migraine
"I have been suffering from migraines for over 20 years. My migraines are hormonal but also stress related. First time I took sumatriptan I couldn't believe how effective it was. My migraine disappeared in only 15 minutes and I was able to live my life as a "normal" person instead of lying on bed all day. Unfortunately the magic only lasted a few times. I realised every time I had a migraine it took longer and longer for the drug to act. And also my migraines were more frequent since I began using sumatriptan. 
I stopped taking this triptan and my doctor suggested another one (zolmitriptan) which is working really well for me and I only have 1 migraine per month now."