Meesmann corneal dystrophy

Meesmann corneal dystrophy is a type of corneal dystrophy and a keratin disease.

It is named for German ophthalmologist Alois Meesmann (1888-1969).

It is sometimes called "Meesmann-Wilke syndrome", after the joint contribution of Meesmann and Wilke.

Presentation 
This slowly progressive disorder is characterized by small cysts in the epithelium of the cornea. Patients with Meesmann corneal dystrophy are intolerant of contact lenses, as these devices directly traumatize the corneal epithelium.

Genetics 
It has been associated with genes KRT3 and KRT12 located on chromosome 12 and 17 respectively.

Diagnosis

See also 
 Corneal dystrophy
 List of cutaneous conditions caused by mutations in keratins

References

External links

Category:Disorders of sclera and cornea