human
***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: Developing an evidence base for making public health decisions will require using data from evaluation studies with r and omized and nonr and omized design s. Assessing individual studies and using studies in quantitative research syntheses require transparent reporting of the study , with sufficient detail and clarity to readily see differences and similarities among studies in the same area . The Consoli date d St and ards of Reporting Trials ( CONSORT ) statement provides guidelines for transparent reporting of r and omized clinical trials . We present the initial version of the Transparent Reporting of Evaluations with Nonr and omized Design s ( TREND ) statement . These guidelines emphasize the reporting of theories used and descriptions of intervention and comparison conditions , research design , and methods of adjusting for possible biases in evaluation studies that use nonr and omized design OBJECTIVE Despite recommendations from the Institute of Medicine regarding survivorship care plan ( SCP ) delivery to cancer patients , there have been few health service outcome evaluations thus far . METHODS Gynecologic cancer survivors who were up to one-year post-treatment could participate in an evaluation assessing the health services provided and their perceptions of quality of care . A r and omized , nested , cross-sectional design was used in a large group gynecologic oncology practice . Half ( n=3 ) of the physicians were r and omized to provide and discuss a SCP to patients during a follow-up visit , and the other half did not . Following their visits , all patients were informed that a health service evaluation of the practice was being conducted . Interested patients completed an anonymous 26-item survey assessing administrative , clinical , and educational health services , helpfulness of written material s , and perceptions of quality of care . RESULTS Of the 121 survivors surveyed , 64 received SCPs and 57 were in the no-SCP condition . As a validity check , one question asked about educational material s received during the visit with an expected significant difference noted between conditions ( X(2)=5.513 , p=.019 ; more SCP patients reported receiving material s ) . However , there were no differences between conditions when patients rated health services ( Fs>.37 ) or helpfulness of material s and perceptions of care ( Fs>.19 ) . CONCLUSIONS Gynecologic oncology patients providing ratings of health services and satisfaction with care provided equivalent evaluations , regardless if they had/had not received a SCP from the physician . Thus , the need remains for further evaluations of SCPs if they are to be vehicles for improving health service outcomes There is a need to better measure and improve the quality of oncology care and improve communication with patients and other providers . The American Society of Clinical Oncology Breast Cancer Registry ( BCR ) pilot evaluated the feasibility and acceptability of prospect i ve data collection for quality assessment in daily clinical practice . Data were used to create and share treatment plans/summaries ( TPSs ) at the point of care In 2006 , the IOM released a report citing the importance of “ survivorship plans ” to improve quality of life and care coordination for cancer survivors , but little has been done to evaluate their efficacy . Women with early-stage breast cancer were r and omized within 6 weeks of completing adjuvant therapy to a survivorship intervention group ( SI ) or control group ( CG ) . All subjects were given the NCI publication , “ Facing Forward : Life after Cancer Treatment . ” The SI also met with a nurse/nutritionist to receive a treatment summary , surveillance , and lifestyle recommendations . Both groups completed question naires on the impact of cancer ( IOC ) , patient satisfaction ( FACIT-TS-PS ) , and assessment of survivor concerns ( ASC ) at baseline , 3 and 6 months . Within and between group t tests and linear regression analyses were performed . Among 126 women ( 60 CG , 66 SI ) , mean age was 54 years , 48 % were Hispanic , and the groups were well-balanced by baseline characteristics . No significant differences between the CG and SI on the FACIT-TS-PS or IOC at 3 and 6 months were seen . The ASC health worry subscale was lower ( less worry ) in the SI compared to CG ( p = 0.02 ) . At all time-points , Hispanic women had higher ( worse ) health worry ( p = 0.0008 ) , social-life interference ( p = 0.009 ) , and meaning of cancer scales ( p = 0.0004 ) , and more trust in medical professionals ( p = 0.03 ) compared to non-Hispanic women . While the SI did not lead to significant improvements in most patient-reported outcomes , it was associated with decreased health worry . Future interventions should determine the most efficient and effective method for delivering survivorship care plans BACKGROUND Hodgkin lymphoma ( HL ) survivors face substantially elevated risks of breast cancer and cardiovascular disease . They and their physicians are often unaware of these risks and surveillance recommendations . PROCEDURE A prospect i ve one-arm study was conducted among a r and om sample of 72 HL survivors , ages 27 - 55 years , participating in the Childhood Cancer Survivor Study ( CCSS ) who were at increased risk for breast cancer and /or cardiomyopathy and had not had a screening mammogram or echocardiogram , respectively , within the prior 2 years . A one-page survivorship care plan with recommendations for surveillance was mailed to participants . In addition , survivors ' primary physicians were contacted and provided patient-specific information and a web-based Virtual Information