multiple sclerosis
"I too have MS and have been taking this drug since it came out - about 6 years. Because Provigil is not an amphetamine it doesn't make you "high", you just feel like you have energy.  Provigil does not interfere with your normal sleeping pattern, if you take it in the morning.  I feel like my old self when I take it.  I also know now when I do not take it (I'm on 200mg). I can feel the difference, what I thought was depression was actually a lack of energy."