keratosis
"Four years ago, I used Zyclara for two weeks, took a two week break, and continued the second cycle for one week.  During the first cycle, I experienced flu like symptoms and the open sores.  I had to wear band aids on my face to hide the sores and it was very uncomfortable.  However, within 3-4 months, I received numerous comments about my skin and how healthy it looked.  

I applied a second dose a year ago to isolated areas and did not have any of the severe issues from the first time.  My dermatologist recommended stopping the treatment at the first sign of open sores or major irritation, but I never had to follow that advice.  Although the first application results were extreme and unexpected, I am glad that I did it."