Center was made available for both survivors and physicians . Outcomes were assessed by telephone 6 months after the intervention . RESULTS The survivor participation ( 62/72 ; 86 % ) and 6-month retention ( 56/61 ; 92 % ) rates were high . Tension and anxiety , measured by the Profile of Mood States , did not increase following risk notification ; 91 % of survivors described their reactions to receiving the information in positive terms . At 6 months , 41 % of survivors reported having completed the recommended mammogram ; 20 % reported having an echocardiogram ( females 30 % , males 10 % ) . Only 29 % of survivors visited the website . Nine physicians enrolled , and none used the study re sources . CONCLUSION A mailed , personalized survivorship care plan was effective in communicating risk and increasing compliance with recommended medical surveillance . Internet- and telephone-based strategies to communicate risk were not utilized by survivors or physicians Background : Colorectal cancer ( CRC ) is the most common cancer affecting both men and women in Australia . The illness and related treatments can cause distressing adverse effects , impact on emotional and psychological well-being , and adversely affect social , occupational , and relationship functioning . Current models of follow-up fail to address the complex needs arising after treatment completion . Strategies to better prepare and support survivors are urgently required . Objectives : This study aim ed to develop and pilot test an innovative supportive care program for people with potentially curative CRC . Methods : The SurvivorCare intervention was developed by a multidisciplinary team using 3 key principles : ( 1 ) promote patient involvement and engagement ; ( 2 ) address the specific needs of individual patients , and ( 3 ) use evidence -based strategies to promote well-being and reduce treatment sequelae . It also addressed 4 essential components of survivorship planning , defined by the US Institute of Medicine . Ten survivors completed question naires and satisfaction interviews before and after receiving the intervention . Results : SurvivorCare comprises survivorship educational material s ( booklet , DVD , and question prompt list ) , a tailored survivorship care plan , a tailored nurse-led end-of-treatment consultation , and 3 follow-up telephone calls . Pilot data demonstrated that survivors considered the intervention appropriate , relevant , and useful . Conclusions : SurvivorCare is a well-received , comprehensive intervention that will now be evaluated in a r and omized controlled trial aim ing to reduce distress and unmet needs and improve quality of life in CRC survivors . Implication s for Practice : If SurvivorCare is shown to be effective , it will be possible to quickly and broadly disseminate this model of care 
    Output:
    
agent
***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: Developing an evidence base for making public health decisions will require using data from evaluation studies with r and omized and nonr and omized design s. Assessing individual studies and using studies in quantitative research syntheses require transparent reporting of the study , with sufficient detail and clarity to readily see differences and similarities among studies in the same area . The Consoli date d St and ards of Reporting Trials ( CONSORT ) statement provides guidelines for transparent reporting of r and omized clinical trials . We present the initial version of the Transparent Reporting of Evaluations with Nonr and omized Design s ( TREND ) statement . These guidelines emphasize the reporting of theories used and descriptions of intervention and comparison conditions , research design , and methods of adjusting for possible biases in evaluation studies that use nonr and omized design OBJECTIVE Despite recommendations from the Institute of Medicine regarding survivorship care plan ( SCP ) delivery to cancer patients , there have been few health service outcome evaluations thus far . METHODS Gynecologic cancer survivors who were up to one-year post-treatment could participate in an evaluation assessing the health services provided and their perceptions of quality of care . A r and omized , nested , cross-sectional design was used in a large group gynecologic oncology practice . Half ( n=3 ) of the physicians were r and omized to provide and discuss a SCP to patients during a follow-up visit , and the other half did not . Following their visits , all patients were informed that a health service evaluation of the practice was being conducted . Interested patients completed an anonymous 26-item survey assessing administrative , clinical , and educational health services , helpfulness of written material s , and perceptions of quality of care . RESULTS Of the 121 survivors surveyed , 64 received SCPs and 57 were in the no-SCP condition . As a validity check , one question asked about educational material s received during the visit with an expected significant difference noted between conditions ( X(2)=5.513 , p=.019 ; more SCP patients reported receiving material s ) . However , there were no differences between conditions when patients rated health services ( Fs>.37 ) or helpfulness of material s and perceptions of care ( Fs>.19 ) . CONCLUSIONS Gynecologic oncology patients providing ratings of health services and satisfaction with care provided equivalent evaluations , regardless if they had/had not received a SCP from the physician . Thus , the need remains for further evaluations of SCPs if they are to be vehicles for improving health service outcomes There is a need to better measure and improve the quality of oncology care and improve