human
***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: OBJECTIVE To analyze socioeconomic indicators , physical activity ( PA ) opportunities , and behavioral correlates of cardiorespiratory and muscular fitness among Brazilian boys and girls . METHODS A sample of 1555 adolescents was r and omly selected . Age- and sex-specific st and ard scores were calculated for each fitness component . RESULTS Among boys , head of household 's schooling , involvement in organized PA , meeting the PA recommendations , and computer/games use were associated with cardiorespiratory fitness . Involvement in organized PA and active time in Physical Education ( PE ) classes were predictors of muscular fitness . Among girls , active time in PE classes and TV watching were predictors of cardiorespiratory fitness . Meeting the PA recommendations was associated with muscular fitness . CONCLUSION PA variables and sedentary behaviors should be independently considered for physical fitness promotion in youth Overwhelming evidence shows the quality of reporting of r and omised controlled trials ( RCTs ) is not optimal . Without transparent reporting , readers can not judge the reliability and validity of trial findings nor extract information for systematic review s. Recent method ological analyses indicate that inadequate reporting and design are associated with biased estimates of treatment effects . Such systematic error is seriously damaging to RCTs , which are considered the gold st and ard for evaluating interventions because of their ability to minimise or avoid bias . A group of scientists and editors developed the CONSORT ( Consoli date d St and ards of Reporting Trials ) statement to improve the quality of reporting of RCTs . It was first published in 1996 and up date d in 2001 . The statement consists of a checklist and flow diagram that authors can use for reporting an RCT . Many leading medical journals and major international editorial groups have endorsed the CONSORT statement . The statement facilitates critical appraisal and interpretation of RCTs . During the 2001 CONSORT revision , it became clear that explanation and elaboration of the principles underlying the CONSORT statement would help investigators and others to write or appraise trial reports . A CONSORT explanation and elaboration article was published in 2001 alongside the 2001 version of the CONSORT statement . After an expert meeting in January 2007 , the CONSORT statement has been further revised and is published as the CONSORT 2010 Statement . This up date improves the wording and clarity of the previous checklist and incorporates recommendations related to topics that have only recently received recognition , such as selective outcome reporting bias . This explanatory and elaboration document-intended to enhance the use , underst and ing , and dissemination of the CONSORT statement-has also been extensively revised . It presents the meaning and rationale for each new and up date d checklist item providing examples of good reporting and , where possible , references to relevant empirical studies . Several examples of flow diagrams are included . The CONSORT 2010 Statement , this revised explanatory and elaboration document , and the associated website ( www.consort-statement.org ) should be helpful re sources to improve reporting of r and omised trials Aims : To investigate how physical activity , physical performance and sociodemographic characteristics at the age of 16 are related to adult health habits ( physical activity , dietary intake , smoking ) and biological risk factors for cardiovascular diseases ( being overweight , low aerobic fitness , unfavorable levels of serum lipids , high blood pressure ) . Methods : A r and omly selected group of 220 male and 205 female students at 16 years of age was tested in 1974 , and reinvestigated 18 years later . Results : The predictive health profiles for adult lifestyle and biological risk factors were different in men and women . Leisure sports activity along with high performance in the nine-minute run among the boys and in the two-h and lift test among the girls were significant predictors of adult physical activity . A positive attitude to aerobic exercise  and high performance in the nine-minute run test among the boys and high marks in physical education among the girls decreased the risk of smoking .  