Can I create a keyboard shortcut to lock a file in Finder? I'm constantly opening Info panes so that I can lock the currently selected files in Finder. Keeping the Info pane open is no longer good enough; it gets cumbersome to manage with multiple desktops and screens.

Can I assign a keyboard shortcut to do this?
Keyboard Maestro can do this with a macro such as this, which will run chflags uchg on every file in the current Finder selection: