What can be used to thionate a monosubstituted urea? I'm looking to make a thiourea from a monosubstituted urea. I haven't found any references that use Lawesson's Reagent, which I have been using for the thionation of di and trisubstituted ureas. Is there something that would prevent Lawesson's Reagent from working on a monosubstituted urea?
I believe Lawesson's Reagent could do this. It is useful to thionate a large number of carbonyl compounds including amides, so I think it can do for urea as well. I don't see any effect on a monosubstituted urea that would negatively affect the reaction.