Leisure sports activities together with body mass index at young ages were the most powerful predictors of adult biological risk factors , but attitudes to sports and educational level were also significant determinants . Conclusion : These results contribute to the knowledge of which factors at young ages may promote adult healthy habits in particular physical activities BACKGROUND Rural children are at a particular high risk for obesity . Given the importance of exercise in obesity and chronic disease prevention , this study evaluated the level and relationship between physical activity and fitness in a sample of rural third grade rs . The second purpose of the study was to determine potential differences in physical activity and fitness level by weight status in this sample . METHODS Twelve schools participating in a multidisciplinary research project were r and omly selected for the study . Body mass index-for-age percentile , the modified Self-administered Physical Activity Checklist  , and the FITNESSGRAM battery tests were utilized to determine children 's weight status , physical activity , and fitness level , respectively . RESULTS Thirty-eight percent of the 237 participating children ( 9.2 ± 0.4 years ) were overweight or obese . Nearly 15 % were extremely obese . Children spent 91.8 ± 83.8 and 32.2 ± 47.7 minutes in moderate- and vigorous-intensity activities . Obese children spent less time in moderate-intensity activity ( p < .01 ) and combined moderate- and vigorous-intensity activity more than other children ( p < .05 ) . Forty-three percent of all children failed to meet the fitness st and ard for muscular strength and 36 % failed to meet it for flexibility . CONCLUSIONS Rural children in this sample had higher rates of obesity compared to the national average ; they had poor fitness and 30 % failed to meet the minimum physical activity recommendations on the previous day . Future interventions should focus on increasing physical activity , especially of moderate-intensity , and improving physical fitness in order to reduce obesity and decrease the risk of future chronic diseases in this high-risk population BACKGROUND Childhood obesity has been inconsistently associated with decreased levels of physical activity and fitness . Moreover , little is known about this relationship among Filipino preteens . METHODS This cross sectional study reports the association between childhood obesity , measures of physical activity , and fitness .  Children aged 11 to 12 from r and omly selected schools from San Juan , Metromanila were included . Outcome measures were body mass index , Filipino modified Physical Activity Question naire for Older children ( F_PAQ-C ) ,  st and ing broad jump , 50 m sprint  and  20 m multistage shuttle run .  RESULTS 380 children participated in the study . Obese children had significantly lower median scores in the F_PAQ-C compared with overweight children . Overweight children had lower scores in the st and ing broad jump , 50 m sprints and predicted VO2max as compared with children with normal BMI . There were modest associations between the 50 m sprint , predicted VO2max , and F_PAQ-C. CONCLUSION Our study has showed that physical activity and fitness scores were strongly correlated with childhood obesity . If childhood physical fitness is a predictor of physical fitness in adulthood which is a risk factor in cardiovascular diseases , there is a strong possibility that the prevalence of cardiovascular disease in the Philippines will increase dramatically in the future The aims of this study were to investigate whether  physical activity ( PA ) and sedentary time ( ST )  in 9- and 15-year-olds differed between 2005 - 2006 and 2011 - 2012 ( secular change ) , and to investigate changes in PA and ST from age 9 to 15 ( longitudinal change ) . In 2005 - 2006 , we invited nationally representative sample s of Norwegian 9- ( n=1470 ) and 15-year-olds ( n=1348 ) to participate . In 2011 - 2012 , we invited a new nationally representative sample of 9-year-olds ( n=1945 ) , whereas 15-year-olds ( n=1759 ) were invited to participate either based on previous participation in 2005 - 2006 or from a r and om sample of schools . We assessed PA and ST objective ly using accelerometers . In 2011 - 2012 , both 9- and 15-year-olds spent more time sedentary ( ≥35.7 min/d , P<.001 ) and less time in light PA ( ≥35.2 min/d , P<.001 ) compared to their peers in 2005 - 2006 . Nine-year-old girls also spent less time in moderate-to-vigorous PA ( MVPA ) ( 4.2 min/d , P=.041 ) . In both age groups , the proportion accumulating an average of 60 min/d of MVPA did not differ between the two cohorts . From age 9 to 15 , girls and boys decreased their time spent in LPA ( ≥106.7 min/d , P<.001 ) and in MVPA ( ≥20.8 min/d , P<.001 ) . During the same period , ST increased by a mean of > 2 h/d ( P<.011 ) . We observed an adverse secular change in PA from 2005 - 2006 to 2011 - 2012 among 9- and 15-year-olds , and a large decline in PA in the participants