bipolar disorde
"I take anywhere between 112.5 and 187.5 mg of Effexor XR. It is the only thing that has worked on my bipolar depression. It has been a miracle medicine for me. 

Nonetheless, one has to be careful. I was manic on it at 150 mg without a mood stabilizer. Now I take 20 mg Abilify with it, and it is working great."