constipation, chronic
"I have experienced chronic constipation since I was diagnosed with systemic lupus 15 years ago.  I have tried nearly every over the counter remedy with only short-term relief.  I have been on 185 mg Linzess for a month and am happy when it actually works.  Maybe it is too soon to decide if it is a great drug to relieve my constipation, but so far, it only stimulates a bowel movement 2-3 days/week; most often within 2 hours of taking the drug on an empty stomach.  The other days, I am bloated, constipated and full of gas."