human
***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: INTRODUCTION : Pulpectomy of primary teeth is commonly carried out with h and files and broaches ; a tricky and time consuming procedure . The purpose of this in vitro study was to compare the cleaning efficacy and time taken for instrumentation of deciduous molars using h and K-files and Flex Master rotary system . MATERIAL S AND METHODS : In this study , 68 canals of 23 extracted primary molars with at least two third intact roots and 7 - 12 mm length were selected . After preparing an access cavity , K-file size # 15 was introduced into the root canal and India ink was injected with an insulin syringe . Sixty sample s were r and omly divided in to experimental groups in group I ( n=30 ) , root canals were prepared with h and K-files ; in group II ( n=30 ) , rotary Flex Master files were used for instrumentation , and in group III 8 remained sample s were considered as negative controls . After clearing and root sectioning , the removal of India ink from cervical , middle , and apical thirds was scored . Data was analyzed using student 's T-test and Mann-Whitney U test . RESULTS : There was no significant difference between experimental groups cleaning efficacy at the cervical , middle and apical root canal thirds . Only the coronal third scored higher in the h and instrumented group ( P<0.001 ) . Instrumentation with Flex Master rotary files was significantly less time consuming ( P<0.001 ) . CONCLUSION : Although there was no difference in cleanliness efficacy at the apical and middle thirds , the coronal third was more effectively cleaned with h and files . Predictably , time efficiency was a significant advantage with rotary technique Background : Root canal cleaning is an important step in endodontic therapy . In order to develop better techniques , a new generation of endodontic instruments has been design ed . The aim of this study was to compare the effectiveness of manual K-files ( Mani Co , Tokyo , Japan ) and two rotary systems – Mtwo ( Dentsply-Maillefer , Ballaigues , Switzerl and ) and ProTaper ( VDW , Munich , Germany)–for root canal preparation in primary molars . Material s and Methods : India ink was injected to 160 mesiobuccal and distal root canals of m and ibular primary molars . The teeth were r and omly divided into three experimental groups and one control group . In each experimental group , either manual instruments ( K-files ) or rotary instruments ( Mtwo or ProTaper ) were used to prepare root canals . After cleaning the canals and clearing the teeth , ink removal was evaluated with a stereomicroscope . Statistical analysis was done with Kruskal – Wallis and Friedman tests . Results : There were no significant differences in cleaning efficiency between manual and rotary instruments . Only ProTaper files performed significantly better in the coronal and middle thirds than in the apical third of the root canal . Conclusion : Manual K-files and the Mtwo and ProTaper rotary systems showed equally acceptable cleaning ability in primary molar root canals Background . Efficient canal preparation is the key to successful root canal treatment . This study aim ed to assess the cleaning and shaping ability , preparation time and file deformation of rotary , reciprocating and manual instrumentation in canal preparation of primary molars . Methods . The mesiobuccal canals of 64 extracted primary m and ibular second molars were injected with India ink . The sample s were r and omly divided into one control and three experimental groups . Experimental groups were instrumented with K-file , Mtwo in continuous rotation and Reciproc in reciprocating motion , respectively . The control group received no treatment . The files were discarded after four applications . Shaping ability was evaluated using CBCT . After clearing , ink removal was scored . Preparation time and file fracture or deformation was also recorded . Data were analyzed with SPSS 19 using chi-squared , Fisher ’s exact test , Kruskal-Wallis and post hoc tests at a significance level of 0.05 . Results . Considering cleanliness , at coronal third Reciproc was better than K-file ( P < 0.001 ) , but not more effective than Mtwo ( P = 0.080 ) . Furthermore , Mtwo leaved the canal cleaner than K-file ( P = 0.001 ) . In the middle third , only Reciproc exhibited better cleaning efficacy than K-file ( P = 0.005 ) . In the apical third , no difference was detected between the groups ( P = 0.794 ) . Regarding shaping ability , no differences were found between Reciproc and Mtwo ( P = 1.00 ) . Meanwhile , both displayed better shaping efficacy than K-file ( P < 0.05 ) . Between each two groups , there were differences in preparation time ( P < 0.05 ) , with Reciproc being the fastest . No file failure occurred . Conclusion . Fast and sufficient cleaning and shaping could be achieved with Mtwo