communication with patients and other providers . The American Society of Clinical Oncology Breast Cancer Registry ( BCR ) pilot evaluated the feasibility and acceptability of prospect i ve data collection for quality assessment in daily clinical practice . Data were used to create and share treatment plans/summaries ( TPSs ) at the point of care In 2006 , the IOM released a report citing the importance of “ survivorship plans ” to improve quality of life and care coordination for cancer survivors , but little has been done to evaluate their efficacy . Women with early-stage breast cancer were r and omized within 6 weeks of completing adjuvant therapy to a survivorship intervention group ( SI ) or control group ( CG ) . All subjects were given the NCI publication , “ Facing Forward : Life after Cancer Treatment . ” The SI also met with a nurse/nutritionist to receive a treatment summary , surveillance , and lifestyle recommendations . Both groups completed question naires on the impact of cancer ( IOC ) , patient satisfaction ( FACIT-TS-PS ) , and assessment of survivor concerns ( ASC ) at baseline , 3 and 6 months . Within and between group t tests and linear regression analyses were performed . Among 126 women ( 60 CG , 66 SI ) , mean age was 54 years , 48 % were Hispanic , and the groups were well-balanced by baseline characteristics . No significant differences between the CG and SI on the FACIT-TS-PS or IOC at 3 and 6 months were seen . The ASC health worry subscale was lower ( less worry ) in the SI compared to CG ( p = 0.02 ) . At all time-points , Hispanic women had higher ( worse ) health worry ( p = 0.0008 ) , social-life interference ( p = 0.009 ) , and meaning of cancer scales ( p = 0.0004 ) , and more trust in medical professionals ( p = 0.03 ) compared to non-Hispanic women . While the SI did not lead to significant improvements in most patient-reported outcomes , it was associated with decreased health worry . Future interventions should determine the most efficient and effective method for delivering survivorship care plans BACKGROUND Hodgkin lymphoma ( HL ) survivors face substantially elevated risks of breast cancer and cardiovascular disease . They and their physicians are often unaware of these risks and surveillance recommendations . PROCEDURE A prospect i ve one-arm study was conducted among a r and om sample of 72 HL survivors , ages 27 - 55 years , participating in the Childhood Cancer Survivor Study ( CCSS ) who were at increased risk for breast cancer and /or cardiomyopathy and had not had a screening mammogram or echocardiogram , respectively , within the prior 2 years . A one-page survivorship care plan with recommendations for surveillance was mailed to participants . In addition , survivors ' primary physicians were contacted and provided patient-specific information and a web-based Virtual Information Center was made available for both survivors and physicians . Outcomes were assessed by telephone 6 months after the intervention . RESULTS The survivor participation ( 62/72 ; 86 % ) and 6-month retention ( 56/61 ; 92 % ) rates were high . Tension and anxiety , measured by the Profile of Mood States , did not increase following risk notification ; 91 % of survivors described their reactions to receiving the information in positive terms . At 6 months , 41 % of survivors reported having completed the recommended mammogram ; 20 % reported having an echocardiogram ( females 30 % , males 10 % ) . Only 29 % of survivors visited the website . Nine physicians enrolled , and none used the study re sources . CONCLUSION A mailed , personalized survivorship care plan was effective in communicating risk and increasing compliance with recommended medical surveillance . Internet- and telephone-based strategies to communicate risk were not utilized by survivors or physicians Background : Colorectal cancer ( CRC ) is the most common cancer affecting both men and women in Australia . The illness and related treatments can cause distressing adverse effects , impact on emotional and psychological well-being , and adversely affect social , occupational , and relationship functioning . Current models of follow-up fail to address the complex needs arising after treatment completion . Strategies to better prepare and support survivors are urgently required . Objectives : This study aim ed to develop and pilot test an innovative supportive care program for people with potentially curative CRC . Methods : The SurvivorCare intervention was developed by a multidisciplinary team using 3 key principles : ( 1 ) promote patient involvement and engagement ; ( 2 ) address the specific needs of individual patients , and ( 3 ) use evidence -based strategies to promote well-being and reduce treatment sequelae . It also addressed 4 essential components of survivorship planning , defined by the US Institute of Medicine . Ten survivors completed question naires and satisfaction interviews before and after receiving the intervention . Results : SurvivorCare comprises survivorship educational material s ( booklet , DVD , and question prompt list ) , a tailored survivorship care plan , a tailored nurse-led end-of-treatment consultation , and 3 follow-up telephone calls . Pilot data demonstrated that survivors considered the intervention appropriate , relevant , and useful . Conclusions : SurvivorCare is a well-received , comprehensive intervention that will now be evaluated in a r and omized controlled trial aim ing to reduce distress and unmet needs and improve quality of life in CRC survivors . Implication s for Practice : If SurvivorCare is shown to be effective , it will be possible to quickly and broadly disseminate this model of care 
    Output:
    