migraine
"I take Rizatriptan in conjunction with ever-changing migraine prevention meds. It makes my sinuses feel drained and parched, makes me woozy and slow in the brain, and tastes absolutely terrible.  But? If I take it at just the right time in the onset of a migraine, it is usually able to knock it out within an hour or two.  If it doesn't--if I'm too late to take it--it can't kill the migraine, but it does dull it enough that I can usually continue functioning.  Acts faster for me than Sumatriptan did.

Only giving it an 8 because you do have to take it at just the right time, and you can only take 2 in a day.  I sometimes get the back-to-back migraines and am helpless to fight the 2nd one."