Case 1: A 38-year-old male (weight 75 kg, ASA status III) was scheduled for right total hip arthroplasty (THA) due to severe bilateral rigid and sore hip joints. He had a history of ankylosing spondylitis for more than 18 years. Despite a long term usage of sulfasalazine and “painkiller”, the patient developed a rigid kyphotic and scoliotic deformity. An overall physical examination revealed rheumatoid arthritis involved most articles in the body resulting in limited movement and swelling of interphalangeal joints, metacarpophalangeal joints, elbow joints, shoulder joints, and ankle joints, with rigid bilateral hip and knee joints preventing any walk. The airway assessment revealed a Mallampati class III, interincisor distance of 3 cm, and rigid neck incapable of any movement. X-ray of his cervical, thoracic and lumbar vertebrae and pelvis revealed a loss of physiological curvature of the vertebral column, kyphosis, hyperplasia at the edge of the vertebrae, “bamboo” like bony bridge, blurred facet joints, and calcification of ligament, a fusion of both sacroiliac joints, rough articular face and narrowed articular cavity and hyperplasia of both hip joints (Fig. ). After administration, he received immunosuppressive therapy, with prednisone 20 mg per day, and methotrexate 10 mg once per week, and anti-TNF therapy with etanercept (TNF receptor fusion protein) 25 mg i.h. twice per week, and anticoagulation therapy with low-molecular-weight heparin 4000 U per day.
Case 4: A 65 years old male (weight 76 kg, ASA status III) was scheduled for left THA. He was diagnosed with AS for 10 years, and developed necrosis of both femoral heads, and could not walk because of pain in the left hip joint. He had a history of hypertension for 10 years, and diabetes mellitus for 7 years, and smoking history for 50 years with nearly 50 cigarettes per day. A chest X-ray revealed enhanced texture of bilateral lungs and right pleural effusion. X-ray of his pelvic revealed bilateral femoral head necrosis, narrowed joint space, osteoproliferation and bone defect under articular surface of bilateral sacra-iliac joints and hip joints, and bamboo-like changes of lower lumbar spine.