"Save-as" shortcut not working for anything For all of my apps, the command+shift+s shortcut is not doing its expected "save as" function.  I am assuming there is a conflict somewhere, but when I go to preferences -> keyboard -> shortcuts, there are no conflicts that I can find.  This is driving me nuts... any thoughts? 

I'm on El Cap 10.11.3 / MBP 15 (2015 model)
Follow this guide, you'll be able to track down a few more places that may be interfering.


System Preferences -> Keyboard -> Shortcuts


This is the obvious one that you'd think of. However, you said you've checked and can't find anything, so we'll move on

System Preferences -> Dictation and Speech -> Text to Speech


It's unlikely, but possible that you bound "Speak selected text when the key is pressed" to something else (as I have.)

~/Library/Preferences/com.apple.symbolichotkeys.plist


If you can't find anything else take a look here and see if you spot anything that's using the keys you want unbound.