depression
"I am on my third day of taking 50mg of Pristiq after 12 years of taking 150mg of EffexorXR every morning. I have had my depression and anxiety under control for the last 11 1/2 years because of therapy, family support and the EffexorXR. My main reason for trying Pristiq, which is very similar to Effexor, is to try to lessen the amount of time it takes to achieve orgasm. "It takes forever!" My doctor seems to think this will help. We'll see."