urticaria
"I was a very healthy 52 year old female until my first Urticaria attack in June of 2013.  I was taken to the emergency room and treated with IV Benadryl.   I was back in ER with the same symptoms 24 hours later.  Like many of the posts I read here I went through prednisone, cyclosporine, lotions, potions, etc and about 5 prescription anti-histamines a day from June of 2013 to October 2013 trying to get relief.  Nothing worked and I was miserable - not to mention drugged .  I found a very good doctor who introduced Xolaire to me.  I received my first Xolaire injection in October 2013 (prior to FDA approval for CIU) and am still on it Feb 2017.  It's a miracle drug."