A 37-year-old man was admitted to our hospital with weakness of the right limbs and speech and memory loss. Muscle strength in the right-side extremities was grade 4 according to Lovett's testing. A mass lesion involving the left basal ganglia, thalamus and internal capsule was detected on routine magnetic resonance imaging (MRI) with low T1-signal intensity and high T2-signal intensity. The DTI showed a lower value of FA in the affected white matter (0.08-0.24) compared to the contralateral side. DTI-based fiber-tracking displayed a reduced fiber tract on the left CST, and partially interrupted in the lesion area (fig. ). Fiber bundles slightly increased but were still interrupted using an FA cut-off value of 0.10 for fiber-tracking. Diagnosis of diffuse astrocytoma was made after biopsy and histopathological results.
A 24-year-old male presented with right frontal-parietal glioblastoma. The FA and color-coded maps showed decreased FA value and destruction of white matter fibers. 3D tractography was initiated from the brain stem for CST. The right CST passing through the periphery of the lesion was compressed and deviated anteromedially by the lesion. The AF was compressed and deviated superiorly by the lesion, and was close to the tumor margin (Figure ).