Cofactors can be divided into two broad groups: organic cofactors, such as flavin or heme, and inorganic cofactors, such as the metal ions Mg 2+ , Cu + , Mn 2+ , or iron-sulfur clusters. Organic cofactors are sometimes further divided into coenzymes and prosthetic groups.
https://en.wikipedia.org/wiki/Cofactor_%28biochemistry%29
molecules. The key part of the prosthetic group may be either organic (such as a vitamin vitamin,group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction.
http://encyclopedia2.thefreedictionary.com/prosthetic+group
Feedforward control strategies of subjects with transradial ... by Metzger, Anthony J.; Dromerick, Alexander W.; Schabowsky, Christopher N.; Holley, Rahsaan J.; Monroe / Journal of Rehabilitation Research & Development.
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Heme in health and disease [edit]. Under homeostasis, the reactivity of heme is controlled by its insertion into the “heme pockets” of hemoproteins. Under oxidative stress however, some hemoproteins, e.g. hemoglobin, can release their heme prosthetic groups.
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On the other hand, prosthetic group emphasizes the nature of the binding of a cofactor to a protein (tight or covalent) and, thus, refers to a structural property. Different sources give slightly different definitions of coenzymes, cofactors, and prosthetic groups.
https://en.wikipedia.org/wiki/Cofactor_%28biochemistry%29
Heme (American English) or haem (British English) is a cofactor consisting of an Fe 2+ (ferrous) ion contained in the centre of a large heterocyclic organic ring called a porphyrin, made up of four pyrrolic groups joined together by methine bridges.
https://en.wikipedia.org/wiki/Heme
Not all porphyrins contain iron, but a substantial fraction of porphyrin-containing metalloproteins have heme as their prosthetic group; these are known as hemoproteins.
https://en.wikipedia.org/wiki/Heme
prosthetic group. (biochemistry). A characteristic nonamino acid substance that is strongly bound to a protein and necessary for the protein portion of an enzyme to function; often used to describe the function, as in hemeprotein for hemoglobin.
http://encyclopedia2.thefreedictionary.com/prosthetic+group
prosthetic group. non-amino acid portions of certain protein protein,any of the group of highly complex organic compounds found in all living cells and comprising the most abundant class of all biological molecules. Protein comprises approximately 50% of cellular dry weight...... Click the link for more information.
http://encyclopedia2.thefreedictionary.com/prosthetic+group
The heme ion serves as a source or sink of electrons during electron transfer or redox chemistry. In peroxidase reactions, the porphyrin molecule also serves as an electron source. In the transportation or detection of diatomic gases, the gas binds to the heme ion. During the detection of diatomic gases, the binding of the gas ligand to the heme ion induces conformational changes in the surrounding protein.
https://en.wikipedia.org/wiki/Heme
prosthetic group definition
A prosthetic group is non amino acid portions of certain protein.