A 48-year-old male patient, a known hypertensive and diabetic, was admitted in August 2014, with a serum creatinine of 6.9 mg/dl and 3+ proteinuria. He was diagnosed as having AERD by kidney biopsy. There was no predisposing factor for AERD in this patient.
In May 2017, a 73-year-old male patient developed breathlessness. His echocardiography study showed global hypokinesia and ejection fraction of 45%. Cardiac angiogram was done and was started on aspirin. His creatinine increased from 1.7 mg/dl to 9.6 mg/dl. He was started on hemodialysis. He was diagnosed as having AERD by renal biopsy.