diff --git "a/H00017.json" "b/H00017.json" new file mode 100644--- /dev/null +++ "b/H00017.json" @@ -0,0 +1,6942 @@ +{ + "id": "H00017", + "disease": { + "id": "H00017", + "names": [ + "Esophageal cancer" + ], + "dbLinks": { + "icd10": [ + "C15" + ], + "mesh": [ + "D004938" + ] + }, + "category": "Cancer" + }, + "riskFactors": [ + { + "text": "exposure to indoor air pollution", + "score": 14.33796501159668, + "articlesIDs": [ + "30611753" + ] + }, + { + "text": "drinking unpiped water", + "score": 14.334209442138672, + "articlesIDs": [ + "30611753" + ] + }, + { + "text": "drinking hot tea (≥60°c)", + "score": 14.310582160949707, + "articlesIDs": [ + "30611753" + ] + }, + { + "text": "excessive tooth loss (hr 1.66; 95% ci 1.04-2.64), drinking unpiped water", + "score": 14.214836120605469, + "articlesIDs": [ + "30611753" + ] + }, + { + "text": "family history of esophageal adenocarcinoma", + "score": 14.206304550170898, + "articlesIDs": [ + "31080607" + ] + }, + { + "text": "alcohol 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+ "score": 11.790032386779785, + "articlesIDs": [ + "34505256" + ] + }, + { + "text": "low ghrelin concentrations", + "score": 11.785645484924316, + "articlesIDs": [ + "31351006" + ] + }, + { + "text": "type a behavior (or: 1.40, 95% ci: 1.17-1.67), depression", + "score": 11.770164489746094, + "articlesIDs": [ + "34032723" + ] + }, + { + "text": "tobacco chewers", + "score": 11.768449783325195, + "articlesIDs": [ + "32974170" + ] + }, + { + "text": "smoking status, alarming symptoms of retrosternal pain", + "score": 11.767644882202148, + "articlesIDs": [ + "32663318" + ] + }, + { + "text": "heavy smoking, proximal gastrectomy", + "score": 11.764982223510742, + "articlesIDs": [ + "35847443" + ] + }, + { + "text": "treated achalasia patients with symptom recurrence", + "score": 11.760562896728516, + "articlesIDs": [ + "30809653" + ] + }, + { + "text": "hot beverage drinking", + "score": 11.75853157043457, + "articlesIDs": [ + "30891750" + ] + }, + { + "text": "diabetic patients who used metformin", + "score": 11.755844116210938, + "articlesIDs": [ + "37314979" + ] + }, + { + "text": "radiation after surgery; radiation before and after surgery", + "score": 11.746747016906738, + "articlesIDs": [ + "35809269" + ] + }, + { + "text": "reported shorter time from pouring tea to drinking", + "score": 11.746694564819336, + "articlesIDs": [ + "30891750" + ] + }, + { + "text": "human papillomavirus (hpv), epstein-barr virus, and polyoma viruses", + "score": 11.746587753295898, + "articlesIDs": [ + "29851130" + ] + }, + { + "text": "patient with anxiety disorder", + "score": 11.74337387084961, + "articlesIDs": [ + "30264450" + ] + }, + { + "text": "hemoglobin a1c level of ≥7.3%, fib-4 index of ≥1.44", + "score": 11.739670753479004, + "articlesIDs": [ + "34313831" + ] + }, + { + "text": "spicy food 57%, salted food 53%, quid \u0026 tobacco taken orally and through nose", + "score": 11.735494613647461, + "articlesIDs": [ + "35480512" + ] + }, + { + "text": "larger mcv, presence of a slow-metabolizing alcohol dehydrogenase-1b genotype", + "score": 11.722965240478516, + "articlesIDs": [ + "33249700" + ] + }, + { + "text": "thickness of the clavicle, the sternum-trachea distance", + "score": 11.722469329833984, + "articlesIDs": [ + "32611514" + ] + }, + { + "text": "unplanned conversion to open esophagectomy during mie", + "score": 