Regarding the methodological quality of the five RCTs, two were single-blinded, three were double-blinded, and only one was multi-centered.
Respecto a la calidad metodológica de los cinco ECAs, dos fueron simple ciego, tres fueron doble ciego, y solo uno fue multicéntrico.
No que diz respeito à qualidade metodológica desses cinco ECR, dois são simples cegos-, três são duplo cegos,-, sendo apenas um multicêntrico.