plaque psoriasis
"Taltz caused severe swelling the size of hockey pucks that lasted an entire week at injection sites for the initial two injections (mid thigh). Thought is was just my body adjusting to the new medication but upon week #2 injection, an even worse reaction! Same "hockey puck" under my skin  as week #1 & spread to 8" hardened "pancake" under the skin with redness, severe swelling, itching (for a week and counting).  It is painful and radiating heat, an under the skin "hive". My doctor believes I may be reacting to a certain protein often used in injections. I was on Stelara=no improvement, tried Humira and had some improvement but problems getting product shipped at proper refrigerated temps and flimsy injections needing to be replaced."