How to properly work with potassium HMDS What is the proper procedure for working with KHMDS?  I would like to use it to deprotonate a compound and have a bottle of KHMDS in toluene.  Does it need to be handled under inert atmosphere?  And is it soluble in halogenated solvents?
If you would look up the properties of KHMDS from a chemical supplier, you will find it will react violently with with water. So do keep it under inert atmosphere.

As for solubility, it is a non-nucleophilic base, so probable no substitution and addition like reactions will occur. I wont suspect it will be a problem there.

A comment on the use though. If you plan to use this, explore the dangers and possibilities of a substance like this a bit further than asking it here. For safety considerations. Look up the MSDS sheets from your supplier and be sure to only use this in a properly equipped lab. 

Hope this helped.