bipolar disorde
"Lamictal has been a lifesaving mood stabilizer for me. The only serious downside is that it causes what I call 'old lady skin'- thin, fragile, and poor healing, as well as mucous membrane fragility. 

I initially did very well on 200 mg and suddenly developed severe rash eight months in (rare for it to take that long). I successfully (and slowly) rechallenged, and 200mg is where the skin issues kick in. I'm back down to 150mg and my slow-healing bug bites from the summer are finally fading away!

HOWEVER, even if I had skin like the Crypt Keeper for the rest of my days, I can't praise Lamictal enough. It gave me my life back. What's a little skin in exchange?"