depression
"It's an okay medicine for depression, but I've had times where I'd miss one day of Cymbalta and immediately feel withdrawal symptoms (brain zaps, nausea, headache, etc...) The only other medicine I've ever had this happen with is Effexor. I hate that I have to make sure that I have to take this at the right time of day, because even being late by like 6 hours, I feel the withdrawal symptoms kicking in."