Help with composition of a movie shot - direction of character's eyes I am making an animated short and I need help to decide the right direction of the character's gaze.

On the image - 

The uppermost shot is the preceding frame - the Red is standing over Blue, and looking down. He is slightly to the left of him (the axis of the camera is on the right side of Red)

The last shot is the following frame - Red is leaving and the camera stays on the right side of the axis.

Where I need help deciding is the case 1) or 2).

The 1) is feeling more natural to me, Red is looking to the right side, which the Blue occupies in other frames.

But case n.2 makes more sense, as Red is looking down and to his right, where Blue realistically is in the scene. 

I am not sure which one to use.
Shot 1 makes the most sense. In shot 1, your camera doesn't "cross the line" between the two characters. (That's an important cinematography rule; audiences unconsciously expect it.) Here's the easy way to apply this rule to a scene with 2 characters:

The character on the left of the frame in the wide shot should always be looking towards the right of the frame, and should keep looking towards the right of the frame in close ups and over-the-shoulder shots. (The opposite applies to the other character.)

Your character in red starts out on the left of the frame, and is facing the right of the frame (even though we see the back of his head). He needs to keep looking towards the right of the frame in subsequent shots in that scene. Shot 1 shows him looking towards the right of the frame, so that's the shot to use. :)