irritable bowel syndrome
"I'm a woman who's had IBS for 50 years. A male GI was no help—his notes said I was "too concerned with my bowel movements". Apparently a skeptic about IBS. I saw a PA, who prescribed Amitiza. I took 24 mcg 2x daily more than a year, which worked well until I started having episodes of thin diarrhea without warning. I discontinued Amitiza and my bowels worked normally for a couple of months, but the old familiar constipation is back. I will try 24 mcg once a day. I have no idea if that will work, and realize that my PA would prefer monitoring me. However, I feel at this point that I have enough sense about my own body to make this decision myself. Just be aware: even if the drug works well, your response to it may change."