obesity
"I was prescribed topiramate for daily post-concussive headaches, and I also needed to lose weight.  The first three weeks were really rough, and I was unsure if I could take this medicine long-term.  I started off with 25mg the first week, 50mg the second, 75mg the third, then 100mg as my permanent dose.  I took it before bedtime as instructed, but I had next day drowsiness so bad that for three weeks I felt like I was going to face plant at any moment.  Also, the nausea was so bad that I barely ate.  Thankfully, both of these side effects stopped after about 3 weeks as did most of my headaches.  I've also lost 22 lbs in 2 months.  The best part is that it has given me control back in that I eat smart and don't have unhealthy cravings."