Introduction
Alzheimer disease (AD) is a neurodegenerative disease characterised by progressive dementia associated with global cognitive dysfunction. Methods
We conducted a systematic review and meta-analysis of clinical trials evaluating omega-3 supplementation in patients with AD. Objective
To determine if there is scientific evidence of the effectiveness of omega-3 supplementation in improving cognitive function in patients with AD.
Effectiveness of omega-3 fatty acid supplementation in patients with Alzheimer disease: A systematic review and meta-analysis
 
  Keywords
 
 
  
   Alzheimer disease
  
 
 
  
   Omega-3 fatty acids
  
 
 
  
   Cognitive function
  
 
 
  
   Randomised controlled trial
  
 
 
  
   Systematic review
  
 
Introduction
Alzheimer disease (AD) is a neurodegenerative disease characterised by <dis>progressive dementia</dis> associated with <dis>global cognitive dysfunction</dis>.
Methods
We conducted a systematic review and meta-analysis of clinical trials evaluating omega-3 supplementation in patients with AD.
Objective
To determine if there is scientific evidence of the effectiveness of omega-3 supplementation in improving cognitive function in patients with AD.
Search strategy
We included only randomised controlled trials (RCTs) from the following databases: Medline, Cochrane Central, Cinahl, and LILACS. 
An electronic search was also conducted using Google Scholar.
Study selection
Six articles met the eligibility criteria. 
The risk of bias was assessed following the Cochrane method.
Conclusion
There is no consistent evidence to support the effectiveness of omega-3 supplementation in improving cognitive function in AD patients in the short and medium term.
Introduction
Alzheimer disease (AD) is a neurodegenerative disease characterised by progressive dementia associated with global cognitive dysfunction.
Methods
We conducted a systematic review and meta-analysis of clinical trials evaluating omega-3 supplementation in patients with AD.
Objective
To determine if there is scientific evidence of the effectiveness of omega-3 supplementation in improving cognitive function in patients with AD.
Search strategy
We included only randomised controlled trials (RCTs) from the following databases: Medline, Cochrane Central, Cinahl, and LILACS. 
An electronic search was also conducted using Google Scholar.
Study selection
Six articles met the eligibility criteria. 
The risk of bias was assessed following the Cochrane method.
Conclusion
There is no consistent evidence to support the effectiveness of omega-3 supplementation in improving cognitive function in AD patients in the short and medium term.
Introduction
Alzheimer disease (AD) is a neurodegenerative disease characterised by <dis>progressive dementia</dis> associated with <dis>global cognitive dysfunction</dis>. Methods
We conducted a systematic review and meta-analysis of clinical trials evaluating omega-3 supplementation in patients with AD. Objective
To determine if there is scientific evidence of the effectiveness of omega-3 supplementation in improving cognitive function in patients with AD.
progressive dementia
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global cognitive dysfunction
DISABILITY