11.716304779052734, + "articlesIDs": [ + "33333084" + ] + }, + { + "text": "atrophic gastritis, a history of partial gastrectomy", + "score": 11.7131929397583, + "articlesIDs": [ + "34236559" + ] + }, + { + "text": "primary tumor localization in the proximal esophagus", + "score": 11.712736129760742, + "articlesIDs": [ + "31517322" + ] + }, + { + "text": "smoking, family history of esophageal cancer", + "score": 11.707897186279297, + "articlesIDs": [ + "36317220" + ] + }, + { + "text": "smoking and family history of esophageal cancer", + "score": 11.69272232055664, + "articlesIDs": [ + "36317220" + ] + }, + { + "text": "low-grade dysplasia (lgd) at baseline", + "score": 11.692007064819336, + "articlesIDs": [ + "34228885" + ] + }, + { + "text": "c allele of rs4143370 and the a allele of rs34904192 in mir155hg", + "score": 11.686616897583008, + "articlesIDs": [ + "36646064" + ] + }, + { + "text": "among patients with t2d", + "score": 11.686220169067383, + "articlesIDs": [ + "31070008" + ] + }, + { + "text": "barrett's esophagus (be)", + "score": 11.678909301757812, + "articlesIDs": [ + "34228885", + "29671158" + ] + }, + { + "text": "betel nut chewing", + "score": 11.66126823425293, + "articlesIDs": [ + "33552962" + ] + }, + { + "text": "high levels of selenium with lower levels of vitamin e", + "score": 11.657909393310547, + "articlesIDs": [ + "37547507" + ] + }, + { + "text": "positive proximal resection margins", + "score": 11.657148361206055, + "articlesIDs": [ + "30239640" + ] + }, + { + "text": "use of drugs 64%, spicy food", + "score": 11.650257110595703, + "articlesIDs": [ + "35480512" + ] + }, + { + "text": "primary school education or below (1.50, 95: 1.20-1.89), drinking groundwater", + "score": 11.633657455444336, + "articlesIDs": [ + "31683395" + ] + }, + { + "text": "heme oxygenase 1", + "score": 11.62272834777832, + "articlesIDs": [ + "34128078" + ] + }, + { + "text": "chagasic megaesophagus and hpv", + "score": 11.616777420043945, + "articlesIDs": [ + "29687834" + ] + }, + { + "text": "male sex, smoking habit", + "score": 11.616218566894531, + "articlesIDs": [ + "35898591" + ] + }, + { + "text": "gpv carriers. similar associations were observed with p16 alteration", + "score": 11.616089820861816, + "articlesIDs": [ + "36269225" + ] + }, + { + "text": "located in the upper esophagus, multiple lvls", + "score": 11.614025115966797, + "articlesIDs": [ + "35788888" + ] + }, + { + "text": "minor calcification of the coronary arteries", + "score": 11.611932754516602, + "articlesIDs": [ + "29452856" + ] + }, + { + "text": "elevated cholesterol", + "score": 11.606367111206055, + "articlesIDs": [ + "33466239" + ] + }, + { + "text": "history of surgery for ec", + "score": 11.602678298950195, + "articlesIDs": [ + "32866561" + ] + }, + { + "text": "alcohol consumers", + "score": 11.602341651916504, + "articlesIDs": [ + "31786674" + ] + }, + { + "text": "smoking, alcohol use, and high body-mass index", + "score": 11.599846839904785, + "articlesIDs": [ + "36910098" + ] + }, + { + "text": "use of drugs 64%, spicy food 57%, salted food", + "score": 11.597007751464844, + "articlesIDs": [ + "35480512" + ] + }, + { + "text": "asa score ≥ 3", + "score": 11.592333793640137, + "articlesIDs": [ + "31438866" + ] + }, + { + "text": "infection by h. pylori without and with expression of caga", + "score": 11.588977813720703, + "articlesIDs": [ + "31376284" + ] + }, + { + "text": "presence