Do we know what Hana is sick with? In Tokyo Godfathers, we know that Hana is sick. She's shown coughing up blood several times and ends up in the hospital at one point in the movie. It's not clear to me what it is that she's sick with. I wasn't paying attention to all the details, so it could have been said, or this could have just never been revealed.

Do we know what sickness was afflicting Hana?
It is never revealed outright but it is implied to be AIDS. We know that Hana used to have a boyfriend named Ken who died (and caused Hana to drift away from the drag queen club). When asked if Ken died of AIDS, Hana glibly replies "No, he slipped on the soap". So the implication is that Ken did die of AIDS and probably passed it on to Hana.