What can women do to get comfortable in the saddle? I am fairly new to cycling and have a road bike which I am really enjoying but I cannot get comfortable in the saddle. Not so much bum bones, but lady bits! Any suggestions?
Saddles can be very specific to the individual...but some general advice:


Try to find a local bike shop that will let you test ride different
saddles. Five minutes on a trainer is not enough, a good bike shop
will let you take a saddle on a real ride.
Talk with others that have similar biking style. A great mountain
bike saddle does not always make a great road saddle. A bit of an angle change or moving the saddle a bit forward or backward can have a big effect.
Try some saddles that are "lady specific" and those that others say
work well for the lady bits. I've heard good things about the Selle
Italia Lady Diva and the saddles from Adamo (the Adamo's are not 'lady specific' but the cutout seems to have similar effect).


Also, you may want to invest in some decent bike shorts and a good anti-chafe creme (I like 'Blue Steel Sports').

Some of the "issues with the tissues" will fade as you spend more time on the bike, but some won't unless you get a saddle that works for you. Don't settle...try different saddles until you find something that works for you.