalaxone included to prevent abuse (for me it caused headaches, low blood pressure and nervousness which all abated after switching to Subutex [buprenorphine]). Doctor asked if I would try Subutex before resorting to a methadone clinic (for some people, especially IV users, I believe it is a great tool...but not for me). I obliged, and suddenly my dose didn't need to be as high (from the ceiling around 32mg down to 28, then 24) and negative side effects all but ceased. And all of this with no real "buzz" like I'd experienced from methadone in the past."