(2) Creatine is known to be processed by the kidneys, and the metabolite (break down product) known as creatinine can be measured in urine. Ingesting creatine will increase the amount of creatinine in the urine, which makes sense since you're consuming something that is broken down and needs to be processed from the body.
https://examine.com/nutrition/does-creatine-cause-kidney-problems/
Elevated creatinine level signifies impaired kidney function or kidney disease. As the kidneys become impaired for any reason, the creatinine level in the blood will rise due to poor clearance of creatinine by the kidneys.
https://www.medicinenet.com/creatinine_blood_test/article.htm
There is even evidence where in situations where the kidneys do not function optimally, such as this study in a man taking a large dose of creatine (20 grams) while only having one kidney functioning, there is still no damage seen.
https://examine.com/nutrition/does-creatine-cause-kidney-problems/
Creatinine is a chemical waste molecule that is generated from muscle metabolism. Creatinine is produced from creatine, a molecule of major importance for energy production in muscles. Approximately 2% of the body's creatine is converted to creatinine every day. Creatinine is transported through the bloodstream to the kidneys. The kidneys filter out most of the creatinine and dispose of it in the urine.
https://www.medicinenet.com/creatinine_blood_test/article.htm
The only potential harm from creatine on the kidneys, which is currently theoretical (based on case studies), are in cases where somebody has a kidney disorder that is being treated with diuretics.
https://examine.com/nutrition/does-creatine-cause-kidney-problems/
Creatinine blood test is a test that measures kidney function. Learn what the results of the creatinine blood test mean and how abnormal creatinine levels in the blood may indicate kidney disease or kidney damage.
https://www.medicinenet.com/creatinine_blood_test/article.htm
Does creatine cause kidney problems? Studies looking at creatine and the kidneys have failed to demonstrate any harm from supplementation (except for some plausible interactions with diuretic pharmaceuticals).
https://examine.com/nutrition/does-creatine-cause-kidney-problems/
Aside from a plausible interaction with diuretic pharmaceuticals, studies looking at creatine and the kidneys have failed to demonstrate any harm from supplementation.
https://examine.com/nutrition/does-creatine-cause-kidney-problems/
Creatine is going to meet the kidneys eventually if it is managed to be absorbed from the intestines (2) Creatine is known to be processed by the kidneys, and the metabolite (break down product) known as creatinine can be measured in urine Ingesting creatine will increase the amount of creatinine in the urine, which makes sense since you're consuming something that is broken down and needs to be processed from the body.
https://examine.com/nutrition/does-creatine-cause-kidney-problems/
However, measuring creatinine in the urine used to be the gold standard of assessing kidney damage; does the increase in creatinine seen with creatine supplementation mean that the kidneys are being damaged or does it an observation error? The Evidence
https://examine.com/nutrition/does-creatine-cause-kidney-problems/
what is creatine in the kidneys
Creatinine is a chemical waste molecule that is generated from muscle metabolism.