obesity
"I've been taking Qsymia for 6 days now, and I feel the random tingling feeling and numbness, with that being said, I've lost about 4 pounds so far without changes to my lifestyle. Foods do taste different. Sodas taste like metal, rice and bread taste like cardboard, and anything other than a salad, lean grilled, broiled or steamed meats or fruits taste rather nasty. 
One thing is for sure, AVOID ANY DRINK WITH ASPARTAME IN IT, it will give you a monster headache and really make the tingling numb feeling really noticeable. I thought I was going to die...my head and my eyes hurt so bad. Dropped the sparkling flavored water, and diet sodas, and feeling awesome. Will update in a few weeks with progress!"