depression
"I have suffered from depression on & off since childhood as I had gone through a lot of trauma in my childhood. I believe my brain was rewired due to the depression I've endured since - that first started when I was 9 yrs old. I've been on about 14 different antidepressants of all types (including MAOI 's & mood stabilizers & none of them had really worked for me. I gave up on everything - & truly believed I'd just had to accept wanting to die almost daily for the rest of my life!!! I finally asked my Dr. if I could try any new antidepressants & he prescribed Pristiq. 
This is the start of my 3rd month on it & it's changed my life! I'm actually feeling wonderful & have found hope again! On 50mgs/day."