Climbazole is an imidazole compound active on most fungi and yeasts (Malassezia pachydermatis). Phytosphingosine salicyloyl is a pro-ceramide that helps restore the skin barrier, and also has anti-in ammatory properties.
http://www.entirelypets.com/douxo-antiseptic-chlorhexidine-climbazole-mousse.html
The SCCP is of the opinion that the use of Climbazole as a preservative at a maximum concentration of 0.5% in all cosmetic products cannot be considered safe. However, when used as a preservative in hair cosmetics and face cosmetics at 0.5%, climbazole does not pose a risk to the health of the consumer.
http://ec.europa.eu/health/ph_risk/committees/04_sccp/docs/sccp_o_164.pdf
SCCP/1204/08 Opinion on climbazole 10 3.3. Toxicological evaluation 3.3.1. Acute toxicity 3.3.1.1. Acute oral toxicity Taken from SCCP/0981/05 LD 50 -oral-rat = 400 mg/kg bw (334 - 481 mg/kg bw). LD 50 -oral-mouse = 664 mg/kg bw (572 - 797 mg/kg bw).
http://ec.europa.eu/health/ph_risk/committees/04_sccp/docs/sccp_o_164.pdf
with phytosphingosine, is a no-bathing antiseptic leave-on Mousse that makes treating your pet an enjoyable experience. Chlorhexidine has a strong bactericidal and bacteriostatic activity on the Gram positive and Gram negative bacteria.
http://www.entirelypets.com/douxo-antiseptic-chlorhexidine-climbazole-mousse.html
SCCP/1204/08 Opinion on climbazole 2 About the Scientific Committees Three independent non-food Scientific Committees provide the Commission with the scientific advice it needs when preparing policy and proposals relating to consumer safety, public health and the environment.
http://ec.europa.eu/health/ph_risk/committees/04_sccp/docs/sccp_o_164.pdf
SCCP/1204/08 Opinion on climbazole 11 Each volunteer received one application of the test and control material under semi-occlusive conditions for 24 hours. The sites were graded 30-60 minutes and 24 hours following patch removal.
http://ec.europa.eu/health/ph_risk/committees/04_sccp/docs/sccp_o_164.pdf
It is most commonly found as an active ingredient in OTC anti-dandruff and anti-fungal products, including shampoos, lotions and conditioners. It may be accompanied by other active ingredients such as zinc pyrithione or triclosan.
https://en.wikipedia.org/wiki/Climbazole
Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff and eczema. Climbazole has shown a high in vitro and in vivo efficacy against Pityrosporum ovale that appears to play an important role in the pathogenesis of dandruff. Its chemical structure and properties are similar to other fungicides such as ketoconazole and miconazole.
https://en.wikipedia.org/wiki/Climbazole
OK but makes coat sticky by Cody 05/07/2013. I bought this mousse to go with the douxo shampoo that I use once a week on my dog. The mousse is probably a good product but makes their coat sticky and gummy which feels gross when you pet your dog. The product says it can be used in one spot or all over if needed.
http://www.entirelypets.com/douxo-antiseptic-chlorhexidine-climbazole-mousse.html
Submission II concerned the use of Climbazole as an anti-dandruff active ingredient in hair care formulations up to a maximum concentration of 2.0 % in rinse-off products and as a preservative up to a maximum concentration of 0.5 % in cosmetic products.
http://ec.europa.eu/health/ph_risk/committees/04_sccp/docs/sccp_o_164.pdf
what is climbazole
Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff and eczema.