A 46-year-old male patient presented to us with blurring of vision OS since 2 months. His BCVA was 6/6, N6 in OD and 6/12, N8 in OS at presentation. Fundus examination of OS showed an irregular elevated, yellowish-white choroidal lesion with welldefined geographic borders involving the inferior macula with areas of subretinal hemorrhage at and above the fovea suggestive associated choroidal neovascular membrane. SD-OCT showed a dense hyper-reflective choroidal mass with significant widening of the choroidal layers. B-scan ultrasonography revealed high-spike echoes through the lesion suggesting choroidal osteoma. FFA in that area showed staining conforming to the diagnosis of choroidal osteoma with a secondary CNVM. Patient underwent treatment with multiple antiVEGF injections and standard fluence photodynamic therapy (PDT). The patient developed an acquired FCE after 17 months of treatment [].
The chief complaint for this 29-year-old woman was impaired vision in her left eye. At the initial visit for this this patient, a photograph of her left fundus showed white dots (Figure B) with hyperautofluorescence on FAF (Figure D), while OCT revealed a disrupted or irregular photoreceptor inner outer segment (IS/OS) junction (Figure F) indicated by the arrows. At 1 month after her initial visit, this patient complained of metamorphopsia in her right eye. FP showed that there were white dots in the posterior pole (Figure A), while FAF images obtained using FAF revealed hyperfluorescence in the area surrounding the optic disc (Figure C). OCT showed a disrupted or irregular photoreceptor IS/OS junction in both eyes (Figure E and F) indicated by the arrows. At 4 months after her initial visit, there was almost complete improvement of the metamorphopsia in her right and left eyes. In addition, OCT indicated there was ongoing restoration of the IS/OS line in both eyes (Figure A and B). Although the deviation map of ganglion cell analysis showed there was a decrease of the GCL + IPL thickness in both eyes at her initial visit, her right eye was not affected. During the 4 months of follow-up, the deviation map (Figure C~J) did not indicate any recovery of the decreased GCL + IPL thickness. Signal strengths of all the Cirrus OCT measurements were 10/10.