I have a microphone (Rode NT1) and guitar plugged into a Focusrite Sapphire Pro 24 running on OSX 10.10.2

I can monitor these inputs but want to route them to another application (Skype). Is it possible to route the signal to another application? I've tried copying to another Mix and also the Loopback setting.

At the OS level, the Sapphire is selected at both the input and output and also in Skype preferences.

For clarity, this question is not specifically about Skype but about how to route the Saffire mixer's input to another application on my system. I've looked at the Saffire Manual but can't see how to do this.

![enter image description here](https://i.stack.imgur.com/7SOLk.png)

In this particular application, you can only select 'Saffire' as the input, not individual channels.

![enter image description here](https://i.stack.imgur.com/jVLcG.png)