acne
"I was terrified to use epiduo after reading the reviews but once I realized I had to buffer it, it seemed much more approachable. If you're not used to using retinoids, don't put this directly on your face and don't use it every night. I took a pretty conservative approach and mostly been able to minimize pain/flaking. 

Here's what I do:
-Wash my face with a gentle cleanser (I use Aveeno Positively Radiant)
-Put on some cerave moisturizer
-Wait 20 minutes
-Put on the epiduo forte

I only do this at night, once every 2-3 days. If I feel my skin getting irritated, I'll stop using the epiduo till it gets back to normal. Don't muck around with your skin! If it's irritated and awful, no reason to torture yourself and use the epiduo every night just use it every couple of nights"