Figure 2. Elongated mitochondrial morphology in neurons overexpressing Bcl-xL and dnDrp1K38A. (A) Fluorescent microscopy images of rat cortical neuron processes 1 d after transfection with mito-RFP (and mtPA-GFP) plus the indicated constructs or empty vector control. (B) Data from 96–131 mitochondria in four independent experiments as shown in A were quantified and presented as mean ± SEM. All six paired comparisons are statistically different (p < 0.001) except dnDrp1 versus Bcl-xL + dnDrp1 (marked with an X). See “Computational methods” and Table S1 (available at http://www.jcb.org/cgi/content/full/jcb.200809060/DC1).