osteoarthritis
"After using Synvisc for years, I tried Synvisc-One this week. The process of Synvisc was somewhat painful and I walked away with minimal pain. Synvisc-One was excruciating. For the first time, the injections (one in each knee) were incredibly painful. I sat for 20 minutes in the exam room working up the nerve to walk to the waiting room. Then I took 30 minutes to work up the nerve to walk the 35 yards to the car. After 3 days, I am starting to walk again without severe pain. This was the first time I had it, and in 6 or 8 months I'll do it again. Just know it is a bigger syringe, a bigger dose, and a much bigger needle. In the end, I believe it to be a good cushion for my knees, and will be longer lasting."