american heart association what is bnp mean
Since its discovery over 15 years ago, brain natriuretic peptide (BNP), also referred to as B-type natriuretic peptide, has emerged as an important biomarker with an established role in the diagnosis of congestive heart failure (CHF). BNP is a substance secreted from the ventricles or lower chambers of the heart in response to changes in pressure that occur when heart failure develops and worsens. The level of BNP in the blood increases when heart failure symptoms worsen, and decreases when the heart failure condition is stable. American Heart Association. The American Heart Association is a non-profit organization in the United States that fosters appropriate cardiac care in an effort to reduce disability and deaths caused by cardiovascular disease and stroke. It is headquartered in Dallas, Texas. Freebase(0.00 / 0 votes)Rate this definition: The American Heart Association is a non-profit organization in the United States that fosters appropriate cardiac care in an effort to reduce disability and deaths caused by cardiovascular disease and stroke. We're still learning what the BNP means in HCM. Typically, the BNP will be higher just because the heart muscle walls are more stiff and less compliant than the normal heart. As we learn more, we'll be able to determine the best use of the study for the typical HCM patient. The primary value of BNP and NT-proBNP testing in the ED is its diagnostic value in the differential diagnosis of acute dyspnea and possible CHF. levels of the natriuretic peptides may also assist the emergency physician in appropriately triaging the patient with CHF. Normal Activity of Natriuretic Peptides. Brain natriuretic peptide (BNP) is a member of a family of 4 human natriuretic peptides that share a common 17-peptide ring structure.The first was identified in 1983 and named atrial natriuretic peptide (ANP). ANP is a 28-amino acid polypeptide resulting from the C-terminal end of the prohormone proANP. Heart failure is a condition in which the heart can't pump enough blood to meet the body's needs. Heart failure does not mean that your heart has stopped or is about to stop working. It means that your heart is not able to pump blood the way it should. It can affect one or both sides of the heart. The weakening of the heart's pumping ability causes. Blood and fluid to back up into the lungs. The utility of brain natriuretic peptide (BNP) testing in the acute care setting is derived from the landmark Breathing Not Properly study and later studies.The initial Breathing Not Properly multicenter prospective study involved 1586 patients presenting to the emergency department (ED) with acute dyspnea. The BNP level in a person with heart failure - even someone whose condition is stable - is higher than in a person with normal heart function. To test the BNP level, a small amount of blood is taken and placed in a machine that detects the level of BNP in your blood. The test takes about 15 minutes. The BNP level helps to determine if you have heart failure, rather than another condition that may cause similar symptoms.
A substance secreted from the ventricles or lower chambers of the heart in response to changes in pressure that occur when heart failure develops and worsens.