high blood pressure
"I started taking this medicine in 2006. It works to take the pressure off my heart but it has caused me arthritis in my knees, hands and feet.  Now I am in pain most of the time.  My hands have developed arthritis in both thumbs, my feet have it in my toes.  I tried another Astra Zeneca product called Atacand and it works better but is so expensive I can't afford to buy it."