psoriatic arthritis
"I was on Remicade infusion for 7 years,  I had wonderful results for 6 years, with PSA flares slowly creeping back in the 7th, but not unmanageable.  Rheumy switched me to Simponi.  After 2 injections, while my skin is still clear, the PSA is raging.  I am in terrible pain.  I spoke the my Rheumy once and she said to give it a chance.  Calling her again this morning.  The pain and exhaustion is debilitating and affecting every aspect of my life.
I asked he about Taltz and Cosentyx but she wanted to keep me on a TNF blocker.  I'm ready for change."