Make the default location for all save and open actions Google Drive File Stream Using macOS Mojave or High Sierra, is there a way to change the default file location for all save and open actions to Google Drive File Stream?

On Windows I would change it in the registry to g:\users\%username%. What is the equivalent on macOS? We are working with HIPAA data and I need to redirect all file activity away from the local computer onto the encrypted, shared platform.
By default, there is no way to do this in Mac OS.

However, you can do it with Default Folder X, an app which is specifically designed to set default open and save folders. (Hence the name.)

It is a great app from a long, long, long-time Mac developer. Highly recommended. Comes with a free 30-day trial.