question: What is subject to the Orphan Drug Act ?
answer: diseases involving fewer than 200,000 patients in the United States , or larger populations in certain circumstances
turker_answer: The Orphan Drug Act is about diseases involving fewer than 200,000 patients in the United States , or larger populations in certain circumstances .
rule-based: Subject to the Orphan Drug Act is diseases involving fewer than 200,000 patients in the United States , or larger populations in certain circumstances .