human
***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: Background and Purpose — The Wolf Motor Function Test ( WMFT ) is a new time-based method to evaluate upper extremity performance while providing insight into joint-specific and total limb movements . This study addresses selected psychometric attributes of the WMFT applied to a chronic stroke population . Methods — Nineteen individuals after stroke and with intact cognition and sitting balance were age- and sex-matched with 19 individuals without impairment . Subjects performed the WMFT and the upper extremity portion of the Fugl-Meyer Motor Assessment ( FMA ) on 2 occasions ( 12 to 16 days apart ) , with scoring performed independently by 2 r and om raters . Results — The  WMFT and FMA demonstrated agreement ( P < 0.0001 ) between raters at each session .  WMFT  scores for the dominant and nondominant extremities of individuals without impairment were different ( P ≤0.05 ) from the more and less affected extremities of subjects after stroke . The FMA score for the more affected extremity of subjects after stroke was different ( P ≤0.05 ) from the dominant and nondominant extremities . However , the FMA score for the less affected upper extremity of individuals after stroke was not different ( P > 0.05 ) from the dominant and nondominant extremities of individuals without impairment . The WMFT and FMA scores were related ( P < 0.02 ) for the more affected extremity in individuals after stroke . Conclusions — The interrater reliability , construct validity , and criterion validity of the WMFT , as used in these subject sample s , are supported Objective : Motor recovery after stroke depends on the integrity of ipsilesional motor circuits and interactions between the ipsilesional and contralesional hemispheres . In this sham-controlled r and omized trial , we investigated whether noninvasive modulation of regional excitability of bilateral motor cortices in combination with physical and occupational therapy improves motor outcome after stroke . Methods : Twenty chronic stroke patients were r and omly assigned to receive 5 consecutive sessions of either 1 ) bihemispheric transcranial direct current stimulation ( tDCS ) ( anodal tDCS to upregulate excitability of ipsilesional motor cortex and cathodal tDCS to downregulate excitability of contralesional motor cortex ) with simultaneous physical/occupational therapy or 2 ) sham stimulation with simultaneous physical/occupational therapy .  Changes in motor impairment ( Upper Extremity Fugl-Meyer ) and motor activity ( Wolf Motor Function Test ) assessment s were outcome measures while functional imaging parameters were used to identify neural correlates of motor improvement . Results : The improvement of motor function was significantly greater in the real stimulation group ( 20.7 % in Fugl-Meyer and 19.1 % in Wolf Motor Function Test scores ) when compared to the sham group ( 3.2 % in Fugl-Meyer and 6.0 % in Wolf Motor Function Test scores ) . The effects outlasted the stimulation by at least 1 week . In the real-stimulation group , stronger activation of intact ipsilesional motor regions during paced movements of the affected limb were found postintervention whereas no significant activation changes were seen in the control group . Conclusions : The combination of bihemispheric tDCS and peripheral sensorimotor activities improved motor functions in chronic stroke patients that outlasted the intervention period . This novel approach may potentiate cerebral adaptive processes that facilitate motor recovery after stroke . Classification of evidence : This study provides Class I evidence that for adult patients with ischemic stroke treated at least 5 months after their first and only stroke , bihemispheric tDCS and simultaneous physical/occupational therapy given over 5 consecutive sessions significantly improves motor function as measured by the Upper Extremity Fugl-Meyer assessment ( raw change treated 6.1 ± 3.4 , sham 1.2 ± 1.0 ) BACKGROUND AND PURPOSE To improve the accuracy of early postonset prediction of motor recovery in the flaccid hemiplegic arm , the effects of change in motor function over time on the accuracy of prediction were evaluated , and a prediction model for the probability of regaining dexterity at 6 months was developed . METHODS In 102 stroke patients , dexterity and paresis were measured with the  Action Research Arm Test , Motricity Index , and Fugl-Meyer motor evaluation .  