Although the precise cause of PMS and PMDD is unknown, it is believed that these conditions result from the interaction of hormones produced by the ovaries at different stages in the menstrual cycle (such as estrogen and progesterone) with the neurotransmitters (chemicals that serve as messengers) in the brain.
http://www.medicinenet.com/premenstrual_dysphoric_disorder_pmdd/page2.htm
In women with major depressive disorder, bipolar disorder, or dysthymia, the symptoms can worsen during the luteal phase, thereby mimicking PMDD. The participants had PMDD for an average of 15 years. The third drug and the third SSRI approved for PMDD.
http://medical-dictionary.thefreedictionary.com/PMDD
While the ovarian hormone levels are normal in women with PMDD, it is likely that the brain's response to these normally-fluctuating hormone levels is abnormal. Most evidence suggests that PMS and PMDD do not result from any specific personality traits or personality types. While stress clearly is associated with PMS and PMDD, it is not considered to be a cause of PMDD. Rather, the associated stress is more likely to be a result of the PMS or PMDD symptoms. Vitamin or other nutritional deficiencies have not been shown to cause PMS or PMDD.
http://www.medicinenet.com/premenstrual_dysphoric_disorder_pmdd/page2.htm
PMDD treatment may require fine tuning. (Selective serotonin reuptake inhibitors) In the PMDD clinical trials, the most common side effects were menstrual irregularities, nausea, headache, breast tenderness, fatigue, irritability, decreased libido, weight gain, and mood changes.
http://medical-dictionary.thefreedictionary.com/PMDD
Schering has recently launched a low dose version of Yasmin,called Yaz which has been approved in the additional indications of acne and PMDD and is forecast to accrue $730m in sales by 2011.
http://medical-dictionary.thefreedictionary.com/PMDD
1 Premenstrual dysphoric disorder (PMDD) can be considered to be a severe form of premenstrual syndrome (PMS), with symptoms that interfere with daily activities and functioning.  PMDD occurs in 3% to 8% of menstruating women.
http://www.medicinenet.com/premenstrual_dysphoric_disorder_pmdd/article.htm
Premenstrual dysphoric disorder (PMDD) Premenstrual syndrome (PMS); symptoms including back and abdominal pain, nervousness and irritability, headache, and breast tenderness that occur the week before menstruation.
http://medical-dictionary.thefreedictionary.com/PMDD
Premenstrual dysphoric disorder (PMDD) can be considered a severe form of premenstrual syndrome (PMS). Both PMS and PMDD are characterized by unpleasant physical and psychological symptoms that occur in the second half of a woman's menstrual cycle, most commonly in the days preceding the menstrual period.
http://www.medicinenet.com/premenstrual_dysphoric_disorder_pmdd/article.htm
The dosing schedule approved for controlled-release paroxerine, marketed as Paxil CE by GlaxoSmithKline, is a daily dose taken continuously throughout the cycle, but the company said that the intermittent dosing for PMDD is under review at the FDA.
http://medical-dictionary.thefreedictionary.com/PMDD
Premenstrual dysphoric disorder (PMDD) facts. Premenstrual dysphoric disorder (PMDD) can be considered to be a severe form of premenstrual syndrome (PMS), with symptoms that interfere with daily activities and functioning.
http://www.medicinenet.com/premenstrual_dysphoric_disorder_pmdd/article.htm
what is pmdd
Premenstrual dysphoric disorder or PMDD can be considered a severe form of premenstrual syndrome or PMS. Premenstrual dysphoric disorder is a severe form of premenstrual syndrome.