Hildner, K., Edelson, B.T., Purtha, W.E., Diamond, M., Matsushita, H., Kohyama, M., Calderon, B., Schraml, B.U., Unanue, E.R., Diamond, M.S., et al.: Batf3 deficiency reveals a critical role for CD8α+ dendritic cells in cytotoxic T cell immunity. Science 2008, 322:1097–1100.
Segura, E., and Villadangos, J.A.: A modular and combinatorial view of the antigen cross-presentation pathway in dendritic cells. Traffic 2011, 12:1677–1685.
6-6 Peptide:MHC class II complexes are generated in acidified endocytic vesicles from proteins o.btained through endocytosis, phagocytosis, and autophagy.
Dengjel, J., Schoor, O., Fischer, R., Reich, M., Kraus, M., Müller, M., Kreymborg, K., Altenberend, F., Brandenburg, J., Kalbacher, H., et al.: Autophagy promotes MHC class II presentation of peptides from intracellular source proteins. Proc. Natl Acad. Sci. USA 2005, 102:7922–7927.
Deretic, V., Saitoh, T., and Akira, S.: Autophagy in infection, inflammation and immunity. Nat. Rev. Immunol. 2013, 13:722–737.
Godkin, A.J., Smith, K.J., Willis, A., Tejada-Simon, M.V., Zhang, J., Elliott, T., and Hill, A.V.: Naturally processed HLA class II peptides reveal highly conserved immunogenic flanking region sequence preferences that reflect antigen processing rather than peptide–MHC interactions. J. Immunol. 2001, 166:6720–6727.
Hiltbold, E.M., and Roche, P.A.: Trafficking of MHC class II molecules in the late secretory pathway. Curr. Opin. Immunol. 2002, 14:30–35.
Hsieh, C.S., deRoos, P., Honey, K., Beers, C., and Rudensky, A.Y.: A role for cathepsin L and cathepsin S in peptide generation for MHC class II presentation. J. Immunol. 2002, 168:2618–2625.
Lennon-Duménil, A.M., Bakker, A.H., Wolf-Bryant, P., Ploegh, H.L., and Lagaudrière-Gesbert, C.: A closer look at proteolysis and MHC-class-II– restricted antigen presentation. Curr. Opin. Immunol. 2002, 14:15–21.
Li, P., Gregg, J.L., Wang, N., Zhou, D., O’Donnell, P., Blum, J.S., and Crotzer, V.L.: Compartmentalization of class II antigen presentation: contribution of cytoplasmic and endosomal processing. Immunol. Rev. 2005, 207:206–217.
Maric, M., Arunachalam, B., Phan, U.T., Dong, C., Garrett, W.S., Cannon, K.S., Alfonso, C., Karlsson, L., Flavell, R.A., and Cresswell, P.: Defective antigen processing in GILT-free mice. Science 2001, 294:1361–1365.
Münz, C.: Enhancing immunity through autophagy. Annu. Rev. Immunol. 2009, 27:423–449.