constipation, chronic
"Linzess is a savior for me.  I took it for a year(low dose) every 4- 5 days.   I then began taking it every day.  It stopped working for a month.    I took some laxatives and then I re started Linzess  and only took it ,once again, for every 4 or 5 days. Once a day wasn't natural for me because I  had chronic constipation since I was a child.  .  When I started taking it every 4th or 5th day it started working again..

The only problem with this drug is that  it isn't consistent in it's effects so, to be safe,  I stay around a bathroom all day and wear an adult diaper if I plan to be out for a few hours."