followed longitudinally from age 9 to 15 years Objective To investigate the associations between body composition , cardiorespiratory and muscular fitness in relation to travel mode to school in children and adolescents . Method Children and adolescents from 40 elementary schools and 23 high schools representing all regions in Norway were invited to participate in the study . Anthropometry , cardiorespiratory and muscular fitness  were tested at the school location . Question naires were used in order to register mode of transport to school , age , gender and levels of leisure time physical activity . Results A total of 1694 ( i.e. 60 % of all invited participants ) children and adolescents at a mean age of 9.6 and 15.6 respectively ( SD = 0.4 for both groups ) were analyzed for associations with physical fitness variables . Males cycling to school had lower sum of skin folds than adolescents walking to school . Higher cardiorespiratory fitness in adolescents and male cyclists compared to walkers and passive commuters were observed . Among children , cycling and walking to school , higher isometric muscle endurance in the back extensors compared to passive commuters was observed . Conclusion Based on this national representative cross-sectional examination of r and omly selected children and adolescents there is evidence that active commuting , especially cycling , is associated with a favourable body composition and better cardiorespiratory and muscular fitness as compared to passive commuting OBJECTIVE To test the hypothesis that resistance training may increase spontaneous physical activity in children . STUDY DESIGN Two junior ice hockey teams were r and omly assigned to unchanged training schedules  ( team ZSC , 21 boys ; mean age , 13.2 years ) or to participate twice weekly in guided resistance training for 4 months ( team GCK , 25 boys ; mean age , 13.4 years ) . Spontaneous physical activity energy expenditure ( SpAEE ; 3-axial accelerometry for 7 days ) , muscle strength , and body composition ( dual energy x-ray absorptiometry ) were measured at 0 , 4 , and 12 months . RESULTS Baseline measures did not differ in the groups , except for higher leg and trunk strength in team ZSC . In the intervention group compared with the control group , SpAEE significantly ( P < or = .02 ) increased at 4 months ( + 25.5 % versus 0 % ) and 12 months ( + 13.5 % versus -9.5 % ) . Leg and arm strength increased because of training intervention ; all other variables were unchanged . None of these variables correlated with changes in SpAEE . CONCLUSION In boys who play ice hockey , spontaneous physical activity is inducible with resistance training ; this effect seems to be independent of changes in body composition and strength . If this was confirmed in unselected children , resistance training might be a new strategy for childhood obesity prevention programs OBJECTIVE : To study the effect of physical activity on whole body fat ( BF ) , its regional deposition and the influence of body fatness on physical performance in prepubertal children . DESSIGN : Cross-sectional study .SUBJECTS : A total of 114 boys ( 9.4±1.5 y , Tanner I – II ) , r and omly sample d from the population of Gran Canaria ( Spain ) , 63 of them physically active ( PA , at least 3 h per week during the previous year ) and 51 nonphysically active ( non-PA ) .  MEASUREMENTS : Body composition ( DXA ) , anthropometric variables ( body circumferences and skinfolds ) and physical fitness were determined in all subjects . RESULTS : The PA obtained better results in maximal oxygen uptake , isometric leg extension force , vertical jump ( muscular power ) , and 300 m ( anaerobic capacity ) and 30 m running tests ( speed ) than the non-PA . A lower percentage of body fat ( % BF ) ( 4 U less , P<0.05 ) , whole BF mass ( 36 % less , P<0.05 ) and regional fat mass ( 28 , 25 , and 30 % less in the trunk , legs and arms , respectively , all P<0.05 ) was observed in the PA compared to the non-PA . The waist and hip circumferences correlated more closely with both the fat mass accumulated in the trunk region and the % BF ( r=0.81–0.95 , P<0.001 ) than the waist-to-hip ratio ( WHR ) . The WHR correlated with the percentage of the whole fat mass accumulated in the trunk ( PFT ) ( r=0.52–0.53 , P<0 
    Output:
    
agent
Results There was consistent evidence for a positive association between MF and physical activity .
For both MF components , there was support for objective ly measured physical activity , particularly for activity of vigorous intensity .
Sports participation was also consistently linked with both MF components , whereas the association with active transport was inconsistent .
