Coats and vesicle budding.
Transport vesicles need coat proteins in order to form. The coat proteins are recruited from the cytosol onto a particular membrane, where they drive vesicle budding and select the vesicle cargo. So far, three types of coated transport vesicles have been purified and characterized, and candidates for components of other types of coats have been identified. This review gives a brief overview of what is known about the various coats and their role in transport vesicle formation.