underactive thyroid
"I read that the proper time to take it is early in the morning before food.  When I tried it this way I had the most horrible side effects of my life.  The inside of my mouth, gums, tongue were burning up so I couldn't brush my teeth and my lips swelled up to twice the size.  I had taken it before at night without this problem.  So now I take it in the middle of the day after food and it is okay."