Does Parrallel win 10 work well for Macbook 12" 2016? Does Parrallel win 10 work well for Macbook 12" 2016 ? I am going to buy new MacBook 12" as it is so cool. However, I need to use Microsoft Office 365 for my work with full compability.
Yes. Parallels will work with any reasonably new Mac with relatively little performance hit. It uses virtualization technology, and should suit your needs.

With that said, MS Office 365 is compatible with OS X, so I'm not sure why you'd need to use a VM at all.