A 47-year-old Caucasian male affected by schizoaffective disorder and mild intellectual disability developed persistent leukocytosis lasting over a 6-year period under treatment with clozapine and lithium. His medical history was otherwise unremarkable.
A 57-year-old Caucasian female with a diagnosis of SCZ and mild intellectual disability presented frequent fluctuations in the leukocyte counts, with values ranging from normal to moderately elevated. Her past medical history was significant for a diagnosis of epilepsy. Along with clozapine, her pharmacotherapy comprised gabapentin, fenobarbital, biperidene, risperidone and clonazepam.