underactive thyroid
"Synthroid by itself was not effective.  It is of great interest to me that so many other people have had the experience of being told by a physician that everything is fine while everything was, decidedly, NOT FINE!  (making long story short due to length restriction. Details need space.)  Large dosage of Synthroid ineffective, nurse practitioner certain nothing wrong, physician A dosage is ok but maybe a small bump, small effect for short period then return to prebump effect, concerned that observation due to psychological rather than physiological waited, physician B does further workup, physician B sees most of Syntroid dosage going to reverse T3 (physiologically ineffective) adds Cytomel, the improvement was immediate; not psych."