bipolar disorde
"Bipolar 2.  Seroquel XL 400mg at night for last 5 years. Quetiapine has been great for me. I no longer get any more than slightly hypomanic and don't get depressed at all.  My anxiety and paranoia have disappeared altogether.  I take it with 75mg venlafaxine 2 hours before bed time and sleep like a log with very little hangover the next day.  Side effects - after 2 hours of taking very dry mouth and unsteady on feet, weight gain - put on a stone all round my middle.  It is the only medication that has worked for me.  The disadvantage is if you need to get up in the night, your tongue sticks to the side of your mouth which makes you slur and you can't think straight."