Mrs. K, a 27-year-old pregnant woman at 27+4 weeks of gestation, presented to our obstetric emergency unit with tachypnea (RR 28×/min; saturation 92%) one day before admission. The patient also had a fever (103.1 °F) and cough 1 week before admission. Other than that, she also had chronic hypertension. A chest X-ray showed patchy consolidation that corresponded to bilateral pneumonia. A naso-oropharyngeal swab for SARS-CoV-2 was positive as tested by RT-PCR (RdRP Cq 35.15; E Gene Cq 32.10). The patient was taken care of in the High Care Unit (HCU) with oxygen therapy using 10 L per minute (Lpm) with a nonrebreathing mask (NRM), and O2 saturation maintained at 95–97%. She was diagnosed with acute respiratory distress and superimposed preeclampsia with severe features. The patient was treated with anti-hypertension (nifedipine 4 × 10 mg), MgSO4 for seizure prevention, and dexamethasone 2 × 6 mg for lung maturation for 2 days.\nOn hospital care day 2, tachypnea worsened (RR 32×/min), with a decreased O2 saturation to 90% while on oxygen therapy given at 10 Lpm with NRM. The patient had an emergency cesarean section, and a baby girl was born with a birthweight of 1150 g, birth length of 34 cm, and APGAR score (AS) 7/9. The baby was taken care of in the NICU isolation for COVID-19 as a naso-oropharyngeal swab for SARS-CoV-2 result was negative.\nFor postoperative observation, the patient was taken to HCU with no clinical improvement. On hospital care day 7 (HD 7), she was given Remdesivir protocol for 5 days. Tachypnea and saturation improved on HD 8 (RR 24×/min; O2 saturation 96% with NRM 6 Lpm). Both patient and baby were discharged on HD 12 after the SARS-CoV-2 swab came back negative.
Mrs. T, a 30-year-old at 32 weeks gestation with two histories of cesarean section, presented to our obstetric emergency unit with tachypnea (RR 30×/min; O2 saturation 93%), cough, and fever (102.2 °F). The patient had complained of tachypnea for 7 days before admission. Her naso-oropharyngeal swab was positive for SARS-CoV-2 by real-time PCR (RdRP Cq 26.09; E Gene Cq 26.10) without abnormalities in a chest X-ray.\nThe patient was treated in HCU and was given oxygen therapy 4 Lpm with a nasal cannula, and O2 saturation was maintained at 95%. Remdesivir was given on HD 1 and continued for 6 days (HD 6). During hospitalization, the fetal condition was observed using cardiotocography, and no abnormalities were seen. Clinical symptoms improved, and the patient was discharged on HD 7 with a negative result from a naso-oropharyngeal swab for SARS-CoV-2. The patient underwent a cesarean section at 39 weeks gestation due to a previous cesarean section. A baby girl was born, 2700 g, 49 cm, A/S 9/10. The baby was rooming with her mother after delivery.