However, it was only in 1990, after a small cross-sectional study by Tayek et al, that the first evidence of the deleterious cardiovascular effects of this type of treatment were disclosed.
Mientras tanto, solamente en 1990, a partir de un pequeño estudio transversal de Tayek et al, surgieron las primeras evidencias de los efectos deletéreos cardiovasculares de ese tipo de tratamiento.
No entanto, somente em 1990, a partir de um pequeno estudo transversal de Tayek e cols., surgiram as primeiras evidências dos efeitos deletérios cardiovasculares desse tipo de tratamento.