ibromyalgia
"I prescribe Tramadol for patients, for some it does not work because you must have the enzyme to convert it.  For the people who have the converting protein it is a wonder medicine. For many with fibromyalgia & chronic pain it works well and allows them to continue working & activities.  For all medications there are reasonable limits to the amount used, and precautions for some when tapering and discontinuing.  With Tramadol slowly taper and discontinue, do not stop cold turkey.  I found Tramadol to be effective with 1 or 2 tablets (50 mg) a day, occasionally on a severe pain day I must take up to 200 mg in 24 hrs.  4 days a wk I only take 1 tab!"