absolute neutropenia definition
Neutropenia can be acute (temporary) or chronic (long lasting). The term is sometimes used interchangeably with leukopenia (deficit in the number of white blood cells). Neutropenia is a condition in which the number of neutrophils (a type of white blood cell) in the bloodstream is decreased, affecting the body's ability to fight off infections. Neutropenia is defined as an absolute neutrophil count (ANC) of less than 1500 per microliter (1500/microL) Specific causes include: 1  Kostmann's syndrome — a congenital disorder involving low production of neutrophils. 2  Myelokathexis — a congenital disorder involving failure of neutrophils to enter the bloodstream. 3  Leukemia. Myelodysplastic syndromes. 4  Myelofibrosis. Chemotherapy.  Alcohol use 1  disorder. Chronic idiopathic neutropenia in  adults. Neutropenia or neutropaenia, is an abnormally low concentration of neutrophils (a type of white blood cell) in the blood. Neutrophils make up the majority of circulating white blood cells and serve as the primary defense against infections by destroying bacteria, bacterial fragments and immunoglobulin-bound viruses in the blood. Conditions that destroy neutrophils in the bloodstream and that can result in neutropenia include: 1  Rheumatoid arthritis and other autoimmune disorders. 2  Medications, such as antibiotics. 3  Hypersplenism — an abnormality of the spleen causing blood cell destruction. absolute neutrophil count (ANC) the number of neutrophils in a milliliter of blood, having a reference value of approximately 1500-7700 per μL. The ANC is a measure of a person's immune status. absolute neutrophil count. The actual number of neutrophils in a cubic millimeter of blood. The approximate normal range is 3000 to 6000 cells/mm3. This figure is measured before and after drugs are given that may lower neutrophil counts, such as those used in cancer chemotherapy. Greater decline in absolute neutrophil count (ANC), a measure of the number of neutrophils present in the blood, correlated with worse QoL at ANC nadir (lowest point) for measures of Role Physical, Social Functioning, General Physical Symptoms and Distress. Absolute neutrophil count. Absolute neutrophil count (ANC) is a measure of the number of neutrophil granulocytes (also known as polymorphonuclear cells, PMN's, polys, granulocytes, segmented neutrophils or segs) present in the blood. Neutrophils are a type of white blood cell that fights against infection. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations.
Neutropenia is a condition in which the number of neutrophils in the bloodstream is decreased, affecting the body's ability to fight off infections.