acne
"Although there are many side effects which it can cause, even if one or two of the serious ones come, it could be worth it in the end.  I know the depression and isolation from very severe acne, never wanting to go outside because of how horrible my skin always was.  The only medication that actually worked for me was Accutane.  I realize that it gave me slightly blurred vision, but the result from using it was fantastic.  For anyone without severe acne who doesn't know how horrible it really is, they can't understand it, but when the only thing you want is to have clear skin, the risks are simply worth it."