Regarding the distribution according to the study design, 15 were prospective observational studies 88.23% and two were retrospective observational studies 11.76%, of which five were focused on pediatric patients 29.41% and the remaining 12 ones were focused on adults 70.59%, as described in Table 3.
La distribución según los diseños de estudio, 15 eran observacionales prospectivos 88,23% y dos retrospectivos 11,76%, de los cuales 5 estaban enfocados a pacientes pediátricos 29,41% y los 12 restantes a adultos 70,59%, descritos en la Tabla 3.
Quanto à distribuição de acordo com os delineamentos do estudo, 15 eram observacionais prospectivos 88,23% e dois retrospectivos 11,76%, dos quais cinco eram focados em pacientes pediátricos 29,41% e os 12 restantes em adultos 70,59%, conforme descrito na Tabela 3.