opiate dependence
"It is difficult when a relapse occurs, a patient needs to wait about 24 hours from their last opiate use before they can begin the suboxone again. Many opiate addicts become "sick", and are too tempted to take the suboxone too soon. Then because they take the Suboxone too soon, they become even MORE sick, because the Naloxone antagonizes the opiates still in the body. I've experienced this myself because I tried so hard to wait out the time and couldn't bear it. So I took the Suboxone early and felt like I've never felt before. I had the feeling of jolts in my legs. My skin felt like there were bugs crawling on me, I felt so internally cold, as if I were in a refrigerator, etc. But waiting 24 hours is too long."