Weitzmann MN, Pacifici R: Estrogen deficiency and bone loss: an inflammatory tale, J Clin Invest 116:1186–1194, 2006. [Excellent review of current understanding of the relationship between estrogen and osteoporosis.]
Silva BC, Bilezikian JP: Parathyroid hormone: anabolic and catabolic actions on the skeleton, Curr Opin Pharmacol 22:41–50, 2015. [Nice summary of effects of parathyroid hormone on calcium and bone metabolism.]
Roodman GD, Windle JJ: Paget disease of bone, J Clin Invest 115:200– 208, 2005. [Concise, nicely illustrated, summary of clinicopathologic manifestation of Paget disease.]
Singer FR: The etiology of Paget’s Disease of bone: viral and genetic interactions, Cell Metab 13:5–6, 2011. [Very good review about the viral and genetic pathways in Paget disease.]
Seamon J, Keller T, et al: The pathogenesis of nontraumatic osteonecrosis, Arthritis 601763, 2012. [Summarizes recent developments regarding pathophysiology of femoral head osteonecrosis.]
Klein MJ, Siegal GP: Osteosarcoma: anatomic and histologic variants, Am J Clin Pathol 125:555–581, 2006. [Most recent update on classification of osteosarcoma.]
Wagner ER, Luther G, Zhu G, et al: Defective osteogenic differentiation in the development of osteosarcoma, Sarcoma 2011:325238, http://ebooksmedicine.net 2011. [Discusses molecular relationship between normal osteoblast development the pathogenesis of osteosarcoma.]
Bovee JV, Hogendoorn PC, Wunder JS, et al: Cartilage tumours and bone development: molecular pathology and possible therapeutic targets, Nat Rev Cancer 10:481–488, 2010. [A good review of the known genetic abnormalities in these tumors]
Pansuriya TC, van Eijk R, d’Adamo P, et al: Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome, Nat Genet 43:1256–1261, 2011. [Seminal article identifying IDH mutations in inherited cartilage tumors.]
Wuyts W, Van Hul W: Molecular basis of multiple exostoses: mutations in the EXT1 and EXT2 genes, Hum Mutat 15:220–227, 2000. [Discussion of genetic basis of multiple osteochondroma syndrome.]
Erkizan HV, Uversky VN, Toretsky JA: Oncogenic partnerships: EWSFLI1 protein interactions initiate key pathways of Ewing’s sarcoma, Clin Cancer Res 16:4077–4083, 2010. [Excellent summary of molecular effects of the EWS-FLI1 fusion protein found in Ewing sarcoma.]
Giant Cell Tumor of Bone
Robinson D, Einhorn TA: Giant cell tumor of bone: a unique paradigm of stromal-hematopoietic cellular interactions, J Cell Biochem 55:300– 303, 1994. [Nice discussion of molecular mechanisms underlying giant cell tumor and insight gained regarding normal bone remodeling.]