osteoarthritis
"I am 73 and just found out  I have torn ligaments, tendonitis and arthritis in both wrists. For about a year now I have had stabbing pains in my wrists and hands. After taking three Arthrotec 50 my pain is gone. But, I also have a gastric problem with reflux and for the last two nights have had extreme bloating and reflux. I took the fifth tablet this evening. It is so bad tonight that I have to stay awake. I can not go to sleep, even while sitting up in a chair for fear of having the reflux again. I have had the reflux two times already tonight when I dosed off. So I am here now  typing this at 4:30 AM so I do not fall asleep again. The Arthrotec works, but I can not take any more of them."