Case 5 was a 15 years old male who presented with epigastric pain, fever, shortness of breath, chest pain, 5 kg weight loss, hypereosinophilia, ascites, and pleural effusion. The stool tests for Fasciola were initially negative, but the Fas2 ELISA was positive. He was treated with a single dose of veterinary formulation triclabendazole with partial improvement of symptoms. His follow up stool tests were positive and remained positive since then despite 3 courses of triclabendazole (2 doses of 10 mg/kg every 12 hours each), and a course of 2 doses of triclabendazole 10 mg/kg every 12 hours in combination with nitaxozanide 500 mg every 12 hours for 7 days.
Case 6 was a 12 years old male brother of case 5 diagnosed with asymptomatic F. hepatica infection. He failed the initial treatment with a single dose of triclabendazole. He was prescribed and failed 2 additional triclabendazole courses (2 doses of 10 mg/kg every 12 hours). He was subsequently treated with 2 doses of triclabendazole 10 mg/kg every 12 hours followed by nitaxozanide 500 mg every 12 hours for 7 days but his stool tests have remained positive for Fasciola eggs.