human
***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: This study evaluates the hypothesis that safety-seeking behaviours play an important role in maintaining anxiety because they prevent patients from benefiting from disconfirmatory experience . Patients suffering from panic disorder with agoraphobia carried out a behaviour test , closely followed by an experimental session , which included a brief ( 15 min ) period of exposure during which participants either stopped or maintained within-situation safety-seeking behaviours . When the behaviour test was repeated within two days , patients who had stopped their safety-seeking behaviours during the experimental session showed a significantly greater decrease in catastrophic beliefs and anxiety than those who had maintained safety-seeking behaviour . This difference was also reflected in question naires measuring clinical anxiety . These results are consistent with the cognitive hypothesis Two experiments were conducted to examine the link between safety behaviors and social judgments in  social anxiety disorder ( SAD ) . Safety behaviors were manipulated in the context of a controlled laboratory-based social interaction , and subsequent effects of the manipulation on the social judgments of socially anxious participants ( N = 50 , Study 1 ) and individuals meeting diagnostic criteria for generalized SAD ( N = 80 , Study 2 ) were examined . Participants were r and omly assigned to either a safety behavior reduction plus exposure condition ( SB + EXP ) or a graduated exposure ( EXP ) control condition , and then took part in a conversation with a trained experimental confederate . Results revealed across both studies that participants in the SB + EXP group were less negative and more accurate in judgments of their performance following safety behavior reduction relative to EXP participants . Study 2 also demonstrated that participants in the SB + EXP group displayed lower judgments about the likelihood of negative outcomes in a subsequent social event compared to controls . Moreover , reduction in safety behaviors mediated change in participant self-judgments and future social predictions . The current findings are consistent with cognitive theories of anxiety , and support the causal role of safety behaviors in the persistence of negative social judgments in SAD We examined the effects of safety-seeking behavior and guided threat focus and re appraisal on fear reduction during exposure . Participants ( N=46 ) displaying marked claustrophobic fear were r and omized to one of three 30-min exposure conditions : ( a ) guided threat focus and re appraisal ; ( b ) safety-behavior utilization ; or ( c ) exposure only control . Tripartite outcome assessment s during a behavioral approach test , along with measures of suffocation and restriction fears were obtained at pre- and post-treatment , and at a 2-week follow-up . Treatment process measures were collected throughout treatment and consisted of indices of fear activation ; within and between-trial fear habituation ; and suffocation and entrapment expectancies . Measures of safety behavior utilization and attentional focus were also collected to assess the integrity of the experimental manipulations . Consistent with prediction , those encouraged to utilize safety-behaviors during exposure showed significantly more fear at post-treatment and follow-up relative to those encouraged to focus and reevaluate their core threat(s ) during exposure . Moreover , growth curve analyses of treatment process data analyses revealed that safety-behavior utilization exerted a detrimental effect on between-trial habituation ; whereas guided threat re appraisal enhanced between-trial habituation We tested the efficacy of a unified cognitive-behavioral therapy protocol for anxiety disorders . This group treatment protocol , termed false safety behavior elimination therapy ( F-SET ) , is a cognitive-behavioral approach design ed for use across various anxiety disorders such as panic disorder ( PD ) , social anxiety disorder ( SAD ) , and generalized anxiety disorder ( GAD ) .  F-SET simplifies , as well as broadens , key therapeutic elements of empirically vali date d treatments for anxiety disorders to allow for easier delivery to heterogeneous groups of patients with anxiety psychopathology . Patients with a primary anxiety disorder diagnosis ( N=96 ) were r and omly assigned to F-SET or a wait-list control . Data indicate that F-SET shows good efficacy and durability when delivered to mixed groups of patients with anxieties ( i.e. , PD , SAD , GAD ) by relatively inexperienced clinicians . Findings are discussed in the context of balancing treatment efficacy and clinical utility Background and objectiveS everal cognitive – behavioral factors contribute to the persistence of pain disability in patients with chronic back pain . Fear-avoidance beliefs and fear of movement/(re)injury in particular have been shown to be strong predictors of physical performance and pain disability . Patients reporting substantial pain-related fear might benefit from exposure in vivo to a set of individually tailored , fear-eliciting , and