For both MF components , associations with sedentary behaviors were inconsistent irrespective of measurement method , and the association between MF and sleep was considered uncertain .
Conclusions The available evidence supports a link between MF and physical activity , particularly for vigorous intensity activity and organized sports participation .
***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: OBJECTIVE To analyze socioeconomic indicators , physical activity ( PA ) opportunities , and behavioral correlates of cardiorespiratory and muscular fitness among Brazilian boys and girls . METHODS A sample of 1555 adolescents was r and omly selected . Age- and sex-specific st and ard scores were calculated for each fitness component . RESULTS Among boys , head of household 's schooling , involvement in organized PA , meeting the PA recommendations , and computer/games use were associated with cardiorespiratory fitness . Involvement in organized PA and active time in Physical Education ( PE ) classes were predictors of muscular fitness . Among girls , active time in PE classes and TV watching were predictors of cardiorespiratory fitness . Meeting the PA recommendations was associated with muscular fitness . CONCLUSION PA variables and sedentary behaviors should be independently considered for physical fitness promotion in youth Overwhelming evidence shows the quality of reporting of r and omised controlled trials ( RCTs ) is not optimal . Without transparent reporting , readers can not judge the reliability and validity of trial findings nor extract information for systematic review s. Recent method ological analyses indicate that inadequate reporting and design are associated with biased estimates of treatment effects . Such systematic error is seriously damaging to RCTs , which are considered the gold st and ard for evaluating interventions because of their ability to minimise or avoid bias . A group of scientists and editors developed the CONSORT ( Consoli date d St and ards of Reporting Trials ) statement to improve the quality of reporting of RCTs . It was first published in 1996 and up date d in 2001 . The statement consists of a checklist and flow diagram that authors can use for reporting an RCT . Many leading medical journals and major international editorial groups have endorsed the CONSORT statement . The statement facilitates critical appraisal and interpretation of RCTs . During the 2001 CONSORT revision , it became clear that explanation and elaboration of the principles underlying the CONSORT statement would help investigators and others to write or appraise trial reports . A CONSORT explanation and elaboration article was published in 2001 alongside the 2001 version of the CONSORT statement . After an expert meeting in January 2007 , the CONSORT statement has been further revised and is published as the CONSORT 2010 Statement . This up date improves the wording and clarity of the previous checklist and incorporates recommendations related to topics that have only recently received recognition , such as selective outcome reporting bias . This explanatory and elaboration document-intended to enhance the use , underst and ing , and dissemination of the CONSORT statement-has also been extensively revised . It presents the meaning and rationale for each new and up date d checklist item providing examples of good reporting and , where possible , references to relevant empirical studies . Several examples of flow diagrams are included . The CONSORT 2010 Statement , this revised explanatory and elaboration document , and the associated website ( www.consort-statement.org ) should be helpful re sources to improve reporting of r and omised trials Aims : To investigate how physical activity , physical performance and sociodemographic characteristics at the age of 16 are related to adult health habits ( physical activity , dietary intake , smoking ) and biological risk factors for cardiovascular diseases ( being overweight , low aerobic fitness , unfavorable levels of serum lipids , high blood pressure ) . Methods : A r and omly selected group of 220 male and 205 female students at 16 years of age was tested in 1974 , and reinvestigated 18 years later . Results : The predictive health profiles for adult lifestyle and biological risk factors were different in men and women . Leisure sports activity along with high performance in the nine-minute run among the boys and in the two-h and lift test among the girls were significant predictors of adult physical activity . A positive attitude to aerobic exercise  and high performance in the nine-minute run test among the boys and high marks in physical education among the girls decreased the risk of smoking .  