multiple sclerosis
"I am very disappointed.  I had tried Ampyra about 3 years ago and found no effects at all.  At the urging of my neurologist, I tried again this year. For symptoms, I am taking Provigil & Baclofen.

I take Copaxone as a disease modifying agent.  Previous to restarting Ampyra, I was doing 1/4 mile on a treadmill 3 times per day plus one mile on the elliptical at night. My legs felt very heavy on the first day of Ampyra.  I might have done just one rep on the treadmill. I thought possibly that my body was adjusting to the medicine, so I gave it about one week. I found it difficult to do my daily treadmill.

Legs also were throbbing slightly at the end of the day.  This medicine had a negative effect. I am out a $300 copay."