depression
"I have it all...anxiety, depression and insomnia.  Sometimes I can be anxious in the morning, depressed in the afternoon. Have tried Wellbutrin/Cymbalta combination, Pristiq, Viibryd, Effexor, and every SSRI.  I definitely felt an improvement with Cymbalta/Wellbutin and Pristiq, but not 100% myself.  Remeron has been a God send to me.  It works fast; dare I say I am in a good mood again after only three days. I was a bit tired in the morning, but I will gladly take some fatigue to rid of the anxiety and depression, and I hear this goes away in time.  As far as the weight gain, I have always been a good eater and go to the gym, so if my appetite increases (it hasn't as of yet) I will just have to monitor it. So far, it's been great."