Substances are assigned to one of five toxicity categories, with Category 1 as the most toxic and Category 5 as the least toxic. The table below will give you a better understanding of the Acute Toxicity criteria: Since Category 1 is the highest toxicity category, you can expect the cut-off value to be the lowest of the five categories (e.g. 5mg/kg by the oral route and 50 mg/kg by the dermal route).
http://www.usequantum.com/understanding-acute-toxicity-on-your-ghs-sds/
Understanding Acute Toxicity on your SDS Acute toxicity refers to the adverse effects from either (1) exposure of a single dose of substance, (2) multiple exposures within 24 hours, or (3) inhalation exposure of 4 hours.
http://www.usequantum.com/understanding-acute-toxicity-on-your-ghs-sds/
Acute toxicity is the effect on the human body of either a single exposure or repeated multiple exposures to a compound over a short period of time. Acute toxicity relates to adverse effects that occur within 14 days of exposure.
https://www.safeopedia.com/definition/4798/acute-toxicity
Acute Toxicity Definition - Acute toxicity is the effect on the human body of either a single exposure or repeated multiple exposures to a compound... Acute Toxicity Definition - Acute toxicity is the effect on the human body of either a single exposure or repeated multiple exposures to a compound...
https://www.safeopedia.com/definition/4798/acute-toxicity
The LD50 value, defined as the statistically derived dose that, when administered in an acute toxicity test, is expected to cause death in 50% of the treated animals in a given period, is currently the basis for toxicologic classification of chemicals. For a classical LD50 study, laboratory mice and rats are the species typically selected.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1533392/
These treatment methods include (but are not limited to): 1  Emergency showers used for removing irritating or hazardous chemicals from the skin. 2  Emergency eye washes used for removing any irritating or hazardous chemicals from the eyes. 3  Activated charcoal used to bind and remove harmful substances consumed orally.
https://en.wikipedia.org/wiki/Acute_toxicity
Acute toxicity describes the adverse effects of a substance that result either from a single exposure or from multiple exposures in a short period of time (usually less than 24 hours). To be described as acute toxicity, the adverse effects should occur within 14 days of the administration of the substance. Acute toxicity is distinguished from chronic toxicity, which describes the adverse health effects from repeated exposures, often at lower levels, to a substance over a longer time period (months or years). It is widely considered unethical to use humans as test subjects for acute (or chronic) toxicity research.
https://en.wikipedia.org/wiki/Acute_toxicity
Acute Toxicity. 2. Background. Acute systemic toxicity testing involves an assessment of the general toxic effects of a single dose or multiple doses of a chemical or product, within 24 hours by a particular route (oral, dermal, inhalation), and that occur during a subsequent 21-day observation period.
https://eurl-ecvam.jrc.ec.europa.eu/validation-regulatory-acceptance/systemic-toxicity/acute-toxicity
Understanding Acute Toxicity on your SDS. Acute toxicity refers to the adverse effects from either (1) exposure of a single dose of substance, (2) multiple exposures within 24 hours, or (3) inhalation exposure of 4 hours. Chemicals are categorized into one of five toxicity categories that are expressed in the numerical criteria as either LD50 (oral and dermal) or LC50 (inhalation).
http://www.usequantum.com/understanding-acute-toxicity-on-your-ghs-sds/
This article has been cited by other articles in PMC. The purposes of acute toxicity testing are to obtain information on the biologic activity of a chemical and gain insight into its mechanism of action. The information on acute systemic toxicity generated by the test is used in hazard identification and risk management in the context of production, handling, and use of chemicals.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1533392/
what is acute toxicity
Acute toxicity is the effect on the human body of either a single exposure or repeated multiple exposures to a compound over a short period of time.