May 2, 2016 – Takeda Pharmaceuticals U.S.A., Inc. and Lundbeck announced that Brintellix (vortioxetine) will be marketed in the United States under the new name Trintellix (vortioxetine) effective June 2016.
https://www.drugs.com/trintellix.html
Important Safety Information. Antidepressants may increase suicidal thoughts or actions in some children, teens or young adults within the first few months of treatment or when the dose is changed. Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions.
https://us.trintellix.com/important-safety-information
What is Trintellix? Trintellix (vortioxetine) is an antidepressant that affects chemicals in the brain that may be unbalanced. Trintellix is used to treat major depressive disorder in adults. Trintellix may also be used for purposes not listed in this medication guide.
https://www.drugs.com/trintellix.html
These studies did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in patients over age 24; there was a trend toward reduced risk with antidepressant use in patients aged 65 and older [see WARNINGS AND PRECAUTIONS].
http://www.rxlist.com/brintellix-drug.htm
To make sure Trintellix is safe for you, tell your doctor if you have: bipolar disorder (manic depression), or a history of drug abuse or suicidal thoughts; liver disease; narrow-angle glaucoma; seizures or epilepsy; bleeding or blood clotting disorder; low levels of sodium in your blood;
https://www.drugs.com/trintellix.html
Pharmacokinetics[edit] Vortioxetine reaches peak plasma concentration (Cmax) within 7 to 11 hours post-administration (Tmax), and its mean terminal half-life ( T⁄1/2) is ≈ 66 hours. Steady-state plasma concentrations are typically reached within two weeks. It has no active metabolites (i.e. it is not a prodrug).
https://en.wikipedia.org/wiki/Vortioxetine
10mg tablets of brand-name vortioxetine (Trintellix, formerly known as Brintellix). Vortioxetine was discovered by scientists at Lundbeck who reported the rationale and synthesis for the drug (then called Lu AA21004) in a 2011 paper.
https://en.wikipedia.org/wiki/Vortioxetine
Placebo Effect in Depression Treatment ». A placebo is a substance, such as a pill or shot, that doesn't contain any active medicine. Scientists typically use placebos as controls in research studies. This helps them understand how much of a medicine's effects are due to the drug itself,...
http://www.rxlist.com/brintellix-drug.htm
Vortioxetine (trade names Trintellix, Brintellix) is an atypical antidepressant (a serotonin modulator and stimulator) made by Lundbeck and Takeda.
https://en.wikipedia.org/wiki/Vortioxetine
The structural formula is: Vortioxetine HBr is a white to very slightly beige powder that is slightly soluble in water. Each BRINTELLIX tablet contains 6.355 mg, 12.71 mg, 19.065 mg, or 25.42 mg of vortioxetine HBr equivalent to 5 mg, 10 mg, 15 mg, or 20 mg of vortioxetine, respectively.
http://www.rxlist.com/brintellix-drug.htm
what is the half life of trintellix
The half life of Trintellix is 66 hours.