To be on the safe side, always calculate your Folate levels based on your MTHFR mutation. This is one of the reasons why everyone, without exception, should get tested for MTHFR mutations. Otherwise, you will never know if your body has enough levels of Folate to support methylation.
https://www.mthfrdoctors.com/calculate-folate-levels-important/
Put simply, the MTHFR gene triggers the production of MTHFR enzymes. Think of the gene as the flower, the enzyme as the honey-bee, and active folic acid as honey. Without flowers, there will be no honey-bees. Without honey-bees, no honey is created.
https://www.dietvsdisease.org/mthfr-mutation-symptoms-and-diet/
Normal Function. The MTHFR gene provides instructions for making an enzyme called methylenetetrahydrofolate reductase. This enzyme plays a role in processing amino acids, the building blocks of proteins. Methylenetetrahydrofolate reductase is important for a chemical reaction involving forms of the vitamin folate (also called vitamin B9).
https://ghr.nlm.nih.gov/gene/MTHFR
spina bifida. Polymorphisms in the MTHFR gene are also associated with an increased risk of spina bifida, another common type of neural tube defect. In people with this condition, when the spine forms, the bones of the spinal column do not close completely around the developing nerves of the spinal cord.
https://ghr.nlm.nih.gov/gene/MTHFR
One of the more common and potentially dangerous variations is known as an MTHFR mutation. This gene variation can impact how well your body metabolises folate and folic acid. Both are forms of vitamin B9, required for numerous critical bodily functions.
https://www.dietvsdisease.org/mthfr-mutation-symptoms-and-diet/
Folate is a water-soluble B-vitamin, which is also known as vitamin B9 or folacin. Naturally occurring folates exist in many chemical forms; folates are found in food, as well as in metabolically active forms in the human body. Folic acid is the major synthetic form found in fortified foods and vitamin supplements. Other synthetic forms include folinic acid (Figure 1) and levomefolic acid. Folic acid has no biological activity unless converted into folates (1).
http://lpi.oregonstate.edu/mic/vitamins/folate
Vitamin B12 and homocysteine. When you have mthfr gene mutations you lack the enzymes responsible for the conversion of folate that you eat into the active form 5-Methyltetrahydrofolate, this important reaction is then directly involved in the utilization of vitamin B12 which is vitally important in the processing of homocysteine.
https://mthfrgenehealth.com/mthfr-vitamin-b12/
Folate deficiency: A deficiency in folic acid (folate) could be linked to MTHFR and is worth checking out. Common symptoms include extreme fatigue, light-headedness, and forgetfulness. Had a miscarriage: Many alternative practitioners recommend testing for MTHFR mutations if you have had one or more miscarriages.
https://www.dietvsdisease.org/mthfr-mutation-symptoms-and-diet/
It is also known as Vitamin B9. When you read about Folate, think: turning off bad genes and detoxify your body. So, you have the results of your MTHFR (a gene that processes Folate or Folic Acid) test in your hands, and you would like to know how much Methylfolate (the usable form of Folate or Folic Acid) to take.
https://www.mthfrdoctors.com/calculate-folate-levels-important/
Folate is a generic term referring to both natural folates in food and folic acid, the synthetic form used in supplements and fortified food. Folate is critical in the metabolism of nucleic acid precursors and several amino acids, as well as in methylation reactions.
http://lpi.oregonstate.edu/mic/vitamins/folate
which folate is known as mthfr
Methylenetetrahydrofolate is the folate known as MTHFR.