human
***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: Objective : Determine if the online iCare Stress Management e-Training Program reduces stress , bother , depression , and poor life quality for dementia family caregivers ( CGs ) . Method : CGs ( N = 150 ) were r and omly assigned to the iCare Condition ( ICC ) or to the Education/Information-Only Condition ( EOC ) for a 3-month period . Change in self-report measures of stress ( PSS ) ( primary outcome ) , caregiver bother(RMBPC ) , depression ( CES-D ) , and quality of life ( PQOL ) ( secondary outcomes ) was determined , along with usage of new information in one 's own caregiving . Results : A mixed ANOVA revealed that change in perceived stress was significant for the ICC but not the EOC ( p = .017 ) . Changes in the other measures were not significant . More caregivers in the ICC used the material s in their own caregiving situation than those in the EOC . Roughly one-third of the caregivers enrolled in the study dropped prior to completion . Conclusion : Results are promising , but the high dropout is a concern . Future efforts to improve dropout rate and increase participant engagement are warranted . To our knowledge , this is the first attempt to present an evidence -based intervention for CGs via the Internet Background The doubling of the number of people with dementia in the coming decades coupled with the rapid decline in the working population in our graying society is expected to result in a large decrease in the number of professionals available to provide care to people with dementia . As a result , care will be supplied increasingly by untrained informal caregivers and volunteers . To promote effective care and avoid overburdening of untrained and trained caregivers , they must become properly skilled . To this end , the European Skills Training and Reskilling ( STAR ) project , which comprised experts from the domains of education , technology , and dementia care from 6 countries ( the Netherl and s , Sweden , Italy , Malta , Romania , and the United Kingdom ) , worked together to create and evaluate a multilingual e-learning tool . The STAR training portal provides dementia care training both for informal and formal caregivers . Objective The objective of the current study was to evaluate the user friendliness , usefulness , and impact of STAR with informal caregivers , volunteers , and professional caregivers . Methods For 2 to 4 months , the experimental group had access to the STAR training portal , a Web-based portal consisting of 8 modules , 2 of which had a basic level and 6 additional modules at intermediate and advanced levels . The experimental group also had access to online peer and expert communities for support and information exchange . The control group received free access to STAR after the research had ended . The STAR training portal was evaluated in a r and omized controlled trial among informal caregivers and volunteers in addition to professional caregivers ( N=142 ) in the Netherl and s and the United Kingdom . Assessment s were performed with self-assessed , online , st and ardized question naires at baseline and after 2 to 4 months . Primary outcome measures were user friendliness , usefulness , and impact of STAR on knowledge , attitudes , and approaches of caregivers regarding dementia . Secondary outcome measures were empathy , quality of life , burden , and caregivers ’ sense of competence . Results STAR was rated positively by all user groups on both usefulness and user friendliness . Significant effects were found on a person-centered care approach and on the total score on positive attitudes to dementia ; both the experimental and the control group increased in score . Regarding empathy , significant improvements were found in the STAR training group on distress , empathic concern , and taking the perspective of the person with dementia . In the experimental group , however , there was a significant reduction in self-reported sense of competence . Conclusions The STAR training portal is a useful and user-friendly e-learning method , which has demonstrated its ability to provide significant positive effects on caregiver attitudes and empathy BACKGROUND Young Onset Dementia ( YOD ) , defined by first symptoms of cognitive or behavioral decline occurring before the age of 65 years , is relatively rare compared to dementia of later onset , but it is associated with diagnostic difficulty and heavy burden on affected individuals and their informal carers . Existing health and social care structures rarely meet the needs of YOD patients . Internet-based interventions are a novel format of delivering health-related education , counseling , and support to this vulnerable yet underserved group . METHODS The RHAPSODY ( Research to Assess Policies and Strategies for Dementia in the Young ) project is a European initiative to improve care for people with YOD by providing an internet-based information and skill-building program for family carers . The e-learning program focuses on managing problem behaviors , dealing with role change , obtaining support , and looking after oneself . It will be evaluated in a pilot study in three countries using a r and omized unblinded design with a wait-list control group . Participants will be informal carers of people with dementia in Alzheimer 's disease or behavioral-variant Frontotemporal degeneration with an onset before the age of 65 years . The primary outcome will be caregiving self-efficacy after 6 weeks of program use . As secondary outcomes , caregivers ' stress and burden , carer health-related quality of life , caring-related knowledge , patient problem behaviors , and user satisfaction will be assessed . Program utilization will be monitored and a health-economic evaluation will also be performed . CONCLUSIONS The RHAPSODY project will add to the evidence on the potential and limitations of a conveniently accessible , user-friendly , and comprehensive internet-based intervention as an alternative for traditional forms of counseling and support in healthcare , aim ing to optimize care and support for people with YOD and their informal caregivers 
    Output:
    
