A 7-day old female patient was referred by her neonatologist with a suspicion of a congenital anal fissure. During examination we found a perineal groove. She was born to a 26-year-old gravida 1 para 1 woman who did not take folic acid during her pregnancy. The patient was not noted to have any other associated anomalies during her exam.\nShe was followed up regularly for 2 years, and it was noted that the perineal groove spontaneously resolved.
A 2-month-old female patient presented with a perineal groove. The patient was already known to have a mild ventricular septal defect (VSD). She was born to a 40-year-old mother gravida 2 para 2. The mother did not take folic acid during her pregnancy.\nWe conducted follow-ups for 18 months. The VSD naturally closed at 9 months of age. The perineal groove also spontaneously resolved at 16 months of age.