major depressive disorde
"Love, love, love this drug. Spent seven months in total depression and attempted suicides.  Tried four other antidepressants which didn't help. Effexor saved my life literally. Started working within 3 days at a dose of 300mg. I'm now happy, not anxious, not depressed, not suicidal. I'm back to being me.   No nausea or major side effects, apart from low libido which is common for this class of medication and insomnia.  Works for those who genuinely need serotonin to be be restored to their brain.  Worth a shot, if other medications have failed."