ibromyalgia
"Suffered excruciating lower back pain and was taking Vicodin 2-3 x's daily for my Fibromyalgia. I've been on Pristiq for about 3 weeks. 

Pain has diminished 98-99%. (Sometimes feeling 100% relief. However, miracles I don't expect.) Only on occasion did I take a Vicodin (and on that day only 1x). This was only due to lower back discomfort I didn't want to deal with, but not excruciating pain!"