A 27-year-old Caucasian female was referred to the Stomatology and Dental Medicine Department (CESPU) of the Centro Hospitalar de São João, Pólo de Valongo, Oporto, Portugal. Her chief complaint was of a “dark-colour lower gum” and she made the request for rapid cosmetic therapy. She reported noticing darkening of the teeth and gums for over two years, mainly in the mandible. No symptoms and no significant personal or family history were present. The patient denied taking any medication or any other dark pigmentation in other locations. Her blood pressure was within the normal range of values. She had stopped smoking a year before the consultation, although she had smoked 30 cigarettes per day for more than 10 years. On oral examination two black-brown macules measuring 1 × 1 cm were detected in the vestibular attached lower gingiva (). There was no lymphadenopathy or salivary gland abnormalities detected. Previous incisional biopsy to rule out any malignancy and blood investigations (complete full blood count and general biochemistry, including cortisol and ACTH serum levels) showed no abnormalities or potential causes. A diagnosis of smoker's melanosis was given based on the smoking history and the absence of any abnormalities seen in previous investigations. After explaining the benign character of the pigmentation, the patient requested the elimination of the pigmentation by aesthetic reasons due to professional work issues. A CO2 laser vaporization for gingival depigmentation was proposed. The vaporization of the pigmentation was performed under local anaesthesia (2% lidocaine with 1 : 100,000 epinephrine) with CO2 laser (10600 nm) (DEKA Smart US20D, Florence, Italy), with angulated mirror, focus spot of 1 mm, pulsed mode (50 Hz), 4.5 W of output power, power density of 573.25 W/cm2, and fluence of 11.46 J/cm2 (). During this procedure, safety precautions were in place to protect the operator, assistant, and patient. With this laser procedure, the secondary-intention healing of the surgical wound was reached without any dressing (). Paracetamol (1 g every 12 hours) was prescribed for two days to be taken only if she developed painful symptoms. After 3 weeks, wound healing was completed uneventfully without any melanin pigmentation (). She did not report any postoperative pain, swelling, or other complications. After two years of follow-up, the patient had no symptoms or signs of gingival melanin pigmentation.
A 23-year-old male patient complaining of heavily pigmented gums [] visited department of Periodontics, Institute of Dental Studies and Technologies, Modinagar. On examination, the patient was otherwise healthy but had a deeply pigmented gingiva. Pigmentation was unsightly and hence laser depigmentation procedures were planned. The procedure was explained verbally to the patient and the consent was obtained.\nPatient and operating staff wore special diode-laser protective eye glasses. Highly reflective instruments or instruments with mirrored surfaces were avoided as there could be reflection of the laser beam. A semiconductor diode surgical laser unit (Sunny Gold; Mikro Scientific Instrument Pvt Ltd., India, wavelength 980 nm, power 2-4 W) was used for depigmentation of the maxillary and mandibular anterior gingiva up to the second premolar on both right and left sides. The semiconductor diode laser was emitted in gated-pulsed mode, and was operated in a contact method using a flexible fiber optic handpiece. The Laser settings used were: fluence between 5 and 15 J/cm2, pulse length between 20 and 50 ms, spot diameter of 2 mm and thermal relaxation times of 0.15 to 0.20 milliseconds. No topical or local anesthesia was given to patients. Laser ablation started from the mucogingival junction toward the free gingival margin, including papillae. The motion of ablation was circular with overlapping circles. High attention was taken to avoid passing the laser beam on teeth structures and over mucosa. During the procedure, laser ablated the gingival epithelial surface little by little to reach the pigments without causing any bleeding which was beneficial for clear visualization. [] To enhance visualization, normal saline-soaked cotton or gauze was used to remove epithelial remnant.\nThe ablation of the gingiva was completed within 20-25 minutes on the maxilla and mandible. Laser ablation of pigmented epithelium immediately produced a melanin pigment-free surface without any carbonization. The wound looked fresh with no bleeding []. There was no need to apply a periodontal dressing. Patient was instructed to avoid smoking and eating of hot and spicy foods for the first 24 hours and was discharged from dental office to perform normal daily activity. Healing was good at 1 month with pink color comparable to nearby non-treated area, resulting in a significant improvement in aesthetic appearance []. No infection or significant postoperative complications such as pain or bleeding were encountered. Fifteen months follow-up showed no signs of recurrence of pigmentaion.