bacterial skin infection
"Bactrim ds cleared up my infected finger, just like most antibiotics do. The difference is in the side effects. The nausea and diarrhea are worse on this one. But the biggest problem was that my depression which I had under control with medication became worse than ever overnight. I don't know whether it interfered with my antidepressant  (bupropion xl) or just aggravated the symptoms so much that it was uncontrollable. Either way, I spent a week alternating between despair and rage on a hair trigger. I would not try this again."