Leisure sports activities together with body mass index at young ages were the most powerful predictors of adult biological risk factors , but attitudes to sports and educational level were also significant determinants . Conclusion : These results contribute to the knowledge of which factors at young ages may promote adult healthy habits in particular physical activities BACKGROUND Rural children are at a particular high risk for obesity . Given the importance of exercise in obesity and chronic disease prevention , this study evaluated the level and relationship between physical activity and fitness in a sample of rural third grade rs . The second purpose of the study was to determine potential differences in physical activity and fitness level by weight status in this sample . METHODS Twelve schools participating in a multidisciplinary research project were r and omly selected for the study . Body mass index-for-age percentile , the modified Self-administered Physical Activity Checklist  , and the FITNESSGRAM battery tests were utilized to determine children 's weight status , physical activity , and fitness level , respectively . RESULTS Thirty-eight percent of the 237 participating children ( 9.2 ± 0.4 years ) were overweight or obese . Nearly 15 % were extremely obese . Children spent 91.8 ± 83.8 and 32.2 ± 47.7 minutes in moderate- and vigorous-intensity activities . Obese children spent less time in moderate-intensity activity ( p < .01 ) and combined moderate- and vigorous-intensity activity more than other children ( p < .05 ) . Forty-three percent of all children failed to meet the fitness st and ard for muscular strength and 36 % failed to meet it for flexibility . CONCLUSIONS Rural children in this sample had higher rates of obesity compared to the national average ; they had poor fitness and 30 % failed to meet the minimum physical activity recommendations on the previous day . Future interventions should focus on increasing physical activity , especially of moderate-intensity , and improving physical fitness in order to reduce obesity and decrease the risk of future chronic diseases in this high-risk population BACKGROUND Childhood obesity has been inconsistently associated with decreased levels of physical activity and fitness . Moreover , little is known about this relationship among Filipino preteens . METHODS This cross sectional study reports the association between childhood obesity , measures of physical activity , and fitness .  Children aged 11 to 12 from r and omly selected schools from San Juan , Metromanila were included . Outcome measures were body mass index , Filipino modified Physical Activity Question naire for Older children ( F_PAQ-C ) ,  st and ing broad jump , 50 m sprint  and  20 m multistage shuttle run .  RESULTS 380 children participated in the study . Obese children had significantly lower median scores in the F_PAQ-C compared with overweight children . Overweight children had lower scores in the st and ing broad jump , 50 m sprints and predicted VO2max as compared with children with normal BMI . There were modest associations between the 50 m sprint , predicted VO2max , and F_PAQ-C. CONCLUSION Our study has showed that physical activity and fitness scores were strongly correlated with childhood obesity . If childhood physical fitness is a predictor of physical fitness in adulthood which is a risk factor in cardiovascular diseases , there is a strong possibility that the prevalence of cardiovascular disease in the Philippines will increase dramatically in the future The aims of this study were to investigate whether  physical activity ( PA ) and sedentary time ( ST )  in 9- and 15-year-olds differed between 2005 - 2006 and 2011 - 2012 ( secular change ) , and to investigate changes in PA and ST from age 9 to 15 ( longitudinal change ) . In 2005 - 2006 , we invited nationally representative sample s of Norwegian 9- ( n=1470 ) and 15-year-olds ( n=1348 ) to participate . In 2011 - 2012 , we invited a new nationally representative sample of 9-year-olds ( n=1945 ) , whereas 15-year-olds ( n=1759 ) were invited to participate either based on previous participation in 2005 - 2006 or from a r and om sample of schools . We assessed PA and ST objective ly using accelerometers . In 2011 - 2012 , both 9- and 15-year-olds spent more time sedentary ( ≥35.7 min/d , P<.001 ) and less time in light PA ( ≥35.2 min/d , P<.001 ) compared to their peers in 2005 - 2006 . Nine-year-old girls also spent less time in moderate-to-vigorous PA ( MVPA ) ( 4.2 min/d , P=.041 ) . In both age groups , the proportion accumulating an average of 60 min/d of MVPA did not differ between