For model development , 23 c and i date determinants were selected . Logistic regression analysis was used for prognostic factors and model development . RESULTS At 6 months , some dexterity in the paretic arm was found in 38 % , and complete functional recovery was seen in 11.6 % of the patients . Total anterior circulation infa rcts , right hemisphere strokes , homonymous hemianopia , visual gaze deficit , visual inattention , and paresis were statistically significant related to a poor arm function . Motricity Index leg scores of at least 25 points in the first week and Fugl-Meyer arm scores of 11 points in the second week increasing to 19 points in the fourth week raised the probability of developing some dexterity ( Action Research Arm Test > or=10 points ) from 74 % ( positive predictive value [ PPV ] , 0.74 ; 95 % confidence interval [ CI ] , 0.63 to 0.86 ) to 94 % ( PPV , 0.83 ; 95 % CI , 0.76 to 0.91 ) at 6 months . No change in probabilities of prediction dexterity was found after 4 weeks . CONCLUSIONS Based on the Fugl-Meyer scores of the flaccid arm , optimal prediction of arm function outcome at 6 months can be made within 4 weeks after onset . Lack of voluntary motor control of the leg in the first week with no emergence of arm synergies at 4 weeks is associated with poor outcome at 6 months Stroke is a leading cause of adult disability and the recovery of motor function is important for independence in activities of daily living . Predicting motor recovery after stroke in individual patients is difficult . Accurate prognosis would enable realistic rehabilitation goal - setting and more efficient allocation of re sources . The aim of this study was to test and refine an algorithm for predicting the potential for recovery of upper limb function after stroke . Forty participants were prospect ively enrolled within 3 days of ischaemic stroke . First ,  shoulder abduction and finger extension strength  were grade d 72 h after stroke onset to compute a shoulder abduction and finger extension score . Secondly , transcranial magnetic stimulation was used to assess the functional integrity of descending motor pathways to the affected upper limb . Third , diffusion-weighted magnetic resonance imaging was used to assess the structural integrity of the posterior limbs of the internal capsules . Finally , these measures were combined in the PREP algorithm for predicting an individual 's potential for upper limb recovery at 12 weeks , measured with the Action Research Arm Test . A cluster analysis was used to independently group patients according to Action Research Arm Test score at 12 weeks , for comparison with predictions from the PREP algorithm . There was excellent correspondence between the cluster analysis of Action Research Arm Test score at 12 weeks and predictions made with the PREP algorithm . The algorithm had positive predictive power of 88 % , negative predictive power of 83 % , specificity of 88 % and sensitivity of 73 % . This study provides preliminary data in support of the PREP algorithm for the prognosis of upper limb recovery in individual patients .  PREP may enable tailored planning of rehabilitation and more accurate stratification of patients in clinical trials PURPOSE EMG-triggered electrostimulation ( EMG-ES ) may improve the motor performance of affected limbs of hemiparetic stroke patients even in the chronic stage . This study was design ed to characterize cortical activation changes following intensified EMG-ES in chronic stroke patients and to identify predictors for successful rehabilitation depending on disease severity . METHODS We studied 9 patients with severe residual hemiparesis , who underwent 8 weeks of daily task-orientated multi-channel EMG-ES of the paretic arm .  Before and after treatment , arm function was evaluated clinical ly and cortical activation patterns were assessed with functional MRI ( fMRI ) and /or transcranial magnetic stimulation ( TMS ) . RESULTS As response to therapy , arm function improved in a subset of patients with more capacity in less affected subjects , but there was no significant gain for those with Box & Block test values below 4 at inception . The clinical improvement , if any , was accompanied by an ipsilesional increase in the sensorimotor cortex ( SMC ) activation area in fMRI and enhanced intracortical facilitation ( ICF ) as revealed by paired TMS . The SMC activation change in fMRI was predicted by the presence or absence of motor-evoked potentials ( MEPs ) on the affected side . CONCLUSIONS The present findings support the notion that intensified EMG-ES may improve the arm function in individual chronic hemiparetic stroke patients but not in more severely impaired individuals . Functional improvements are paralleled by increased ipsilesional SMC activation and enhanced ICF supporting neuroplasticity as contributor to rehabilitation . The clinical score at inception and the presence of MEPs have the best predictive potential OBJECTIVE To examine the intra- and inter-rater reliability of the Action Research Arm Test ( ARAT ) at the item level after stroke . DESIGN An intra-rater and inter-rater reliability study . SUBJECTS Thirty-five participants ( median age 62 years , median time post-stroke 22 months ) with impaired upper extremity function after stroke were included in the study . METHODS Two physiotherapists