Can someone explain the article below? This is the article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611670/
I'm not a Chemist, so I can't understand the article very well.

The conclusion states that the molecules tested should not be called "piezolytes". Is this a nomenclature issue only? My only question is: does the presence of such molecules in deep sea organisms help in keeping proteins in their naturally folded state, resistant to denaturation due to high pressure or not?
From the abstract of the article in question:


  The results suggest that the pressure stability of a protein in solution is not directly affected by the presence of these proposed piezolytes, and so they cannot be granted this distinction.


So the answer is "no", the supposed piezolytes do not appear to have the purported function. They do stabilize proteins against thermal denaturation, but not against pressure-induced destabilization.