birth control
"I have been on a variety of birth control pills for 15 years now, and Junel is by far the worst medication I have ever experienced.  Immediately I experienced severe mood swings and depression.  I stayed on Junel for 2 months, but nothing ever improved.  3 years later, a new doctor accidentally prescribed Junel to me, and I decided to try it again.  Again, immediate mood swings, depression, etc.  "