A 68-year-old male complained of superficial but nodular swelling in the right parotid region. The patient complained of pain in ear and the swelling. The swelling measured 3 cm in diameter with restricted mobility and showed erythematous skin over it. The examination of ear, nose and throat was reported to be normal. The patient was advised to be assessed by USG-guided FNAC. The aspirate revealed dissociated to polygonal cells carrying centrally placed hyperchromatic nuclei with rounds prominent nucleoli. Few of the cells showed bi-nucleation. The cytoplasm of these cells carried granules of altered hue. The background showed infrequent melanin containing macrophages []. Cytodiagnosis of melanoma was made with advice to search for primary of melanoma. The re-examination showed 1 cm size of brown-colored tumorous lesion uncomplained by the patient. This primary lesion of the scalp underwent FNAC followed by excision revealing similar diagnosis of melanoma on both occasions.
A 65-year-old male patient sort medical advice for complains of hematuria, lump in abdomen and shortness of breath along with a nodular swelling in the right parotid. The patient was provisionally diagnosed of lump in the abdomen probably malignant arising from right kidney. Meanwhile, his workup for other complains was being carried out, nodule in the right parotid underwent FNAC. It revealed the tubular structures of cuboidal epithelial cells in isolation or within the sheets of cells. The cells carry low-grade malignant nuclei but revealed vacuolated clear appearing cytoplasm with little granularity in a few. Background of smear shows fine vesicles of lipids with few loops of endothelial cells due to consideration to his clinical presentation, a diagnosis highly suspicious of metastases of clear cell RCC was offered []. The patient underwent multiple investigations. FNAC from the sites of renal mass and suspected metastatic nodule of the left lung revealed the cytomorphology consistent with RCC and metastases of RCC in the lung, respectively.\nSuperficial parotidectomy was performed in one case of melanoma. The other cases (n = 2) of metastatic ductal carcinoma breast underwent excision of the nodule within the parotid. The cases diagnosed with metastases of small cell carcinoma and RCC underwent medicinal management (chemotherapy). All five cases showed complete concordance between cyto-histological diagnoses.