Rear wheel rubs frame/cage while pedaling standing up I've heard (and noticed) the rear wheel rub on the frame and front derailleur cage when pedaling standing up. The frame shows some paint wear at one spot. And, in the lowest gear, if I crank hard, I can hear the tire rub on the derailleur cage.

I'm riding a Kona Splice (20", 29er).

In the lowest gear, the front derailleur cage is pretty close to the tire as it is.

Should I upgrade parts? Tighten parts? Or not stand up at all knowing this?

Edit #1

Tires: Bontrager 29x2.1"

Edit #2

2013 specs show Geax Evolutions, 29x1.9"

Edit #3

Went lapping our backyard circuit just now. It would rub when climbing the east and west staights.

Pic of the rubbing on the frame (not as bad as I remembered):


Pic of me essentially pushing with my thumb, the tire fairly close to the frame:


However, if I try to move the rim, it doesn't move really. It would seem that it's only the tire/rubber? Under inflated perhaps? I'm around or below 30psi.

Edit #4

I actually have a 2012 model, confirmed with the color of the frame and the posted pics.

The specs show 29x2.1, and Vittoria Mezcal, why did the shop I bought the bike from swap those out for some Geax?

Also, why did the following models come with 29x1.9"? Also, in 2014, the Splice became a cross bike :/
Any bike is going to flex when you pedal
The harder you pedal the more it will flex   

So first the question is if it is flexing too much
Inspect both the wheel and frame for any damage or weakness   

If the wheel is not centered then it will rub on one side first
Make sure it is centered   

If it is centered and no excessive flex then the tire is too large
If you cannot get the tip of your pinky finger between the tire and frame then you most likely don't have enough clearance
2.1 is extra-ordinary if the bike want not built for it - that is cross
I have a pure mountain bike that tops out at 2.1