Why Can't I Read /private/var/db/ConfigurationProfiles/Store under macOS 10.13 I'm trying to set up a new backup utility on my system, and am getting an error that it cannot get the files in folder /private/var/db/ConfigurationProfiles under macOS 10.13.3.

I don't get the issue under a VM running macOS 10.12 - but if I attempt to read /private/var/db/ConfigurationProfiles/Store, then I get errors:

ComputerName:~ root# cd /private/var/db/ConfigurationProfiles/
ComputerName:ConfigurationProfiles root# ls
.cloudConfigNoActivationRecord
.noActivationRecord
Settings
Setup
Store
com.apple.ManagedClient.enrollagent.plist
ComputerName:ConfigurationProfiles root# cd Store 
-sh: cd: Store: Not a directory
ComputerName:ConfigurationProfiles root# ls -lah
ls: Store: Operation not permitted
total 0
drwxr-xr-x    8 root  wheel   256B 25 Jan 07:51 .
drwxr-xr-x  108 root  wheel   3.4K 14 Feb 12:57 ..
-rw-r--r--    1 root  wheel     0B 13 Dec  2015 .cloudConfigNoActivationRecord
-rw-r--r--    1 root  wheel     0B 17 Dec  2014 .noActivationRecord
drwxr-xr-x@   4 root  wheel   128B 25 Jan 07:51 Settings
drwx------    3 root  wheel    96B 15 Feb 22:17 Setup
-rw-r--r--    1 root  wheel   490B  9 Sep  2014 com.apple.ManagedClient.enrollagent.plist


Getting info on the file in the Finder show unknown permissions:



I've tried the same in a VM running a macOS 10.13 Beta (so, a completely separate installation), and I get the same issue.

Any ideas what's going on here, if I need to correct it, or if I just need to exclude this path from my backups?

Thanks!
Yeah definitely is protected by system integrity protection. Disabling it properly shows the file as a directory. Mine had one blank .plist in it.