depression
"I took Nardil for 21 years.  It worked better than anything else, until the dose was increased from 10 to 40 mg per day.  None of my physicians were able to diagnose the cause of the grotesque swelling of my legs.  A friend suggested it might be the Nardil; I quit taking it and proved her right.  Even in reduced doses, the swelling persisted.  I now take something else."