angina
"Before Ranexa I could not go a day without needing a nitro for the chest pain. Now if I need 1 nitro a month that is a lot.  BUT the side effects are terrible. The bloated feeling and stomach aches are terrible and the constipation has been so bad I need to use MiraLax daily along with a stool softener in the morning and evening. Do not know if I can tolerate the GI problems much longer."