Should I do the collectibles while playing the story? This is how I'm currently playing the game:

I finish a certain region story arc(Ledecestrescire for example) and doing all the collectibles right after finishing the story arc. 

I am currently 64 hours in, currently in Sciropscire, and I feel like I should finish the story before doing all the collectibles. 

Should I continue this way? Would it be better to save the collectibles for later? 

I feel like I'll lose the interest in story but I love collecting wealth, as well as doing all those mysteries.