bipolar disorde
"I was prescribed 250 mg, but to take three times a day (every 8 hours).  I don't think that's really too high.  Perhaps it's because I was on such high doses of other things in my past--who knows.  So, to me, my body is used to truly high doses of such medicines.  Either way, 250mg of Depakote DR is the lowest you can be given, and that will only carry you through part of the day.  This is why the doctor has to make you take it three times a day.

I haven't had practically any side effects, except for a little "wet noodly" feeling, but none of the side effects (yet) that are listed.  Guess it's different for everyone."