acne
"I took Roaccutane 9 years ago at the age of 30. Although I didn't have cystic acne, I had had persistent facial acne since the age of 12, and nothing helped. Initially the drug helped a lot, with the major side effect being severely chapped lips and dry skin. After several months of treatment my dose was increased. Within days I was depressed and miserable, with crying spells. It took me a while to put 2 and 2 together and consider the medicine as a likely cause. I dropped the dose down again and I quickly improved. However, I feel the damage was done and I gradually became more and more depressed and ultimately was taken of the medicine. For the past 9 years I have suffered depression and anorexia nervosa."