pain
"After spending years on very high doses of tramadol, Nucynta has worked better than any amount of tramadol or any of the other narcotic pain killers I have used. This medicine is closely related to tramadol (depending on who you ask but most say yes it is). They tweeked tramadols formula to make it much stronger so its just a narcotic. I am able to take Nucynta for breakthrough pain once or twice a day. My baseline pain reliever is Ultram ER 300mg. I take Cymbalta as well as the other two, so the doctor and pharmacy dude like to whine about serotonin syndrome. Nucynta is like tramadol in its anti-depressant makeup. I have no side effects probably because I'm used to tramadol. "