Z80 Assembly is an assembly language for the Zilog Z80 processor, which was introduced in 1976 and used in 1980s home computers such as the Sinclair ZX Spectrum and the Amstrad CPC series. In the late 1990s, some TI graphing calculators (e.g. the TI-83 series) were also Z80-based.

The Z80 is binary compatible with the earlier Intel 8080, but the assembly code is different because instead of having several different commands for loading and storing data, there is only one,LD, on the Z80. Therefore, on the assembly level, Z80 code is actually closer to 8086 code when MOV is changed to LD and the different register structure is taken into account.[1]

Today, the Z80 is still widely used in embedded systems and consumer electronics. Several cross assemblers exist for the Z80, e.g. z80asm. Also, some emulators of e.g. the Amstrad CPC feature a built-in assembler.