Patients with vCJD have prominent psychiatric (frequently depression, anxiety and withdrawal) or sensory symptoms and delayed onset of neurologic abnormalities, including ataxia within weeks or months, and dementia and myoclonus late in the illness.
Bolniki z variantno Creutzfeldt-Jakobovo bolezen imajo izrazite psihiatrične (pogosto depresija, anksioznost in umik) ali senzorične simptome in odložen nastop nevroloških nepravilnosti, vključno z ataksijo, ki se pojavi v nekaj tednih ali mesecih, ter demenco in mioklonusom v kasnejši fazi bolezni.