QR Skewer orientation Sheldon Brown's site suggests that QR skewers should be installed with the levers on the left side of the bike, &quot;so the derailer [sic] doesn't interfere with it&quot; and that &quot;Usually, the lever for the front wheel also is on the left side, but some Bike Friday travel bicycles fold more easily if the handle is on the right side&quot;.
Most of my bikes now have disc brakes, and it seems better to install the levers on the right side so that there's no potential of the handle fouling the brake disk, however remote that possibility may be.
If I don't have any problems with the QR lever hitting the derailleur, is there any other downside to installing QR levers on the right side of the bike (drive side)?
https://www.sheldonbrown.com/skewers.html
This is one reason why we keep them on the left.