of \"multiple small luls (≤ 5 mm)", + "score": 11.564709663391113, + "articlesIDs": [ + "36418206" + ] + }, + { + "text": "western lifestyle reflected by high and very high national hdi levels", + "score": 11.560874938964844, + "articlesIDs": [ + "34563100" + ] + }, + { + "text": "a. actinomycetemcomitans in saliva, as well as a drinking habit", + "score": 11.56046199798584, + "articlesIDs": [ + "33156979" + ] + }, + { + "text": ", low-activity aldh2", + "score": 11.556846618652344, + "articlesIDs": [ + "29707772" + ] + }, + { + "text": "lung cancer, esophageal cancer, pancreatic cancer, hematologic malignancy", + "score": 11.556200981140137, + "articlesIDs": [ + "33145069" + ] + }, + { + "text": "older age at diagnosis, male sex", + "score": 11.552644729614258, + "articlesIDs": [ + "35809269" + ] + }, + { + "text": "lower thoracic segment of the esophagus", + "score": 11.54865837097168, + "articlesIDs": [ + "35117615" + ] + }, + { + "text": "periodontitis in ec patients", + "score": 11.546266555786133, + "articlesIDs": [ + "34505256" + ] + }, + { + "text": "patients carrying four risk snps", + "score": 11.544394493103027, + "articlesIDs": [ + "33552962" + ] + }, + { + "text": "the consumption of hot food or tea and smoked fish", + "score": 11.538068771362305, + "articlesIDs": [ + "34342770" + ] + }, + { + "text": "microbial biofilm, and periodontitis in ec patients", + "score": 11.536699295043945, + "articlesIDs": [ + "34505256" + ] + }, + { + "text": "male musicians", + "score": 11.533073425292969, + "articlesIDs": [ + "34162315" + ] + }, + { + "text": "type 2 diabetes mellitus (t2dm)", + "score": 11.532490730285645, + "articlesIDs": [ + "29705628", + "36277883" + ] + }, + { + "text": "low baseline ghrelin concentrations", + "score": 11.531174659729004, + "articlesIDs": [ + "31351006" + ] + }, + { + "text": "presence of \"multiple small luls (≤ 5 mm)\"", + "score": 11.518945693969727, + "articlesIDs": [ + "36418206" + ] + }, + { + "text": "quartile 4 (≥0.89 mmol/l", + "score": 11.508013725280762, + "articlesIDs": [ + "33271534" + ] + }, + { + "text": "ever-alcohol consumption", + "score": 11.507011413574219, + "articlesIDs": [ + "31786674" + ] + }, + { + "text": "smoking and excessive caloric intake", + "score": 11.506162643432617, + "articlesIDs": [ + "33586344" + ] + }, + { + "text": "cyp2e1", + "score": 11.502429008483887, + "articlesIDs": [ + "30362092" + ] + }, + { + "text": "cytochrome p4501a1 ( rs4646903 t\u003ec polymorphism", + "score": 11.502328872680664, + "articlesIDs": [ + "31423187" + ] + }, + { + "text": "obese individuals", + "score": 11.501876831054688, + "articlesIDs": [ + "32441160" + ] + }, + { + "text": "persistent high-risk human papillomavirus (hpv)", + "score": 11.498880386352539, + "articlesIDs": [ + "29687834" + ] + }, + { + "text": "20 nmol/l increase in genetically estimated 25(oh)d concentration", + "score": 11.497697830200195, + "articlesIDs": [ + "30716477" + ] + }, + { + "text": "the presence of afibrotic ila", + "score": 11.488059043884277, + "articlesIDs": [ + "37191186" + ] + }, + { + "text": "obesity and chronic gastroesophageal reflux disease (gerd)", + "score": 11.48766040802002, + "articlesIDs": [ + "33441691" + ] + }, + { + "text": "locally made alcohol", + "score": 11.486700057983398, + "articlesIDs": [ + "34342770" + ] + }, + { + "text": "people with frequent symptoms of gastroesophageal