hierarchically ordered physical movements rather than more general grade d activity . Patients and interventions Six consecutive patients with chronic low back pain who reported substantial fear of movement/(re)injury were included in the study . After a no-treatment baseline measurement period , the patients were r and omly assigned to one of two interventions . In the first intervention , patients received exposure in vivo first , followed by grade d activity . In the second intervention , the sequence of treatment modules was reversed . Before each treatment module , treatment credibility was assessed . Daily measures of pain-related fear , pain catastrophizing , and pain intensity were completed using visual analog scales . In addition , st and ardized measures of pain disability , pain-related fear , and pain vigilance were taken before and after each treatment module and at the 1-year follow-up . To obtain more objective data on actual activity levels , an ambulatory activity monitor was carried by the patients during 1 week before and after each treatment module . Results Time series analysis of the daily measures showed that improvements in pain-related fear and pain catastrophizing occurred only during the exposure in vivo and not during the grade d activity , irrespective of the treatment order . Analysis of the pretreatment to post-treatment differences also revealed that decreases in pain-related fear also concurred with decreases in pain disability and pain vigilance and an increase in physical activity levels . All improvements remained at the 1-year follow-up Exposure therapy and cognitive behaviour therapy ( CBT ) are both effective in the treatment of panic disorder with agoraphobia . Cognitive theories suggest that the way in which exposure to avoided situations is implemented in either treatment may be crucial . In particular , it is suggested that clinical improvement will be greatest if opportunities for disconfirmation of feared catastrophes are maximized . In a small pilot study , 16 patients with panic disorder and ( moderate or severe ) agoraphobia were r and omly allocated to either habituation based exposure therapy ( HBET ) or exposure planned as a belief disconfirmation strategy and accompanied by dropping of safety-seeking behaviours . Both treatments were brief ( total of 3.25 h of exposure ) and were similar in terms of expectancy of change . Patients in the CBT condition showed significantly greater improvements in self-report measures of anxiety , panic and situational avoidance . They also completed significantly more steps in a st and ardized behavioural walk , during which they experienced significantly less anxiety . The controlled effect sizes for CBT were substantial ( range 1.7 - 2.7 ) , which suggests it may be a particularly efficient way of managing therapeutic exposure to feared situations in panic disorder with agoraphobia . Further research is needed to clarify the mechanism of change involved The primary aim of the current study was to further investigate the deleterious effects of safety-seeking behaviors on fear reduction by disentangling the effects of perceived availability of threat-relevant safety behaviors during treatment versus their actual use . Participants ( N=72 ) displaying marked claustrophobic fear were r and omly assigned to 1 of 5 conditions : ( a ) exposure only ( EO ) , ( b ) exposure with phobic safety-behavior availability ( SBA ) , ( c ) exposure with safety-behavior utilization ( SBU ) , ( d ) credible placebo treatment ( PL ) , or ( e ) wait list ( WL ) .  High end-state functioning rates at posttreatment were as follows : EO = 94 % , SBA = 45 % , SBU = 44 % , PL = 25 % , and WL = 0 % . Findings suggest that it is the perception of the availability of safety aids as opposed to their actual use that exerts a disruptive effect on fear reduction . Clinical implication s are discussed BACKGROUND AND OBJECTIVES Recent research suggests that safety behaviors ( SB ) may not preclude treatment gains in exposure-based therapy for obsessive-compulsive disorder . However , it is relatively unknown what specific types of SBs may be detrimental to the therapeutic process , with some arguing that SBs be classified based on their function . The current study sought to examine the extent to which different SBs enhanced or weakened symptoms of contamination fear during a single session of exposure . METHODS Sixty-seven non- clinical students were r and omly assigned to one of three conditions : ( 1 ) exposure with no SBs ( NSB ) , ( 2 ) exposure with preventive SBs ( PSB ) , or ( 3 ) exposure with restorative SBs ( RSB ) . RESULTS Among the primary outcome measures , greater reductions in fear and behavioral avoidance were found for RSB in comparison to PSB , and the gains made by RSB were generalizable to other sources of potential contamination . Furthermore , RSB result ed in more rapid reductions in fear and disgust across repeated exposure trials . LIMITATIONS Limitations include the use of a non clinical student sample . CONCLUSIONS Overall , the current study suggests that RSB may be beneficial as an adjunct to therapy whereas PSB are