ovarian cysts
"I have polycystic ovarian cysts. I used to be on Tri-Sprintec, the polyphasic version of this pill, and had the worst headaches from the hormone changes every week.  Switching to Sprintec seems to have solved the issue.  My acne and hair issues, courtesy of PCOS, have improved, and I feel better overall.  I did gain about three pounds, but I started the medication shortly before the holiday season so it could have been a product of too many parties.  Definitely worth a try if you need a higher estrogen level pill.  Plus, it's affordable even without insurance."