A 17-year-old female presented with metamorphopsia and blurred vision in right eye (OD) since 1 week. Her best corrected visual acuity (BCVA) was 6/9;N8 in OD and 6/6;N6 in left eye (OS). Clinical examination revealed findings suggestive of choroidal neovascular membrane (CNVM). Her spectral-domain optical coherence tomography (SD-OCT) showed an active Type 2 CNVM associated with a FCE, which was confirmed by fundus fluorescein angiography (FFA). She was treated with multiple intravitreal antiVEGF injections. At her follow-up visits there was significant CNVM resolution, but FCE was progressively increasing in depth, as measured from a horizontal line drawn at the level of RPE to the inner margin of FCE, from 121 μm to 256 μm over the period of 2 years, possibly due to the contraction of the underlying scar [].
The chief complaint for this 29-year-old woman was impaired vision in her left eye. At the initial visit for this this patient, a photograph of her left fundus showed white dots (Figure B) with hyperautofluorescence on FAF (Figure D), while OCT revealed a disrupted or irregular photoreceptor inner outer segment (IS/OS) junction (Figure F) indicated by the arrows. At 1 month after her initial visit, this patient complained of metamorphopsia in her right eye. FP showed that there were white dots in the posterior pole (Figure A), while FAF images obtained using FAF revealed hyperfluorescence in the area surrounding the optic disc (Figure C). OCT showed a disrupted or irregular photoreceptor IS/OS junction in both eyes (Figure E and F) indicated by the arrows. At 4 months after her initial visit, there was almost complete improvement of the metamorphopsia in her right and left eyes. In addition, OCT indicated there was ongoing restoration of the IS/OS line in both eyes (Figure A and B). Although the deviation map of ganglion cell analysis showed there was a decrease of the GCL + IPL thickness in both eyes at her initial visit, her right eye was not affected. During the 4 months of follow-up, the deviation map (Figure C~J) did not indicate any recovery of the decreased GCL + IPL thickness. Signal strengths of all the Cirrus OCT measurements were 10/10.