Suzuki, K., Kawamoto, S., Maruya, M., and Fagarasan, S.: GALT: organization and dynamics leading to IgA synthesis. Adv. Immunol. 2010, 107:153–185.
12-3 The intestine has distinctive routes and mechanisms of antigen uptake.
Anosova, N.G., Chabot, S., Shreedhar, V., Borawski, J.A., Dickinson, B.L., and Neutra, M.R.: Cholera toxin, E. coli heat-labile toxin, and non-toxic derivatives induce dendritic cell migration into the follicle-associated epithelium of Peyer’s patches. Mucosal Immunol. 2008, 1:59–67.
Hase, K., Kawano, K., Nochi, T., Pontes, G.S., Fukuda, S., Ebisawa, M., Kadokura, K., Tobe, T., Fujimura, Y., Kawano, S., et al.: Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response. Nature 2009, 462:226–230.
Jang, M.H., Kweon, M.N., Iwatani, K., Yamamoto, M., Terahara, K., Sasakawa, C., Suzuki, T., Nochi, T., Yokota, Y., Rennert, P.D., et al.: Intestinal villous M cells: an antigen entry site in the mucosal epithelium. Proc. Natl Acad. Sci. USA 2004, 101:6110–6115.
Lelouard, H., Fallet, M., de Bovis, B., Meresse, S., and Gorvel, J.P.: Peyer's patch dendritic cells sample antigens by extending dendrites through M cell-specific transcellular pores. Gastroenterology 2012, 142:592–601.
Mabbott, N.A., Donaldson, D.S., Ohno, H., Williams, I.R., and Mahajan, A. Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium. Mucosal Immunol. 2013, 6:666–677.
Sato, S., Kaneto, S., Shibata, N., Takahashi, Y., Okura, H., Yuki, Y., Kunisawa, J., and Kiyono, H.: Transcription factor Spi-B-dependent and -independent pathways for the development of Peyer’s patch M cells. Mucosal Immunol. 2013, 6:838–846.
Salazar-Gonzalez, R.M., Niess, J.H., Zammit, D.J., Ravindran, R., Srinivasan, A., Maxwell, J.R., Stoklasek, T., Yadav, R., Williams, I.R., Gu, X., et al.: CCR6-mediated dendritic cell activation of pathogen-specific T cells in Peyer’s patches. Immunity 2006, 24:623–632.
Zhao, X., Sato, A., Dela Cruz, C.S., Linehan, M., Luegering, A., Kucharzik, T., Shirakawa, A.K., Marquez, G., Farber, J.M., Williams, I., et al.: CCL9 is secreted by the follicle-associated epithelium and recruits dome region Peyer’s patch CD11b+ dendritic cells. J. Immunol. 2003, 171:2797–2803.
12-4 The mucosal immune system contains large numbers of effector lymphocytes even in the absence of disease.