major depressive disorde
"I have been on Vortioxetine for three months and it has been the only antidepressant that has ever worked for me. I have tried most of the alternatives meds and have years of taking therapy none of which worked. Although there are some initial side effects, mainly nausea and constipation for me, is worth persevering, as these wear off. 

Although, I do feel slightly 'dumbed down' I don't see this as a particularly bad thing as I often used to over think everything and I now feel content for the first time in my life. I know 'one shoe doesn't fit all' but for my particular 'chemical imbalance' this drug has been life saving."