rendering with the video card in MeGUI I do not know this is the right forum to ask for help.

I need help to speed up rendering with the software MeGUI 2500.

First I render to premiere with the help of CUDA.
CUDA makes the video card also yield, speeding too.

I put the second video has already ended in MeGUI 2500 with AVS scriptcreator decrease the size without affecting the quality too. Only in this software (MeGUI) did not find how to enable the video card to render.

If you have no way someone could tell me other compression software that helps with the video card? Why premiere is not very good at it.
If I understand you correctly, it sounds like you are trying to find a piece of software that can use hardware acceleration to encode video generated by AVISynth.  If that's the case, I'd suggest looking at Handbrake, which is capable of utilizing GPU acceleration and should handle AVISynth sources just fine.