pain
"I had a spinal fusion that didn't fuse, 3 spinal surgeries total, broke hip, broke leg, several more bad discs in back. Opana is the only medicine that actually relieves the pain without the bad side effects. Take Opana 30 every 12 hours (twice daily), with Opana IR 10s in between. Doctor gives me 3 10s per day.   

Best medicine on the market as far as I know.   I can work and function now, where before I could barely get out of bed.   It is expensive, but so far insurance covers all but $100 per script per month.   High, yes, but worth it."