depression
"I was on Wellbutrin years ago, and it helped.  In the last couple weeks, I have been suicidal and VERY depressed.  My doctor put me back on the Wellbutrin, and 2 days later I'm ridiculously happy!  I think it's worth the side effects, but some may not.  I've experienced: Insomnia, lack of appetite, horrible nausea, and incessant twitching (every 8 seconds or so).  The insomnia is horrible.  I've gotten about 2 hours of sleep in the last 3 days.  Lack of appetite is okay with me, I needed to lose weight anyways!  Ringing in the ears is something I'll deal with, but the nausea and twitching are the WORST by far.  I look like I'm having a small seizure sometimes, and the nausea is just...ugh..."