chronic pain
"I have been taking Ultram/tramadol for fifteen years four/day.  It is usually but not always effective.  I often have to add the NSAID Naprosyn.  I have neuropathy and other side effects from chemo and osteoarthritis also from chemo.  Many joints have no cartilage.  I am concerned about chemical dependency and consciously avoided codeine or morphine.  The Tramadol gets me through the average pain but not the severe pain.  I really wish someone would come up with an analgesic that was both effective and nonaddictive and did not diminish alertness and effectiveness."