ibromyalgia
"Started Savella on 5/30/10 2-week titration pack.  First 2 days took it morning and evening, but could not sleep even with Ambien.  Stopped the evening dose and took Ambien only when had trouble falling asleep, and able to sleep again.  Biggest problem was daytime sleepiness - very difficult to deal with.  I am at 50 mg./day, morning only.  It helps with the daytime sleepiness very well, and with some of the aches and pains.  50 mg gives me mild anxiety which is hard to take. Will go back to 25 mg.  If you can't sleep-don't take it at night.  Keep your room cool/cold.  "