CH genes in the course of an immune response. 415 10-12 Cytokines made by TFH cells direct the choice of responses. 418 10-13 B cells that survive the germinal center reaction memory cells. 419 10-14 Some antigens do not require T-cell help to induce  B-cell responses.
Summary. 421
The distributions and functions of immunoglobulin classes. 422 10-15 Antibodies of different classes operate in distinct places and have distinct effector functions.
10-16 Polymeric immunoglobulin receptor binds to the  Fc regions of IgA and IgM and transports them  across epithelial barriers.
10-17 The neonatal Fc receptor carries IgG across the  placenta and prevents IgG excretion from the body. 426 12-6 Priming of lymphocytes in one mucosal tissue may 13-4 SCID can also be due to defects in the purine induce protective immunity at other mucosal  salvage pathway. 538 surfaces. 502 12-7 Distinct populations of dendritic cells control can result in SCID. 538 mucosal immune responses. 503 can cause severe immunodeficiency. 539 roles in mucosal immune responses. 505 12-9 Antigen-presenting cells in the intestinal mucosa development result in severe immunodeficiencies. 539 acquire antigen by a variety of routes. 505 12-10 Secretory IgA is the class of antibody associated in antibody production that cause an inability to  with the mucosal immune system. 506 clear extracellular bacteria and some viruses. 541 12-11 T-independent processes can contribute to IgA 13-9 Immune deficiencies can be caused by defects in production in some species. 509
B-cell or T-cell activation and function that lead to  abnormal antibody responses. 543 12-12 IgA deficiency is relatively common in humans but  may be compensated for by secretory IgM. 509 13-10 Normal pathways for host defense against different infectious agents are pinpointed by genetic deficiencies 12-13 The intestinal lamina propria contains antigen of cytokine pathways central to type 1/TH1 and typeexperienced T cells and populations of unusual 3/TH17 responses. 546 innate lymphoid cells. 510 13-11 Inherited defects in the cytolytic pathway of 12-14 The intestinal epithelium is a unique compartment of the immune system. 511 proliferation and inflammatory responses to viral
Summary. 514 infections. 548