depression
"I have been depressed most of my life and especially during my menstrual cycle.  I have taken Zoloft to start with, Effexor, Paxil, Prozac and finally Cymbalta.  When I started taking Cymbalta I had such heart palpatations and other bad side effects, but I thought I'm going to take this even if it kills me, better it, than me killing myself!  So I stayed with Cymbalta and I don't think I could live without it now.  It has taken care of my severe depression and anxiety problems.  You have to give it a chance.   "