diff --git "a/H00042.json" "b/H00042.json" new file mode 100644--- /dev/null +++ "b/H00042.json" @@ -0,0 +1,7260 @@ +{ + "id": "H00042", + "disease": { + "id": "H00042", + "names": [ + "Glioma", + "SUPERGRP Solid tumor [DS:H02421]" + ], + "dbLinks": { + "icd10": [ + "C71" + ], + "mesh": [ + "D005910" + ] + }, + "category": "Cancer" + }, + "riskFactors": [ + { + "text": "smoking, alcohol consumption", + "score": 14.396824836730957, + "articlesIDs": [ + "29972422", + "31450905" + ] + }, + { + "text": "smoking, alcohol consumption, systemic arterial hypertension (sah)", + "score": 14.281025886535645, + "articlesIDs": [ + "31450905" + ] + }, + { + "text": "diabetes mellitus (dm)", + "score": 14.243194580078125, + "articlesIDs": [ + "26683358", + "30249881", + "31450905", + "30545764" + ] + }, + { + "text": "newborn cns abnormalities", + "score": 14.188250541687012, + "articlesIDs": [ + "23562044" + ] + }, + { + "text": "systemic arterial hypertension (sah) and diabetes mellitus (dm)", + 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"score": 10.824043273925781, + "articlesIDs": [ + "35326529" + ] + }, + { + "text": "to carbamate herbicides", + "score": 10.814327239990234, + "articlesIDs": [ + "31344646" + ] + }, + { + "text": "t-a-g haplotype", + "score": 10.812324523925781, + "articlesIDs": [ + "25966079" + ] + }, + { + "text": "type ii and gestational diabetes in taiwan", + "score": 10.81184196472168, + "articlesIDs": [ + "36088507" + ] + }, + { + "text": "gbm", + "score": 10.809810638427734, + "articlesIDs": [ + "31281481" + ] + }, + { + "text": "extremely low-frequency electromagnetic fields", + "score": 10.808982849121094, + "articlesIDs": [ + "28401165" + ] + }, + { + "text": "tert rs10069690 polymorphism", + "score": 10.808284759521484, + "articlesIDs": [ + "31454181" + ] + }, + { + "text": "medical radiation, exogenous hormone use", + "score": 10.799196243286133, + "articlesIDs": [ + "28267708" + ] + }, + { + "text": "sox9 rs1042667", + "score": 10.798686981201172, + "articlesIDs": [ + "27589569" + ] + }, + { + "text": "c.910a\u003eg and c.1779c\u003eg genetic polymorphisms", + "score": 10.795204162597656, + "articlesIDs": [ + "23918303" + ] + }, + { + "text": "the variant 'c' allele", + "score": 10.788230895996094, + "articlesIDs": [ + "22706378" + ] + }, + { + "text": "waist-to-hip ratio (whr)", + "score": 10.788215637207031, + "articlesIDs": [ + "29655085" + ] + }, + { + "text": "the gm 3/17 genotype", + "score": 10.779802322387695, + "articlesIDs": [ + "25097800" + ] + }, + { + "text": "hay fever (or 0.72; ci 0.61-0.86), and eczema", + "score": 10.767141342163086, + "articlesIDs": [ + "35118581" + ] + }, + { + "text": "patients with lower baseline ft4 concentrations", + "score": 10.764751434326172, + "articlesIDs": [ + "31173083" + ] + }, + { + "text": "those in the highest decile of cumulative call time", + "score": 10.764650344848633, + "articlesIDs": [ + "28340909" + ] + }, + { + "text": "meningioma in mixed dairy and cow farming", + "score": 10.756030082702637, + "articlesIDs": [ + "35781883" + ] + }, + { + "text": "the p.thr241met polymorphism", + "score": 10.752338409423828, + "articlesIDs": [ + "36264998" + ] + }, + { + "text": "rs891835, rs6470745, and rs55705857", + "score": 10.74582576751709, + "articlesIDs": [ + "30778791" + ] + }, + { + "text": "individuals with the rs3212986-aa", + "score": 10.745810508728027, + "articlesIDs": [ + "26264164" + ] + }, + { + "text": "cumulative doses of alkylating agents", + "score": 10.744831085205078, + "articlesIDs": [ + "33033142" + ] + }, + { + "text": "elf in the recent past and glioma.