A 72-year-old woman with the initial diagnosis of a malignant melanoma on the right lower leg presented to our clinic after an in sano excision in a clinic alio loco. However, after further excision of the melanoma, we closed the wound using skin mesh-graft. After complete wound healing, the patient received a low-dose interferon therapy with Roferon. After 3 months, the patients presented to us with worsening of the wound condition and a reappearance of activated melanoma in situ of the scar on the right lower leg. Therefore, a radical excision of the pretibial scar and a temporary covering with alloplastic material was performed. After several debridements, a clean granulating wound could be achieved making it possible to cover the defect of the lower leg with a free radial forearm flap from the right forearm. Finally, the patient could be discharged with normal wound healing from our department and received further chemotherapy without any sign of re-appearance of the malignant melanoma so far.
A 46-year-old male was presented to us with the fatal diagnosis of Fournier’s gangrene after receiving his first episodes of chemotherapy comprising of vincristine and prednisone due to a non-Hodgkin lymphoma. After an immediate debridement of the necrotic scrotal area reconstructive surgery was performed already two days later with loco-regional flaps from both sides. With good wound healing and stabilized overall condition, the patient could be discharged to rehab after being hospitalized for more than 12 weeks.