are osteoblasts cuboidal
Osteoblast. Osteoblasts are a short-lived cell and the basis for their replenishment is a topic of some interest in understanding how the tissue is organized as a system. From: Osteoporosis (Fourth Edition), 2013. Related terms: Osteoclast; Osteocyte; RANKL; Chondrocyte; Mesenchyme; Calcitriol; MSC (gene) Bone Mass; Stem cells; Stromal cell osteoblasts large, granular cells, can't undergo mitosis, found on surface of bone form bone, secrete the osteoid: collagen, proteoglycans, glycoproteins. Osteoblast are cuboidal mononuclear bone cells 15-30 µm in length, which form a contiguous monolayer over the surface of bone. They are derived from marrow stromal cells by differentiation of pre-osteoblasts and not themselves undergo mitosis. Mature osteoblasts actively engaged in this process are recognized by their location on the bone surface and by their morphologic features typical of cells secreting high levels of proteins: cuboidal shape with large nucleus, enlarged Golgi apparatus, and extensive endoplasmic reticulum. Osteoblasts synthesize the organic component of the bone matrix (osteoid) Osteoid consists of type I collagen, glycosaminoglycans and proteoglycans. When fully active, osteoblasts are cuboidal or polygonal cells. They have basophilic cytoplasm, which reflects the abundance of rough endoplasmic reticulum in their cytoplasm, resulting from their role as active protein-synthesizing and -secreting cells. But the CO2 in his blood rises only slightly before he starts to breathe faster and his heart starts beating stronger. Soon his increased rate of CO2 production is balanced by an increased rate of CO2 removal. This would be an example of _____ feedback because the jogger's circulatory and respiratory systems are _____. Microscopic analysis of an unknown tissue sample reveals the presence of chondrocytes, indicating that the sample was probably taken from _____ tissue. () The matrix of blood tissue, where water, salts, and dissolved proteins are found, is _____. Its absence or dysfunction leads to impaired osteoblast differentiation, premature apoptosis of osteoblasts and osteocytes, and deficient response to hormones and pharmacotherapeutic agents. 32 Furthermore, gap junction communication is fundamental for the maintenance of a continuum from bone, where osteocytes reside, through bone surface cells, osteoblasts and osteoclasts, bone marrow cells, and endothelial cells of the blood vessels. 33 This functional syncytium might be responsible for ... In most animals, food is digested by _____, _____ are absorbed by body cells, and most energy-containing molecules are used to generate _____. () The amount of energy expended while an endothermic organism is resting, unstressed, and not actively digesting or growing is called its _____. Osteoblasts are mononucleate cuboid cells that are responsible for bone formation. Osteoblasts originate from immature mesenchymal stem cells, which can also differentiate and give rise to chondrocytes, muscle, fat, ligament and tendon cells (Aubin and Triffitt, 2002). In actively growing bone, however, for example in fetal bone or in a period of high turnover in adult bone, these cells are much larger and more numerous, containing plump oval nuclei and more abundant spindle-shaped cytoplasm (Fig. 13.16), converting to cuboidal active osteoblasts.
Osteoblast are cuboidal mononuclear bone cells.