are benzodiazepines safe for breastfeeding mothers
Hydrocodone has been used frequently in breastfeeding mothers worldwide. Less than 3.7% of the weight-adjusted maternal dose (RID) reaches the infant per day. Higher doses (10 mg of hydrocodone) and/or more frequent administration may lead to neonatal sedation and should be used with great caution. View the original guideline documentation. This is the current release of the guideline. This guideline updates a previous version: Montgomery A, Hale TW, Academy of Breastfeeding Medicine Protocol Committee. ABM clinical protocol #15: analgesia and anesthesia for the breastfeeding mother. Breastfeed Med 2006 Winter;1(4):271-7. *An important concept when discussing the risk of maternal medications to the breastfeeding infant is that of the relative infant dose. It is imperative to understand that this is a value that is calculated by dividing the infant's dose from the milk in mg/kg/day by the mother's dose in mg/kg/day. 1 Benzodiazepines are considered safe in breastfeeding if the dose is less than the equivalent of diazepam 20mg per 24 hours.  Caution is advised in the benzodiazepines with the longest half-life, in premature infants and in long term use. 1 Respiratory depression in neonate may occur if pre delivery dose significant. If mothers use is chronic, withdrawal is also seen.  Benzodiazepines are considered safe in breastfeeding if the dose is less than the equivalent of diazepam 20mg per 24 hours. Alprazolam Levels and Effects while Breastfeeding. Because of reports of effects in infants, including sedation, alprazolam is probably not the best benzodiazepine for repeated use during nursing, especially with a neonate or premature infant. A shorter-acting benzodiazepine without active metabolites is preferred. 1 No known neuro-behavioural teratogenicity. 2  Respiratory depression in neonate may occur if pre delivery dose significant. If mothers use is chronic, withdrawal is also seen.  Benzodiazepines are considered safe in breastfeeding if the dose is less than the equivalent of diazepam 20mg per 24 hours. Alprazolam use while Breastfeeding. Alprazolam Levels and Effects while Breastfeeding. Summary of Use during Lactation. Because of reports of effects in infants, including sedation, alprazolam is probably not the best benzodiazepine for repeated use during nursing, especially with a neonate or premature infant. 1 If mothers use is chronic, withdrawal is also seen. 2  Benzodiazepines are considered safe in breastfeeding if the dose is less than the equivalent of diazepam 20mg per 24 hours.  Caution is advised in the benzodiazepines with the longest half-life, in premature infants and in long term use. Use in Lactation. 1  Benzodiazepines are considered safe in breastfeeding if the dose is less than the equivalent of diazepam 20mg per 24 hours.  Caution is advised in the benzodiazepines with the longest half-life, in premature infants and in long term use.
Yes, Benzodiazepines are considered safe in breastfeeding if the dose is less than the equivalent of diazepam 20mg per 24 hours.