Microsoft SQL Server on Mac Has anybody successfully been able to run Microsoft SQL Server using Wine or another application like it (possibly Crossover) on macOS Sierra?
The best way to find out is look at the Crossover web site listing if each app is supported by Crossover which is the purchaseable version of Wine.  

For SQL Server the answer is no - I think it won't even install.

So try running Windows in a Virtual Machine to run it or use another RDMS like Postgres or SQLite. An easy way to use a VM is to run Docker for macOS it includes (and hides a VM running Linux, Microsoft provide a Docker image for SQL Server with instructions for macOs