pain
"I take 50 milligrams of indomethacin with a caffeine tab at first sign of migraine and call it quits until relief kicks in in about 1 1/2 hours.  Slower than Imitrex but much cheaper and not limited by insurance.  My headaches have signs of autonomic nervous system dysfunction, common to indomethacin sensitive headaches so my neuro suggested a trial dose taken daily along with Topamax for a preventative.  When I took indomethacin daily I got mentally weird and even paranoid and anxious which was totally not me so I quit daily use and only take it with individual headaches."