antigen detection for dengue meaning
The detection of secretory NS1 protein represents a new approach to the diagnosis of acute DV infection. In this study, an attempt has been made to evaluate the NS1 Ag assay as a new diagnostic tool for early diagnosis of dengue virus infection in a tertiary care hospital. Interpretation Provides information to assist in interpretation of the test results. The presence of dengue nonstructural protein 1 (NS1) antigen is consistent with acute-phase infection with dengue virus. The NS1 antigen is typically detectable within 1 to 2 days following infection and up to 9 days following symptom onset. How to cite this URL: Datta S, Wattal C. Dengue NS1 antigen detection: A useful tool in early diagnosis of dengue virus infection. Indian J Med Microbiol [serial online] 2010 [cited 2017 Apr 15];28:107-10. An aid in the diagnosis of dengue virus infection. Dengue virus (DV) is a globally distributed flavivirus with 4 distinct serotypes (DV-1, -2, -3, -4) and is primarily transmitted by the Aedes aegypti mosquito, found throughout the tropical and subtropical regions of over 100 countries. The results reveal the detection rate of dengue virus infection. was similar for PCR and dengue antibody (65.9%) and for NS1 antigen and den-. gue antibody (62.0%) combinations. Therefore, the dengue NS1 antigen test can. be used to complement the current antibody test used in peripheral laboratories. Thus, the combination of the NS1 antigen and antibody tests could increase the. diagnostic efficiency for early diagnosis of dengue infection. For other uses, see Dengue fever (disambiguation). Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Symptoms typically begin three to fourteen days after infection. This may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash. Recovery generally takes two to seven days. NS1 antigen test. NS1 antigen test ( nonstructural protein 1), is a test for dengue, introduced in 2006. It allows rapid detection on the first day of fever, before antibodies appear some 5 or more days later. It has been adopted for use in some 40 nations. The method of detection is through enzyme-linked immunosorbent assay. Purpose: This study was undertaken to evaluate the efficacy of NS1 antigen (Ag) assay as an early marker for dengue virus (DV) infection. Materials and Methods: Group I evaluated the performance of NS1 antigen (Ag) assay in comparison to MAC-ELISA and their detection rate when performed together in a single sample. Dengue is an arthropod-borne flavivirus that comprises four distinct serotypes (DEN-1, DEN-2, DEN-3 and DEN-4) that constitute an antigenic complex of the genus flavivirus, family Flaviviridae. Accurate and timely diagnosis of dengue virus is important for early. detection of dengue virus infection. In this study, the usefulness of the dengue. NS1 antigen test was evaluated as a routine, rapid diagnostic test for dengue vi-. rus infection. A total of 208 sera from patients suspected of having dengue virus.
A test for dengue, introduced in 2006.