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MATERNAL AND FETAL.IMMUNOLOGY .......i.... 1209
VIRAL INFECTIONS ...i.....i............i...... 1210
BACTERIAL INFECTIONS .............i.......... 1220
PROTOZOAL INFECTIONS .i.i....i.............. 1225
BIOTERRORISM . . . . . . . . . . . . . . . . . . . . . . . . . . . .... 1228
According to many authorities, inluena exerts a very pernicious influence upon pregnancy. t would appear that the fects of inluena must vary with the severiy of the epidemic, and more particuary with the frequeny of pneumonic com plications. As a rule, any septic condition oers a worse prognosis in prenany. Several instances have been reported of transmission of the oending bacteria to the oetus.
-J. Whitridge Williams (1903)
Infections have historically been a major cause of maternal and fetal morbidity and mortality worldwide, and they remain so in the 21st century. he unique maternal-fetal vascular connection in some cases serves to protect the fetus from infectious agents, whereas in other instances it provides a conduit for their transmission to the fetus. Maternal serological status, gestational age at the time infection is acquired, the mode of acquisition, and the immunological status of both the mother and her fetus all inluence disease outcome.