simultaneously , but independently , assessed the participants ' performance in all 19 items of the ARAT twice in 1 day . A rank-based statistical method for paired ordinal data , including calculation of percentage agreement ( PA ) , systematic disagreements ( relative position ( RP ) , relative concentration ( RC ) ) and individual variability ( relative rank variance ( RV ) ) was used . RESULTS Satisfactory intra-rater and inter-rater agreement was noted for all items except item 19 , which was just below satisfactory level . Within and between raters , small but non-negligible systematic disagreements were found for items 11 , 14 and 19 and for items 1 , 4 , 17 and 19 , respectively . There was no disagreement due to r and om variance within or between raters . CONCLUSION The ARAT is a highly reliable observational rating scale at the item level after stroke . Awareness regarding the small systematic disagreements demonstrated in some items is , however , recommended when using ARAT Background . Motor recovery after stroke is predicted only moderately by clinical variables , implying that there is still a substantial amount of unexplained , biologically meaningful variability in recovery . Regression diagnostics can indicate whether this is associated simply with Gaussian error or instead with multiple sub population s that vary in their relationships to the clinical variables . Objective . To perform regression diagnostics on a linear model for recovery versus clinical predictors . Methods . Forty-one patients with ischemic stroke were studied . Impairment was assessed using the upper extremity Fugl-Meyer Motor Score . Motor recovery was defined as the change in the upper extremity Fugl-Meyer Motor Score from 24 to 72 hours after stroke to 3 or 6 months later . The clinical predictors in the model were age , gender , infa rct location ( subcortical vs cortical ) , diffusion weighted imaging infa rct volume , time to re assessment , and acute upper extremity Fugl-Meyer Motor Score . Regression diagnostics included a Kolmogorov-Smirnov test for Gaussian errors and a test for outliers using Studentized deleted residuals . Results . In the r and om sample , clinical variables explained only 47 % of the variance in recovery . Among the patients with the most severe initial impairment , there was a set of regression outliers who recovered very poorly . With the outliers removed , explained variance in recovery increased to 89 % , and recovery was well approximated by a proportional relationship with initial impairment ( recovery ≅ 0.70 × initial impairment ) . Conclusions . Clinical variables only moderately predict motor recovery . Regression diagnostics demonstrated the existence of a sub population of outliers with severe initial impairment who show little recovery . When these outliers were removed , clinical variables were good predictors of recovery among the remaining patients , showing a tight proportional relationship to initial impairment BACKGROUND We demonstrated that prolonged transcranial magnetic intermittent theta burst stimulation ( iTBS , 1200 pulses/session = iTBS1200 ) produces longer-lasting facilitation in corticospinal excitability than ordinary form of iTBS in healthy subjects . OBJECTIVE Here we show the safety and small-scale efficacy of iTBS1200 over ipsilesional primary motor cortex ( M1 ) in subacute stroke patients . METHODS Twelve patients with first-time , subacute ischemic stroke of the middle cerebral artery were r and omized into two groups that received 10 daily-sessions of either iTBS1200 or sham stimulation ( n=6/group ) over ipsilesional M1 h and region in addition to medical and rehabilitation treatments . The primary outcome measures were safety and tolerability . The secondary outcome measures included the National Institute of Health Stroke Scale ( NIHSS ) , Upper Extremity Fugl-Meyer Test ( UE-FMT ) , Action Research Arm Test ( ARAT ) , active motor thresholds (aMTs)/motor-evoked potentials ( MEPs ) from the extensor carpi radialis ( ECR ) , and magnetoencephalography on post-intervention day 1 and post-stroke day 60 . RESULTS iTBS or sham stimulation was well tolerated by all patients without seizures or significant adverse effects . Compared with the matched controls , the iTBS group showed measurable improvements in the NIHSS and the proximal UE-FMT scores on post-intervention day 1 and post-stroke day 60 . Nevertheless , the h and ARAT scores , aMT and MEPs from the paretic ECR were not different between groups . Post-movement beta synchronization increased over iTBS-conditioned M1 on post-intervention day 1 in testable patients . CONCLUSIONS Repetitive sessions of iTBS1200 over ipsilesional M1 of sub 
    Output:
    
agent
Based on the available evidence , motor evoked potentials at rest were the only biomarker that predicted motor outcome in individuals with severe arm impairment following stroke .
