A 26-year-old male presented with multiple skin-colored umbilicated papules on the penis, without itch and pain (). The lesions first appeared as one skin-colored papule on the penis shaft for the past 1 month PTC. Over time, 3 weeks after, the skin lesions were spread over the base of the penis and increase in number. There was a history of promiscuity with several female prostitutes. Physical examination on the shaft and the base of the penis revealed several papules with central umbilication. VDRL, TPHA, and HIV tests were nonreactive. The patient was treated with 20% KOH solution applied by the patient twice daily for the lesions. All of the MC lesions disappeared on day 20 of observation. The patient felt a stinging sensation after 3–5 minutes application of the 20% KOH solution. Furthermore, it also caused other side effects such as erosions and post-inflammatory hypopigmentation.
A 28-year-old male presented with multiple skin-colored papules with umbilication on the face, especially forehead and temple area, without itch and pain (). The lesions first appeared as skin-colored papules on the forehead for the past one-month PTC. Two weeks later, the number of papules increasing and spread to the temple area. There was a history of promiscuity with female prostitutes. He had no concern of his sexual partners who also have the same lesions. Physical examination on the forehead and the temple area showed many papules with skin-colored and central umbilication. The HIV test was reactive, otherwise VDRL and TPHA tests were nonreactive. The patient was treated with 20% KOH solution applied by the patient twice daily. He complained stinging and burning sensation after 20% KOH applied for 3 minutes. The patient died due to brain toxoplasmosis on day 7 observations, but almost all the lesions became smaller.