pain
"Switched from Butrans 20mcg to Nucynta ER 100, but wasn't enough for mid to end of work day, so PM switched me to 200mg x 2 daily. So far so good, no side effects and much better control of the pain along with being in a better mood overall. Degenerative Disc Disease and muscle spasms are my main culprits over past 8 years, 33 now. I've gotten to the point where epidurals seem to be the only thing that will allow me to live a close to normal life. 

Nucynta has really kept things at a manageable uncomfortable level compared to before. I hated the roller coaster of non ER (extended release) meds and highly recommend making the switch if permitted."