depression
"I was on generic Bupropion for almost 2 years (Hcl XL 150 mg) and it was ok. It did help with the depression but towards the end of the day (took pill 7 am) by 5 pm I was feeling down and irritable again, I never really thought about it until everything I've read about the generics having time release issues so I know it's not just me!  I def had more energy, and was good during the day, but 5pm I shut down emotionally. I tried switching to generic Bup Hcl XL 300 mg last year but only made it 5 days in before switching back due to anxiety/no sleep side effects. I really hated that my mail order RX company would switch manufacturer of my drug-one bottle was from Global and the next Actavis. Now on brand Wellbutrin XL300mg and hoping it wrks!"