acne
"I have been on spiro at 100mg for about seven months. First, the plus side is that I have had almost no side effects. I only experienced side effects when I temporarily increased my dosage to 150mg to control a bad outbreak. Even then, the side effects were just headaches and having to pee a lot. 

The down side is that it never fully cleared my acne. Where I started spiro, I would say I had moderate acne, which I've had since middle school (I'm 18 now). I now have mild-moderate acne, depending on the day. The last few months I haven't had a single completely clear day. Overall, I'm disappointed. This was supposed to be the thing that finally worked."