***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: Background and Purpose — The Wolf Motor Function Test ( WMFT ) is a new time-based method to evaluate upper extremity performance while providing insight into joint-specific and total limb movements . This study addresses selected psychometric attributes of the WMFT applied to a chronic stroke population . Methods — Nineteen individuals after stroke and with intact cognition and sitting balance were age- and sex-matched with 19 individuals without impairment . Subjects performed the WMFT and the upper extremity portion of the Fugl-Meyer Motor Assessment ( FMA ) on 2 occasions ( 12 to 16 days apart ) , with scoring performed independently by 2 r and om raters . Results — The  WMFT and FMA demonstrated agreement ( P < 0.0001 ) between raters at each session .  WMFT  scores for the dominant and nondominant extremities of individuals without impairment were different ( P ≤0.05 ) from the more and less affected extremities of subjects after stroke . The FMA score for the more affected extremity of subjects after stroke was different ( P ≤0.05 ) from the dominant and nondominant extremities . However , the FMA score for the less affected upper extremity of individuals after stroke was not different ( P > 0.05 ) from the dominant and nondominant extremities of individuals without impairment . The WMFT and FMA scores were related ( P < 0.02 ) for the more affected extremity in individuals after stroke . Conclusions — The interrater reliability , construct validity , and criterion validity of the WMFT , as used in these subject sample s , are supported Objective : Motor recovery after stroke depends on the integrity of ipsilesional motor circuits and interactions between the ipsilesional and contralesional hemispheres . In this sham-controlled r and omized trial , we investigated whether noninvasive modulation of regional excitability of bilateral motor cortices in combination with physical and occupational therapy improves motor outcome after stroke . Methods : Twenty chronic stroke patients were r and omly assigned to receive 5 consecutive sessions of either 1 ) bihemispheric transcranial direct current stimulation ( tDCS ) ( anodal tDCS to upregulate excitability of ipsilesional motor cortex and cathodal tDCS to downregulate excitability of contralesional motor cortex ) with simultaneous physical/occupational therapy or 2 ) sham stimulation with simultaneous physical/occupational therapy .  Changes in motor impairment ( Upper Extremity Fugl-Meyer ) and motor activity ( Wolf Motor Function Test ) assessment s were outcome measures while functional imaging parameters were used to identify neural correlates of motor improvement . Results : The improvement of motor function was significantly greater in the real stimulation group ( 20.7 % in Fugl-Meyer and 19.1 % in Wolf Motor Function Test scores ) when compared to the sham group ( 3.2 % in Fugl-Meyer and 6.0 % in Wolf Motor Function Test scores ) . The effects outlasted the stimulation by at least 1 week . In the real-stimulation group , stronger activation of intact ipsilesional motor regions during paced movements of the affected limb were found postintervention whereas no significant activation changes were seen in the control group . Conclusions : The combination of bihemispheric tDCS and peripheral sensorimotor activities improved motor functions in chronic stroke patients that outlasted the intervention period . This novel approach may potentiate cerebral adaptive processes that facilitate motor recovery after stroke . Classification of evidence : This study provides Class I evidence that for adult patients with ischemic stroke treated at least 5 months after their first and only stroke , bihemispheric tDCS and simultaneous physical/occupational therapy given over 5 consecutive sessions significantly improves motor function as measured by the Upper Extremity Fugl-Meyer assessment ( raw change treated 6.1 ± 3.4 , sham 1.2 ± 1.0 ) BACKGROUND AND PURPOSE To improve the accuracy of early postonset prediction of motor recovery in the flaccid hemiplegic arm , the effects of change in motor function over time on the accuracy of prediction were evaluated , and a prediction model for the probability of regaining dexterity at 6 months was developed . METHODS In 102 stroke patients , dexterity and paresis were measured with the  Action Research Arm Test , Motricity Index , and Fugl-Meyer motor evaluation .  