depression
"This caused night terrors (the weirdest dreams of my life), absolutely horrific panic upon waking up, constipation worse than an opiate, aggressiveness and anger, uncontrollable shaking, restless leg syndrome, headaches, nausea, terrible gas and bloating. 
It's basically a research chemical approved by the FDA. It was only 'discovered' in 2011. Yes, the first day I was on it I had a sudden uplift in mood, but other than that ..... this stuff is poison, I'm convinced of that. I've been on many different antidepressants in my life. 
I did not combine brintillex/trintillex with anything. I had not been on an antidepressant for months before starting it. 
Do not take vortioxetine. It is not safe."