constipation, chronic
"Interesting reading all these negative posts.  I have been hospitalized three times for blocked bowels, and the treatment is nether cheap or pleasant.  After keeping a diary for my GI where I had pain almost every day for six months he prescribed Linzess.  First couple of days had no results, then it started working.  Very predictable and yes I do need to be near a bathroom for an hour or two after I take it.  After that everything is under control.  I feel wonderfully better and have much more energy.  I do believe you should take it on an empty stomach, then eat something about thirty minutes later.  On a few occasions I have taken a second dose in the evening if I felt uncomfortable or needed to skip the morning due to appointments."