Homebrew R vs Microsoft R I understand that math library integration is the main tweak that sets MRO apart from the CRAN R distribution, and gives it a performance advantage. 

I wonder if MRO (Microsoft R Open) binaries still have a performance advantage over Homebrew R, given that both Homebrew R and Microsoft R link their binaries against Accelerate (MKL) math libraries in macOS.
In my experience MRO is faster when using data.table and large datasets.

However, in Ubuntu, OS X, etc I found more convenient to use CRAN version and compile everything to avoid crashes, crossed wires, etc.