Safari is using too much RAM. How can I reduce its memory footprint? I'm finding Safari (Latest - v5.0.2) to be even more of a memory hog than usual.  (Currently using 465mb of RAM with only this tab open, but having been running for a while)  

Closing it and reopening it lowers it's memory footprint, but it always creeps back up over time.

Aside from disabling extensions, any tips to help troubleshoot/reduce it's memory usage?  I've been using ClickToFlash which helps by requiring any Flash entity to be manually enabled on each page view.
So it appears that Flash is still the main culprit - if you enable any flash in ClickToFlash it stays resident in memory.

Following Gruber's advice on Daring Fireball, I've disabled Flash entirely on all browsers except Chrome and this seems to have helped immensely