Epidermolysis bullosa simplex
Epidermolysis bullosa simplex (EBS) is a disorder resulting from mutations in the genes encoding keratin 5 or keratin 14.: 598 Blister formation of EBS occurs at the dermoepidermal junction. Sometimes EBS is called epidermolytic.

Cause
Absence of keratin-5,14 since birth.

Diagnosis
Classification
Epidermolysis bullosa simplex may be divided into multiple types:

Management
No cure for EB
Treat symptoms
Protect skin, stop blister formation, promote healing
Prevent complications
Necessary treatment: use oral and topical steroid for healing and prevent complication
Maintain cool environment, avoid overheating and decreases friction

See also
Epidermolysis bullosa
List of cutaneous conditions caused by mutations in keratins

References
Further reading

GeneReviews/NCBI/UW/NIH entry on Epidermolysis Bullosa Simplex


== External links ==