postmenopausal symptoms
""My body does not like this ring - it is quite hard, large, and terribly uncomfortable, paid $100 for it, WITH insurance. Estradiol acetate, which is the kind of estradiol provided in this ring, has to pass through the liver, which is an inefficient way for the body to absorb." 



In reference to the second reviewer, Femring is a transdermal estrogen and it does not have first pass metabolism through the liver. Only oral estrogens do that. It also is not hard and if placed at the top of a normal vagina (which expands - a hysterectomy cut vagina does not do as well), you won't know it is there. I have personally used this for over 10 years and have prescribed it to 100s of patients. Over 90% loved it - except for the cost."