A 23-year-old female with B. cenocepacia developed an erythematous maculopapular rash on the lower legs with associated arthropathy of her finger joints. This was clinically felt to be reactive leucocytoclastic vaculitis and a biopsy was not conducted. The vasculitis did not respond initially to oral prednisolone, and she was then commenced on azathioprine and the rash responded to this. Two years later, she died following a severe infective exacerbation of her chest.
A 26-year-old female with Burkholderia cenocepacia presented with a two-month history of worsening fixed purpuric rash on the lower legs (). Skin biopsy confirmed leucocytoclastic vasculitis. She was treated with dapsone initially without improvement. On commencement of oral prednisolone, there was minimal improvement, which remained stable. Following this, she was managed with topical protopic 0.1%.