Is Naruto related to Hashirama Senju? Hashirama Senju, the 1st Hokage, married Mito Uzumaki right? So does that make him Naruto's great, great, great grandfather?
Well, both Naruto and Hashirama Senju are reincarnations of Asura. Apart from that, Hashirama could not be Naruto's direct descendant as marrying to Mito Uzumaki does not mean Mito Uzumaki is directly related to Kushina. There might be a slight chance, but the possibilities are endless, assuming the Uzumaki clan is a big clan.