osteoarthritis
"One day after the first injection I could tell a difference - no start up pain.  The injections were painless.   The doc put a cold numbing substance on the skin and when he injected it I couldn't even feel it.  I had my last injection this morning, equally painless (the PA did it this time).  I still have a lot of stiffness and am hoping now that I have all 3 to see some relief in the next few weeks."