A 68-year-old male complained of superficial but nodular swelling in the right parotid region. The patient complained of pain in ear and the swelling. The swelling measured 3 cm in diameter with restricted mobility and showed erythematous skin over it. The examination of ear, nose and throat was reported to be normal. The patient was advised to be assessed by USG-guided FNAC. The aspirate revealed dissociated to polygonal cells carrying centrally placed hyperchromatic nuclei with rounds prominent nucleoli. Few of the cells showed bi-nucleation. The cytoplasm of these cells carried granules of altered hue. The background showed infrequent melanin containing macrophages []. Cytodiagnosis of melanoma was made with advice to search for primary of melanoma. The re-examination showed 1 cm size of brown-colored tumorous lesion uncomplained by the patient. This primary lesion of the scalp underwent FNAC followed by excision revealing similar diagnosis of melanoma on both occasions.
A 56-year-old female came with the chief complaints of deep nodular swelling in the left parotid region. The examination of the nodule revealed firm to hard in consistency with restricted mobility. The swelling was solitary. FNAC was carried out. Smears revealed discohesive cell sheets with internal attempted ducts. The cells carried hyperchromatic pleomorphic nuclei with irregular chromatin and infrequent nucleoli. The nuclei of the cell sheets showed rare mitosis. The background was hemorrhagic with dissociated malignant cells. The diagnosis of metastases of well-differentiated ductal carcinoma was presented [] with advice to search for primary in the breast. On examination, left breast revealed 1.5 cm lump in the upper outer quadrant. The lump underwent FNAC followed by tru-cut biopsy. The offered diagnosis on these investigations was of well-differentiated ductal carcinoma. The patient later underwent surgical management for the lump in the left breast.