osteoarthritis
"I took 200mg 1 per day, for osteoarthritis in my hands. The pain relief was amazing. I could sleep through the night, and wake rested, and was thrilled to have nearly pain free use of my hands. After 1 week I began to develop an irregular heartbeat. First day, it wasn't too noticeable, and I was able to ignore the feeling. The irregularity increased, that night it was difficult to sleep. Next day I spoke to the doctor who did an EKG. He said I was having  Premature Ventricular Contractions (PVC). He advised I stop taking the Celebrex immediately. It took 4 days for the PVCs to subside. After waiting 2 weeks, I tried taking Celebrex again. After 3 days, the PVCs returned. Stopped the medicine, PVCs stopped. "