diabetic kidney disease
"I was initially prescribed ramipril for renal protective purposes due to high proteinuria.  I started at 5 mg and was gradually increased to 30mg over a 2 year period. 
Side effects: sleeplessness, irritable, panic attacks, overwhelm, inability to cope with everyday life, crying, loss of confidence, unable to complete projects... 
I thought is circumstantial, so over 6 month period quit my jobs and focused to reduce and manage stressors in life. But no improvement!?! The only thing left to remove/try was the drug. I went off it for 12 days and felt like million bucks! Calm, happy disposition, sleep, I was myself again! But bp went up to 189/116.  Hope there is another option for me :("