Where are drivers installed on the Mac Where are USB serial drivers installed on the Mac? How can I check which drivers are installed, and how do I remove a driver?
Hardware Drivers in OS X are typically in the form of Kernel Extensions and the primary location is /System/Library/Extensions/ however they can also be within an Application Bundle. You can use kextunload to unload a Kernel extension.  To see what Kernel extensions are loaded use the kextstat command in a Terminal.

Have a look at the manual page KEXTUNLOAD(8) and also the Unloading a Kernel Extension with kextunload section in How to Load &amp; Unload Kernel Extensions in OS X, excerpt show below.


  Unloading a Kernel Extension with kextunload
  
  Unloading a kernel extension from OS X is basically the exact same as
  loading a kext, except you’ll use the kextunload utility with sudo as
  follows:

sudo kextunload -b com.apple.driver.ExampleBundle

  
  Or by pointing directly to the kernel extensions path:

sudo kextunload /System/Library/Extensions/ThirdPartyMystery.kext

  
  Again, you can confirm the kernel extension has been unloaded by using
  kextstat and grep, where it should return nothing.