depression
"I have dealt with moderate to severe depression on/off since my early 20s (I'm now almost 40). I have several antidepressants and found Zoloft was the only med that worked, so I remained on a dose of 100 mg for almost 10 years. I did try to wean myself off on 3 separate occasions, as I no longer wanted to be on pharma drugs, but every time I had terrible withdrawal symptoms. I finely decided to try St. John's Wort instead. I have been on 900mg daily for close to 1 year. St. John's Wort was helpful in combating the withdrawal symptoms I continued to have even weeks after discontinuing the Zoloft, but I continue to have mild depressed mood with irritability. I am going to stop St. John's Wort and try 5-HTP."