androgen insensitivity syndrome symptoms
Androgen insensitivity syndrome is a condition that affects sexual development before birth and during puberty. People with this condition are genetically male, with one X chromosome and one Y chromosome in each cell. Symptoms of Androgen Insensitivity Syndrome: A person with this form of the condition has the external sex characteristics of female but has no uterus and has very little armpit and pubic hair. Such person does not menstruate and are unable to conceive a child (infertile) because he does not have a uterus. Other symptoms of partial androgen insensitivity syndrome include failure of one or both of the testicles to descend into the scrotum after birth and an abnormal penis in which the urethra opens on the underside, instead of at the tip. Check out the treatment and symptoms of Androgen Insensitivity Syndrome, a condition that affects sexual development before birth and during puberty. A group of genetic disorder which affects the growth of both the genital and reproductive organs is commonly known as androgen insensitivity syndrome (AIS). Signs & Symptoms. The symptoms of partial androgen insensitivity syndrome can vary greatly. In the least severe cases, the only symptom that presents itself may be infertility which is related to hardening of the tubules in the testis (seminiferous tubular sclerosis), and either very little or no sperm in the semen. Androgen insensitivity syndrome is a genetic condition which affects a child’s sexual development before birth and during puberty. People with this syndrome are genetically male (they carry both an X and a Y chromosome), but are born with all or some of the physical traits of a female. Androgen insensitivity syndrome (AIS) is caused by various genetic defects on the X chromosome. These genetic defects make the body not capable to respond to the hormones responsible for the male appearance. It is mainly caused by a mutation of the androgen receptor gene which is present in the X-chromosome. Because their bodies are unable to respond to certain male sex hormones (called androgens), they may have some physical traits of a woman. Androgen insensitivity syndrome is caused by mutations in the AR gene and is inherited in an X-linked recessive pattern. Last updated: 1/13/2016. Symptoms of the following disorders can be similar to those of partial androgen insensitivity syndrome. Complete androgen insensitivity syndrome (CAIS) is characterized by a shutdown of the androgen receptor gene. The fetus cannot respond at all to the presence of androgens in the fetal bloodstream. Signs and symptoms. Infants with complete androgen insensitivity syndrome appear to be female at birth, but do not have a uterus, fallopian tubes or ovaries. Their testicles are hidden inside the pelvis or abdomen. Breasts develop during puberty, but there is little or no pubic and armpit hair.
A person with this form of the condition has the external sex characteristics of female but has no uterus and has very little armpit and pubic hair.