depression
"This medicine saved my life. I have now been on it for 12 years for anxiety and depression. I tried a whole slew of SSRI's over a three year period with minimal success prior to clomipramine. A week after starting clomipramine I started to feel better but had some major side effects (dry mouth, constipation and later weight gain). With the SSRI's I had no or minimal side effects. I thought maybe these side effects mean the medicine is working. The side effects continued for about 5-6 weeks but damn I started to feel like my old self. I gained about 15 pounds in the first 8 months but I didn't really care because I could live again and enjoy my family and friends. The weight all came off after about a year with exercise and eating right. Awesome!"