back pain
"Significan Arthritis at L4,5, and S1 with no surgical options.  Muscle spasms that will put me on my knees and I'm over six feet tall; long way to fall.

I've been on 10/325 for about five years; that's a long time.  I take ONE a day usually late afternoon.  Typically I get a little drowsy but can work through any residual pain until bed time.  Oh, I've also got two artificial knees thanks to my service in the US Navy.  And this stuff works on the pain from them too.  Yes, artificial knees can still hurt you.

I'd prefer to have the back pain dealt with at it's source rather than it's symptoms, but to date, no one has any idea about how to do that.  Until then, I keep a bottle of pain killers near by."