depression
"Have dealt with GAD anxiety most my life. Started taking Effexor for a Major Depression episode.  Doctor stared me slow.  33 mg for 4 weeks, then 75 mg for 3 weeks, then 108 mg for 2 weeks and finally 150 mg.  Been on 150 mg about 6 months, some side effects along the way.  Just basically feeling "weird" was the worst side effect.  Wanted to quit many times along the way, but stuck with it.  It doesn't work overnight. 
Sexual side effect is hard to have a orgasm, but I can deal that if I feel better.  Depression
is NO fun.  Good Luck All.  Tomorrow's always can be a better day.  GOD Bless."