A 73-year-old female presented as an outpatient from her primary care physician for a CT of the thorax, abdomen, and pelvis to evaluate a reportedly stable abdominal aortic aneurysm. Pertinent past medical history revealed a left supraclinoid internal carotid artery aneurysm, a stable infrarenal abdominal aortic aneurysm, systemic lupus erythematous/rheumatoid arthritis overlap syndrome, smoldering IgG lambda myeloma, chronic kidney disease (stage II), hyperparathyroidism, and a cerebral infarction in the right posterior cerebral artery territory in 2009. Findings on the CT of the thorax demonstrated a fusiform superior vena cava (SVC) aneurysm measuring 5.9 × 4.4 × 6.1 cm (anterior-posterior × transverse × craniocaudal). No thrombus was noted within the SVC aneurysm (). The aneurysm was first partially visualized in 2007 on a cervical spine CT, and since that time it had remained stable on annual follow-up CTs.\nThe patient's course between 2007 and the most recent study in 2016 included an extensive rheumatologic and hematologic workup, including a temporal artery biopsy in 2015. Pathology revealed intimal hyperplasia with focal internal membrane disruption, but no features of granulomatous vasculitis were identified.\nThe etiology of the SVC aneurysm in this patient is uncertain. Potential causes in this patient include autoimmune disease (RA/SLE), which seems unlikely. Pathology did not reveal any convincing evidence of vasculitis. The arterial aneurysms are also felt to be unrelated as the patient has significant atherosclerotic disease. While an iatrogenic cause is possible, a chart review did not elicit any complications relating to prior hemodialysis catheter placement. Therefore, we surmised that the SVC aneurysm was likely idiopathic.\nThis patient did not receive any anticoagulation to prevent thrombus formation within the SVC aneurysm, and no repair was ever attempted. For the six years during which the patient was under observation at our institution, an SVC thrombus or sequela of an embolus originating from the SVC has never been observed. While the patient had a cerebral infarct in 2009, there was no evidence of right to left circulatory shunt. The observatory management of the SVC aneurysm in this patient stands in contrast with the majority of the cases found in the literature. Most patients were treated prophylactically for theoretical complication.
A 58 years-old man presented at our emergency room with fever, cough and left thoracic pain. His past medical history was unremarkable. Blood test showed WBC and C-reactive protein elevation. He had started antibiotics therapy and, given the persistence of symptoms, CT scan was performed showing lower left pneumonia. Incidentally, a 2.5 cm mass was found in the upper anterior mediastinum, with positive contrast enhancement and a 5 mm vessel arising from left brachio-cephalic vein (, ). Because of size and position fine needle aspiration nor anterior mediastinotomy were performed. Radiologic features were consistent with thymoma that usually appears as an ovoid or lobulated, smooth, well-marginated mass, projecting over the mediastinum typically protruding unilaterally, therefore patient underwent (1) neurologic evaluation that excluded myasthenia (2) PET/CT scan that showed the absence of any pathological uptake. However, thymoma was felt to remain a diagnostic possibility and patient was referred for radical surgery, with particular attention to abnormal vascularization. He underwent left thoracoscopy and, in spite of extreme attention, during pleural dissection between mediastinum and sternum, a sudden massive bleeding occurred (about 1,500 cc) requiring emergency conversion to median sternotomy. It was then clear that the bleeding came from tumor and not from brachiocephalic vein or its branches, as initially thought. After controlling the bleeding, we removed the mass but it was necessary to sacrifice the left laryngeal nerve.\nIntra-operative emergency required significant blood transfusions and precautionary transfer in intensive care for 24 h. The patient eventually made a complete recovery. We only recorded transitory dysphonia as in case of laryngeal nerve paralysis. At specimen analysis, the cut surface seemed to have some fresh blood and the soft tissue was taupe with multifocal thrombosis in various stages of organization up to phlebolithes. Histopathologically, it was diagnosed a residual thymic tissue surrounded by lipomatous hyperplasia with venous malformation consisting essentially of a large number of dilated vessels with a single layer of endothelial cells with no signs of atypia or mitosis. Most of the channels contained red blood cells in the cavity. Margins were free. Definitive histology was a 7 cm fatty specimen enclosing a 2.5 cm in size mass diagnostic for residual thymus associated with venous vascular malformation (ISSVA classification, 2008).