The AMPK phosphorilates and inhibits the acetyl-CoA-carboxylase and, consequently, reduces the concentrations of malonyl-CoA, an allosteric inhibitor of carnitine palmitoyltransferase 1 CPT1.
La AMP-quinasa fosforila e inhibe la acetil-CoA-caboxilasa, y por consiguiente, reduce la concentración de malonil-CoA, inhibidor alostérico de la carnitina palmitoil transferasa CPT-1.
A AMP-quinase fosforila e inibe a acetil-CoA-carboxilase e, consequentemente, reduz a concentração de malonil-CoA, inibidor alostérico da carnitina palmitoil transferase CPT-1.