depression
"I have been off and on antidepressants for years.  I finally got to the point with being on bupropion 150mg for over two years but my depression kept worsening.  My doctor finally changed my prescription to bupropion xl300mg and my life has drastically changed.  I have so much more energy now.  Before I just wanted to sleep all day.  Now, I am up and active all day and actually want to take better care of myself and my home/family.  It's been amazing -- add in my 24 pound weight loss so far in four months and I'm finally looking forward to my future!  My major side effects that bother me are dry mouth and ringing in my ears.  I also notice that my PMS has worsened, but the positives definitely outweigh the negatives!"