major depressive disorde
"As a "thick file" patient, after nearly thirty years of suffering through dozens of combinations of drugs for TRMDD, and this little gem has had an impact far exceeding any other treatment.  One milligram Rexulti as an adjunct to 60 mg mirtazapine/200 mg bupropion has given me a chance to move forward.  Reduced dependency on alprazolam, nicotine, ethanol in the first thirty days.  Am hoping fervently that there's not a "poop-out" potential with Rexulti, and am making hay while the sun shines.  My psychiatrist is shaking is head, having seen likewise highly significant movement in a good number of long-time treatment resistant patients, because "on paper, it looks just like Abilify".  Not placebo effect in my case."