I want to replace 52/36 chainrings with 50/34 chainrings on a Praxis Works I want to replace 52/36  chainrings with 50/34 chainrings on a Praxis Works. Is this possible without changing the crank? Also if possible would other modification be required such as the chain and possible the  front derailleur
Looking at the road Praxis chainrings page, 52/36 through 48/32 ring sets are all offered in 110mm BCD. All the roads cranks seem to have an evenly spaced 5 bolt pattern.

Without knowing exactly what crank you have I can't say for sure, but it seems likely you can fit smaller rings.