pain
"This is an anti inflammatory.  If you have a serious inflammatory response in your system, this will take time to reduce your pain. It is not like oral pain relievers with near immediate results. Patience is needed. If you're having trouble with it adhering to the skin, make sure the area is free from oils, either naturally or lotions or soap residue. I have no problems at all with them. My RA flared up in addition to my cocyx broken off, literally.  The pain  was so severe that oral meds weren't effective. It took several days to feel the beginning of relief, and I've improved steadily. If you've used these short term and are the impatient type, chill out and give them a chance. They do work."