How can I open new Chrome window with different arguments? I want to have a new Chrome window with same origin policy (CORS) disabled for development, while keeping the existing one open for browsing. I already have tried the CORS plugin but it does not work for local files.

Apparently, this can be done on Windows. Can it be done on OSX (10.8) ?
nohup /Applications/Google\ Chrome.app/Contents/MacOS/Google\ Chrome --disable-web-security 2&gt;&amp;1 &amp;


nohup lets you quit Terminal without killing the process.
Arguments are added as normal before the 2&gt;… redirection.

Alternatively, you can try:

open /Applications/Google\ Chrome.app --args --disable-web-security