are nsaids harmful to the heart
When combined with blood-thinning medicines (such as warfarin) NSAIDs increase the risk of bleeding. NSAIDs can cause kidney failure when they are combined with ACE inhibitors (medicines used to treat heart problems and high blood pressure) and diuretics (medicines to remove excess fluid). For example: 1  When combined with blood-thinning medicines (such as warfarin) NSAIDs increase the risk of bleeding. 2  NSAIDs can cause kidney failure when they are combined with ACE inhibitors (medicines used to treat heart problems and high blood pressure) and diuretics (medicines to remove excess fluid). Nonsteroidal anti-inflammatory drugs (NSAIDs) ­– traditional ones such as ibuprofen (Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), and the COX-2 selective inhibitor celecoxib (Celebrex) – are widely used to treat arthritis because they help relieve pain and reduce inflammation. In the meantime, we continue to believe that celecoxib should be used as a last resort, and only by people who are at low risk of heart disease or stroke, high risk of gastrointestinal problems, or who have not responded to less risky alternatives. People who don't get adequate relief from acetaminophen or can't take it for health reasons: Generic ibuprofen or naproxen. Those drugs are cheaper than other NSAIDs, and less likely than aspirin to harm the stomach. People at high risk of heart attack: Naproxen. NSAIDs are also used to treat non-inflammatory conditions such as migraine, period pain and postoperative pain, and to reduce fever. Aspirin is an NSAID with ‘blood-thinning’ properties. It can be used in low doses to reduce the risk of heart attack and stroke in high-risk patients. Since 2001, several studies – including one from 2011 in BMJ and a 2013 review in The Lancet – have linked long-term, high-dose NSAID use to a greater risk for heart attack, stroke, heart failure and death from cardiovascular disease. Even Naproxen Risky at High Dose. Our results suggest that all NSAIDs have harmful effects in heart-failure patients, even naproxen at high doses. Naproxen is probably the best of the bunch, but it still increases fluid retention, which is bad news for heart-failure patients, Gislason added. If you’re at high risk for heart disease due to high blood pressure or high cholesterol and your doctor thinks you need NSAIDs, it’s important to control your existing risks, Dr. Abramson advises. Diet, exercise, and weight loss can both protect your heart and take weight off your joints, improving your arthritis. Nearly a decade after reports first surfaced linking the prescription pain reliever celecoxib (Celebrex) to an increased risk of heart attack, and two years after the American Heart Association (AHA) warned against the drug for people at risk of heart problems, about 11 million prescriptions for it are still filled each year, often for arthritis, ...
No, if used as a low doses.