narcolepsy
"I treated narcolepsy first with Nuvigil then Provigil.  Having Lyme disease compounds fatigue and pain on top of sleepiness.  I maxed out at 200 mg provigil bid and it became ineffective.  I take Ritalin 20 mg TID.  I am no longer fatigued, in pain or sleepy.  I have a high tolerance to drugs and not anxious to up my dose, but really need 4 times a day.  My only side effects are compulsively picking the skin around my fingers and compulsively drinking chocolate milk.  But I no longer feel a wet, wool blanket of fatigue, pain and sleepiness over me.  I also tend to hyper focus.  I'm a natural scholar so that's ok by me, but I will study one topic for 8 hours compulsively.  Yeah, compulsion is the only issue I have with it."