The disease presentation is different from traditional LGV in that the patients have symptoms of inflammation in the rectum (proctitis) and colon (haemorrhagic colitis), and often do not have urethritis or the swollen lymph nodes in the groins that are otherwise typical of LGV.
Bolezen se kaže drugače od običajnega veneričnega limfogranuloma, saj se pojavljajo simptomi vnetja danke (proktitis) in debelega črevesja (hemoragični kolitis), pogosto pa bolniki nimajo uretritisa ali otečenih bezgavk v dimljah, kar je sicer značilno za venerični limfogranulom.