opiate dependence
"My biggest problem was ease of use.  The patch did not stick well to my cheek. It would often almost immediately start to roll in on the edges, sometimes ending up as a small cylinder and other times ending up completely stuck to my teeth. The rate of absorption was thus very different from dose to dose. I wasted quite a few Patches because I would often have to re apply. For me, this dosage form was not easy to use and not consistent.."