amide molecule
Amine, any member of a family of nitrogen-containing organic compounds that is derived, either in principle or in practice, from ammonia (NH3). Definition of Amides: Primary amides are organic chemical compounds that include the functional group: That is, primary* amides are a class or category of organic chemical compounds that include a part consisting of a carbon atom connected to both: 1  a nitrogen atom connected to two hydrogen atoms by single covalent bonds between the nitogen and each of the hydrogen atoms (that is an -amine group). AND. Recall that nitrogen has five valence electrons and therefore requires three electrons or bonds to. complete its octet (see Amine Tutorial). Based on this valence and bonding order, nitrogen forms. three bonds in its neutral state and maintains one pair of non-bonded electrons (NBEs). In amides. Amides are derived from carboxylic acids. A carboxylic acid contains the \(-COOH\) functional group, and in an amide the \(-OH\) part of that group is replaced by an \(-NH_2\) group. So, amides contain the \(-CONH_2\) group. The amide linkage has some interesting properties that may not be obvious from other chemical classes. The term amide refers both to classes of compounds and to the functional group (RnE(O)xNR′2) within those compounds. Amide can also refer to the conjugate base of ammonia (the anion H2N−) or of an organic amine (an anion R2N−). For discussion of these anionic amides, see Alkali metal amides. Definition: An amide is a functional group containing a carbonyl group linked to a nitrogen atom. Amide also refers to any compound containing the amide functional group. Amides are derived from carboxylic acid and an amine. Amide is also the name for the inorganic anion NH2. It is the conjugate base of ammonia (NH3). An amine molecule has the shape of a somewhat flattened triangular pyramid, with the nitrogen atom at the apex. An unshared electron pair is localized above the nitrogen atom. In quaternary ammonium ions this region is occupied by a substituent, forming a nearly regular tetrahedron with the nitrogen atom at its centre. In amides. one of the three bonds is a carbonyl carbon. Thus amides may be viewed as acylated amines or as. derivatives of carboxylic acids in which the -OH of the acid has been replaced by -NR2 where R=. Ascentis RP-Amide HPLC Columns. Ultra-Low Bleed Alkyl Amide Phase that Rivals C18 as a Generic Scouting Column. Excellent Peak Shape and Resolution, Especially for Polar Compounds or Mixtures of Compound Polarity. As pioneers in embedded polar group (EPG) phases for HPLC, Supelco is pleased to offer Ascentis RP-Amide, which has all the benefits of enhanced polar compound retention and selectivity, without any of the disadvantages of competitive EPG phases. Halogenation, in which one or more hydrogen atoms of an amine is replaced by a halogen atom, occurs with chlorine, bromine, and iodine, as well as with some other reagents, notably hypochlorous acid (HClO).
A functional group containing a carbonyl group linked to a nitrogen atom.