high blood pressure
"prescribed to wife - a kidney dialysis patient in her 14th year of treatment --(haemodialysis) to control bp - died within 2 months of being prescribed.  BP escalated to an alarming rate - seven hour nosebleed - if this is not an isolated instance of such a severe reaction - strongly suggest it NEVER be prescribed to patients known to have severe kidney impairment. Would be interesting to know if any mortality studies have been done regarding the use of this drug on kidney dialysis patients. Noted that it raises the level of potassium in the blood which I suggest of itself is an indication that its use in such patients is perhaps contraindicated."