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2-9 The alternative pathway is an amplification loop for C3b formation that is accelerated by properdin in the presence of pathogens.
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2-10 Membrane and plasma proteins that regulate the formation and stability of C3 convertases determine the extent of complement activation.
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2-11 Complement developed early in the evolution of multicellular organisms.
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2-12 Surface-bound C3 convertase deposits large numbers of C3b activity.