Promyelocyte, bone marrow smear, human, Giemsa, ×2,200.
The promyelocyte exhibits a round nucleus with one or more nucleoli (N) present. The cytoplasm is basophilic and exhibits relatively large blue/black azurophilic granules (AG).
Eosinophilic myelocyte, bone marrow smear, human, Giemsa, ×2,200.
The eosinophilic myelocyte exhibits a nucleus the same as that described for the neutrophilic myelocyte. The cytoplasm, however, contains the large specific granules characteristic of eosinophils, but they are fewer in number.
Neutrophilic myelocyte, bone marrow smear, human, Giemsa, ×2,200.
The neutrophilic myelocyte retains the round nucleus, but nucleoli are now absent. The cytoplasm exhibits small pink-to-red specific granules.
Eosinophilic metamyelocyte, bone marrow smear, human, Giemsa, ×2,200.
The eosinophilic metamyelocyte exhibits a kidney or bean  sha ped nucleus. The cytoplasm exhibits numerous the characteristic eosinophilic granules that are present throughout the cytoplasm.
Neutrophilic metamyelocyte, bone marrow smear, human, Giemsa, ×2,200.
The neutrophilic metamyelocyte differs from its precursor by the presence of a kidney or bean shaped nucleus. The small, pink-to-red specific granules are now seen in the cytoplasm and few or no azurophilic granules are present.
Eosinophilic band cell, bone marrow smear, human, Neutrophilic band cell, bone marrow smear, human,
Giemsa, ×2,200. Giemsa, ×2,200.
The eosinophilic band cell exhibits a horseshoe-shaped nu-The band or non-segmented neutrophil exhibits a horseshoe cleus. Its cytoplasm is filled with the eosinophilic granules. shaped nucleus with abundant small, pink-to-red specific granules in the cytoplasm.
KEY AG, azurophilic granules G, Golgi apparatus N, nucleoli
OVERVIEW AND CLASSIFICATION OF MUSCLE / 310 SKELETAL MUSCLE / 311 Myofibrils and Myofilaments / 314 The Contraction Cycle / 317 Motor Innervation / 322 Sensory Innervation / 324 Development, Repair, Healing, and Renewal / 325 CARDIAC MUSCLE / 327 Structure of Cardiac Muscle / 328 Injury and Repair / 331 SMOOTH MUSCLE / 331 Structure of Smooth Muscle / 331 Functional Aspects of Smooth Muscle / 335 Renewal, Repair, and Differentiation / 336 Folder 11.1 Functional Considerations: Muscle Metabolism and Ischemia / 316 Folder 11.2 Clinical Correlation: Muscular Dystrophies—Dystrophin and Dystrophin-Associated Proteins / 319 Folder 11.3 Functional Considerations: The Sliding Filament Model / 323 Folder 11.4 Clinical Correlation: Myasthenia Gravis / 325 Folder 11.5 Functional Considerations: Comparison of the Three Muscle Types / 337
Muscle tissue is responsible for movement of the body and its parts and for changes in the size and shape of internal organs. This tissue is characterized by aggregates of specialized, elongated cells arranged in parallel array that have the primary role of contraction (Fig. 11.1).
Myofilament interaction is responsible for muscle cell contraction.