Less commonly, single quotation marks are used in place of parentheses, in which case the translation is not set off with commas. Also, any punctuation otherwise required by the structure of the sentence is placed outside the single quotation marks.
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Quotation marks. Quotation marks are primarily used to indicate material that is being reproduced word for word, as well as some other important uses. This entry consists of the following sections: Quotation marks and adjacent punctuation. Quoting the words of others. Run-in quotations.
http://www.thepunctuationguide.com/quotation-marks.html
Use a comma in the following cases: 1  After an introductory clause. 2  After a long introductory prepositional phrase or more than one introductory prepositional phrase. 3  After introductory verbal phrases, some appositive phrases, or absolute phrases.  If there is a distinct 1  pause. To avoid confusion.
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Some modifying elements of a sentence are essential, restricting the meaning of a modified term, while others are nonessential and don't restrict the modified term's meaning. These nonessential elements, which can be words, phrases, or clauses, are set off with commas. Rule: Use commas before and after nonessential words, phrases, and clauses, that is, elements embedded in the sentence that interrupt it without changing the essential meaning.
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The comma is the punctuation mark most likely to cause angst. This is largely the result of the many different ways the comma is used. Sometimes, the comma indicates a pause that would occur if the sentence were spoken aloud. Other times, the comma separates grammatical components of the sentence.
https://www.thepunctuationguide.com/comma.html
When not to use a comma. Some introductory elements don't require a comma, and sometimes the subject of a sentence looks like an introductory element but isn't. Do not use a comma in the following cases: After a brief prepositional phrase.
https://owl.english.purdue.edu/owl/resource/607/03
Nonessential elements are always offset with commas. The commas dictate a pause when you are reading the sentence or speaking it out loud. If the word, phrase or clause is easily removed from the sentence or moved to another spot within the sentence, the clause is set off with commas on each side. Likewise, if the element interrupts the flow of the sentence, offsetting commas are used. Example 1:
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Comma is required to set apart an introductory phrase. Weegy: Comma is required to set apart an introductory phrase. Weegy: COMMA is not an option for joining two independent clauses to make a compound sentence. User: When the fashion critics witness the unveiling of the designer's latest line of shoes, they will shower her with much deserved praise.
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which punctuation mark is required to set apart an introductory phrase?
The comma punctuation mark is required to set apart an introductory phrase. The  punctuation mark Comma is  required to set apart an introductory phrase.