epilepsy
"I have been on Depakote for 13 years after I had 2 grand mal seizures in one year. After being placed on the Depakote delayed release I have been fine ever since, there was a time that I tried the extended release and my legs started to show some spikes so I switched back to be on the safe side which was the better call. I also use the sprinkles. As for the weight gain I never really gained more than about ten pounds but I stay active and mainly keep it off, my doctor also put me on Topamax which helps balance out the weight gain because Topamax makes you lose weight and Depakote makes you gain so they both kind of cancel each other out. Topamax also helps with seizures so it was an addition, and I have been seizure free for 13 years."