Best way to patch road bike tubes I've scoured the internet for this answer, as I recently just tried to repair a tube on my Purefix fixed-gear bike which I assume uses tires and tubes similar to road bikes, as the tire size is 700cx28. Anywho, the patch pinched the tube and was no longer usable. I used the pre-glued ones, but the problem seemed to be that the patch pinched the tube. 


Does the type of patch (pre-glued, non-pre-glued) matter a ton?
Should I apply patch to a partially inflated tube or deflated tube?
Does the tire-liner stuff really work in preventing flats?
Are my tires to blame for all my flats?


This is my first time on a bike that isn't a mountain bike, and I've had 3 flats now in 2 months and I haven't been able to patch them. Thanks for all the info guys and gals!
When I make a repair, I also do the following extra steps, to make sure that the patch holds. I have never had a patch come off/leak when using this technique.


Use a little bit of sandpaper to remove any ridges on the area to be patched, such as a manufacturing join.
Clean the area to be patched, this makes the glue/solution adhere better to the tube. Especially so if you have sanded the area. I would usually use methalyated spirits and a lint free cloth of some sort.
Once the patch is applied, apply some chalk dust to the area, this makes sure that the solution/glue does not bond to anything else.