Can I simulate multi-touch input on a Mac? With iOS's accessibility features, it is possible to pretend the user is using multiple fingers or making certain gestures while in reality they are only using one finger.

Is there any way I can simulate multi-touch trackpad gestures on a Mac?

(Note: While this can be used for accessibility purposes, I'm specifically thinking of using this to two-finger-scroll while using my Monoprice drawing tablet. An answer that fulfills that function without working in all circumstances will also be accepted.)
BetterTouchTool lets you create custom gestures, with custom actions. There are a variety of single-finger gestures: 

 

Have a look at it, and see if it suits your need.