Is the pressure in an HPLC system the same throughout? I'm not sure if I'm articulating myself well enough, but here's my problem: I have a current HPLC system, where we typically have backpressure readouts of around 15 MPa. We are looking to get a new HPLC, and the rep said its DAD detector has a maximum pressure of 6 MPa. My questions are:


Is the pressure at the pump outlet the same as the pressure at the column inlet and outlet?
What pressure is actually being shown on the system readout when looking at the pump? (I'm assuming just the pressure at the pump outlet)
Is the pressure at the detector usually significantly less than at the pump outlet?
Assuming everything transfers from one system to our new one, and we end up with the same types of backpressures, will I have issues with this new detector?
I figured this out. The pressure displayed is between pump and column inlet. There's a pressure gradient from the column inlet to the outlet, so the pressure reaching the detector is significantly less than the readout.