alcohol dependence
"For 8 years I have consumed on average 90-120 drinks per week (i.e. a drink bring a beer or glass of wine or 1.5 ounces hard liquor).  Within 6 weeks on Naltrexone, the number dropped to 60.  After 3 months, it is at 30 drinks per week.  Next target is 15 drinks, the "safe" normal limit.  Then onto nothing.  It works.  Don't cheat...take it 1 hour before drinking and see a psychologist specialized in addiction too.  Naltrexone is not a silver bullet, but is part of the arsenal to combat alcohol dependency."