HRSA’s Response to HIV Treatment Advances

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Hope was replaced by elation in July 1996, at the XI International Conference on AIDS, when David Ho announced that HIV could be eradicated if it was completely suppressed for 2 or 3 years. At the same time, several reports suggested that HIV could be fully suppressed by combining two NRTIs with either an NNRTI or a PI. The HAART era had begun. “We had turned directions really quickly. It was like a light switch, going from terrible pessimism to exaggerated optimism in less than a year,” says Cheever.

17. Centers for Disease Control and Prevention. Recommendations of the U.S. Public Health Service Task Force on the Use of Zidovudine to Reduce Perinatal Transmission of Human Immunodeficiency Virus. MMWR. 1994;43:1-20. Available at: www.cdc.gov/mmwr/preview/mmwrhtml/00032271.htm. Accessed August 8, 2011.

18. Centers for Disease Control and Prevention. US Public Health Service recommendations for human immunodeficiency virus counseling and voluntary testing for pregnant women. MMWR. 1995;44.

39. National Alliance of State and Territorial AIDS Directors. The fiscal status of state AIDS Drug Assistance Programs: findings from a January 1996 national survey of state AIDS directors. April 1996.

67. Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services. December 1, 2009. Available here (PDF – 1.5 MB). Accessed August 19, 2011.

69. Centers for Disease Control and Prevention. Report of the NIH Panel to Define Principles of Therapy of HIV Infection and Guidelines for the Use of Antiretroviral Agents in HIV-Infected Adults and Adolescents. MMWR. 1998;47. Available here. Accessed August 14, 2011.

110. Based on information at the FDA Web site Timeline/history, available here. Accessed August 1, 2011.

111. Source: Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services. December 1, 2007. Available here (PDF – 2.3 MB). Accessed August 24, 2011.