A 39 year-old male without past notable medical history was admitted with a sudden headache and neck stiffness. Brain computed tomography (CT) demonstrated evidence of Fisher Grade III subarachnoid hemorrhage (SAH) predominance of the pre-pontine, left ambient and quadrigeminal cistern (), and a fusiform aneurysm of a left distal SCA was revealed on the CT angiography (). Subsequent digital subtraction angiography (DSA) revealed the fusiform dilatation (12 mm length; 4.5 mm width) involving the ambient segment of the left distal SCA. The left SCA was duplicated ahead of the aneurysm and there was sufficient collateral circulation from the ipsilateral anterior inferior cerebellar artery (AICA) and posterior inferior cerebellar artery (PICA) (). The aneurysm was treated by endovascular occlusion of the aneurysm sac and the involved branch. Under general anesthesia an Excelsior SL-10 microcatheter was used to access the aneurysm. Seven detachable platinum coils were used to obliterate the lesion. Post-procedural angiography showed complete occlusion of the aneurysm sac and involved the SCA branch (). There was no immediate complication after embolization. Diffusion MRI was done 8 hours after embolization. MRI revealed scattered high signal change on the left posterior tegmentum, superior vermis, and superior part of the left cerebellum (). Left sixth nerve palsy occurred in the patient 1 day after EVT. The symptom completely recovered within 1 week of the post-procedural period. No neurological deficit was seen during the clinical 3-month follow-up.
A 56-year-old woman began to suffer from an occipital headache for 7 days before admission to our hospital, and dizziness appeared 5 days later. On admission, she complained of dizziness and a mild occipital headache. She showed nystagmus and the right nose-finger-nose test was positive. In peripheral blood cell counts and biochemical studies, elevations in white blood cells (9,200/μl) and low-density lipoprotein cholesterol (215 mg/dl) were observed. Coagulation studies and immunological studies were normal. Head computed tomography (CT) showed low-density areas in the right cerebellar hemisphere, diffusion weighted imaging (DWI) of magnetic resonance imaging (MRI) displayed high-intensity signal areas in the cerebellar vermis and the right cerebellar hemisphere (Fig. ). In addition, a high-intensity signal area was observed just adjacent to the right VA on T1-VISTA (Fig. ), whereas no such high intensity was detected on conventional T1 image. Conventional MRA did not depict the right PICA or any abnormal findings of the right VA (Fig. ). Echocardiography and 24-hour electrocardiography showed no findings suggestive of cardioembolic causes. According to these findings, ischemic stroke of the cerebellum induced by the right PICA-D was diagnosed, and after confirming that she had neither hypertension nor aneurysmal formation, combined therapy with clopidogrel and unfractionated heparin administration was started. T1-VISTA showed a slight expansion of the high-intensity area at 3 days after admission, but still no lesions on T1 images. At 9 days after admission, cerebral angiography revealed the “pearl and string sign” at the proximal portion of the right PICA (Fig. ). At 12 days after admission, the patient was discharged with single antiplatelet therapy (clopidogrel). On T1 images, a pale high-intensity area was documented at the dissected lesion at 19 days after admission. Thereafter, the right PICA was gradually depicted on MRA and completely visualized at 5 months after the onset. In parallel with that, the high-intensity signal area on T1-VISTA gradually decreased in size and disappeared by 5 months after the onset (Fig. ). Clopidogrel administration was then stopped.