rheumatoid arthritis
"Within 2 weeks Xeljanz was working amazingly for my rheumatoid arthritis.  But had to stop after 8 weeks because of complete insomnia and depression/anxiety.  This drug brought on depression, insomnia, and anxiety so hard and so quickly.  I just could not continue.  This had the same effect on me as prednisone.  My system cannot tolerate that either.  Too bad because both work so well for the arthritis.  Luckily these side effects have gone away after stopping the medicine"