A 17-year-old female presented with metamorphopsia and blurred vision in right eye (OD) since 1 week. Her best corrected visual acuity (BCVA) was 6/9;N8 in OD and 6/6;N6 in left eye (OS). Clinical examination revealed findings suggestive of choroidal neovascular membrane (CNVM). Her spectral-domain optical coherence tomography (SD-OCT) showed an active Type 2 CNVM associated with a FCE, which was confirmed by fundus fluorescein angiography (FFA). She was treated with multiple intravitreal antiVEGF injections. At her follow-up visits there was significant CNVM resolution, but FCE was progressively increasing in depth, as measured from a horizontal line drawn at the level of RPE to the inner margin of FCE, from 121 μm to 256 μm over the period of 2 years, possibly due to the contraction of the underlying scar [].
The chief complaint for this 41-year-old woman was impaired vision in her right eye. A photograph of her right fundus showed the presence of yellow dots (Figure A). A visual field test during the initial visit indicated there was an enlarged blind spot in her right eye (Figure C). In addition, OCT also revealed a disrupted or irregular photoreceptor inner outer segment (IS/OS) junction in right eye (Figure A) indicated by the arrows, although the IS/OS junction in left eye was normal (Figure B). After 4 months, the IS/OS junction in her affected eye was restored (Figure D). At her initial visit, the deviation map of the ganglion cell analysis showed there was a decrease of the GCL + IPL thickness in both eyes (Figure A and D), even though her left eye was not affected. During the 15 months of follow-up, the deviation map did not indicate any recovery of the decreased GCL + IPL thickness. Signal strengths of all the Cirrus OCT measurements were 10/10.