rheumatoid arthritis
"Severe rheumatoid arthritis (RA) flare presented in 2006 after a traumatic wrist injury/surgery. Enbrel did not work for 6 months and then mostly worked. Until the end of 3 yrs. Developed Polymyositis in addition to RA. Creates total weakness in the large muscle groups, balance problems, and of course depression. Taking about 20 different medicines, including steroids afterwards. No significant relief except when on steroids greater than 20mg per day. High dose of steroids for past 2 years. Just tried Rituxin infusion therapy. First drip went fine. 2nd infusion caused an allergic reaction. Back to square 1."