hepatic encephalopathy
"I had taken Lactulose for almost 5 yrs before Xifaxan came out.  I had a lot of diarrhea and general bloating and abdominal discomfort with Lactulose.  That all disappeared when I started Xifaxan, and I would encourage patients to do themselves a favor and improve their quality of life by asking their doc for Xifaxan.  My ammonia is  <25, better than when I took Lactulose, and my feeling of well-being is 10 out of 10."