Mrs. T, a 30-year-old at 32 weeks gestation with two histories of cesarean section, presented to our obstetric emergency unit with tachypnea (RR 30×/min; O2 saturation 93%), cough, and fever (102.2 °F). The patient had complained of tachypnea for 7 days before admission. Her naso-oropharyngeal swab was positive for SARS-CoV-2 by real-time PCR (RdRP Cq 26.09; E Gene Cq 26.10) without abnormalities in a chest X-ray.\nThe patient was treated in HCU and was given oxygen therapy 4 Lpm with a nasal cannula, and O2 saturation was maintained at 95%. Remdesivir was given on HD 1 and continued for 6 days (HD 6). During hospitalization, the fetal condition was observed using cardiotocography, and no abnormalities were seen. Clinical symptoms improved, and the patient was discharged on HD 7 with a negative result from a naso-oropharyngeal swab for SARS-CoV-2. The patient underwent a cesarean section at 39 weeks gestation due to a previous cesarean section. A baby girl was born, 2700 g, 49 cm, A/S 9/10. The baby was rooming with her mother after delivery.
Mrs. A, a 35-year-old at 27 weeks gestation, was referred to our institution with a fever (101.3 °F), flu-like syndrome, tachypnea (RR 28×/min; O2 saturation 94% room air), and anosmia. The patient had complained of symptoms for 4 days before admission. A chest X-ray was normal. A naso-oropharyngeal swab was positive for SARS-CoV-2 by real-time PCR (RdRP Cq 15.21; E Gene Cq 15.58) without abnormalities in a chest X-ray.\nThe patient was taken care of in an isolation ward for COVID-19 and given oxygen therapy 4 Lpm with a nasal cannula (saturation 96–97%). Remdesivir was given on HD 1 until HD 6. Daily fetal monitoring was performed using a fetal doppler and fetal kick count chart. During hospitalization, clinical symptoms improved. The patient was discharged after 7 days of hospitalization with a repeated naso-oropharyngeal swab for SARS-CoV-2 result which came back negative. The patient underwent vaginal delivery at 37 weeks gestation. A baby boy was born, 3100 g, 51 cm, A/S 8/9. Both mother and baby were in good condition after delivery.\nRemdesivir Protocol:\nDay 1: 200 mg IV single dose\nDay 2–5: 100 mg IV/daily