\n\nimpact:\noccupational elf exposure", + "score": 10.740992546081543, + "articlesIDs": [ + "24935666" + ] + }, + { + "text": "body mass index (bmi), waist circumference (wc) and waist-to-hip ratio (whr)", + "score": 10.736383438110352, + "articlesIDs": [ + "29655085" + ] + }, + { + "text": "the fen1-69gg or 4150gg genotype", + "score": 10.734701156616211, + "articlesIDs": [ + "23184144" + ] + }, + { + "text": "gestational diabetes in denmark", + "score": 10.729774475097656, + "articlesIDs": [ + "36088507" + ] + }, + { + "text": "those of genotype ac (or=1.37; 95% ci=1.13-1.66) and cc", + "score": 10.728052139282227, + "articlesIDs": [ + "27589569" + ] + }, + { + "text": "combined oestrogen-progestagen, and 2.2 (0.9-5.5) for progestagen", + "score": 10.722731590270996, + "articlesIDs": [ + "24138870" + ] + }, + { + "text": "efemp1 rs3791679 polymorphism", + "score": 10.718305587768555, + "articlesIDs": [ + "27706619" + ] + }, + { + "text": "relative leukocyte telomere length (rltl)", + "score": 10.713746070861816, + "articlesIDs": [ + "30560391" + ] + }, + { + "text": "glioma in pig farming", + "score": 10.71170425415039, + "articlesIDs": [ + "35781883" + ] + }, + { + "text": "patients with known cerebrovascular disease", + "score": 10.708617210388184, + "articlesIDs": [ + "34468884" + ] + }, + { + "text": "cortical location, tumor recurrence, and age at diagnosis", + "score": 10.705060958862305, + "articlesIDs": [ + "31036424" + ] + }, + { + "text": "the breast cancer snp lsp1 rs3817198", + "score": 10.703634262084961, + "articlesIDs": [ + "24681604" + ] + }, + { + "text": "age ≥ 60 years (or = 3.32, p = 0.041), total tumor/edema volume ≤ 64cm(3)", + "score": 10.69667911529541, + "articlesIDs": [ + "26385488" + ] + }, + { + "text": "upfront radiotherapy", + "score": 10.693567276000977, + "articlesIDs": [ + "26970559" + ] + }, + { + "text": "pp65 protein (or = 3.1, 95% ci: 1.8-5), and gb nucleic acids", + "score": 10.69172191619873, + "articlesIDs": [ + "30888562" + ] + }, + { + "text": "overnutrition", + "score": 10.688465118408203, + "articlesIDs": [ + "37630792" + ] + }, + { + "text": "who had the most cumulative calls", + "score": 10.688455581665039, + "articlesIDs": [ + "30446214" + ] + }, + { + "text": "common genetic variants in efemp1 gene", + "score": 10.67880630493164, + "articlesIDs": [ + "25638659" + ] + }, + { + "text": "haplotype \"gg\"", + "score": 10.666332244873047, + "articlesIDs": [ + "25638659" + ] + }, + { + "text": "drd5 (p = 3.0 × 10-79), wdr1", + "score": 10.66122055053711, + "articlesIDs": [ + "28339748" + ] + }, + { + "text": "egf rs4444903 polymorphism", + "score": 10.660938262939453, + "articlesIDs": [ + "23645212" + ] + }, + { + "text": "medulloblastoma (3.11 (2.79, 3.47)), and ependymal-tumors", + "score": 10.660865783691406, + "articlesIDs": [ + "33946020" + ] + }, + { + "text": "nlr and igf-1", + "score": 10.656745910644531, + "articlesIDs": [ + "34564026" + ] + }, + { + "text": "those with diabetes of long-term duration", + "score": 10.650845527648926, + "articlesIDs": [ + "26093337" + ] + }, + { + "text": "the trp/trp genotype of xrcc1 arg194trp", + "score": 10.644363403320312, + "articlesIDs": [ + "27706616" + ] + }, + { + "text": "hla-i allele b*07:02", + "score": 10.633071899414062, + "articlesIDs": [ + "29572931" + ] + }, + { + "text": "the ins/ins genotype of nfkb -94ins/delattg", + "score": 10.627779006958008, + "articlesIDs": [ + "30450997" + ] + }, + { + "text": "agricultural exposure for more than 10 years", + "score": 10.626604080200195, + "articlesIDs": [ + "33876308" + ] + }, + { + "text": "patients reporting obese body weights 1-5 years prior to study interview", + "score": 10.623964309692383, + "articlesIDs": [ + "23666204" + ] + }, + { + "text": "≥10 years after first regular mobile phone use", + "score": 10.621297836303711, + "articlesIDs": [ + "21862434" + ] + }, + { + "text": "mutant idh1 or idh2", + "score": 10.614155769348145, + "articlesIDs": [ + "22922872" + ] + }, + { + "text": "parental lead exposure was 1.17 (95 % ci: 0.99, 1.34).