How to Proceed By Right Effort I understand and have understood what in Buddhism is linked to right effort, which involves aspiring to what is skillful and abandoning what is unskillful. 

Yet, I wonder:
How do practitioners proceed in terms of order or in terms of determining what to do next? How does one determine what is most important?

Thank you
Not just my own understanding, but a standard teaching is to approach things gradually, from coarse to subtle.

First, we have to stop creating major sources of trouble for ourselves. How do we do that? By following five precepts. Then, we stop creating medium-sized issues, by following the behavioral parts of the Eightfold Path. Then we stop creating subtler types of problems, by learning to control our emotions. Then, we get to subtle problems, by engaging in Samatha meditation to learn to stop compulsory thinking and inner dialog. Then, very subtle problems, by getting rid of egoistic perspectives. Then, ultrasubtle problems, by letting go of attachment to perfection and spirituality. Then extremely ultrasubtle problems, by practicing groundless suchness. These are just examples, you get the idea. 

This is taught in many schools, and by many teachers. One thing at a time, by size, do the bigger stuff first. Stop creating large problems first.