constipation, chronic
"Today, I used the 145mg dose of Linzess for the first time.  I suffer with constipation due to the daily use of Methadone to control Restless Leg Syndrome.  I'm glad I took this first dose on a day when I could stay home.  Within 2 hours, I needed to make an urgent trip to the bathroom.  It was a quick trip.  I thought I might have to go quickly again, but I did not.  However, I did feel a little shaky for a while after that.  I rested, and then I felt OK.  No more urgencies to, uh, take care of.  And I feel OK, pretty normal.  So, I don't think I'll take this before work tomorrow, and I'll have to figure out how to fit it into my schedule, but it sure worked quickly and completely."