Infection of the small intestine by type A strains of C perfringens is a milder condition and rarer than disease caused by C perfringens type C (see Clostridium perfringens Type C Enteritis in Pigs). Suckling and sometimes weaned pigs are affected and exhibit yellow-colored feces with mucous and flecks of blood. Growth rates are suppressed but with low to no mortality. The lesions at necropsy are milder and blood-free as compared with those of C perfringens type C enteritis. Diagnosis, treatment, and control are as for C perfringens type C enteritis.

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