duration of action. Therapeutics The length of time that a particular drug is effective. du·ra·tion of ac·tion. (dŭr-ā'shŭn ak'shŭn) The amount of time that a measurable drug effect persists.
http://medical-dictionary.thefreedictionary.com/duration+of+action
As with depression, the action of LSD is not completely understood. There is evidence, however, that serotonergic neurons are involved. LSD is structurally similar to serotonin and seems to affect many of the systems that serotonin has been implicated in (12).
http://serendip.brynmawr.edu/bb/neuro/neuro98/202s98-paper3/Frederickson3.html
Much 'research' has been done into the actual effects of the drug. LSD most profound effect on behavior is the production of sensory distortions, such as hallucinations, and euphoria. It also produces dilated pupils, increased blood pressure, and increased heart rate (7, 9).
http://serendip.brynmawr.edu/bb/neuro/neuro98/202s98-paper3/Frederickson3.html
08540 (U.S.A.) (Accepted December 10th, 1976) SUMMARY LSD elicits a number of emergent behaviors in the cat, including limb flicking, abortive grooming, investigatory and hallucinatory-like behaviors, which we have proposed as an animal behavior model for studying the actions of LSD and related hallucinogens.
http://www.sciencedirect.com/science/article/pii/0006899377904243
Because of the special action of 5-HT2 receptors, antagonism of serotonin at those receptors would result in a decrease in neural activity which would not explain the effects of LSD. If 5-HT2 receptors are in fact excitatory, one would expect antagonism of this system to have an inhibitory effect.
http://serendip.brynmawr.edu/bb/neuro/neuro98/202s98-paper3/Frederickson3.html
These emergent behaviors were used in the present study to investigate the duration of action of LSD, as well as the onset and duration of tolerance. A dose of 10 #g/kg of LSD produced significant behavioral changes for up to 4 h, while a dose of 50 #g/kg produced changes lasting for at least 8 h.
http://www.sciencedirect.com/science/article/pii/0006899377904243
Recreationally used as a hallucinogen and for its ability to alter human perception and mood. Potency, Purity and Dose: The strength of illicit LSD nowadays ranges from 20 to 80 m g per dose, which is considerably less than doses reported during the 1960s and early 1970s, of 100-200 m g or higher per unit. Experienced users typically administer 100-200 m g for a “good high”.
https://www.nhtsa.gov/people/injury/research/job185drugs/lysergic.htm
With moderate doses of blotter LSD, effects start to become noticeable within around half an hour after ingestion, and tend to rise to a peak around 2-5 hours into the experience. After the peak, the trip gradually declines in intensity until one is pretty much back to baseline in around 8-12 hours.
https://erowid.org/chemicals/lsd/lsd_info4.shtml
The duration of action of insulin lispro protamine suspension is between 16 and 18 hours. Nitrous oxide has an onset of action of 3-5 minutes, with a duration of action of 3-5 minutes. Because its duration of action is very short, there's very little continued production of insulin and less risk of hypoglycemia.
http://medical-dictionary.thefreedictionary.com/duration+of+action
LSD is rapidly absorbed after an oral dose and initial symptoms usually appear within a few minutes; visual illusions and perceptual distortions occur within the second or third hour (3). First perception of drug action occurred as late as 2-4 hours after oral doses of DOB in 4 of 13 subjects (2). A pharmacokinetic study (4) showed that DOB (or a metabolite) began to concentrate in the brain only 3 hours after an oral dose. DOB is said (1) to have a longer duration, 12-24 hours, than LSD, 8-12 hours. Both of these characteristics of DOB match those of the drug ingested in Dr. Lake and associates' case --slow onset (3 hours) and a long recovery time (18-24 hours)- as well as or better than do those of LSD.
https://erowid.org/chemicals/dob/dob_journal1.shtml
duration of action lsd
The duration of action Lysergic acid diethylamide  is 8 to 12 hours. The duration of action Lysergsaure diethylamid is 8 to 12 hours.