motion sickness
"I have been taking dramamine for years (since I was a child) to prevent my terrible motion sickness. It works incredibly well at keeping me from getting nauseated. My only problem with it is that it makes me so drowsy! If it is a shortish flight or bus ride, I still get nauseous but don't always want to take a dramamine because I'll be so drowsy once arriving at my destination. A 4+ hour flight/bus/boat though, and dramamine is for sure the way to go, particularly if it is overnight travel and you will be wanting to sleep anyway."