How to disable macOS catching CTRL-A when running screen I am connecting to a Linux computer through the serial port using screen on my Mac.

I ran minicom on my Linux computer and minicom uses CTRL-A for commands.

But if I enter CTRL-A, the macOS catches this and tries to interpret the command.  Is there a way to temporarily disable the macOS from interpreting the CTRL-A?
CTRL-A is used by screen to initiate a command sequence. You can either press CTRL-Aa  to send CTRL-A to the other computer or redefine it with the -e option (see man screen for details).