What throttle setting does an airliner use while cruising? As a passenger, I have always felt like the engine are not kept at take-off thrust/full throttle a few (tens of) seconds after take-off, and so for obvious reasons as fuel efficiency, engine wear prevention, noise control for population in airport area, and so on.

I have also read on this site or on excellent Twitter account of the A380 captain Dave Wallsworth lots of explanation about how to reduce the take-off thrust (eg. flex temp).

But I cannot find any information about the throttle level (N1 percentage may be more accurate) during cruise. My guess is it is not constant because of weight decreasing during flight due to fuel comsumption, but this is only a guess.

I know Airbus airliners have a "CLIMB" position on throttle which allow the autopilot to set N1 automatically to reach cruise speed, but I would like to know how N1 value evolves during cruise.

A320 throttle quadrant with lever at CLIMB position, with auto-throttle range:
(Above is the max cruise limit in standard ISA for the A320.)

It's 80.4% - 86.5% for the different weights and altitudes. Do note that 81% does not mean 81% of the available thrust. The maximum continuous thrust (MCT) at standard temperature is between 86% and 89% for the different cruise flight levels.

The colder the air, the lower the values, and vice versa for hot temperatures. If too hot above ISA, max flight level is limited for the higher weights due to MCT being the limiting factor.

For the A320 example, the thrust levers remain in the CLimb detent from thrust reduction to just before landing in normal operations.

For the 777-200, the range varies from 69% - 96.8% depending on the flight level and weight (with 86.8% - 94.7% being the optimum range). The wider range is due to the 777's wider payload/fuel range when compared to the smaller A320.