A 67-year-old man was admitted to our hospital with headache and weakened left limbs. Muscle strength on the left side was grade 4. Routine MRI displayed a mass lesion close to the posterior horn of the right lateral ventricle with low T1-signal intensity and high T2-signal intensity. Peritumoral edema was markedly presented and showed lower FA (0.08-0.22) compared to the contralateral whiter matter (0.40). Fibers displayed interruption distally to the right CST (fig. ) and did not significantly improve using an FA cut-off value of 0.10 for fiber-tracking. The mass was confirmed to be a metastatic tumor from a renal cell carcinoma of the right kidney after histopathological findings.
A 37-year-old man was admitted to our hospital with weakness of the right limbs and speech and memory loss. Muscle strength in the right-side extremities was grade 4 according to Lovett's testing. A mass lesion involving the left basal ganglia, thalamus and internal capsule was detected on routine magnetic resonance imaging (MRI) with low T1-signal intensity and high T2-signal intensity. The DTI showed a lower value of FA in the affected white matter (0.08-0.24) compared to the contralateral side. DTI-based fiber-tracking displayed a reduced fiber tract on the left CST, and partially interrupted in the lesion area (fig. ). Fiber bundles slightly increased but were still interrupted using an FA cut-off value of 0.10 for fiber-tracking. Diagnosis of diffuse astrocytoma was made after biopsy and histopathological results.