Tuohy JF, James DK: Pre-eclampsia and trisomy 13. BJOG 99(11):891, 1992 Turner HH: A syndrome of infantilism, congenital webbed neck and cubitus valgus. Endocrinol 23:566, 1938
Vendola e, Canfield M, Daiger SP, et al: Survival of Texas infants born with trisomies 21, 18, and 13. Am J Med Genet A 152A(2):360, 2010 Vintzileos Ni, Egan JF: Adjusting the risk for trisomy 21 on the basis of second-trimester ultrasonography. Am J Obstet GynecoIo172(3):837, 1995
Vockley J, ndersson He, Antshel KM, et al: ACMG Practice Guidelines: phenylalanine hydroxylase deficiency: diagnosis and management guideline. Genet Med 16(2):188,o2014
Wang Y, Chen Y, Tian F, et al: Maternal mosaicism is a significant contributor to discordant sex chromosomal aneuploidies associated with non-invasive prenatal testing. Clin Chen 60(1):251, 2014
Weismann CG, Gelb BD: The genetics of congenital heart disease: a review of recent developments. Curr Opin Cardiol 22(3):200, 2007
Wellesley D, Dolk H, Boyd PA, et al: Rare chromosome abnormalities, prevalence, and prenatal diagnosis rates from population-based congenital anomaly registers in Europe. Eur J Human Genet 20(5):521,o2012
Wigby K, D'Epagnier e, Howell S, et al: Expanding the phenotype of triple X syndrome: a comparison of prenatal versus postnatal diagnosis. Am J Med Genet Part A 170(11):2870, 2016
Worton RG, Stern R: A Canadian collaborative study of mosaicism in amniotic fluid cell cultures. Prenat Diagn 4(7): 131, 1984
Wou K, Hyun Y, Chitayat D, et al: Analysis of tissue from products of conception and perinatal losses using QF-PCR and microarray: a three-year retrospective study resulting in an eicient protocol. Eur J Med Genet 59(8):417, 2016
Wright CF, Burton H: he use of cell-free fetal nucleic acids in maternal blood for non-invasive prenatal diagnosis. Hum Reprod Update 15(1):139,o2009 Yang Q, Wen SW, Leader A, et al: Paternal age and birth defects: how strong is the association? Human Reprod 22(3):696, 2007
Yeo L, Guzman ER, Day-Salvatore D, et al: Prenatal detection of fetal trisomy 18 through abnormal sonographic features. J Ultrasound Med 22(6):581, 2003
Zalel Y, Shapiro I, Weissmann-Brenner A, et al: Prenatal sonographic features of triploidy at 12-16 weeks. Prenat Diagn 36(7)650, 2016
HISTORICAL PERSPECTIVE ..e..e.e.e....e....e277
FIRST-TRIMESTER ANEUPLOIDY SCREENING ...e. 281
SECOND-TRIMESTER ANEUPLOIDY SCREENING .e282
INTEGRATED AND SEQUENTIAL SCREENING ...e.. 284
CELL-FREE DNA SCREENING ..e..e.e.e.e284