How can I get Safari 5.1 to show the download window? I know that I can simply click the downloads icon next to the search bar, however I'm visually impaired and have trouble using the mouse (I can't find it, miss click), therefore I'm much faster with the keyboard.

I'm wondering how I can show and focus the downloads manager in Safari 5.1 just like in prior versions.
Or you could follow the advice of Red Sweater^1 and use AppleScript + FastScript/Sparkle. If you follow the link everything is explained in details.