pain
"I have severe, constant pain following 4 serious car accidents (none my fault) over 14 years. I was taking Oxycontin 10 mg x5 per day and my Dr. recommend I try Nucynta. I don't know why. It was more expensive and not available in a generic form.

After three days I felt it was less effective in controlling my pain.  On the fourth day I woke up and felt I had nothing to live for and my life had no meaning. I have depression and PTSD caused by the accidents but these conditions  are well controlled by other medications. I normally don't have these thoughts.  I beleived this was a side effect of the Nucynta so I immediately stopped taking it and those thoughts went away right after."