osteoarthritis
"I took this more pain in my shoulder - I had a shoulder replacement years ago.  I have had trouble with my bowels for years, colitis, diarrhea, etc. I usually take 2 loperamide to keep it somewhat under control. The very next day after taking prednisone, my bowels suddenly calmed down. I feel like a changed person. I have been experiencing normal bowels now for 4 days so far, no explosions, sudden urges to evacuate. Next time I talk with my primary physician, I will tell her about this."