Typically, if a significant amount of protein is present, it appears in one of three main patterns. 1  Normally, the glomeruli prevent protein from leaking into the urine.  Normally, some very small proteins can pass through the glomeruli but are removed from the urine by the tubules.
https://labtestsonline.org/understanding/analytes/electrophoresis/tab/test
The condition is often a sign of kidney disease. Healthy kidneys do not allow a significant amount of protein to pass through their filters. But filters damaged by kidney disease may let proteins such as albumin leak from the blood into the urine.
http://www.webmd.com/a-to-z-guides/proteinuria-protein-in-urine
How is it used? Protein electrophoresis is used to identify the presence of abnormal proteins, to identify the absence of normal proteins, and to determine when different groups of proteins are present in unusually high or low amounts in blood or other body fluids.
https://labtestsonline.org/understanding/analytes/electrophoresis/tab/test
Proteinuria can also be a result of overproduction of proteins by the body. Kidney disease often has no early symptoms. One of its first signs may be proteinuria that's discovered by a urine test done during a routine physical exam. Blood tests will then be done to see how well the kidneys are working.
http://www.webmd.com/a-to-z-guides/proteinuria-protein-in-urine
Usually there is very little protein in urine. Typically, if a significant amount of protein is present, it appears in one of three main patterns. Normally, the glomeruli prevent protein from leaking into the urine. When the glomeruli are damaged, albumin and other plasma proteins may leak through and be detected in the urine.
https://labtestsonline.org/understanding/analytes/electrophoresis/tab/test
Risk Factors for Proteinuria. Both diabetes and high blood pressure can cause damage to the kidneys, which leads to proteinuria. Other types of kidney disease unrelated to diabetes or high blood pressure can also cause protein to leak into the urine. Increased production of proteins in the body can lead to proteinuria.
http://www.webmd.com/a-to-z-guides/proteinuria-protein-in-urine
Also known as: Urine protein electrophoresis and UPEP. A urine protein electrophoresis is a test that estimates how much of certain proteins you have in your urine. A clean-catch urine sample is needed. The clean-catch method is used to prevent germs from the penis or vagina from getting into a urine sample.
http://www.scripps.org/articles/3509-protein-electrophoresis-urine
Proteins play an important role in supporting optimal body functioning and health. Proteins are found in the blood of healthy people. However, you shouldn’t have a lot of protein in your urine. Urine protein electrophoresis (UPEP) is a test your doctor can use to determine if there’s protein in your urine. It can also help your doctor find out how much of each type of protein is present. Your doctor will usually order a UPEP test if they suspect that you have a condition that causes elevated protein levels in urine, such as multiple sclerosis or nephrotic syndrome.
http://www.healthline.com/health/protein-s
To complete a UPEP test, you will need to collect a small amount of urine in the container provided. Make sure your genital area is clean. Men should wipe the head of their penis. Women should use soap and water or an antibacterial wipe to clean their vulva.
http://www.healthline.com/health/protein-s
Urine protein electrophoresis may be recommended to help determine the cause of protein in the urine. Or the test may done as a screening test to measure the various amounts of different types of proteins in urine. Urine protein electrophoresis detects two types of protein: albumin and globulins. No significant amount of globulins are found in the urine. Urine albumin is less than 5 mg/dL.
http://www.scripps.org/articles/3509-protein-electrophoresis-urine
what it means significant amount of protein in upep test
In the urine protein electrophoresis test, the significant amount of protein means that estimates how much of certain proteins you have in your urine.