constipation, drug induced
"I've been going on and off opiates for around 8 years since my chronic pain began.  I would go off the medicines to get relief from the horrible constipation they caused.  A few years ago I discovered that I was constipated even when I would go off the medicines, so I must have messed something up by using laxatives for so long.  I tried the subcutaneous Relistor that I had been desperately waiting for for years, and unfortunately it didn't help."