The patient was a 22-year-old woman who referred for mandibular right wisdom tooth removal. Lidocaine 2% and epinephrine 1:80,000 were used for inferior alveolar nerve block. Facial, buccal, and palatal blanching occurred on the side of injection. She felt numbness in the periorbital and lower lip. The color of the face returned to preinjection condition after 10minutes [].
A 32-year-old female patient in healthy conditions attended for extraction of second maxillary right premolar. Immediately after buccal infiltration, a white patch appeared lateral to the nasolabial fold [].