depression
"I have had some level of depression for decades.  Also have some form of anxiety I have never understood as to why, PG calls it social anxiety. After being prescribed a series of anti-depressants for years I landed on Venlafaxine and have been taking it for 20 years 150 mg by GP  Tried to stop gradually as GP required but found I must need it due to a chemical imbalance rather than a life situation.  Only one minor side effect is dizziness. Can avoid this by eating something and drinking a full glass of water when taking it.  Drink minimum 6-8 glasses of water a day, more if needed as this will also alleviate dizziness.  I don't know how helpful it would be if my life fell apart completely.  But it has worked fine for me all these years."