no pop up when right click There is no pop up menu when I right click. I have set right button to secondary button as in the following picture.

Using ctrl+left click, there is a pop up menu so I can copy/paste selected or do some other tasks.

What I am doing wrong? I am using 10.6.8 on iMac.
If indeed you have a Mighty Mouse as pictured in that screenshot, it's possible that the capitative sensors aren't properly detecting the right click action.

The most common cause of this was still having your left-click finger on the mouse, or resting very close, which I recall confused the sensors a bit. Try right clicking with only one finger touching the mouse and see if that helps. If not, it's possible that it's simply a hardware failure.