reflux, in smokers", + "score": 11.479042053222656, + "articlesIDs": [ + "29671158" + ] + }, + { + "text": "p16 and p14arf alteration on cancer risk. smoking", + "score": 11.477888107299805, + "articlesIDs": [ + "36269225" + ] + }, + { + "text": "hematologic malignancy and head and neck cancer", + "score": 11.474100112915039, + "articlesIDs": [ + "33145069" + ] + }, + { + "text": "hereditary variations in aldh2, cish, ercc5, and adh1b", + "score": 11.469640731811523, + "articlesIDs": [ + "33552962" + ] + }, + { + "text": "persistent high-risk human papillomavirus (hpv) infection", + "score": 11.464323997497559, + "articlesIDs": [ + "29687834" + ] + }, + { + "text": "heavy alcohol consumers", + "score": 11.460575103759766, + "articlesIDs": [ + "35788888" + ] + }, + { + "text": "women with the behavior of eating anything at any time", + "score": 11.45238971710205, + "articlesIDs": [ + "34293086" + ] + }, + { + "text": "absence of thoracic epidural anesthesia (tea)", + "score": 11.445091247558594, + "articlesIDs": [ + "31438866" + ] + }, + { + "text": "advanced clinical t stage", + "score": 11.439258575439453, + "articlesIDs": [ + "34801263" + ] + }, + { + "text": "stx16, and gspa", + "score": 11.43311882019043, + "articlesIDs": [ + "34128078" + ] + }, + { + "text": "presence of \"multiple small luls (≤ 5 mm)\" in chromoendoscopy", + "score": 11.432022094726562, + "articlesIDs": [ + "36418206" + ] + }, + { + "text": "obesity and smoking in females", + "score": 11.431421279907227, + "articlesIDs": [ + "34855123" + ] + }, + { + "text": "human papilloma virus (hpv)", + "score": 11.417854309082031, + "articlesIDs": [ + "35681587", + "30249500" + ] + }, + { + "text": "polymorphism of gsts genes", + "score": 11.410709381103516, + "articlesIDs": [ + "32488710" + ] + }, + { + "text": "those with intermediate sleep", + "score": 11.405496597290039, + "articlesIDs": [ + "37195052" + ] + }, + { + "text": "patients with cancers of the digestive system", + "score": 11.39261531829834, + "articlesIDs": [ + "29956393" + ] + }, + { + "text": "the c allele of rs4143370 and the a allele of rs34904192 in mir155hg", + "score": 11.39195442199707, + "articlesIDs": [ + "36646064" + ] + }, + { + "text": "the rs1042522 arg allele carriers who also smoked or consumed alcohol", + "score": 11.38273811340332, + "articlesIDs": [ + "33290139" + ] + }, + { + "text": "the width of the gastric conduit", + "score": 11.379880905151367, + "articlesIDs": [ + "32683957" + ] + }, + { + "text": "long standing gastroesophageal reflux disease", + "score": 11.377908706665039, + "articlesIDs": [ + "32462190" + ] + }, + { + "text": "tobacco smoking, alcohol drinking", + "score": 11.367178916931152, + "articlesIDs": [ + "33489898" + ] + }, + { + "text": "having anxiety disorder", + "score": 11.366098403930664, + "articlesIDs": [ + "30264450" + ] + }, + { + "text": "chronic obstructive pulmonary disease (copd)", + "score": 11.362804412841797, + "articlesIDs": [ + "35948471" + ] + }, + { + "text": "male (odds ratio 13.3) and moderate/severe atrophic gastritis", + "score": 11.360261917114258, + "articlesIDs": [ + "33630192" + ] + }, + { + "text": "chronic reflux", + "score": 11.36004638671875, + "articlesIDs": [ + "36892169" + ] + }, + { + "text": "melancholy (or: 2.06, 95% ci: 1.32-3.20), always in sulks", + "score": 11.358447074890137, + "articlesIDs": [ + "34032723" + ] + }, + { + "text": "fewer