How to create a bootable Windows 10 USB with a Mac to boot/install on a PC? I have no access to a Windows machine at the moment, but need to create a bootable Windows 10 USB stick from a Mac that can be used to boot and install on a PC (not a Mac).

Microsoft provides the ISO file 

Can I just copy that ISO file to the USB and boot to it? I would use the Media Creation Tool, but you can't if you're on OS X.

For reference, my Mac is on High Sierra.
You can try "MS-DOS FAT" formatting with "Master Boot Record" scheme a flash drive. Next mount the download of the current version of Windows 10. Copy all the files from the mounted ISO to the flash drive. Try booting on a Windows machine.

If this does not work, then you could install VirtualBox. This is a free product. You can install Windows as a virtual machine, then use the Media Creation Tool to create the flash drive.