immunosuppression
"Currently taking 16mg of Medrol once a day as part of undergoing IVF, although I've taken it in the past at smaller doses to help with my chronic, moderately-severe asthma, which worsens in winter.  While I love prednisone for what it does in helping me breathe (and hopefully in successfully helping me achieve motherhood), I hate its side effects.  For me, the biggest problem is the anxiety (though weight gain isn't fun).  I already have an underlying anxiety disorder, but taking this, especially in higher doses makes me feel truly "crazy."  Panic at unbearable levels, insomnia, sweaty, clammy hands and feet, racing heart, irrational/inconsolable....the whole nine yards.  I use it strictly as a last (or only) resort and not without caution."