bipolar disorde
"I was prescribed with sertraline a few years ago for MDD and bipolar disorder.

Even tough it took some time to produce positive effects, sertraline was, indeed effective (especially when combined with bupropion and escitalopram). The mood variations disappeared, depression decreased.

From the negative side, it produced a decrease in libido, and an extreme decrease in creativity. If you are a composer, a painter, a writer, etc, you should, in my opinion, expect a possible and very pronounced decrease in creativity during the its use. The temptation to interrupt the treatment for the benefit of recovering the creativity should be strongly resisted."