narcolepsy
"My experience with Xyrem started about 12 years ago.  The first few months where very hard.  If I moved after taking it, I would vomit.  The headaches were almost unbearable and I lost weight, but after the first few months and 12 years later, the only side effects I have now are night sweats and I can keep that in control if I drink enough water throughout the day.  I can't even remember my life before Xyrem but I know that it gave me my life back."