depression
"Another poster said that Sertraline made her a better person.  That's really true for me. I wish I had started taking it years ago.  I don't get the full benefit with less than 100mg per day. Unfortunately, I have to stop taking Sertraline as I have a worsening spinal condition and I have to take NSAIDs (ibuprofen) for pain control.  When I take the two drugs together I bruise so easily that I worry about more serious bleeding.  For me, Sertraline has also reduced my libido.  I'm a male in my 60s but I'm not yet ready to give up on sex, nor is my wife."