rheumatoid arthritis
"Diagnosed with sero negative rheumatoid arthritis about five years ago.  It came on very quickly and pain was awful. Took methotrexate, but was quite ill from side effects.  Thought I Achieved remission and stopped methotrexate. Unfortunately, the disease was active and recently had a flare that has lasted for months. Blood work all negative. Rheumatologist ordered an MRI and found bone erosion in the wrists.  Started Humira and had relief of symptoms shortly after.  Just took second injection.  The nurse who instructed me on the shots said to leave it out of refrigerator for 30 minutes, ice the site and inject.  I have done both injections in my stomach with no pain.  Using the Humira pen.  Also iced spot for 5 minutes afterwards"