ibromyalgia
"I was diagnosed with Fibromyalgia about 10 years ago and have been on many different Rx regimes including Tylenol 3 and 4, Cymbalta, Lyrica and
Tramadol with Tramadol being the most effective. At my highest point I was up to 400 mg per day and that just made my entire personality change for the worse so I backed off to 50 mg 
4 times a day. Recently I have experienced severe gastrointestinal issues all pointing towards the Tramadol usage so I decided to wean myself off it. After 2 days at 100 mg a day big trouble, now have insomnia,  anxiety, foot cramps, sweats, agitation and overall pain."