This is a 65-year-old man known to have chronic myeloid leukemia (CML) on dasatinib. He presented with a short history of fever, productive cough, and dyspnea. The examination revealed low-grade fever, tachycardia, and bilateral rhonchi on chest examination. Chest X-ray showed bilateral lower lobe consolidation with effusion. SARS-CoV-2 PCR was positive, and he was subsequently diagnosed as a severe case of COVID-19 pneumonia and received antibiotics and antiviral drugs. His condition deteriorated further during his stay, requiring noninvasive ventilation and ICU admission for 7 days. He eventually improved and was stepped down to the general medical wards for post-ICU care. He continued to have positive PCR for 54 days from the initial positive test.
The first case is a 74-year-old man known to have asthma, diabetes mellitus (DM), hypertension (HTN), coronary artery disease (CAD), and dyslipidemia (). He was admitted to a quarantine facility because of an asymptomatic COVID-19 infection identified through screening (RT-PCR). The local guideline at the time warranted two negative PCR swabs before discharge. SARS-CoV-2 was repeatedly positive for 49 days. He showed clinical improvement and was discharged after negative results ().