constipation, chronic
"I began taking Amitiza twice a day in 2007 and like others in this room swore by Zelnorm.  My experience has been great, although it seems I need to stop taking it for a few days every 4 to 6 months to reboot, so to speak, as it begins to diminish effectiveness.  I'm curious if the extra long colon plays into our problems?  I deal with this as well."