constipation, chronic
"I'm a 25 year old female who has had BMs every 7-9 days since I was 10 with no real answers.  I had tried everything, nothing worked.  I did not feel the sensation of "needing to go" despite the pain and discomfort in my abdomen and could only have a BM if I removed it myself with manual disimpaction.  This was, of course, disgusting and very inconvenient.  It eventually became normal for me and I had almost given up at ever finding treatment.

I started taking Linzess 290 mcg nearly two weeks ago.  Nothing happened for six days, and then I had a small, well-formed BM.  I never had any explosive diarrhea that many others experience with this medication.  My BMs are now every 1-2 days, small, and still sometimes have to be removed manually."