State of mind corrected by anti anxiety or anti depressants How does karma apply itself to an incarnation with a predisposition to aniexty who acts and reacts differently on no anti depressants , to the same incarnation who is not on mind control drugs.
Here are some thoughts on the topic, and i want to be clear that i'm not looking to argue for either of the alternatives of medication/no medication. Also, any question regarding the effects of medicine and the proper ordination has to be consulted with the doctor prescribing the medicine first hand.

If by karma you mean sila/moral consequences of medication, i don't believe a buddhist perspective differs from a layperson perspective on moral. Generally speaking, drugs that affect our actions in a way that risk being harmful to ourselves or others are illegal, and are not prescribed by doctors (I realize this is debatable).

On the other hand, if you're wondering about any form of consequence from a buddhist perspective one could argue that the use of medication is a form of tanha - desire for pleasant feelings, alternatively a desire for eliminating negative feelings - and as such can be a hindrance to develop a buddhist understanding of dependent origination, anatta or anicca, for instance.

However, one may argue that medication really doesn't do any difference to the fact that vedanas/skandhas are continually transforming independent of the choice of medication or no medication. One may very well be able to develop mindfulness and concentration in the buddhist sense either way, provided that the medication (and eventual side effects) doesn't affect your concentration or perception.

The aspects mentioned above regards medication, and could also be weighted against the option to live with unmedicated anxiety or depression, and deal with these things according to the buddhist noble eightfold path. I would argue that this is a matter of severity of symptoms, or the intensity of emotions, and that a buddhist approach to life is easier done in cases of lighter forms of negative emotions or mental illness. Also, the karmic effects of actions based on more severe emotional states of anxiety, depression or illness may very well be more concerning compared to how one goes about ones life with a prescribed and carefully planned medication.