are decongestants nsaids
Decongestants may be taken by mouth or applied directly on the nasal mucus membrane in the form of nose drops and sprays. (31). Decongestant nose drops and sprays have rapid and powerful action in relieving nasal obstruction. (31) When the decongestant effect of the drug wears off, nasal obstruction rapidly returns. One of skill in the art would know of many other appropriate decongestants and their approved dosages. [0033] The exemplified decongestant is pseudoephedrine. The usual adult dose of pseudoephedrine is 60 mg every 4-6 hours, up to a maximum of 240 mg per day. [0023] It has been discovered that the addition of a non-steroidal anti-inflammatory agent to a composition containing an antihistamine and/or a decongestant enchances the efficacy of the antihistamine and decongestant, thus permitting a reduction in the total dose of either or both. Common cold medications. by Ashlee Davis. When you have a cold, it can be hard to sort through the dizzying array of over-the-counter cold medications. But many cold medications contain just a few types of drugs. The key is to check the list of ingredients and match the right drug to your symptoms. Decongestants. Decongestants, such as pseudoephedrine, are in the category of alpha-adrenergic agonists. (31) These drugs open the nasal passages by shrinking blood vessels in the mucus membrane of the nose, which is the primary cause of the nasal obstruction of colds. Nonsteroidal antiinflammatory drugs, such as ibuprofen and naproxen, are effective in treating inflammation, pain, and fever. (25) A major action of NSAIDs is to block the production of certain natural inflammatory mediators called prostaglandins.. How to Pick an Over-the-Counter Cold Remedy. When you have a cold, it can be hard to sort through the dizzying array of over-the-counter cold medications. NSAIDs have been used in medical practice to treat general symptoms of a cold such as feverishness, chilliness, muscle ache, and not feeling well in general. (25) Also there has been interest in the use of NSAIDs to treat other cold symptoms, especially cough. In particular, the amount of antihistamine and/or the decongestant can be less or equal to about 75% of an amount present in an approved dose of the decongestant or the antihistamine relative to an amount of the NSAID corresponding to about 100% of the amount present in a normal strength dosage form of the NSAID. Patents. The present invention is directed to a pharmaceutical composition and method for the treatment of rhinitis and cold-like symptoms which includes a non-steroidal anti-inflammatory drug (NSAID), a decongestant, and an antihistamine. It has been found that an NSAID enhances the activity of a decongestant...
Yes