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"I received a sample of Synjardy and have only been taking it for 4 days.  I started off taking 850mg of Metformin twice a day and 5mg of Glipizide twice a day.  I had good numbers on this, but the Glipizide was causing too many hypo episodes, so my Dr gave me a sample of Synjardy.  The Synjardy has made my numbers more consistently 80-105 and I no longer have any hypo events.  I have also lost 4 pounds in 4 days.  The only negative I have noticed is having to drink and pee more.  It has made me more prone to waking up a little earlier to hit the bathroom, but it hasn't been that bad.  They have a savings card, but my insurance will not cover it at all, so I can't use the card and without that it is $431 a month, which I can not afford."