Metribolone is a highly potent, orally active, non-aromatic, synthetic and metabolic androgen-like steroid (AAS) 19-Nostoxone and 17α-alkylated group that has never been clinically marketed but has been used for scientific research , As a combination of the androgen affinity test (AR) and AR ligand binding assay. It is a 17α-methylated derivative of nilotronone (trienol), which is similar to AAS, but is similar to other 17α-alkylated AASs with high hepatotoxic potential. Metribolone binds not only to AR but also to progesterone receptor (PR) and binds to glucocorticoid receptor (GR), and it is said to be the most effective AAS.
Although their structures are very similar, the effect of Metribolone and natriol is very different. Compared with methyl testosterone, it has an antibiotic ratio of 12000/6000 to the androgen ratio, making it the most effective steroid present. Methyltrienol may also be the strongest androgen receptor conjugate in all steroids. Methyltrienol requires a very small dose to see the size and intensity of growth. Methyltrienol can not be converted to estrogen, but it has progestin activity that promotes estrogenic action. This can be thought of as a “dry” compound if the subcutaneous (subcutaneous) water retention performance is not too great.
Methyltrienolone has an extremely strong binding affinity for the androgen receptor as well, even surpassing that of testosterone. This of course supports the assertion that Trenbolone is extremely anabolic as by binding to the androgen receptor a compound is able to activate the anabolic mechanisms that are dependent upon the androgen receptor, one of the many ways that anabolic steroids aid muscle growth. Androgen receptors also exist in adipose tissue. When stimulated by way of a compound such as Trienol binding to them, this can result in a higher then normal lipolytic action. So not only does this drug help to build muscle, it can help to burn fat.
Methyltrienolone is a modified form of Nandrolone. It differs by: 1) the addition of a methyl group at carbon 17alpha to protect the hormone during oral administration and 2) the introduction of double bonds at carbons 9 and 11, which increases its binding affinity and slows its metabolism. The resulting steroid is significantly more potent than its Nandrolone base, and displays a much longer half-life and lower affinity for serum-binding proteins in comparison. Methyltrienolone chemically differs from Trenbolone only by the addition of a methyl group at c-17. This alteration changes the activity of methyltrienolone considerably, however, such that this agent should not simply be considered an oral form of Trenbolone.
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