In a controlled trial, 5-HTP (300 mg per day) was shown to be effective in reducing many symptoms of fibromyalgia, including pain, morning stiffness, sleep disturbances, and anxiety.
For depression, 300 mg per day is often effective, though much of the research used 5-HTP in combination with drugs or was uncontrolled. For insomnia, a single 100-mg nighttime dose of 5-HTP was sufficient to improve the duration and depth of sleep in one placebo-controlled trial. For migraine headaches, amounts ranging from 400–600 mg per day have been shown to be effective at reducing the frequency and severity of attacks in most clinical trials. For tension headaches, 100 mg of 5-HTP taken three times per day led to a significant decrease in consumption of pain-relievers, but no significant change in headache duration or intensity.
Appetite reduction and weight loss (averaging 11 pounds in 12 weeks) has occurred with amounts of 600–900 mg daily. In another clinical trial, 750 mg per day has been shown to be effective at decreasing carbohydrate and fat intake, and promoting weight loss.
Disruptions in emotional well-being, including depression and anxiety, have been linked to serotonin imbalances in the brain. People with fibromyalgia often have low serotonin levels in their blood. Supplements of 5-HTP may increase serotonin synthesis in these cases. The cause of migraine headaches is related to abnormal serotonin function in blood vessels, and 5-HTP may help correct this abnormality. therefore, 5-HTP may provide a remedy for this condition.
Here is what people are saying about the benefits of 5 Htp.
"Tenho tomado 1 cápsula antes de deitar. Ainda não sinto mudança no humor - mas a qualidade do sono mudou. Durmo bem melhor agora. Recomendo...."
"I have been taking together with CoQ10 and I can tell you it works really great for my fibromyaligia symptoms. I no longer use the antidepressant doctors gave me a year ago. This provides me a good mood and it comes with vitamin B6 and vitamin C that reinforced its action...."
"I have been on this for about 4 days and so far has been really good. I am pretty satisfied with this product I have taken 200mg now down to 100mg and planning to take breaks as recommended by everyone. It has definitely been subtle for me but it has improved my mood, sleep and made me more calm and relaxed overall. Recommend for anyone that has so..."
" Great value. Good for anxiety. Also a beneficial sleep aid and no hangover effect. Careful if you are taking SSRI's due to the amount of serotonin levels. Taking 100mg (available on this site) during the day helps with social anxiety...."