and especially with Reciproc OBJECTIVES The aims of this study were to evaluate iodoform base material s for root canal treatment of necrotic primary teeth , and to compare them with traditionally used zinc oxide and eugenol ( ZOE ) . SAMPLE AND METHODS Zinc oxide and eugenol and Vitapex ( a premixed calcium hydroxide and iodoform paste ) were compared for root canal treatment in 52 necrotic primary teeth in two groups of children with a mean age of 5 years and 8.4 months . All the patients were followed-up clinical ly and radiographically 3 months and 10 - 16 months postoperatively . RESULTS The overall success rates of Vitapex and ZOE were 100 % and 78.5 % , respectively . Using Fisher 's Exact Test , the difference was statistically significant ( P < 0.05 ) . CONCLUSION Both ZOE and Vitapex gave encouraging results .  Vitapex , however , can be used more safely whenever there is a doubt about the patient 's return for follow-up AIM To compare and evaluate the volumetric analysis of pre- and post-root canal instrumentation in primary teeth using h and and rotary files and also to analyse the volume of root canal filling . MATERIAL S AND METHODS A total of 20 primary teeth were divided into two groups r and omly and subjected to spiral computed tomography ( SCT ) analysis before and after instrumentation . For manual technique ( Group 1 ) , teeth were prepared using K files and rotary ( Group 2 ) preparation was performed with Mtwo files .  Volumetric enlargement was calculated using Osirix software . Root canals were then filled with rotary lentulospiral using zinc oxide-eugenol cement ( ZOE ) . The filled volume in each canal was measured using SCT and the percentage of obturated volume was calculated . The data were statistically analysed using paired t-tests . RESULTS There was a statistically significant difference in the volume of root canal enlarged in both the groups . Rotary files showed significant increase in the volume compared to K files . Mtwo instrumented root canals showed good obturated volume compared to manual technique , although voids were common in both the groups . CONCLUSION Rotary root canal instrumentation may be indicated for utilization in primary teeth , for enhancing root canal preparation and good quality of root canal filling 
    Output:
    
agent
Conclusion Rotary instrumentation shows equivalent cleaning efficiency than h and files depending on the system of instrumentation and techniques used .
However , use of rotary in primary teeth leads to improved shaping of canals providing better quality of treatment in less time .
***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: INTRODUCTION : Pulpectomy of primary teeth is commonly carried out with h and files and broaches ; a tricky and time consuming procedure . The purpose of this in vitro study was to compare the cleaning efficacy and time taken for instrumentation of deciduous molars using h and K-files and Flex Master rotary system . MATERIAL S AND METHODS : In this study , 68 canals of 23 extracted primary molars with at least two third intact roots and 7 - 12 mm length were selected . After preparing an access cavity , K-file size # 15 was introduced into the root canal and India ink was injected with an insulin syringe . Sixty sample s were r and omly divided in to experimental groups in group I ( n=30 ) , root canals were prepared with h and K-files ; in group II ( n=30 ) , rotary Flex Master files were used for instrumentation , and in group III 8 remained sample s were considered as negative controls . After clearing and root sectioning , the removal of India ink from cervical , middle , and apical thirds was scored . Data was analyzed using student 's T-test and Mann-Whitney U test . RESULTS : There was no significant difference between experimental groups cleaning efficacy at the cervical , middle and apical root canal thirds . Only the coronal third scored higher in the h and instrumented group ( P<0.001 ) . Instrumentation with Flex Master rotary files was significantly less time consuming ( P<0.001 ) . CONCLUSION : Although there was no difference in cleanliness efficacy at the apical and middle thirds , the coronal third was more effectively cleaned with h and files . Predictably , time efficiency was a significant advantage with rotary technique Background : Root canal cleaning is an important step in endodontic therapy . In order to develop better techniques , a new generation of endodontic instruments has been design ed . The aim of this study was to compare the effectiveness of manual K-files ( Mani Co , Tokyo , Japan ) and two rotary systems – Mtwo ( Dentsply-Maillefer , Ballaigues , Switzerl and ) and ProTaper ( VDW , Munich , Germany)–for root canal preparation in primary molars . Material s and Methods : India ink was injected to 160 mesiobuccal and distal root canals of m and ibular primary molars . The teeth