\n\nconclusions:\nlead", + "score": 10.612009048461914, + "articlesIDs": [ + "32146339" + ] + }, + { + "text": "female patients", + "score": 10.59902572631836, + "articlesIDs": [ + "31108072" + ] + }, + { + "text": "the a mutant allele of icam-1 r241g", + "score": 10.594271659851074, + "articlesIDs": [ + "24289603" + ] + }, + { + "text": "rs78378222 snp", + "score": 10.585737228393555, + "articlesIDs": [ + "22706378" + ] + }, + { + "text": "vascular endothelial growth factor receptor 2 rs2305948 gene polymorphism", + "score": 10.583344459533691, + "articlesIDs": [ + "35029892" + ] + }, + { + "text": "rare inherited mutations in pot1 (protection of telomeres protein 1)", + "score": 10.57197093963623, + "articlesIDs": [ + "26014050" + ] + }, + { + "text": "rs1800067 g and rs2276466 g allele frequencies", + "score": 10.56695556640625, + "articlesIDs": [ + "23991957" + ] + }, + { + "text": "after menopause and with hrt use", + "score": 10.561601638793945, + "articlesIDs": [ + "21359526" + ] + }, + { + "text": ", ever statin use", + "score": 10.555450439453125, + "articlesIDs": [ + "31559554" + ] + }, + { + "text": "single-nucleotide polymorphisms (snps) in the hla-ii region", + "score": 10.55030345916748, + "articlesIDs": [ + "29572931" + ] + }, + { + "text": "dsw patients", + "score": 10.545825004577637, + "articlesIDs": [ + "34058360" + ] + }, + { + "text": "serum low-density lipoprotein cholesterol and plasma hba1c", + "score": 10.543464660644531, + "articlesIDs": [ + "33020596" + ] + }, + { + "text": "cdbi-based undernutrition (or = 1.08, 95% ci: 1.06-1.12) and overnutrition", + "score": 10.53761100769043, + "articlesIDs": [ + "37630792" + ] + }, + { + "text": "mutations of the seven loci", + "score": 10.536163330078125, + "articlesIDs": [ + "26243184" + ] + }, + { + "text": "igf-1 in the highest quartile", + "score": 10.532790184020996, + "articlesIDs": [ + "34564026" + ] + }, + { + "text": "age, who glioma classification", + "score": 10.524677276611328, + "articlesIDs": [ + "33878595" + ] + }, + { + "text": "with gstt1 null status in individuals of european ethnicity", + "score": 10.521956443786621, + "articlesIDs": [ + "25735248" + ] + }, + { + "text": "mutations in tumor suppressor gene p53 and its expression", + "score": 10.517451286315918, + "articlesIDs": [ + "21434862" + ] + }, + { + "text": "highest ses quintile", + "score": 10.508710861206055, + "articlesIDs": [ + "25421378" + ] + }, + { + "text": "treh, il4r", + "score": 10.506326675415039, + "articlesIDs": [ + "22369735" + ] + }, + { + "text": "age under 1, neurofibromatosis type i status", + "score": 10.50216293334961, + "articlesIDs": [ + "28259295" + ] + }, + { + "text": "the gg genotype of the ercc2 rs13181 polymorphism", + "score": 10.501222610473633, + "articlesIDs": [ + "27323065" + ] + }, + { + "text": "ercc1 rs3212986 is a common single nucleotide polymorphism", + "score": 10.500972747802734, + "articlesIDs": [ + "26264164" + ] + }, + { + "text": "mp use", + "score": 10.486566543579102, + "articlesIDs": [ + "30633716" + ] + }, + { + "text": "the ag and gg genotypes of the rs4977756 (cdkn2a/b)", + "score": 