agent
***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: Objective : Determine if the online iCare Stress Management e-Training Program reduces stress , bother , depression , and poor life quality for dementia family caregivers ( CGs ) . Method : CGs ( N = 150 ) were r and omly assigned to the iCare Condition ( ICC ) or to the Education/Information-Only Condition ( EOC ) for a 3-month period . Change in self-report measures of stress ( PSS ) ( primary outcome ) , caregiver bother(RMBPC ) , depression ( CES-D ) , and quality of life ( PQOL ) ( secondary outcomes ) was determined , along with usage of new information in one 's own caregiving . Results : A mixed ANOVA revealed that change in perceived stress was significant for the ICC but not the EOC ( p = .017 ) . Changes in the other measures were not significant . More caregivers in the ICC used the material s in their own caregiving situation than those in the EOC . Roughly one-third of the caregivers enrolled in the study dropped prior to completion . Conclusion : Results are promising , but the high dropout is a concern . Future efforts to improve dropout rate and increase participant engagement are warranted . To our knowledge , this is the first attempt to present an evidence -based intervention for CGs via the Internet Background The doubling of the number of people with dementia in the coming decades coupled with the rapid decline in the working population in our graying society is expected to result in a large decrease in the number of professionals available to provide care to people with dementia . As a result , care will be supplied increasingly by untrained informal caregivers and volunteers . To promote effective care and avoid overburdening of untrained and trained caregivers , they must become properly skilled . To this end , the European Skills Training and Reskilling ( STAR ) project , which comprised experts from the domains of education , technology , and dementia care from 6 countries ( the Netherl and s , Sweden , Italy , Malta , Romania , and the United Kingdom ) , worked together to create and evaluate a multilingual e-learning tool . The STAR training portal provides dementia care training both for informal and formal caregivers . Objective The objective of the current study was to evaluate the user friendliness , usefulness , and impact of STAR with informal caregivers , volunteers , and professional caregivers . Methods For 2 to 4 months , the experimental group had access to the STAR training portal , a Web-based portal consisting of 8 modules , 2 of which had a basic level and 6 additional modules at intermediate and advanced levels . The experimental group also had access to online peer and expert communities for support and information exchange . The control group received free access to STAR after the research had ended . The STAR training portal was evaluated in a r and omized controlled trial among informal caregivers and volunteers in addition to professional caregivers ( N=142 ) in the Netherl and s and the United Kingdom . Assessment s were performed with self-assessed , online , st and ardized question naires at baseline and after 2 to 4 months . Primary outcome measures were user friendliness , usefulness , and impact of STAR on knowledge , attitudes , and approaches of caregivers regarding dementia . Secondary outcome measures were empathy , quality of life , burden , and caregivers ’ sense of competence . Results STAR was rated positively by all user groups on both usefulness and user friendliness . Significant effects were found on a person-centered care approach and on the total score on positive attitudes to dementia ; both the experimental and the control group increased in score . Regarding empathy , significant improvements were found in the STAR training group on distress , empathic concern , and taking the perspective of the person with dementia . In the experimental group , however , there was a significant reduction in self-reported sense of competence . Conclusions The STAR training portal is a useful and user-friendly e-learning method , which has demonstrated its ability to provide significant positive effects on caregiver attitudes and empathy BACKGROUND Young Onset Dementia ( YOD ) , defined by first symptoms of cognitive or behavioral decline occurring before the age of 65 years , is relatively rare compared to dementia of later onset , but it is associated with diagnostic difficulty and heavy burden on affected individuals and their informal carers . Existing health and social care structures rarely meet the needs of YOD patients . Internet-based interventions are a novel format of delivering health-related education , counseling , and support to this vulnerable yet underserved group . METHODS The RHAPSODY ( Research to Assess Policies and Strategies for Dementia in the Young ) project is a European initiative to improve care for people with YOD by providing an internet-based information and skill-building program for family carers . The e-learning program focuses on managing problem behaviors , dealing with role change , obtaining support , and looking after oneself . It will be evaluated in a pilot study in three countries using a r and omized unblinded design with a wait-list control group . Participants will be informal carers of people with dementia in Alzheimer 's disease or behavioral-variant Frontotemporal degeneration with an onset before the age of 65 years . The primary outcome will be caregiving self-efficacy after 6 weeks of program use . As secondary outcomes , caregivers ' stress and burden , carer health-related quality of life , caring-related knowledge , patient problem behaviors , and user satisfaction will be assessed . Program utilization will be monitored and a health-economic evaluation will also be performed . CONCLUSIONS The RHAPSODY project will add to the evidence on the potential and limitations of a conveniently accessible , user-friendly , and comprehensive internet-based intervention as an alternative for traditional forms of counseling and support in healthcare , aim ing to optimize care and support for people with YOD and their informal caregivers 
    Output:
    