Teng, M.K., Smolyar, A., Tse, A.G.D., Liu, J.H., Liu, J., Hussey, R.E., Nathenson, S.G., Chang, H.C., Reinherz, E.L., and Wang, J.H.: Identification of a common docking topology with substantial variation among different TCR–MHC–peptide complexes. Curr. Biol. 1998, 8:409–412.
4-18 The CD4 and CD8 cell-surface proteins of T cells directly contact MHC molecules and are required to make an effective response to antigen.
Chang, H.C., Tan, K., Ouyang, J., Parisini, E., Liu, J.H., Le, Y., Wang, X., Reinherz, E.L., and Wang, J.H.: Structural and mutational analyses of CD8αβheterodimer and comparison with the CD8αα homodimer. Immunity 2005, 6:661–671.
Cheroutre, H., and Lambolez, F.: Doubting the TCR coreceptor function of CD8αα. Immunity 2008, 28:149–159.
Gao, G.F., Tormo, J., Gerth, U.C., Wyer, J.R., McMichael, A.J., Stuart, D.I., Bell, J.I., Jones, E.Y., and Jakobsen, B.Y.: Crystal structure of the complex between human CD8ααand HLA-A2. Nature 1997, 387:630–634.
Gaspar, R., Jr., Bagossi, P., Bene, L., Matko, J., Szollosi, J., Tozser, J., Fesus, L., Waldmann, T.A., and Damjanovich, S.: Clustering of class I HLA oligomers with CD8 and TCR: three-dimensional models based on fluorescence resonance energy transfer and crystallographic data. J. Immunol. 2001, 166:5078–5086.
Kim, P.W., Sun, Z.Y., Blacklow, S.C., Wagner, G., and Eck, M.J.: A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8. Science 2003, 301:1725–1728.
Moody, A.M., North, S.J., Reinhold, B., Van Dyken, S.J., Rogers, M.E., Panico, M., Dell, A., Morris, H.R., Marth, J.D., and Reinherz, E.L.: Sialic acid capping of CD8βcore 1-O-glycans controls thymocyte-major histocompatibility complex class I interaction. J. Biol. Chem. 2003, 278:7240–7260.
Walker, L.J., Marrinan, E., Muenchhoff, M., Ferguson, J., Kloverpris, H., Cheroutre, H., Barnes, E., Goulder, P., and Klenerman, P.: CD8αα expression marks terminally differentiated human CD8+ T cells expanded in chronic viral infection. Front Immunol. 2013, 4:223.
Wang, J.H., and Reinherz, E.L.: Structural basis of T cell recognition of peptides bound to MHC molecules. Mol. Immunol. 2002, 38:1039–1049.
Wang, R., Natarajan, K., and Margulies, D.H.: Structural basis of the CD8αβ/ MHC class I interaction: focused recognition orients CD8βto a T cell proximal position. J. Immunol. 2009, 183:2554–2564.