Do aircraft engineers take into consideration engine placement to avoid ground strikes in a cross-wind landing? On a multi-engine airplane with wing-mounted engines, do aircraft designers have a standard way of ensuring that the banked landings associated with cross-wind's do not cause a prop or engine-housing strike on the ground if the pilot were to over-bank?

Is there some rule such as, "the wing tip would need to be the first part to strike if the wheel is in contact with the ground", or similar standard of practice in design?
For jet aircraft, there is no rule about preventing a nacelle from contacting the ground before the wingtip. There will be a design requirement that the airplane can touch down at a certain angle of bank and have the landing gear touch down but not strike a nacelle or wing, but not whether nacelle or wing must strike first. The nacelle is already designed for a wheels-up landing, so it's possible it could survive better than a wing tip. While it's certainly more of a risk on 4-engine aircraft, it can also happen on twin jets.

Propeller aircraft are typically designed such that gear and wingtip will make contact without the propeller making contact, either through having gear directly below props on a low-wing configuration, or through a high-wing configuration. While a jet engine nacelle can sustain some structural damage in a strike, it will typically not affect the engine's operation. If a propeller gets damaged it could cause that engine to become unusable, making it much more difficult for the crew to successfully perform a go-around.