constipation, chronic
"I have has chronic IBS with constipation forever. At one point, I thought I had an obstruction, but didn't.  I went to a gastroenterologist and she prescribed 8mcg of Amitiza twice per day. It worked pretty quickly, but then didn't seem to anymore. I had a lot of the side effects that other people mentioned including gas, bloating, and bad stomach pains. I now take two 24 mcgs per day and figured out that if I take one before bed and one an hour before I get up, I don't have major issues. I go every morning completely and feel great for the rest of the day. I hope this helps other people trying this medication."