iOS: block ads in Apps without Jailbreak and VPN tunnel (normal 3G/4G network) For example in RT app there are annoying ads. There is no way to pay subscription without ads.

Howto block ads in Apps (in Mobile Safari I block them all)? I found only apps that offer a VPN tunnel (you need 100% to trust them) and solutions for iPhones with Jailbreak. Are there other possibilities?
No, because apps aren't able to inject themselves into other apps without jailbreaking, they are only able to use Safari Content Blockers in Safari or routing network traffic through a VPN.