major depressive disorde
"It was very difficult titrating up to 20 mg of Trintellix. I started at 5 mg one week; 10 mg the next week, 15 mg the following week until I reached 20 mg. The nausea, vomiting, and dizziness were almost unbearable; I missed 2 days each week for a month while starting it. Thankfully I was on FMLA and was able to muscle through it. I have been through almost every SSRI, SNRI, etc and nothing but electroconvulsive therapy worked for me. After the first week on Trintellix I felt happy for the first time, actually happy, which is why I muscled through the side effects. I have been on it for a year now and it is a miracle pill. Make it through the first month and all side effects go away."