Back up different folders to different drives In Time Machine one can back up to several drives at the same time. It is also possible to control which folders are backed up and which are not. However, it seems to me that the same folders have to be backed up to all drives.

Is it possible to exclude a folder from being backed up to one drive, while including it in the backup to another drive?

I use OS X 10.10.1.
I also believe Time Machine's GUI is not able to do that.
But if you feel like fiddling in CLI from terminal, and do some basic scripting, it can be done quite easily using the tmutil command:


tmutil addexclusion and tmutil removeexclusion would allow to change your exclusion list by script whenever you want.
tmutil startbackup -destination would allow to trigger a backup by script to the desired destination, at the appropriate time (what about just after you changed your exclusion list? ;)  )
script scheduling could be done using launchctl (or with a basic crontab job)


Of course, you should disable Time Machine in the Preference Pane, in order to prevent it from starting automatically while your scripted backup may be already running.

Bottom line, have a look at man tmutil. Backups would still be plain standard TimeMachine backups, just triggered differently. Restore could be done in GUI as usual.

Of course, if you have no previous experience in terminal mode or scripting, this gonna be a little harder. But if you feel like learning something geeky, this is the time to try (and then ask for help if needed!).  ;-)