 de novo sequencing is a popular technique in proteomics 
 for identifying peptides from tandem mass spectra without having to 
 rely on a protein sequence database . despite the strong potential 
 of de novo sequencing algorithms , 
 their adoption 
 threshold remains quite high . 
 we here present a user - friendly and 
 lightweight graphical user interface called denovogui for running 
 parallelized versions of the freely available de novo sequencing software pepnovo+ , greatly simplifying the use of de novo sequencing in proteomics . 
 our platform - independent 
 software is freely available under the permissible apache2 open source 
 license . 
 source code , binaries , and additional documentation are available 
 at http://denovogui.googlecode.com . 
Supplementary Material