acinar cell
Acinar cell carcinoma. An adenocarcinoma arising from secreting cells of a racemose gland, particularly the salivary glands. Racemose gland: A gland that has the appearance of a bunch of grapes if viewed as a three-dimensional reconstruction; e.g., a compound acinous or alveolar gland. Acinar Cells (PaA) Acinar cells of the pancreas produce and secrete digestive enzymes, which are secreted to the intestine by a branched ductal network. The bulk of the mature pancreas is comprised of acinar cells. Acinar cells are also involved in pathological processes and are the initiating cell type for precursor lesions of pancreatic cancer. Acinar cells. 1  Acinar cells are the exocrine (exo=outward) cells of the pancreas that produce and transport enzymes that are passed into the duodenum where they assist in the digestion of food. Spindle cells (focal) Recognized as acinar based on architectural pattern, nuclear features and presence of classical acinar appearance in other areas. Mixed differentiation may occur Each component must comprise at least 25% of the tumor. Behavior for mixed neoplasms is similar to pure acinar cell carcinoma. Mixed acinar-endocrine requires immunohistochemistry for recognition. Mixed acinar-ductal or mixtures of all three may occur. Final Diagnosis -- Acinar cell carcinoma of the pancreas. Acinar cell carcinoma of the pancreas is a rare neoplasm, comprising 1-2 % of exocrine pancreatic tumors (Solcia E et al., 1997). The tumor most commonly occurs in middle-aged or elderly Caucasian men. Patients may present with vague abdominal pain, or the mass may be found incidentally. Pancreatic Acinar Cell Cancer. Acinar cell neoplasms arise from the acinar cells of the pancreas. Normal acinar cells are the primary cells of the exocrine pancreas and are responsible for secreting various enzymes. These tumors are distinct from the more common adenocarcinomas of the pancreatic ducts. Acinar cell carcinoma. Acinar cell carcinoma. Description, Causes and Risk Factors: An adenocarcinoma arising from secreting cells of a racemose gland, particularly the salivary glands. Racemose gland: A gland that has the appearance of a bunch of grapes if viewed as a three-dimensional reconstruction; e.g., a compound acinous or alveolar gland. Carcinoma of the pancreas exhibiting exocrine differentiation and lacking significant (<25%) ductal or endocrine differentiation. Acinic cell carcinoma. (Note that solid-pseudopapillary neoplasm was erroneously considered in some early reports to be acinar and designated cystic acinar cell carcinoma) Acinar cells. Acinar cells are the exocrine (exo=outward) cells of the pancreas that produce and transport enzymes that are passed into the duodenum where they assist in the digestion of food. Islets of Langerhans. The prognosis of Acinar Cell Carcinoma of Pancreas depends upon many factors including the stage of the tumor and overall health of the individual. The survival rate of individuals with Pancreatic Cancer, Acinar Type is typically poor.
Acinar cells are the exocrine (exo=outward) cells of the pancreas that produce and transport enzymes that are passed into the duodenum where they assist in the digestion of food.