gout
"I experienced attacks of gout from my 20's on - debilitating pain in a foot joint being the most common symptom. I'd have half a dozen attacks of this per year lasting a few days.

I finally went to a doctor in my early 30's and was put on a daily Allopurinol regime, and I haven't had an attack since.  I'm currently in my mid 60's.

Over the past 6 years I've significantly altered my lifestyle, dropped 60 lbs, exercise far more often, and no longer eat meat, so I'm considering asking my doctor if I should try going off the medication.  But overall, it has been a blessing to me."