Serine/threonine-protein kinase, which may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation. Able to autophosphorylate. Interacts with MAP3K1. Interacts with FBXW8.
GO terms: MAP4K1 is active in the following subcellular-locations: cytoplasm, intracellular, membrane.