psoriatic arthritis
"I had an awful time with Methotrexate side-effects but the disease went into remission and I stopped.  Two years later it was back and this time we tried Humira.  The psoriasis cleared up after about 8 weeks and the arthritis inflammation disappeared.  It's been about a year today with no side effects other than fatigue at the end of the work day.  I'm 61 and feel I can work another 5 years.  Without Humira I don't think I could.  Great drug, but too damned expensive.  Bring on the generics."