were r and omly divided into three experimental groups and one control group . In each experimental group , either manual instruments ( K-files ) or rotary instruments ( Mtwo or ProTaper ) were used to prepare root canals . After cleaning the canals and clearing the teeth , ink removal was evaluated with a stereomicroscope . Statistical analysis was done with Kruskal – Wallis and Friedman tests . Results : There were no significant differences in cleaning efficiency between manual and rotary instruments . Only ProTaper files performed significantly better in the coronal and middle thirds than in the apical third of the root canal . Conclusion : Manual K-files and the Mtwo and ProTaper rotary systems showed equally acceptable cleaning ability in primary molar root canals Background . Efficient canal preparation is the key to successful root canal treatment . This study aim ed to assess the cleaning and shaping ability , preparation time and file deformation of rotary , reciprocating and manual instrumentation in canal preparation of primary molars . Methods . The mesiobuccal canals of 64 extracted primary m and ibular second molars were injected with India ink . The sample s were r and omly divided into one control and three experimental groups . Experimental groups were instrumented with K-file , Mtwo in continuous rotation and Reciproc in reciprocating motion , respectively . The control group received no treatment . The files were discarded after four applications . Shaping ability was evaluated using CBCT . After clearing , ink removal was scored . Preparation time and file fracture or deformation was also recorded . Data were analyzed with SPSS 19 using chi-squared , Fisher ’s exact test , Kruskal-Wallis and post hoc tests at a significance level of 0.05 . Results . Considering cleanliness , at coronal third Reciproc was better than K-file ( P < 0.001 ) , but not more effective than Mtwo ( P = 0.080 ) . Furthermore , Mtwo leaved the canal cleaner than K-file ( P = 0.001 ) . In the middle third , only Reciproc exhibited better cleaning efficacy than K-file ( P = 0.005 ) . In the apical third , no difference was detected between the groups ( P = 0.794 ) . Regarding shaping ability , no differences were found between Reciproc and Mtwo ( P = 1.00 ) . Meanwhile , both displayed better shaping efficacy than K-file ( P < 0.05 ) . Between each two groups , there were differences in preparation time ( P < 0.05 ) , with Reciproc being the fastest . No file failure occurred . Conclusion . Fast and sufficient cleaning and shaping could be achieved with Mtwo and especially with Reciproc OBJECTIVES The aims of this study were to evaluate iodoform base material s for root canal treatment of necrotic primary teeth , and to compare them with traditionally used zinc oxide and eugenol ( ZOE ) . SAMPLE AND METHODS Zinc oxide and eugenol and Vitapex ( a premixed calcium hydroxide and iodoform paste ) were compared for root canal treatment in 52 necrotic primary teeth in two groups of children with a mean age of 5 years and 8.4 months . All the patients were followed-up clinical ly and radiographically 3 months and 10 - 16 months postoperatively . RESULTS The overall success rates of Vitapex and ZOE were 100 % and 78.5 % , respectively . Using Fisher 's Exact Test , the difference was statistically significant ( P < 0.05 ) . CONCLUSION Both ZOE and Vitapex gave encouraging results .  Vitapex , however , can be used more safely whenever there is a doubt about the patient 's return for follow-up AIM To compare and evaluate the volumetric analysis of pre- and post-root canal instrumentation in primary teeth using h and and rotary files and also to analyse the volume of root canal filling . MATERIAL S AND METHODS A total of 20 primary teeth were divided into two groups r and omly and subjected to spiral computed tomography ( SCT ) analysis before and after instrumentation . For manual technique ( Group 1 ) , teeth were prepared using K files and rotary ( Group 2 ) preparation was performed with Mtwo files .  Volumetric enlargement was calculated using Osirix software . Root canals were then filled with rotary lentulospiral using zinc oxide-eugenol cement ( ZOE ) . The filled volume in each canal was measured using SCT and the percentage of obturated volume was calculated . The data were statistically analysed using paired t-tests . RESULTS There was a statistically significant difference in the volume of root canal enlarged in both the groups . Rotary files showed significant increase in the volume compared to K files . Mtwo instrumented root canals showed good obturated volume compared to manual technique , although voids were common in both the groups . CONCLUSION Rotary root canal instrumentation may be indicated for utilization in primary teeth , for enhancing root canal preparation and good quality of root canal filling 
    Output:
    