bacterial skin infection
"First and foremost I want to let you all know, reading things on the internet, WILL NOT help, nor really be a good indicator of your personal reaction to any drug. There are many negative reviews here for Bactrim, and I'm on day 3 of a 10 day dose for a staph infection (cellulitis) on, of all places the right side of my face/right ear (its wonderful!). Here's my experience:

Side Effects: Fatigue, headaches (though not consistent). I have a weaker stomach, and its doing just fine with my probiotic (get one with 30billion strands) and drinking lots of water/eating while taking it. 

The infection is clearing up. Day 3 was when I really noticed. 

Don't be anxious when taking this, its definitely a mind over matter thing sometimes too."