depression
"I have a history of major depression and have been taking a daily dose of 300mg of bupropion XL for the last 4 years. It's important to note that everyone responds uniquely to medication, but for me, bupropion has been wonderful. Unlike the SSRIs and SNRIs that were prescribed to me early in my treatment, bupropion does not make me sleepy or negatively impact my libido/ability to orgasm. I did experience some nausea when I first began taking it, but this passed quickly. It took about 8 weeks to kick in completely for me, and I haven't had a depressive episode since I've been on it. My weight has remained stable. "