Are the best buffers those that are in a 1:1 ratio with its conjugate acid/base? I wanted to comment this, but I don't have enough reputation, so I just made this a question. I know that buffers and their conjugate base/acid must exist in similar amounts for the buffer to be effective, so would the buffer be most effective when the ratio is close to 1:1 (of the buffer and its conjugate acid/base)?

Also I'm confused about how much of a weak base/acid buffers should be. If you have a very weak acid, then wouldn't you have a very strong base. In this case will the buffer be ineffective? So the upshot of this paragraph is asking will buffers still work if you have a very weak acid?
Yes, the best buffers are those that are in a 1:1 ratio with its conjugate acid/base, but in a somewhat indirect way; it's because buffer capacity is maximum when $\mathrm{pH}=\mathrm{p}K_\mathrm{a}$, and for that value of $\mathrm{pH}$, the proportion of the acid/base conjugates is 1:1.

The contribution of an acid/base conjugate pair to buffer capacity is

$\beta_{\ce{HA/A-}} = C_\mathrm{A} \cfrac{10^{-\mathrm{pH}-\mathrm{p}K_\mathrm{a}}}{\left( 10^{-\mathrm{pH}} + 10^{-\mathrm{p}K_\mathrm{a}} \right)^2} \ln{10}$

(For derivation, check this response to another question)

The maximum of buffer capacity is achieved when $\mathrm{pH} = \mathrm{p}K_\mathrm{a}$, and is

$\beta_\mathrm{max}= \cfrac{1}{4} C_\mathrm{A} \ln{10}$

As you deviate from $\mathrm{pH}=\mathrm{p}K_\mathrm{a}$ in either direction, concentrations also deviate from 1:1 (as per Henderson-Hasselbalch) and buffer capacity will fall.

Note that the maximum buffer capacity does not depend on the strength of the acid or base, only on the total concentration of the conjugate system $C_\mathrm{A}=\ce{[HA]}+\ce{[A-]}$.

What $\mathrm{p}K_\mathrm{a}$ will determine is at which $\mathrm{pH}$ value will this maximum buffer capacity be achieved, so you will choose an acid/base pair with a $\mathrm{p}K_\mathrm{a}$ that will allow the system to act as a buffer around the $\mathrm{pH}$ that you want to preserve; ideally by choosing a pair with a $\mathrm{p}K_\mathrm{a}$ equal to the target $\mathrm{pH}$, which is when you will obtain the maximum buffer capacity.