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Figure 26-1. Diagram of the hypothalamic–pituitary axis. Indicated on the left is the hypothalamic–neurohypophyseal system, consisting of supraoptic and paraventricular neurons, axons of which terminate on blood vessels in the posterior pituitary (neurohypophysis). The hypothalamic–adenohypophyseal system is illustrated on the right. Tuberoinfundibular neurons, the source of the hypothalamic regulatory hormones, terminate on the capillary plexus in the median eminence. (Courtesy of Dr. J.B. Martin.)
Chapter  26    The Hypothalamus and Neuroendocrine Disorders
Development of the Nervous System
In this chapter and the next one on aging, we consider the effects of growth, maturation, and aging on the nervous system. These are discussed in some detail because certain aspects of neurologic diseases are meaningful only when viewed against the background of these natural age-linked changes. Developmental diseases of the nervous system, for example, malformations, genetic defects, and other forms of damage that are acquired in the intrauterine period of life, are considered in Chap. 37.