10.47866439819336, + "articlesIDs": [ + "31721021" + ] + }, + { + "text": "shorter (ca)(n) repeat variants", + "score": 10.474448204040527, + "articlesIDs": [ + "21960689" + ] + }, + { + "text": "with ever use of wireless phones", + "score": 10.472620010375977, + "articlesIDs": [ + "29709736" + ] + }, + { + "text": "physician-diagnosed asthma (or = 0.73; ci 0.58-0.92), hay fever", + "score": 10.470235824584961, + "articlesIDs": [ + "35118581" + ] + }, + { + "text": "anxa5 polymorphism", + "score": 10.458677291870117, + "articlesIDs": [ + "30536196" + ] + }, + { + "text": "occupational exposures to pesticides", + "score": 10.454595565795898, + "articlesIDs": [ + "33876308" + ] + }, + { + "text": "cxcl12-3' a/a genotypes", + "score": 10.453176498413086, + "articlesIDs": [ + "26782381" + ] + }, + { + "text": "mutations in the gene", + "score": 10.429481506347656, + "articlesIDs": [ + "31041803" + ] + }, + { + "text": "long-term heavy smoking", + "score": 10.427549362182617, + "articlesIDs": [ + "26409568" + ] + }, + { + "text": "the gm 3 allele", + "score": 10.42741870880127, + "articlesIDs": [ + "25097800" + ] + }, + { + "text": "mthfr c677t variant", + "score": 10.420398712158203, + "articlesIDs": [ + "23846816" + ] + }, + { + "text": "air pollution, and radiofrequency electromagnetic waves", + "score": 10.416935920715332, + "articlesIDs": [ + "31526552" + ] + }, + { + "text": "anti-hcmv antibodies (immunoglobulin g [igg] and immunoglobulin m [igm])", + "score": 10.40494441986084, + "articlesIDs": [ + "24133628" + ] + }, + { + "text": "intracranial volume (icv) (as a proxy for lifetime maximum brain size)", + "score": 10.397525787353516, + "articlesIDs": [ + "36029398" + ] + }, + { + "text": "with later menarche and menopause", + "score": 10.388063430786133, + "articlesIDs": [ + "21359526" + ] + }, + { + "text": "drd5 (p = 3.0 × 10-79), wdr1 (p = 8.4 × 10-77), nomo1", + "score": 10.375044822692871, + "articlesIDs": [ + "28339748" + ] + }, + { + "text": "subfalcine and/or subtentorial herniation", + "score": 10.37153434753418, + "articlesIDs": [ + "21954970" + ] + }, + { + "text": "heterozygous g/t carriers", + "score": 10.36704158782959, + "articlesIDs": [ + "23096687" + ] + }, + { + "text": "among large-for-gestational-age children", + "score": 10.361839294433594, + "articlesIDs": [ + "28219020" + ] + }, + { + "text": "nomo1 (p = 1.3 × 10-25), and pdxdc1", + "score": 10.357402801513672, + "articlesIDs": [ + "28339748" + ] + }, + { + "text": "the rad52 rs7963551 snp", + "score": 10.357242584228516, + "articlesIDs": [ + "25012956" + ] + }, + { + "text": "metabolic syndrome", + "score": 10.352880477905273, + "articlesIDs": [ + "35096403" + ] + }, + { + "text": "widowed group", + "score": 10.34415054321289, + "articlesIDs": [ + "30593203" + ] + }, + { + "text": "\"cagt\" haplotype of the gene", + "score": 10.34097957611084, + "articlesIDs": [ + "31486713" + ] + }, + { + "text": "patients with glioma grade ii-iii and epilepsy", + "score": 10.340200424194336, + "articlesIDs": [ + "30471051" + ] + }, + { + "text": "female than male patients (14.0 vs. 8.0%). depression in males", + "score": 10.339834213256836, + "articlesIDs": [ + "32876766" + ] + }, + { + "text": "vzv-unique protein orf2p", + "score": 10.337324142456055, + "articlesIDs": [ + "24127236" + ] + }, + { + "text": "the variant il-12p40 1188c/a genotype", + "score": 10.335214614868164, + "articlesIDs": [ + "26516307" + ] + }, + { + "text": "patients with known cerebrovascular disease. increasing age", + "score": 10.330963134765625, + "articlesIDs": [ + "34468884" + ] + }, + { + "text": "frequency