depression
"I've been on Brintellix for 4  months now.  It is providing a mild antidepressant/anti-anxiety effect, but definitely not robust enough for my lifelong generalized anxiety disorder and depression.  I'd give a 3.5/10.  It's better for me than Viibryd (the medicine it most closely resembles), but I'm still in a state of deep dysfunction.  On the positive side, the side effects have been minimal, the most prominent being some decrease in sexual desire and sexual pleasure.  (Not really an issue for me though since my anxiety and depression pretty much have a corner on that non-existent aspect of my life).  Also, even with my decent insurance, and Takeda's "discount card," the cost for a month's supply of 30mg a day (the dose I'm taking) is about $300.  Not affordable."