A 5-year-old girl with a patch of kinky hair in the right parietal region, which had been present since the age of 4 months and different colored eyes since birth referred to our clinic []. The underlying scalp was normal. The affected hair appeared smaller in diameter and lighter than the normal hair color and no structural hair abnormalities were detected under the light microscope. She had slightly hyperpigmented linear lesions mostly marked on the anterolateral of the right arm with midline pectoral and abdominal extension []. The right eye was diffusely brown, and the left was green []. No ophthalmologic, cardiac, neurological or skeletal abnormalities were observed. Nails and teeth were normal. The patient was diagnosed with a woolly hair nevus of the right parietal scalp associated pigmented demarcation lines and heterochromia iridis.
A 30 year-old Brazilian woman of skin phototype IV and pregnant for 35 weeks sought medical care for presenting hyperchromic lines on both legs for 5 weeks. Hyperchromia in the axillae and groin, which had appeared earlier in the pregnancy, were concurrent complaints. There were no associated symptoms. She had a history of gestational diabetes, which was been treated with NPH insulin since the 26th week of pregnancy and was under control. It was her second pregnancy, and she denied similar alterations in the previous one. Hormonal disorders had been previously discarded by an endocrinologist. Physical examination revealed demarcation lines from the perineum to the posteromedial portion of the thighs extending to the ankles through the popliteal fossae, bilaterally and symmetrically, in the interface between a hyperchromic lateral portion and a lighter medial portion ( and ). Hyperchromic axillae and prominent linea alba were also seen.