Mac Mini won't wake after sleep with Mountain Lion I have a late 2012 Mac Mini with Mountain Lion installed.  I have had the Mini for around 6 weeks and am using as a media server.

When the Mini goes to sleep (either automatically or by manually telling it to) it refuses to wake up.  The power light is pulsing.

The Mini is connected via HDMI to a home cinema receiver (which is in turn connected to a TV) and has an external USB hard disc and USB hub attached.  There is a wireless keyboard and mouse attached via USB also.

In the Energy Saving preferences I have all tick boxes enabled apart from "put hard discs to sleep".  I have tried the wireless keyboard, mouse and the Apple Remote app to wake the Mini to no avail.

Any ideas?  I really need it to sleep and wake when needed as thats an essential feature of a media server.
Try resetting the NVRAM / PRAM as noted About NVRAM and PRAM


  Resetting NVRAM / PRAM
  
  
  Shut down your Mac.
  Locate the following keys on the keyboard: Command (⌘), Option, P, and R. You will need to hold these keys down simultaneously in step 4.
  Turn on the computer.
  Press and hold the Command-Option-P-R keys before the gray screen appears.
  Hold the keys down until the computer restarts and you hear the startup sound for the second time.
  Release the keys.
  


See if the sleep problem still occurs, if it does try resetting the SMC as noted Intel-based Macs: Resetting the System Management Controller (SMC).


  Resetting the SMC for Mac Pro, Intel-based iMac, Intel-based Mac mini, or Intel-based Xserve
  
  
  Shut down the computer.
  Unplug the computer's power cord.
  Wait fifteen seconds.
  Attach the computer's power cord.
  Wait five seconds, then press the power button to turn on the computer.
  


If the problem still persists and you are running OS X Mountain Lion version 10.8.2, there may be a sleep bug that is effecting the reliability of sleep on a lot of Macs as discussed Problem with waking from sleep with 10.8.2 


  My Mac Pro (early 2009 2.66 GHz Quad-Core Intel Xeon) won't wake from deep sleep after installing OS X 10.8.2 . I have the default setting set for sleep. The only way to "wake" the machine is to hold the power button down to shut down and then restart. I've reset NVRAM (pram) and tried removing power cable. Nothing helps.


Since your Mac Mini is very new I would also consider contacting Apple Support and see what they offer as a solution and at the least notify them of the issue, I am sure they are working on a fix probably scheduled to be included with the next OS X update.