What if advertisers used IPs instead of URLs? Blokada works great. 100,000 trackers within one week is astonishing.

But I wonder how long it takes until advertisers and tracking companies begin to actively work against such filters. 
Wouldn't it be possible for them to just use plain IP-adresses instead of readable address-strings? Wouldn't that render Blokada, Pie-hole and others just useless?

Maybe I'm completely wrong about that, but what countermeasures could then be taken?