inflammatory conditions
"I was put on prednisone for the first time for a rare form of colitis. I was in terrible pain and had to use the bathroom about 20 times a day. I was hospitalized with dehydration and vomiting and the extreme diarrhea. After six days on a high dosage I was much better and sent home on a maintenance regimen of 10 mg. per day. 

This therapy did not cure my condition but cut down on my frequent hospitalizations. So, to make a long story shorter I was prescribed prednisone in differing strengths for twenty years. At that point prednisone had done so much harm to my body that I insisted on stopping it. I have developed severe osteoporosis and my back is starting to get a "hump". My skin is so thin that it is like tissue paper and I get bruises all over me."