potentially detrimental . Results of the study are discussed in terms of exposure theories and the treatment of anxiety disorders Exposure therapy is traditionally conducted with an emphasis on the elimination of safety behaviors . However , theorists have recently suggested that the judicious use of safety behaviors may improve the tolerability of this treatment without reducing its efficacy . The present study tested this notion by r and omly assigning participants with high claustrophobic fear to receive a single-session intervention with or without access to safety aids during early exposure trials . Improvement was generally equivalent between the treatment conditions , and no reliable benefits or drawbacks were associated with the judicious use of safety behaviors . The theoretical and clinical implication s of these findings are discussed Despite the role afforded interoceptive fear conditioning in etiologic accounts of panic disorder , there are no good experimental demonstrations of such learning in humans . The aim of the present study was to evaluate the interoceptive conditioning account using 20 % carbon dioxide ( CO(2))-enriched air as an interoceptive conditioned stimulus ( CS ) ( i.e. , physiologically inert 5-s exposures ) and unconditioned stimulus ( US ) ( i.e. , physiologically prepotent 15-s exposures ) . Healthy participants ( N=42 ) were r and omly assigned to one of three conditions : a CS-only , contingent CS-US pairings , or unpaired/non-contingent CS and US presentations .  Electrodermal and self-report ( e.g. , distress , fear ) served as indices of conditioned emotional responding . Results showed greater magnitude electrodermal and evaluative fear conditioning in the paired relative to the CS-only condition . The explicitly unpaired condition showed even greater electrodermal and evaluative responding during acquisition , and marked resistance to extinction . The latter results are consistent with the possibility that the unpaired procedure constituted a partial reinforcement procedure in which CO(2 ) onset was paired with more extended CO(2 ) exposure on 50 % of the trials . Overall , the findings are consistent with contemporary learning theory accounts of panic Objective : This study assessed the efficacy of instructions to drop ‘ safety behaviours ’ during exposure tasks in a cognitive-behaviour therapy ( CBT ) group treatment program for social phobia . Method : Fourteen subjects with social phobia received a st and ardised CBT treatment program and were compared to 16 subjects with social phobia  who were given additional instructions to drop safety behaviours . Results : Repeated measures of ANOVA between groups on a specific social phobia measure ( SPAI ) demonstrated significant benefit when instructions to drop safety behaviours were added to the treatment program . Conclusions : The addition of instruction to drop safety behaviours in exposure tasks in the course of CBT treatment for social phobia may be useful . This result supports the cognitive model of social phobia developed by Clark and Wells ( 1995 ) , which postulates that anxiety and negative beliefs about social situations are in part maintained by engaging in safety behaviours . Further replication with larger sample s is required and warranted on the basis of the present study In order to examine the effect of the decreased safety behaviors on social anxiety and negative thoughts and explore the mechanism underlying this effect , this study compared three types of exposure namely , exposure with decreased safety behaviors under cognitive rationale , exposure with decreased safety behaviors under extinction rationale , and exposure with no change in safety behavior .  Forty-five social phobics were r and omly assigned to one of three exposure groups . Results showed that exposure with decreased safety behaviors under cognitive rationale produced significantly greater reductions in anxiety and belief ratings for feared outcomes than exposure with decreased safety behaviors under extinction rationale and exposure with no change in safety behaviors . These results imply that exposure could be more effective if social phobics are encouraged to drop their safety behaviors in the feared social situation , and that the cognitive process of disconfirmation of negative thoughts is the critical element in determining effectiveness of decreased safety behaviors R and omization tests are nonparametric statistical tests that obtain their validity by computationally mimicking the r and om assignment procedure that was used in the design phase of a study . Because r and omization tests do not rely on a r and om sampling assumption , they can provide a better alternative than parametric statistical tests for analyzing data from single-case design s. In this article , an R package is described for use in design ing single-case phase ( AB , ABA , and ABAB ) and alternation ( completely r and omized  ,  alternating treatments  ,  and r and omized block ) experiments , as well as for conducting statistical analyses on data gathered by means of such design s. The R code is presented in a step-by-step way , 
    Output:
    
