A 56-year-old woman began to suffer from an occipital headache for 7 days before admission to our hospital, and dizziness appeared 5 days later. On admission, she complained of dizziness and a mild occipital headache. She showed nystagmus and the right nose-finger-nose test was positive. In peripheral blood cell counts and biochemical studies, elevations in white blood cells (9,200/μl) and low-density lipoprotein cholesterol (215 mg/dl) were observed. Coagulation studies and immunological studies were normal. Head computed tomography (CT) showed low-density areas in the right cerebellar hemisphere, diffusion weighted imaging (DWI) of magnetic resonance imaging (MRI) displayed high-intensity signal areas in the cerebellar vermis and the right cerebellar hemisphere (Fig. ). In addition, a high-intensity signal area was observed just adjacent to the right VA on T1-VISTA (Fig. ), whereas no such high intensity was detected on conventional T1 image. Conventional MRA did not depict the right PICA or any abnormal findings of the right VA (Fig. ). Echocardiography and 24-hour electrocardiography showed no findings suggestive of cardioembolic causes. According to these findings, ischemic stroke of the cerebellum induced by the right PICA-D was diagnosed, and after confirming that she had neither hypertension nor aneurysmal formation, combined therapy with clopidogrel and unfractionated heparin administration was started. T1-VISTA showed a slight expansion of the high-intensity area at 3 days after admission, but still no lesions on T1 images. At 9 days after admission, cerebral angiography revealed the “pearl and string sign” at the proximal portion of the right PICA (Fig. ). At 12 days after admission, the patient was discharged with single antiplatelet therapy (clopidogrel). On T1 images, a pale high-intensity area was documented at the dissected lesion at 19 days after admission. Thereafter, the right PICA was gradually depicted on MRA and completely visualized at 5 months after the onset. In parallel with that, the high-intensity signal area on T1-VISTA gradually decreased in size and disappeared by 5 months after the onset (Fig. ). Clopidogrel administration was then stopped.
A 64-year-old man, who had a history of hypertension, presented with headache and vomiting. CT scan showed SAH in the superior cerebellar cisterns []. DSA done revealed a fusiform aneurysm of the distal SCA, predominantly involving the branch of the cortical segment [Figures and ]. Standard heparin protocol was followed and an activated clotting time greater than 250 s was maintained during the procedure. 5F Envoy (cordis) guiding catheter was inserted in the distal vertebral artery. The aneurysm was accessed with a combination of micro-catheter (echelon-10) and micro-wire (traxcess12). Meticulous pre-shaping of the micro-catheter according to the shape of the target aneurysm aided in proper positioning of the micro-catheter in the aneurysm which was subsequently packed densely with the platinum micro-coils. Post-procedure angiogram showed complete exclusion of the aneurysm along with the branch of the cortical segment and preservation of the flow in the superior cerebellar artery (SCA) []. There were no untoward events in the post-procedure hospital stay and patient was discharged after 1 week. No neurological deficit was seen during the clinical follow-up after 1 month. Control angiogram carried out after 1 year showed stable occlusion of the aneurysm with preservation of the ante-grade flow in the SCA [].