polycystic ovary syndrome
"I have taken Metformin 500 mg once daily in the last 6 month. Finally I got to the Endocrinology and they put me on 2000 mg per day. 
Now I am slowly increasing the dose - I had bad diarrhoea, cramps and everything you can imagine!
Hopefully the side effects will go away - because otherwise I have no problem with it. Slow but steady weight loss, no more food cravings, and crazy frustration if I can't get my hands on carbs.  I noticed I don't really want to eat oily food,junk food....which is brilliant!"