agent
***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: This study evaluates the hypothesis that safety-seeking behaviours play an important role in maintaining anxiety because they prevent patients from benefiting from disconfirmatory experience . Patients suffering from panic disorder with agoraphobia carried out a behaviour test , closely followed by an experimental session , which included a brief ( 15 min ) period of exposure during which participants either stopped or maintained within-situation safety-seeking behaviours . When the behaviour test was repeated within two days , patients who had stopped their safety-seeking behaviours during the experimental session showed a significantly greater decrease in catastrophic beliefs and anxiety than those who had maintained safety-seeking behaviour . This difference was also reflected in question naires measuring clinical anxiety . These results are consistent with the cognitive hypothesis Two experiments were conducted to examine the link between safety behaviors and social judgments in  social anxiety disorder ( SAD ) . Safety behaviors were manipulated in the context of a controlled laboratory-based social interaction , and subsequent effects of the manipulation on the social judgments of socially anxious participants ( N = 50 , Study 1 ) and individuals meeting diagnostic criteria for generalized SAD ( N = 80 , Study 2 ) were examined . Participants were r and omly assigned to either a safety behavior reduction plus exposure condition ( SB + EXP ) or a graduated exposure ( EXP ) control condition , and then took part in a conversation with a trained experimental confederate . Results revealed across both studies that participants in the SB + EXP group were less negative and more accurate in judgments of their performance following safety behavior reduction relative to EXP participants . Study 2 also demonstrated that participants in the SB + EXP group displayed lower judgments about the likelihood of negative outcomes in a subsequent social event compared to controls . Moreover , reduction in safety behaviors mediated change in participant self-judgments and future social predictions . The current findings are consistent with cognitive theories of anxiety , and support the causal role of safety behaviors in the persistence of negative social judgments in SAD We examined the effects of safety-seeking behavior and guided threat focus and re appraisal on fear reduction during exposure . Participants ( N=46 ) displaying marked claustrophobic fear were r and omized to one of three 30-min exposure conditions : ( a ) guided threat focus and re appraisal ; ( b ) safety-behavior utilization ; or ( c ) exposure only control . Tripartite outcome assessment s during a behavioral approach test , along with measures of suffocation and restriction fears were obtained at pre- and post-treatment , and at a 2-week follow-up . Treatment process measures were collected throughout treatment and consisted of indices of fear activation ; within and between-trial fear habituation ; and suffocation and entrapment expectancies . Measures of safety behavior utilization and attentional focus were also collected to assess the integrity of the experimental manipulations . Consistent with prediction , those encouraged to utilize safety-behaviors during exposure showed significantly more fear at post-treatment and follow-up relative to those encouraged to focus and reevaluate their core threat(s ) during exposure . Moreover , growth curve analyses of treatment process data analyses revealed that safety-behavior utilization exerted a detrimental effect on between-trial habituation ; whereas guided threat re appraisal enhanced between-trial habituation We tested the efficacy of a unified cognitive-behavioral therapy protocol for anxiety disorders . This group treatment protocol , termed false safety behavior elimination therapy ( F-SET ) , is a cognitive-behavioral approach design ed for use across various anxiety disorders such as panic disorder ( PD ) , social anxiety disorder ( SAD ) , and generalized anxiety disorder ( GAD ) .  F-SET simplifies , as well as broadens , key therapeutic elements of empirically vali date d treatments for anxiety disorders to allow for easier delivery to heterogeneous groups of patients with anxiety psychopathology . Patients with a primary anxiety disorder diagnosis ( N=96 ) were r and omly assigned to F-SET or a wait-list control . Data indicate that F-SET shows good efficacy and durability when delivered to mixed groups of patients with anxieties ( i.e. , PD , SAD , GAD ) by relatively inexperienced clinicians . Findings are discussed in the context of balancing treatment efficacy and clinical utility Background and objectiveS everal cognitive – behavioral factors contribute to the persistence of pain disability in patients with chronic back pain . Fear-avoidance beliefs and fear of movement/(re)injury in particular have been shown to be strong predictors of physical performance and pain disability . Patients reporting substantial pain-related fear might benefit from exposure in vivo to a set of individually tailored , fear-eliciting , and