sinusitis
"Started meds on Monday.  My arms and legs hurt terribly Tuesday and Wednesday.  The headache has been the worst I have ever had.  Chills, sweating, nausea, impaired vision, insomnia.  I called the Dr's office Wednesday afternoon and the nurse told me to give it a few more days. Went to different Dr on Saturday and he said bactrim is notorious for headaches and other adverse effects. Off of it now and have to wait 24 hours before I can start a new antibiotic.  I'm praying this headache ends soon"