More about complement. 1  activation pathways (in immune system: Activation of the complement system) 2  disease (in human disease: The immune response) (in human disease: Immune deficiencies) 3  evolution (in immune system: Immune capacity among vertebrates) 4  role in immune system (in immune system: Complement)
https://www.britannica.com/science/complement-immune-system-component
Complement system The term was first used for a heat labile factor in serum that caused immune cytolysis of antibody coated cells; it now refers to the entire functionally related system comprising ± 25 distinct serum proteins, which mediate the nonspecific inflammatory response to various antigens through a complex sequence of enzymatic cleavages; complement is thus the effector not only of immune cytolysis but also of other biologic functions; it is activated by 2 routes, the classic and ...
https://medical-dictionary.thefreedictionary.com/complement
C3b helps bring about the elimination of the microbial invader in two ways: 1  Bound C3b activates the formation of membrane attack complexes, structures composed of other complement proteins that poke holes into the membrane of the invading microorganism and allow the contents of the cell to leak out and the cell to die.
https://www.britannica.com/science/complement-immune-system-component
The activity of complement components is modulated by a system of regulatory proteins that prevent tissue damage as a result of inadvertent binding of activated complement components to host cells or spontaneous activation of complement components in plasma.
https://www.ncbi.nlm.nih.gov/books/NBK27100/
The signal sets off a chemical chain reaction in which one activated complement protein triggers the activation of the next complement protein in the sequence. Complement activation occurs by two routes, called the classical pathway and the alternative pathway, or properdin system.
https://www.britannica.com/science/complement-immune-system-component
(2) Complement system—first used for a heat-labile factor in serum that caused immune cytolysis of antibody coated cells, the complement system now refers to the entire functionally-related system, comprising ± 25 distinct serum proteins that mediate the nonspecific inflammatory response to various antigens through a complex sequence of enzymatic cleavages.
https://medical-dictionary.thefreedictionary.com/complement
complement system. Complement is a term used to denote a group of more than 30 proteins that act in concert to enhance the actions of other defense mechanisms of the body. Complement proteins are produced by liver cells and, in many tissues, by macrophages. Most…
https://www.britannica.com/science/complement-immune-system-component
Complement is a group of at least 20 distinct serum proteins, the activity of which is affected by a series of interactions resulting in enzymatic cleavages; it can follow one or the other of at least two pathways.
https://medical-dictionary.thefreedictionary.com/complement
2-5. Complement is a system of plasma proteins that interacts with pathogens to mark them for destruction by phagocytes. In the early phases of an infection, the complement cascade can be activated on the surface of a pathogen through any one, or more, of the three pathways shown in Fig. 2.8.
https://www.ncbi.nlm.nih.gov/books/NBK27100/
Written By: Complement, in immunology, a complex system of more than 30 proteins that act in concert to help eliminate infectious microorganisms. Specifically, the complement system causes the lysis (bursting) of foreign and infected cells, the phagocytosis (ingestion) of foreign particles and cell debris, and the inflammation of surrounding tissue.
https://www.britannica.com/science/complement-immune-system-component
what is a complement
Complement is a term used to denote a group of more than 30 proteins that act in concert to enhance the actions of other defense mechanisms of the body.