rheumatoid arthritis
"On Humira approx 4-5 yrs now.  I understand the risk of your immune system being compromised however the relief I receive outweighs in my mind that risk.  I am overall a healthy and active individual.  I'm 56.  I take Methotrexate in combination with the Humira.  Early January 2015 I had a knee replacement.  Successful surgery.  I needed to be off the Humira for more than 2 months due to that.  during that time I had major flareups.  I've been injecting again with the humira pen ,  3x in 3 weeks...it's not yet working again....Has anyone experienced this being off of it for a few months and then starting up and the humira being non-effective?  I'd be interested to know.  I'm at the point to ask my Rheum what gives?  Diff treatment options?"