For model development , 23 c and i date determinants were selected . Logistic regression analysis was used for prognostic factors and model development . RESULTS At 6 months , some dexterity in the paretic arm was found in 38 % , and complete functional recovery was seen in 11.6 % of the patients . Total anterior circulation infa rcts , right hemisphere strokes , homonymous hemianopia , visual gaze deficit , visual inattention , and paresis were statistically significant related to a poor arm function . Motricity Index leg scores of at least 25 points in the first week and Fugl-Meyer arm scores of 11 points in the second week increasing to 19 points in the fourth week raised the probability of developing some dexterity ( Action Research Arm Test > or=10 points ) from 74 % ( positive predictive value [ PPV ] , 0.74 ; 95 % confidence interval [ CI ] , 0.63 to 0.86 ) to 94 % ( PPV , 0.83 ; 95 % CI , 0.76 to 0.91 ) at 6 months . No change in probabilities of prediction dexterity was found after 4 weeks . CONCLUSIONS Based on the Fugl-Meyer scores of the flaccid arm , optimal prediction of arm function outcome at 6 months can be made within 4 weeks after onset . Lack of voluntary motor control of the leg in the first week with no emergence of arm synergies at 4 weeks is associated with poor outcome at 6 months Stroke is a leading cause of adult disability and the recovery of motor function is important for independence in activities of daily living . Predicting motor recovery after stroke in individual patients is difficult . Accurate prognosis would enable realistic rehabilitation goal - setting and more efficient allocation of re sources . The aim of this study was to test and refine an algorithm for predicting the potential for recovery of upper limb function after stroke . Forty participants were prospect ively enrolled within 3 days of ischaemic stroke . First ,  shoulder abduction and finger extension strength  were grade d 72 h after stroke onset to compute a shoulder abduction and finger extension score . Secondly , transcranial magnetic stimulation was used to assess the functional integrity of descending motor pathways to the affected upper limb . Third , diffusion-weighted magnetic resonance imaging was used to assess the structural integrity of the posterior limbs of the internal capsules . Finally , these measures were combined in the PREP algorithm for predicting an individual 's potential for upper limb recovery at 12 weeks , measured with the Action Research Arm Test . A cluster analysis was used to independently group patients according to Action Research Arm Test score at 12 weeks , for comparison with predictions from the PREP algorithm . There was excellent correspondence between the cluster analysis of Action Research Arm Test score at 12 weeks and predictions made with the PREP algorithm . The algorithm had positive predictive power of 88 % , negative predictive power of 83 % , specificity of 88 % and sensitivity of 73 % . This study provides preliminary data in support of the PREP algorithm for the prognosis of upper limb recovery in individual patients .  PREP may enable tailored planning of rehabilitation and more accurate stratification of patients in clinical trials PURPOSE EMG-triggered electrostimulation ( EMG-ES ) may improve the motor performance of affected limbs of hemiparetic stroke patients even in the chronic stage . This study was design ed to characterize cortical activation changes following intensified EMG-ES in chronic stroke patients and to identify predictors for successful rehabilitation depending on disease severity . METHODS We studied 9 patients with severe residual hemiparesis , who underwent 8 weeks of daily task-orientated multi-channel EMG-ES of the paretic arm .  Before and after treatment , arm function was evaluated clinical ly and cortical activation patterns were assessed with functional MRI ( fMRI ) and /or transcranial magnetic stimulation ( TMS ) . RESULTS As response to therapy , arm function improved in a subset of patients with more capacity in less affected subjects , but there was no significant gain for those with Box & Block test values below 4 at inception . The clinical improvement , if any , was accompanied by an ipsilesional increase in the sensorimotor cortex ( SMC ) activation area in fMRI and enhanced intracortical facilitation ( ICF ) as revealed by paired TMS . The SMC activation change in fMRI was predicted by the presence or absence of motor-evoked potentials ( MEPs ) on the affected side . CONCLUSIONS The present findings support the notion that intensified EMG-ES may improve the arm function in individual chronic hemiparetic stroke patients but not in more severely impaired individuals . Functional improvements are paralleled by increased ipsilesional SMC activation and enhanced ICF supporting neuroplasticity as contributor to rehabilitation . The clinical score at inception and the presence of MEPs have the best predictive potential OBJECTIVE To examine the intra- and inter-rater reliability of the Action Research Arm Test ( ARAT ) at the item level after stroke . DESIGN An intra-rater and inter-rater reliability study . SUBJECTS Thirty-five participants ( median age 62 years , median time post-stroke 