benign prostatic hyperplasia
"Uroxatral saved my bacon for years.  Then generic came out and twice I tried to switch.  All I got was same side effects, but no positive outcome.  So switched back to brand name... but that has increased 300% in price since the generic came out.  It's as if they know the generic is not as good and that they are the only game in town so they're up to $20/pill and no insurance will cover it even though generic simply doesn't work and the other two drugs have more serious side effects."