The fourth patient was a 28 year old female who has been referred because of Macrocystic Anemia, thrombocytopenia and low Retic counts. During 6 months follow up interval, patient affected by neck mass and she was diagnosed as Hodgkin lymphoma. However she no need to blood transfusion but MDS criteria () disappeared after treatment of oncology disease.
The second patient was a 49 year old man who was referred to clinic because of Macrocytic Anemia and low Retic count and he underwent BMA and BMB because of Anemia continuity and has diagnosed as MDS in BMA (, ).\nDuring follow up period, patient required blood injection once each 15 days, so thalidomide was started for him. He had frequent infections because of leukopenia and had a history of hospitalization. During follow up period and after 1.5 months of thalidomide initiation and 9 months later, he was affected by colon cancer and had no problem in CBC diff. after treatment of colon cancer.