Safe key combinations for global shortcuts Is there any combination of modifier keys that could be considered 'safe' for setting global shortcuts with a third-party app? For example, I do window snapping with cmdoptJ|L, but cmdoptI would conflict with Chrome's dev tools shortcut. 

I'd like a set of modifiers I can use for virtually any global shortcut I want without conflict.
For personal macros, I usually simply use the control key—practically nothing uses just the control key as a modifier; it's always paired with command. (e.g. ⌃J/L)

If you're asking so you can include it in software you're developing to widely distribute, though, I wouldn't recommend this for exactly the reason that it's a good idea for personal use: it's pretty non-standard.