depression
"I started on 10mg of Trintellix after a short stint of being drug free.  Previously on 10mg of Cipralex.   10mg of Trintellix didn't give any relief from anxiety and very little if any help for depression.  I moved up to 20mg and nothing.  On to 30mg now for about 5 days.  I will give it a another couple of days and then back to Cipralex if it fails.   Apparently Trintellix has been under dosed by many GP's.   New drug, what can you do?"