Hageluken and colleagues demonstrated that β-adrenergic antagonists activated G-proteins in isolated cell membranes and it was suggested that this was the mechanism of central analgesia.
Hageluken et al. demostraron que los antagonistas ß-adrenérgicos activaron las proteínas G en membranas de células aisladas y mostraron que ese era el mecanismo de la analgesia central.
Hageluken et al. demonstraram que os antagonistas β-adrenérgicos ativaram as proteínas G em membranas de células isoladas e sugeriram que esse era o mecanismo da analgesia central.