osteoarthritis
"I received my 1st Euflexxa injection today in my right knee. I'm only 30 but have had knee problems since I was 9. I'm now bone on bone in that knee, and my left isn't far behind. I can't have my Fulkerson until the last shot  6 weeks, so it's either do the shots or live with my pain. I must say, this 1st shot has left me in a world of hurt. The shot itself was pain-free (having used ethyl chloride numbing spray) and I walked out perfectly fine. Here it is, 8 hours later and my knee hurts worse than it has in a while. I hope after I hit that 2 day mark it will get better. Only time will tell though. I just wish they'd tell you the '48 hour pain' could be this severe."