remaining teeth at baseline", + "score": 11.348464012145996, + "articlesIDs": [ + "35477184" + ] + }, + { + "text": "higher dietary intakes of vitamin b12 and methionine", + "score": 11.347169876098633, + "articlesIDs": [ + "34470601" + ] + }, + { + "text": "those with mets and at high genetic risk", + "score": 11.345612525939941, + "articlesIDs": [ + "35730595" + ] + }, + { + "text": "age categories \u003c 65, 65-74, and ≥ 75 years", + "score": 11.344297409057617, + "articlesIDs": [ + "36125625" + ] + }, + { + "text": "hp1-1 genotype was the most prevalent genotype", + "score": 11.337139129638672, + "articlesIDs": [ + "31653132" + ] + }, + { + "text": "located in the upper esophagus, multiple lvls and history of hnscc", + "score": 11.327558517456055, + "articlesIDs": [ + "35788888" + ] + }, + { + "text": "in male musicians", + "score": 11.324153900146484, + "articlesIDs": [ + "34162315" + ] + }, + { + "text": "adults 50 years or older with obesity", + "score": 11.323322296142578, + "articlesIDs": [ + "32352680" + ] + }, + { + "text": "hpv-16/18", + "score": 11.320816040039062, + "articlesIDs": [ + "34273005" + ] + }, + { + "text": "slc39a6, igf1, sema5b, xrcc3, nqo1 and ogg1 polymorphisms", + "score": 11.308023452758789, + "articlesIDs": [ + "32864859" + ] + }, + { + "text": "obese i (bmi 25-29.9 kg/m) individuals, abdominal obesity", + "score": 11.30728816986084, + "articlesIDs": [ + "31792601" + ] + }, + { + "text": "patients with esophageal adenocarcinoma", + "score": 11.292107582092285, + "articlesIDs": [ + "30655068" + ] + }, + { + "text": "hyperfractionated radiotherapy", + "score": 11.29032039642334, + "articlesIDs": [ + "35209855" + ] + }, + { + "text": "increasing tumor size", + "score": 11.283010482788086, + "articlesIDs": [ + "31323215" + ] + }, + { + "text": "household burning of biomass or kerosene, especially without a chimney,", + "score": 11.265296936035156, + "articlesIDs": [ + "32609005" + ] + }, + { + "text": "hcc", + "score": 11.264732360839844, + "articlesIDs": [ + "34377034" + ] + }, + { + "text": "patients with untreated hypertension", + "score": 11.26461410522461, + "articlesIDs": [ + "32581314" + ] + }, + { + "text": "tobacco smoking and excessive alcohol consumption", + "score": 11.263988494873047, + "articlesIDs": [ + "32056165" + ] + }, + { + "text": "the thickness of the clavicle, the sternum-trachea distance", + "score": 11.263616561889648, + "articlesIDs": [ + "32611514" + ] + }, + { + "text": "high c-reactive protein (crp)", + "score": 11.262856483459473, + "articlesIDs": [ + "36941500" + ] + }, + { + "text": "1-3 days/week and 1.15 (1.00-1.31) for regular consumers (≥4 days/week)", + "score": 11.261041641235352, + "articlesIDs": [ + "37020268" + ] + }, + { + "text": "patients undergoing esophagectomy for benign disease", + "score": 11.241747856140137, + "articlesIDs": [ + "36126720" + ] + }, + { + "text": "age, t stage, ulcerative esophageal cancer", + "score": 11.229545593261719, + "articlesIDs": [ + "35209855" + ] + }, + { + "text": "proton pump inhibitor use", + "score": 11.216436386108398, + "articlesIDs": [ + "34236559" + ] + }, + { + "text": "subjects with the g genotype", + "score": 11.215742111206055, + "articlesIDs": [ + "31970867" + ] + }, + { + "text": "among current arrack consumers", + "score": 11.215309143066406, + "articlesIDs": [ + "34507085" + ] 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