diarrhea
"I am taking Lomotil because I had surgery. Then bone infection set in and I had to take IV antibiotics which caused extensive diarrhea.  The first day I took Lomotil, it worked great for about 10 hours, but the following days, decreased in its effectiveness. By the third day, it was no longer working for me, but I attribute this to the antibiotics.  I will have to let my doctor know so that he can possibly prescribe another anti-diarrhea medicine or change my antibiotic."