are bupropion manufacturers different
Four other manufacturers make bupropion XL in 300 mg tablets, and patients can still get their prescription filled with these products. The other four generic versions of 300 mg extended-release bupropion tablets are not affected by FDA's recent announcement, said FDA spokesperson Sandy Walsh.our other manufacturers make bupropion XL in 300 mg tablets, and patients can still get their prescription filled with these products. The other four generic versions of 300 mg extended-release bupropion tablets are not affected by FDA's recent announcement, said FDA spokesperson Sandy Walsh. The FDA said it believes the problem is limited to Budeprion XL 300 mg, but it has requested that four other manufacturers, Actavis, Anchen, Mylan, and Watson, which make their own 300 mg generic bupropion tablets, conduct studies to show their pills are equivalent to Wellbutrin XL 300 mg.he FDA's action is based on a study it conducted in 24 adults that found generic Budeprion XL 300 mg is not released into the bloodstream at the same rate and in the same amount as branded Wellbutrin XL 300 mg. Bupropion is the generic or chemical name of the drug and Budeprion and Wellbutrin are brand names. Drugs can have both a generic name and a brand name. The FDA released a statement that the brand named medication; Budeprion XL 300 mg is not therapeutically equivalent to the brand named medication Wellbutrin XL 300 mg.This means that these two versions of bupropion XL 300 mg do not work the same when given to patients.he FDA does studies to make sure that all the different brands and generic formulations are the same. The FDA did the studies on the dose of bupropion XL 150 mg and concluded that all the manufacturers were making equivalent medications. Previous research to gain the generic approval from the FDA showed the Budeprion XL 150 mg pill is equivalent to Wellbutrin XL 150 mg. Bottom line: If you take generic bupropion 300 mg, check your prescription pill bottle.If it contains the brand name Budeprion XL or it lists either Impax or Teva as the manufacturer, contact your doctor or pharmacist for an alternative.he FDA's action is based on a study it conducted in 24 adults that found generic Budeprion XL 300 mg is not released into the bloodstream at the same rate and in the same amount as branded Wellbutrin XL 300 mg. FDA has determined that this approach is no longer appropriate to establish bioequivalence of 300 mg bupropion hydrochloride extended-release tablets to Wellbutrin XL 300 mg, and the Agency is revising its guidance to industry for how to conduct premarket bioequivalence studies in generic bupropion products.e have completed our review of the studies from all four manufacturers of bupropion HCl ER 300 mg products currently on the market: Actavis, Inc.,* Mylan Inc., Par Pharmaceutical (formerly Anchen Pharmaceuticals), and Watson.*. FDA has approved five generic versions of Wellbutrin XL 300 mg. Each of these generics was approved based on bioequivalence studies comparing the 150 mg strength of the products to Wellbutrin XL 150 mg. Studies were not performed directly on the 300 mg strength of the products.e have completed our review of the studies from all four manufacturers of bupropion HCl ER 300 mg products currently on the market: Actavis, Inc.,* Mylan Inc., Par Pharmaceutical (formerly Anchen Pharmaceuticals), and Watson.*. The other four generic versions of 300 mg extended-release bupropion tablets (manufactured by Anchen, Actavis, Watson, and Mylan) are not affected by today’s announcement. FDA does not currently have data indicating that these products are not bioequivalent to Wellbutrin XL 300 mg.he product that Teva markets as Budeprion XL 300 mg (extended-release bupropion hydrochloride 300 mg) is manufactured by Impax Laboratories, Inc. The approved abbreviated new drug application (ANDA) number for this product is 077415 and the application is held by Impax. What we found will shock you. A once-a-day (XL) generic bupropion XL released its ingredient at a very different rate than Wellbutrin XL. Differences in how products dissolve may explain the side-effects and return of depression reported by some patients switched to a generic.And two twice-a-day (SR) generics also differed from one another. Which products behaved like the original Wellbutrin in our tests and which did not. 2  What these differences can mean to you. 3  A list of generic bupropion products by distributor and manufacturer to help you tell them apart, including versions from Par (previously Anchen) and Sandoz. Many patients also reported a loss of antidepressive effect. Patients who thereafter switched back to Wellbutrin XL or an alternative generic (such as Bupropion XL manufactured by Watson Pharmaceuticals) saw a return of the antidepressive effect and lessening of side effects. have taken prescription Bupropion XL (Generic for Wellbutrin XL) for many years. Frequently the pharmacy will refill using a generic of their choice. There is only one version of bupropion xl that has worked for me. The FDA's action is based on a study it conducted in 24 adults that found generic Budeprion XL 300 mg is not released into the bloodstream at the same rate and in the same amount as branded Wellbutrin XL 300 mg.he FDA's action is based on a study it conducted in 24 adults that found generic Budeprion XL 300 mg is not released into the bloodstream at the same rate and in the same amount as branded Wellbutrin XL 300 mg.
Yes