high blood pressure
"I have limited experience with any other Blood Pressure medications but reading the comments I see the patterns I've experienced on Bystolic (10mg before bed every night).  Intermittent restless sleep, occasional neck and shoulder pains, inconsistent blood pressure readings ranging from an ideal 120/80 to spikes around 160/100. Intermittent bouts of extreme fatigue. I think my problem might be either inconsistent dose effectiveness (i.e. some of my pills might not be as strong as they're supposed to be) or I need to be on smaller doses twice a day to even out the effects. I'll check with my doctor."