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Introduction

The sudden appearance of a rash, which is a common presentation in children (see CHAPTER 93), usually provokes patients and doctors alike to consider an infectious aetiology, commonly of viral origin. However, an important cause to consider is a reaction to a drug.

A knowledge of the relative distribution of the various causes of rashes helps with the diagnostic methodology. Many of the eruptions are relatively benign and undergo spontaneous remission. Fortunately, the potentially deadly rash of smallpox is no longer encountered.