Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: antipsychotic drugs (such as chlorpromazine, haloperidol, thioridazine), certain drugs used to treat high blood pressure (such as methyldopa, reserpine), tetrabenazine.
http://www.webmd.com/drugs/2/drug-6591/sinemet-oral/details
The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.
http://www.webmd.com/drugs/2/drug-6591/sinemet-oral/details
Sinemet must be used with… read more. Overview. Sinemet is a prescription drug approved by the Food and Drug Administration (FDA) in 1975 to treat motor symptoms of Parkinsonism caused by Parkinson’s Disease, encephalitis, or exposure to carbon monoxide or manganese.
https://www.myparkinsonsteam.com/treatments/sinemet
Sinemet (Levodopa/Carbidopa) Sinemet is a prescription drug approved by the Food and Drug Administration (FDA) in 1975 to treat motor symptoms of Parkinsonism caused by Parkinson’s Disease, encephalitis, or exposure to carbon monoxide or manganese.
https://www.myparkinsonsteam.com/treatments/sinemet
SINEMET (carbidopa-levodopa) is supplied as tablets in three strengths: SINEMET (carbidopa-levodopa) 25-100, containing 25 mg of carbidopa and 100 mg of levodopa. SINEMET (carbidopa-levodopa) 10-100, containing 10 mg of carbidopa and 100 mg of levodopa. SINEMET (carbidopa-levodopa) 25-250, containing 25 mg of carbidopa and 250 mg of levodopa. Inactive ingredients are hydroxypropyl cellulose, pregelatinized starch, crospovidone, microcrystalline cellulose, and magnesium stearate.
http://www.rxlist.com/sinemet-drug.htm
There are two forms of Sinemet, controlled-release or immediate-release Sinemet. Controlled-release (CR) Sinemet and immediate-release Sinemet are equally effective in treating the symptoms of Parkinson's disease, but some people prefer the controlled release version. Ask your doctor which approach is best for you.
http://www.webmd.com/parkinsons-disease/guide/drug-treatments
This combination medication is used to treat symptoms of Parkinson's disease or Parkinson-like symptoms (such as shakiness, stiffness, difficulty moving). Parkinson's disease is thought to be caused by too little of a naturally occurring substance (dopamine) in the brain.
http://www.webmd.com/drugs/2/drug-6591/sinemet-oral/details
Sinemet (Levodopa/Carbidopa) Levodopa (also called L-dopa) is the most commonly prescribed and most effective drug for controlling the symptoms of Parkinson's disease, particularly bradykinesia and rigidity. Levodopa is transported to the nerve cells in the brain that produce dopamine.
http://www.webmd.com/parkinsons-disease/guide/drug-treatments
Sinemet is made up of levodopa and another drug called carbidopa. Levodopa enters the brain and is converted to dopamine while carbidopa increases its effectiveness and prevents or lessens many of the side effects of levodopa, such as nausea, vomiting, and occasional heart rhythm disturbances.
http://www.webmd.com/parkinsons-disease/guide/drug-treatments
Levodopa changes into dopamine in the brain, helping to control movement. Carbidopa prevents the breakdown of levodopa in the bloodstream so more levodopa can enter the brain. Carbidopa can also reduce some of levodopa's side effects such as nausea and vomiting.
http://www.webmd.com/drugs/2/drug-6591/sinemet-oral/details
when was sinemet approved
Sinemet was approved in 1975.