depression
"I have chronic depression (dysthymia) & anxiety, & the depression worsened recently despite being on Zoloft & Wellbutrin. My psychiatrist suggested we try Rexulti & wean me off the Wellbutrin. 

I started on 1mg, & I had a slight headache for the first two days. After that, I felt like I was doing a little better and my husband commented that I was more active than usual. My dose went up to 2mg a couple days ago. Now I feel like I can really tell a difference! I haven't felt depressed, I have more focus and creativity at work, & I've actually had enough motivation to do chores at home. I'm a little restless, which I'll keep an eye on, but I haven't noticed any other side effects besides that and the temporary headache. I'm optimistic!"