22 months ) with impaired upper extremity function after stroke were included in the study . METHODS Two physiotherapists simultaneously , but independently , assessed the participants ' performance in all 19 items of the ARAT twice in 1 day . A rank-based statistical method for paired ordinal data , including calculation of percentage agreement ( PA ) , systematic disagreements ( relative position ( RP ) , relative concentration ( RC ) ) and individual variability ( relative rank variance ( RV ) ) was used . RESULTS Satisfactory intra-rater and inter-rater agreement was noted for all items except item 19 , which was just below satisfactory level . Within and between raters , small but non-negligible systematic disagreements were found for items 11 , 14 and 19 and for items 1 , 4 , 17 and 19 , respectively . There was no disagreement due to r and om variance within or between raters . CONCLUSION The ARAT is a highly reliable observational rating scale at the item level after stroke . Awareness regarding the small systematic disagreements demonstrated in some items is , however , recommended when using ARAT Background . Motor recovery after stroke is predicted only moderately by clinical variables , implying that there is still a substantial amount of unexplained , biologically meaningful variability in recovery . Regression diagnostics can indicate whether this is associated simply with Gaussian error or instead with multiple sub population s that vary in their relationships to the clinical variables . Objective . To perform regression diagnostics on a linear model for recovery versus clinical predictors . Methods . Forty-one patients with ischemic stroke were studied . Impairment was assessed using the upper extremity Fugl-Meyer Motor Score . Motor recovery was defined as the change in the upper extremity Fugl-Meyer Motor Score from 24 to 72 hours after stroke to 3 or 6 months later . The clinical predictors in the model were age , gender , infa rct location ( subcortical vs cortical ) , diffusion weighted imaging infa rct volume , time to re assessment , and acute upper extremity Fugl-Meyer Motor Score . Regression diagnostics included a Kolmogorov-Smirnov test for Gaussian errors and a test for outliers using Studentized deleted residuals . Results . In the r and om sample , clinical variables explained only 47 % of the variance in recovery . Among the patients with the most severe initial impairment , there was a set of regression outliers who recovered very poorly . With the outliers removed , explained variance in recovery increased to 89 % , and recovery was well approximated by a proportional relationship with initial impairment ( recovery ≅ 0.70 × initial impairment ) . Conclusions . Clinical variables only moderately predict motor recovery . Regression diagnostics demonstrated the existence of a sub population of outliers with severe initial impairment who show little recovery . When these outliers were removed , clinical variables were good predictors of recovery among the remaining patients , showing a tight proportional relationship to initial impairment BACKGROUND We demonstrated that prolonged transcranial magnetic intermittent theta burst stimulation ( iTBS , 1200 pulses/session = iTBS1200 ) produces longer-lasting facilitation in corticospinal excitability than ordinary form of iTBS in healthy subjects . OBJECTIVE Here we show the safety and small-scale efficacy of iTBS1200 over ipsilesional primary motor cortex ( M1 ) in subacute stroke patients . METHODS Twelve patients with first-time , subacute ischemic stroke of the middle cerebral artery were r and omized into two groups that received 10 daily-sessions of either iTBS1200 or sham stimulation ( n=6/group ) over ipsilesional M1 h and region in addition to medical and rehabilitation treatments . The primary outcome measures were safety and tolerability . The secondary outcome measures included the National Institute of Health Stroke Scale ( NIHSS ) , Upper Extremity Fugl-Meyer Test ( UE-FMT ) , Action Research Arm Test ( ARAT ) , active motor thresholds (aMTs)/motor-evoked potentials ( MEPs ) from the extensor carpi radialis ( ECR ) , and magnetoencephalography on post-intervention day 1 and post-stroke day 60 . RESULTS iTBS or sham stimulation was well tolerated by all patients without seizures or significant adverse effects . Compared with the matched controls , the iTBS group showed measurable improvements in the NIHSS and the proximal UE-FMT scores on post-intervention day 1 and post-stroke day 60 . Nevertheless , the h and ARAT scores , aMT and MEPs from the paretic ECR were not different between groups . Post-movement beta synchronization increased over iTBS-conditioned M1 on post-intervention day 1 in testable patients . CONCLUSIONS Repetitive sessions of iTBS1200 over ipsilesional M1 of sub 
    Output:
    