How can I avoid thigh chafing despite already wearing cycling shorts? About one year ago, when I first started cycling, I noticed that during long trips (60km or more) I get skin burns on the inside of my quads. That is when I decided to buy myself a nice pair of cycling shorts with nice padding.

I read in several forums that in order to minimize the friction, one needs a very tight fit of the shorts and also underwear was a no-no.

However this remedy has stopped working for me. Now I am going to try to put some Kinesio tape on the skin, when the most friction is applied.

Is not wearing an underwear a bad idea? What can I do to prevent skin burn in that delicate area?

Clarification:
I have always been using my stock GIANT saddle, that I would categorize as a medium size.
Since it's on the inside of your thighs, it's a good bet that our seat is too wide, or not properly adjusted. 

A chamois crème will help, but I think the saddle change is a better idea.