A 47-year-old Caucasian male with a schizoaffective disorder diagnosis presented consistently elevated leukocyte counts over a three-year period. Along with clozapine, his pharmacotherapy comprised oxcarbazepine, biperiden, promazine, delorazepam and clonazepam. His medical history was relevant for concomitant use of various substances of abuse (e.g., cocaine, amphetamine, heroin), and chronic Hepatitis C Virus (HCV) infection, although no additional information was available regarding the activity of the infection.
A 57-year-old Caucasian female with a diagnosis of SCZ and mild intellectual disability presented frequent fluctuations in the leukocyte counts, with values ranging from normal to moderately elevated. Her past medical history was significant for a diagnosis of epilepsy. Along with clozapine, her pharmacotherapy comprised gabapentin, fenobarbital, biperidene, risperidone and clonazepam.