the two cohorts . From age 9 to 15 , girls and boys decreased their time spent in LPA ( ≥106.7 min/d , P<.001 ) and in MVPA ( ≥20.8 min/d , P<.001 ) . During the same period , ST increased by a mean of > 2 h/d ( P<.011 ) . We observed an adverse secular change in PA from 2005 - 2006 to 2011 - 2012 among 9- and 15-year-olds , and a large decline in PA in the participants followed longitudinally from age 9 to 15 years Objective To investigate the associations between body composition , cardiorespiratory and muscular fitness in relation to travel mode to school in children and adolescents . Method Children and adolescents from 40 elementary schools and 23 high schools representing all regions in Norway were invited to participate in the study . Anthropometry , cardiorespiratory and muscular fitness  were tested at the school location . Question naires were used in order to register mode of transport to school , age , gender and levels of leisure time physical activity . Results A total of 1694 ( i.e. 60 % of all invited participants ) children and adolescents at a mean age of 9.6 and 15.6 respectively ( SD = 0.4 for both groups ) were analyzed for associations with physical fitness variables . Males cycling to school had lower sum of skin folds than adolescents walking to school . Higher cardiorespiratory fitness in adolescents and male cyclists compared to walkers and passive commuters were observed . Among children , cycling and walking to school , higher isometric muscle endurance in the back extensors compared to passive commuters was observed . Conclusion Based on this national representative cross-sectional examination of r and omly selected children and adolescents there is evidence that active commuting , especially cycling , is associated with a favourable body composition and better cardiorespiratory and muscular fitness as compared to passive commuting OBJECTIVE To test the hypothesis that resistance training may increase spontaneous physical activity in children . STUDY DESIGN Two junior ice hockey teams were r and omly assigned to unchanged training schedules  ( team ZSC , 21 boys ; mean age , 13.2 years ) or to participate twice weekly in guided resistance training for 4 months ( team GCK , 25 boys ; mean age , 13.4 years ) . Spontaneous physical activity energy expenditure ( SpAEE ; 3-axial accelerometry for 7 days ) , muscle strength , and body composition ( dual energy x-ray absorptiometry ) were measured at 0 , 4 , and 12 months . RESULTS Baseline measures did not differ in the groups , except for higher leg and trunk strength in team ZSC . In the intervention group compared with the control group , SpAEE significantly ( P < or = .02 ) increased at 4 months ( + 25.5 % versus 0 % ) and 12 months ( + 13.5 % versus -9.5 % ) . Leg and arm strength increased because of training intervention ; all other variables were unchanged . None of these variables correlated with changes in SpAEE . CONCLUSION In boys who play ice hockey , spontaneous physical activity is inducible with resistance training ; this effect seems to be independent of changes in body composition and strength . If this was confirmed in unselected children , resistance training might be a new strategy for childhood obesity prevention programs OBJECTIVE : To study the effect of physical activity on whole body fat ( BF ) , its regional deposition and the influence of body fatness on physical performance in prepubertal children . DESSIGN : Cross-sectional study .SUBJECTS : A total of 114 boys ( 9.4±1.5 y , Tanner I – II ) , r and omly sample d from the population of Gran Canaria ( Spain ) , 63 of them physically active ( PA , at least 3 h per week during the previous year ) and 51 nonphysically active ( non-PA ) .  MEASUREMENTS : Body composition ( DXA ) , anthropometric variables ( body circumferences and skinfolds ) and physical fitness were determined in all subjects . RESULTS : The PA obtained better results in maximal oxygen uptake , isometric leg extension force , vertical jump ( muscular power ) , and 300 m ( anaerobic capacity ) and 30 m running tests ( speed ) than the non-PA . A lower percentage of body fat ( % BF ) ( 4 U less , P<0.05 ) , whole BF mass ( 36 % less , P<0.05 ) and regional fat mass ( 28 , 25 , and 30 % less in the trunk , legs and arms , respectively , all P<0.05 ) was observed in the PA compared to the non-PA . The waist and hip circumferences correlated more closely with both the fat mass accumulated in the trunk region and the % BF ( r=0.81–0.95 , P<0.001 ) than the waist-to-hip ratio ( WHR ) . The WHR correlated with the percentage of the whole fat mass accumulated in the trunk ( PFT ) ( r=0.52–0.53 , P<0 
    Output:
    