sir, my patient is periampullary adenocarcinoma with locally advanced stage, given gencitabin 1000 mg and oxaplatin 100 mg  4 days back, now total bilirubin is 2.2 in comparison to 1.5 before application of chemo, alkaline phosphate comes down to 612 from 685, other LFT parameters elevated moderately, kindly comment on state of health of my patient,