hierarchically ordered physical movements rather than more general grade d activity . Patients and interventions Six consecutive patients with chronic low back pain who reported substantial fear of movement/(re)injury were included in the study . After a no-treatment baseline measurement period , the patients were r and omly assigned to one of two interventions . In the first intervention , patients received exposure in vivo first , followed by grade d activity . In the second intervention , the sequence of treatment modules was reversed . Before each treatment module , treatment credibility was assessed . Daily measures of pain-related fear , pain catastrophizing , and pain intensity were completed using visual analog scales . In addition , st and ardized measures of pain disability , pain-related fear , and pain vigilance were taken before and after each treatment module and at the 1-year follow-up . To obtain more objective data on actual activity levels , an ambulatory activity monitor was carried by the patients during 1 week before and after each treatment module . Results Time series analysis of the daily measures showed that improvements in pain-related fear and pain catastrophizing occurred only during the exposure in vivo and not during the grade d activity , irrespective of the treatment order . Analysis of the pretreatment to post-treatment differences also revealed that decreases in pain-related fear also concurred with decreases in pain disability and pain vigilance and an increase in physical activity levels . All improvements remained at the 1-year follow-up Exposure therapy and cognitive behaviour therapy ( CBT ) are both effective in the treatment of panic disorder with agoraphobia . Cognitive theories suggest that the way in which exposure to avoided situations is implemented in either treatment may be crucial . In particular , it is suggested that clinical improvement will be greatest if opportunities for disconfirmation of feared catastrophes are maximized . In a small pilot study , 16 patients with panic disorder and ( moderate or severe ) agoraphobia were r and omly allocated to either habituation based exposure therapy ( HBET ) or exposure planned as a belief disconfirmation strategy and accompanied by dropping of safety-seeking behaviours . Both treatments were brief ( total of 3.25 h of exposure ) and were similar in terms of expectancy of change . Patients in the CBT condition showed significantly greater improvements in self-report measures of anxiety , panic and situational avoidance . They also completed significantly more steps in a st and ardized behavioural walk , during which they experienced significantly less anxiety . The controlled effect sizes for CBT were substantial ( range 1.7 - 2.7 ) , which suggests it may be a particularly efficient way of managing therapeutic exposure to feared situations in panic disorder with agoraphobia . Further research is needed to clarify the mechanism of change involved The primary aim of the current study was to further investigate the deleterious effects of safety-seeking behaviors on fear reduction by disentangling the effects of perceived availability of threat-relevant safety behaviors during treatment versus their actual use . Participants ( N=72 ) displaying marked claustrophobic fear were r and omly assigned to 1 of 5 conditions : ( a ) exposure only ( EO ) , ( b ) exposure with phobic safety-behavior availability ( SBA ) , ( c ) exposure with safety-behavior utilization ( SBU ) , ( d ) credible placebo treatment ( PL ) , or ( e ) wait list ( WL ) .  High end-state functioning rates at posttreatment were as follows : EO = 94 % , SBA = 45 % , SBU = 44 % , PL = 25 % , and WL = 0 % . Findings suggest that it is the perception of the availability of safety aids as opposed to their actual use that exerts a disruptive effect on fear reduction . Clinical implication s are discussed BACKGROUND AND OBJECTIVES Recent research suggests that safety behaviors ( SB ) may not preclude treatment gains in exposure-based therapy for obsessive-compulsive disorder . However , it is relatively unknown what specific types of SBs may be detrimental to the therapeutic process , with some arguing that SBs be classified based on their function . The current study sought to examine the extent to which different SBs enhanced or weakened symptoms of contamination fear during a single session of exposure . METHODS Sixty-seven non- clinical students were r and omly assigned to one of three conditions : ( 1 ) exposure with no SBs ( NSB ) , ( 2 ) exposure with preventive SBs ( PSB ) , or ( 3 ) exposure with restorative SBs ( RSB ) . RESULTS Among the primary outcome measures , greater reductions in fear and behavioral avoidance were found for RSB in comparison to PSB , and the gains made by RSB were generalizable to other sources of potential contamination . Furthermore , RSB result ed in more rapid reductions in fear and disgust across repeated exposure trials . LIMITATIONS Limitations include the use of a non clinical student sample . CONCLUSIONS Overall , the current study suggests that RSB may be beneficial as an adjunct to therapy whereas PSB are