depression
"I have severe depression and general anxiety disorder.  I take 100mg/day of Zoloft, and that pretty well takes care of my depression, and most of my panic attacks.  Occasionally, I'll take 0.25mg for a panic attack, but I'm cautious because sometimes the downside of coming off a panic attack sends me into a fit of depression.  I highly recommend both Zoloft and Xanax, I just want to put the word out there to use good judgement when treating a panic attack when you have depression as well."