depression
"I have been on Zoloft several times. The only side effect was the "runs" which is fine you can take anti-diarrhea medication.  I am also on Epilim, I was recently diagnosed with Bipolar which in itself is a good thing.  No antidepressant worked for me, I was always low.  And off them I was both hyper and low.  It was horrible, then the anxiety kicked in.  So that's why I am glad to be finally diagnosed as at least I can get help and proper treatment.  Zoloft is brilliant for anxiety, but it didn't stop the bad lows and I was so tired. But no side effects whatsoever, well only the runs - which you learn to live with."