constipation, chronic
"It worked very well and quickly from the first dose, but has a side effect that is not listed.  I have type II diabetes and after taking the pill, my blood sugar drops sharply.  I take the medicine, then eat a big breakfast to counteract this.  Also, if you go to drugs.com, you will see a list of drug interactions and none is listed at the pharmacy or on the Linzess wedsite.  If you take an antacid, the Linzess doesn't work.  There are quite a few drug interactions if you care to check it out."