chronic pain
"I've been on 60 mg/day for the last 17 years after I developed multiple neuropathy issues in my extremities after chemotherapy treatment. I've tried EVERYTHING else on the market that I can legally try. Methadone is the ONLY thing that works and doesn't get me high as a kite or knock me out. I will warn anyone that this medication is Very dangerous as far as CNS depression goes for the first two weeks of use. I was nodding off all over the place! The great thing is that this goes away after the first few weeks. After the initial period, I have noticed very few side effects. The ones that I have are the usual constipation that all narcotics produce. This medication will lower testosterone levels after long term use. (Longer than a year.)"