Immunoglobulin E (IgE) is a class of antibody (or immunoglobulin "isotype") that has been found only in mammals. IgE is a monomeric antibody with 4 Ig-like domains. It plays an important role in allergy, and is especially associated with type 1 hypersensitivity.

Immunogen

Human IgE antibody was raised in mouse using human IgE as the immunogen.