Development
We retrieved 22 studies, most of which were retrospective, and analysed various methodological variables including study population, diagnosis of periodontitis, definition of dementia, adjusted variables, and results. The different aetiopathogenic mechanisms that may affect the progression and interaction of these 2 conditions were also analysed.
Association between periodontal disease and dementia: A literature review
 
  Keywords
 
 
  
   Periodontitis
  
 
 
  
   Alzheimer's disease
  
 
 
  
   Dementia
  
 
 
  
   Inflammation
  
 
 
  
   Risk factors
  
 
 
  
   Review
  
 
Introduction
Periodontal disease and <dis>dementia</dis> are very prevalent, especially in elderly populations. 
Multiple studies have shown a link between these diseases; however, the conditions are highly heterogeneous and so is the diagnostic methodology, which may hinder interpretation and comparison of the results. 
The aim of this article is to provide a critical review of the literature linking these 2 processes.
Development
We retrieved 22 studies, most of which were retrospective, and analysed various methodological variables including study population, diagnosis of periodontitis, definition of <dis>dementia</dis>, adjusted variables, and results. 
The different aetiopathogenic mechanisms that may affect the progression and interaction of these 2 conditions were also analysed.
Conclusions
Although available evidence indicates a positive association between periodontitis and <dis>dementia</dis>, both the strength of that association and the presence of a causal relationship have yet to be determined.
Introduction
Periodontal disease and dementia are very prevalent, especially in elderly populations. 
Multiple studies have shown a link between these diseases; however, the conditions are highly heterogeneous and so is the diagnostic methodology, which may hinder interpretation and comparison of the results. 
The aim of this article is to provide a critical review of the literature linking these 2 processes.
Development
We retrieved 22 studies, most of which were retrospective, and analysed various methodological variables including study population, diagnosis of periodontitis, definition of dementia, adjusted variables, and results. 
The different aetiopathogenic mechanisms that may affect the progression and interaction of these 2 conditions were also analysed.
Conclusions
Although available evidence indicates a positive association between periodontitis and dementia, both the strength of that association and the presence of a causal relationship have yet to be determined.
Development
We retrieved 22 studies, most of which were retrospective, and analysed various methodological variables including study population, diagnosis of periodontitis, definition of <dis>dementia</dis>, adjusted variables, and results. The different aetiopathogenic mechanisms that may affect the progression and interaction of these 2 conditions were also analysed.
dementia
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