alkaline phosphatase level symptoms
More about symptoms of Alkaline phosphatase elevation: Alkaline phosphatase elevation as a symptom: For a more detailed analysis of Alkaline phosphatase elevation as a symptom, including causes, drug side effect causes, and drug interaction causes, please see our Symptom Center information for Alkaline phosphatase elevation. Medical articles and books on symptoms: Phosphoethanolamine and pyridoxal 5'-phosphate are substrates for alkaline phosphatase and are elevated in patients with HPP. Pyridoxal 5'-phosphate is a product of vitamin B-6, and patients taking supplements containing vitamin B-6 should discontinue them two weeks prior to measurement.. However, in the context of the appropriate clinical setting, a low alkaline phosphatase is strong evidence for a diagnosis of HPP.. Dr. Tebben explains: When interpreting the result of an alkaline phosphatase measurement, it is crucial to utilize the appropriate age and gender-specific reference ranges. Hypophosphatasia (HPP) is an inborn error of metabolism with highly variable clinical severity caused by loss-of-function mutations in the gene encoding tissue nonspecific alkaline phosphatase (TNSALP). The prevalence of the severe form is estimated to be between 1/100,000 and 1/300,000. Quick Answer. Because an elevated alkaline phosphatase, or ALP, level can be associated with different medical conditions like rickets, cirrhosis, hepatitis, bone cancer, Paget's disease, hyperparathyroidism and a deficiency in vitamin D, symptoms and treatment options are different and dependent on the specific cause, as noted by WebMD. A: An alkaline phosphatase, or ALP, blood test measures the body's level of ALP, which is a protein existing in all body tissues, explains MedlinePlus. The bo... Full Answer > Filed Under: Medical Ranges & Levels. Alkaline phosphatase is an enzyme that is involved in the production of bone, so it is found at higher levels in children than in adults. The enzyme is primarily produced in mucosal cells that line the bile duct. Low alkaline phosphatase levels are linked to a wide range of conditions. slide 1 of 5. Alkaline Phosphatase Explained Alkaline phosphatase is an enzyme that is associated with the calcification process in developing bones. The role was first suggested as long ago as 1923 by Robison. Alkaline phosphatase is an enzyme in our body. A normal level in adults is 30-140 IU/L. When a blood test shows a level lower than this, it is called hypophosphatasemia. At OneHowTo we will look at causes low alkaline phosphatase. Main symptoms of low alkaline phosphatase. Low alkaline phosphatase can produce symptoms such as fatigue, tachycardia (a pulse of more than 120 beats per minute), shortness of breath, intolerance to cold, constipation or major weight loss. The list of signs and symptoms mentioned in various sources for Alkaline phosphatase elevation includes the 1 symptoms listed below: 1  Increased alkaline phosphatase level. 2  more information...». If there is disease in the liver, bile ducts or gallbladder, alkaline phosphatase is released to the blood stream causing its level to rise. Alkaline phosphatase levels are measured when there are concerns over liver or bone diseases, primarily.
For low alkaline phosphatase, symptoms such as fatigue, tachycardia, shortness of breath, intolerance to cold, constipation or major weight loss.