ibromyalgia
"I have been taking Tramadol for about 9 months.  A fortnight ago I started taking Panadol at the same time as my Tramadol after reading a study.  In my opinion it makes the Tramadol 4 times more effective.  I used to take it between 2am and 5am to help me get out of bed now I take 100mg with 1 Panadol before bed, and then again when I get up - I actually can now.  A big thanks to both the people who made it and thought of mixing it with Panadol!"