______ is a group of rare diseases that cause abnormal growth of the body's connective tissue.
There are other less common causes of gigantism: McCune-Albright syndrome causes abnormal growth in bone tissue, patches of light-brown skin, and gland abnormalities. Carney complex is an inherited condition that causes non-cancerous tumors on connective tissue, cancerous or non-cancerous endocrine tumors, and spots of darker skin. Multiple endocrine neoplasia type 1 (MEN1) is an inherited disorder that causes tumors in the pituitary gland, pancreas, or parathyroid glands. Gigantism is a rare condition that causes abnormal growth in children. It occurs when your child’s body produces far too much growth hormone. Gigantism is a rare condition that causes abnormal growth in children. Mixed Connective Tissue Disease (MCTD) Pediatric mixed connective tissue disease (MCTD) is a rare disease in children that has symptoms of arthritis along with features of scleroderma, dermatomyositis and lupus. It is characterized by lab tests showing the presence of specific antibodies to nuclear proteins (specifically, RNP). MCTD is a type of autoimmune disease. Myositis may occur on its own or in conjunction with other connective tissue diseases. Osteoarthritis. Osteoarthritis is the most common type of arthritis, especially among older people. In fact, more than half of the population age 65 or older has X-ray evidence of osteoarthritis in at least one joint. Both men and women have the disease. Raynaud’s Disease. Raynaud's disease is a condition that causes some areas of your body – such as your fingers, toes, tip of your nose and your ears – to feel numb and cool in response to cold temperatures or stress. It's a disorder of the blood vessels that supply blood to your skin. Though it is often referred to as if it were a single disease, scleroderma is really a symptom of a group of diseases that involve the abnormal growth of connective tissue, which supports the skin and internal organs. In some forms of scleroderma, hard, tight skin is the extent of this abnormal process. In this theory, the body has an abnormal response to a viral infection. The immune system attacks and clears the virus, but it does not stop the attacking process. Instead, it begins to attack the body's own tissue(s). There is evidence that some people are more likely to have this type of abnormal immune response. UConn Musculoskeletal Institute. Rheumatology. The Rheumatology Center in the UConn Musculoskeletal Institute at UConn Health has nationally recognized experts in the diagnosis and treatment of connective tissue disorders like rheumatoid arthritis, lupus, scleroderma, Sjogren’s syndrome and anti-phospholipid syndrome. It is a relatively under diagnosed disease. At the UConn Musculoskeletal Institute we have a large group of Sjögren’s syndrome patients and are one of the larger centers for this condition. Antiphospholipid Syndrome. This is a condition that can occur by itself or in conjunction with lupus or other connective tissue diseases. The affected patients are prone to blood clots and pregnancy losses. Over the years we at the Rheumatology Center have successfully managed women with this condition who are at risk for a miscarriage and seen them through their pregnancy to a successful outcome. Early diagnosis is important. Prompt treatment can stop or slow the changes that may cause your child to grow larger than normal. However, the condition can be hard for parents to detect. The symptoms of gigantism might seem like normal childhood growth spurts at first.
Mixed Connective Tissue Disease or Pediatric mixed connective tissue disease is a rare disease in children, that cause abnormal growth of the body's connective tissue.