constipation, chronic
"I was nervouse taking this at first, always have been afraid to take laxatives. After about 2-3 weeks now I've noticed that for the first 12 hours or so after taking Linzess, I have no appetite and very loose BM almost to the point of diarrhea. After that 12 hour window, I'm right back to constipated and in pain from the stomach/intestine cramps. Need to contact the Dr to see what to do now."