Q:

How does the de Broglie-Bohm picture explain the double-slit experiment with single particles?

If the particle has a single well-defined trajectory in the de Broglie-Bohm theory, how come that the interference pattern still appears even with single particles?

A:

To elucidate Luc's answer somewhat, the Bohmian wave function still travels through both slits and causes an interference pattern, it's just the beables (particles) being guided by this wave that only travel through one slit. Because they're being guided by a wave that's exhibiting interference, the particle positions on the screen reflect this interference pattern.
There's a good animation of this here that might clear things up somewhat, or in image form:

(found at this link from a Google image search; although this particular illustration I believe is by David Bohm originally)
It's apparent from this, and interesting to note, that Bohmian trajectories don't cross. It's therefore possible to a priori determine which slit each particle passed through from its position on the screen. Measurement of a particle in transit affects its momentum however, so we still can't observe them taking one of these paths. Because of this, whilst this may be a good visual aid for some, it doesn't help over standard quantum mechanics beyond that. Outside the scope of your question, but you may be interested to know that there are other applications where calculating such trajectories are useful though as they can allow for more efficient quantum simulations - this is seen particularly in quantum chemistry.
If anything's not clear or you have any follow-ups, please feel free to ask.