potentially detrimental . Results of the study are discussed in terms of exposure theories and the treatment of anxiety disorders Exposure therapy is traditionally conducted with an emphasis on the elimination of safety behaviors . However , theorists have recently suggested that the judicious use of safety behaviors may improve the tolerability of this treatment without reducing its efficacy . The present study tested this notion by r and omly assigning participants with high claustrophobic fear to receive a single-session intervention with or without access to safety aids during early exposure trials . Improvement was generally equivalent between the treatment conditions , and no reliable benefits or drawbacks were associated with the judicious use of safety behaviors . The theoretical and clinical implication s of these findings are discussed Despite the role afforded interoceptive fear conditioning in etiologic accounts of panic disorder , there are no good experimental demonstrations of such learning in humans . The aim of the present study was to evaluate the interoceptive conditioning account using 20 % carbon dioxide ( CO(2))-enriched air as an interoceptive conditioned stimulus ( CS ) ( i.e. , physiologically inert 5-s exposures ) and unconditioned stimulus ( US ) ( i.e. , physiologically prepotent 15-s exposures ) . Healthy participants ( N=42 ) were r and omly assigned to one of three conditions : a CS-only , contingent CS-US pairings , or unpaired/non-contingent CS and US presentations .  Electrodermal and self-report ( e.g. , distress , fear ) served as indices of conditioned emotional responding . Results showed greater magnitude electrodermal and evaluative fear conditioning in the paired relative to the CS-only condition . The explicitly unpaired condition showed even greater electrodermal and evaluative responding during acquisition , and marked resistance to extinction . The latter results are consistent with the possibility that the unpaired procedure constituted a partial reinforcement procedure in which CO(2 ) onset was paired with more extended CO(2 ) exposure on 50 % of the trials . Overall , the findings are consistent with contemporary learning theory accounts of panic Objective : This study assessed the efficacy of instructions to drop ‘ safety behaviours ’ during exposure tasks in a cognitive-behaviour therapy ( CBT ) group treatment program for social phobia . Method : Fourteen subjects with social phobia received a st and ardised CBT treatment program and were compared to 16 subjects with social phobia  who were given additional instructions to drop safety behaviours . Results : Repeated measures of ANOVA between groups on a specific social phobia measure ( SPAI ) demonstrated significant benefit when instructions to drop safety behaviours were added to the treatment program . Conclusions : The addition of instruction to drop safety behaviours in exposure tasks in the course of CBT treatment for social phobia may be useful . This result supports the cognitive model of social phobia developed by Clark and Wells ( 1995 ) , which postulates that anxiety and negative beliefs about social situations are in part maintained by engaging in safety behaviours . Further replication with larger sample s is required and warranted on the basis of the present study In order to examine the effect of the decreased safety behaviors on social anxiety and negative thoughts and explore the mechanism underlying this effect , this study compared three types of exposure namely , exposure with decreased safety behaviors under cognitive rationale , exposure with decreased safety behaviors under extinction rationale , and exposure with no change in safety behavior .  Forty-five social phobics were r and omly assigned to one of three exposure groups . Results showed that exposure with decreased safety behaviors under cognitive rationale produced significantly greater reductions in anxiety and belief ratings for feared outcomes than exposure with decreased safety behaviors under extinction rationale and exposure with no change in safety behaviors . These results imply that exposure could be more effective if social phobics are encouraged to drop their safety behaviors in the feared social situation , and that the cognitive process of disconfirmation of negative thoughts is the critical element in determining effectiveness of decreased safety behaviors R and omization tests are nonparametric statistical tests that obtain their validity by computationally mimicking the r and om assignment procedure that was used in the design phase of a study . Because r and omization tests do not rely on a r and om sampling assumption , they can provide a better alternative than parametric statistical tests for analyzing data from single-case design s. In this article , an R package is described for use in design ing single-case phase ( AB , ABA , and ABAB ) and alternation ( completely r and omized  ,  alternating treatments  ,  and r and omized block ) experiments , as well as for conducting statistical analyses on data gathered by means of such design s. The R code is presented in a step-by-step way , 
    Output:
    