of the a mutant allele of icam-1 r241g", + "score": 10.325780868530273, + "articlesIDs": [ + "24289603" + ] + }, + { + "text": "the frequency of the a mutant allele of icam-1 r241g", + "score": 10.319826126098633, + "articlesIDs": [ + "24289603" + ] + }, + { + "text": "mobile phones (mps)", + "score": 10.315604209899902, + "articlesIDs": [ + "30633716" + ] + }, + { + "text": "subjects exposed to extremely low-frequency electromagnetic fields", + "score": 10.306023597717285, + "articlesIDs": [ + "28401165" + ] + }, + { + "text": "poly(adp-ribose) polymerase-1 (parp-1)", + "score": 10.305218696594238, + "articlesIDs": [ + "28777431" + ] + }, + { + "text": ", having 30 or more pack-years of smoking over the course of one's lifetime", + "score": 10.298401832580566, + "articlesIDs": [ + "32466105" + ] + }, + { + "text": "insulin-like growth factor-1 (igf-1)", + "score": 10.294998168945312, + "articlesIDs": [ + "34564026" + ] + }, + { + "text": "atypical teratoid/rhabdoid tumor (atrt)", + "score": 10.293781280517578, + "articlesIDs": [ + "31281481" + ] + }, + { + "text": "experienced glioma-related seizures", + "score": 10.282047271728516, + "articlesIDs": [ + "35326529" + ] + }, + { + "text": "the gm 3/17 genotype and the combination of gm 3 and gm 3/17", + "score": 10.27681827545166, + "articlesIDs": [ + "25097800" + ] + }, + { + "text": "n-nitrosamines", + "score": 10.270788192749023, + "articlesIDs": [ + "21434862" + ] + }, + { + "text": "the a allele of the icam-1 r241g gene polymorphism", + "score": 10.267991065979004, + "articlesIDs": [ + "24289603" + ] + }, + { + "text": "the \"engineer, architect\" occupational group", + "score": 10.26152229309082, + "articlesIDs": [ + "22715102" + ] + }, + { + "text": "younger vs older ages at exposure", + "score": 10.249773025512695, + "articlesIDs": [ + "22952197" + ] + }, + { + "text": "patients with type i neurofibromatosis (nf1)", + "score": 10.248650550842285, + "articlesIDs": [ + "25381154" + ] + }, + { + "text": "the cxcl12 g801a polymorphism", + "score": 10.244407653808594, + "articlesIDs": [ + "26782381" + ] + }, + { + "text": "7p11.2 which encompasses the egfr gene", + "score": 10.24385929107666, + "articlesIDs": [ + "21531791" + ] + }, + { + "text": "treh, il4r and ccdc26", + "score": 10.23477554321289, + "articlesIDs": [ + "22369735" + ] + }, + { + "text": "7-alpha-hydroxy-3-oxo-4-cholestenoate", + "score": 10.23315143585205, + "articlesIDs": [ + "35958335" + ] + }, + { + "text": "moderate-to-high frailty", + "score": 10.231311798095703, + "articlesIDs": [ + "33222979" + ] + }, + { + "text": "arg399gln (rs25487) polymorphisms in xrcc1 gene", + "score": 10.230796813964844, + "articlesIDs": [ + "25245010" + ] + }, + { + "text": "gh-treated survivors", + "score": 10.230791091918945, + "articlesIDs": [ + "24606096" + ] + }, + { + "text": "among rs2910164 minor allele (c) carriers", + "score": 10.23055648803711, + "articlesIDs": [ + "21744077" + ] + }, + { + "text": "several vegfa polymorphisms", + "score": 10.226924896240234, + "articlesIDs": [ + "29137376" + ] + }, + { + "text": ", ever statin use (hr = 1.43, 95% ci 1.10-1.86) and statin use duration", + "score": 10.214792251586914, + "articlesIDs": [ + "31559554" + ] + }, + { + "text": "among individuals born with a large head circumference", + "score": 10.213789939880371, + "articlesIDs": [ + "26823476" + ] + }, + { + "text": "the aa genotype of ercc1 c8092a polymorphism", + "score": 10.209123611450195, + "articlesIDs": [ + "24763305" + ] + }, + { + "text": "a history of 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