Causative agents of vCJD are prions, composed of misfolded prion proteins (PrPSc), which form aggregates in neurological tissue leading to progressive brain damage and characteristic signs and symptoms of the disease.
Povzročitelji so prioni, ki so sestavljeni iz napačno zvitih prionskih beljakovin, ki oblikujejo agregate v nevrološkem tkivu ter povzročajo progresivne poškodbe možganov in značilne znake in simptome te bolezni.