A new text mining tool was developed and used to identify peptide sequences in MEDLINE abstracts. These data were combined with two of the public sources of peptide sequence data, ASPD and UniProt, as well as with peptide data that are manually curated from abstracts and full text articles.
http://pepbank.mgh.harvard.edu/
The sequence of amino acids in a protein or polypeptide is known as the primary structure. The primary structure will determine how the polypeptide will fold.
https://quizlet.com/2774225/protein-structure-flash-cards/
Translation is the process that takes the information passed from DNA as messenger RNA and turns it into a series of amino acids bound together with peptide bonds. It is essentially a translation from one code (nucleotide sequence) to another code (amino acid sequence).
http://serc.carleton.edu/microbelife/research_methods/genomics/translat.html
PepBank is a database of peptides based on sequence text mining and public peptide data sources. Only peptides that are 20 amino acids or shorter are stored. Only peptides with available sequences are stored.
http://pepbank.mgh.harvard.edu/
Tertiary structure. The three-dimensional structure of a protein. A polypeptide is a molecule made from a large number of amino acids joined by condensation. This polypeptide is folded to form a protein. Some sections of the polypeptide coil and fold to produce the secondary structure of the protein. The whole protein then folds into a specific three-dimensional shape known as the tertiary structure.
https://quizlet.com/2774225/protein-structure-flash-cards/
1 tRNA-transfer RNA is a small RNA that has a very specific secondary and tertiary structure such that it can bind an amino acid at one end, and mRNA at the other end. 2  It acts as an adaptor to carry the amino acid elements of a protein to the appropriate place as coded for by the mRNA.
http://serc.carleton.edu/microbelife/research_methods/genomics/translat.html
1 The mRNA acts as a busboy to carry the information stored in the DNA in the nucleus to the cytoplasm where the ribosomes can make it into protein. 2  tRNA-transfer RNA is a small RNA that has a very specific secondary and tertiary structure such that it can bind an amino acid at one end, and mRNA at the other end.
http://serc.carleton.edu/microbelife/research_methods/genomics/translat.html
1 Each time a new tRNA comes into the ribosome, the amino acid that it was carrying gets added to the elongating polypeptide chain. 2  The ribosome continues until it hits a stop sequence, then it releases the polypeptide and the mRNA.
http://serc.carleton.edu/microbelife/research_methods/genomics/translat.html
1 mRNA-messenger RNA is a copy of a gene. 2  It acts as a photocopy of a gene by having a sequence complementary to one strand of the DNA and identical to the other strand. 3  The mRNA acts as a busboy to carry the information stored in the DNA in the nucleus to the cytoplasm where the ribosomes can make it into protein.
http://serc.carleton.edu/microbelife/research_methods/genomics/translat.html
Version 2 (October 2009) [PubMed] [Full text]. The heat map can be used to navigate the results. Entries are automatically classified into predefined categories of interest, for example: related to cancer, have binding data available, etc, using a machine learning algorithm. The users are able to vote.
http://pepbank.mgh.harvard.edu/
what is a polypeptide a sequence of
A Polypeptide is a sequence of Amino acids. A polypeptide is a sequence of amino acids.